Background: According to Egyptian pictograms and medical records, non-surgical periodontal treatment (NSPT) has been practised for a very long time. Several clinical studies have depicted relevant clinical results when subgingival irrigation was carried out as an adjuvant therapy to SRP. This study aims to compare essential oils as subgingival irrigant agents with chlorhexidine gluconate (CHX) and sterile saline over a period of 21 days. Setting and Design: This is a comparative study of three groups (chlorhexidine group, essential oil group, sterile saline group). Each group had ten patients having chronic periodontitis who were randomly assigned and treated with subgingival irrigants. For, the essential oil group, the irrigant was indigenously prepared at chairside. Material and Methods: Following the initial examination and selection of patients, clinical parameters were noted and collection of plaque samples was done. These samples were then sent for microbiological assay at baseline. SRP was done along with subgingival irrigation at baseline, 7th and 14th day. Clinical parameters were monitored again and plaque samples were sent for microbiological test on the 21st day. Results: There was no significant difference noted between the groups in any of the clinical parameters. However, regarding microbiological parameter, better results were demonstrated in CHX group and essential oil group compared to sterile saline group that was statistically significant. CHX and essential oil group demonstrated no statistical difference. Conclusion: The result of this study suggests that essential oils can be used as a subgingival irrigant in the treatment of chronic periodontitis.

Entrepreneurship plays a significant role in pursuing economic diversification to address too much reliance on oil and gas which was estimated in 2012 to last for 20 years. Entrepreneurship program/education was introduced to various higher educational institutions across all programs and disciplines to encourage and equipped the students to engage in a business that can also address increasing unemployment through job creation. However, most of the students preferred to be wage employees. A focus group was created and identified student priorities which are categorized according to Opportunities, Motivation, and Incentives. 243 out of 658 Advanced Diploma and Bachelor students of UTAS-Shinas were selected through a combination of purposive sampling and simple random sampling. A survey questionnaire was used to gather data on student priorities or factors using a 5-point Likert scale and the data were analyzed using sample mean and two-tailed independent sample t-test. Results showed 62.14% of the respondents preferred to be wage employees. Respondents also agree that opportunities and incentives contribute to entrepreneurship success however, respondents do somewhat agree that motivations could contribute to entrepreneurship success with a mean of 2.69. Results suggest that there is a statistically significant difference in the response based on academic level, after graduation preference, and existing (family-owned) business with a p-value of p=0.013, p=0.002, and p=0.005 respectively except gender p = 0.064. The result signifies that while students’ priority leads to entrepreneurship program success, respondents greatly rely on the sustainability and the intensity of future monetary benefits and economic incentives. Though the academic and government/private finance and technical support elements of the model may be assumed to work perfectly, the success of the entrepreneurship program warrants collaborative effort to initiate a paradigm shift on students’ priorities/factors.

The present electrochemical study deals with the evaluation of a complexation process involving different metal and ligands and its physicochemical properties to find out the ligand- metal ratio of complex in solution. For the determination of complexing nature “Monovariation method” have been used to ascertain the ligand metal ratio in the complex. The stability constant of the formed complexes were calculated by conductance measurement using Modified Job’s method (Turner Anderson Method). The analysis had been carried out by using conductometric principle and the final outcome of the experiment may influenced by temperature and with the ionic concentration of metal and ligand solution. Free energy change values were determined to find out the feasibility of the complexation process. One of the method was validated statistically by using system and method precision parameters. Lastly the complexes was been assayed by using a specific chromogenic agent with a specific spectroscopic technique that may give biological action in future.

Acute myeloid leukemia has been classified on the basis of morphology, cytochemistry and genetic profile. IDH gene is an epigenetic modifier whose mutation is involved in pathogenesis of various malignancies. This study was planned to study the prevalence of IDH1/2 mutation in denovo AML cases at a tertiary care Centre in North India and also to study its clinicopathological effect in these cases. We evaluated 60 patients registered at our Centre for diagnosis and treatment of AML. Routine investigations, bone marrow examination, flow cytometry were done followed by PCR and sequencing. Out of the total 60 patients of AML 4(6.7%) patients had IDH1R312 mutation and 5(8.3%) Patients had IDH2R172 mutation. IDH2 R140 mutation was not detected in any sample. IDH mutation was significantly associated with high risk AML group. No significant clinicopathological correlation was seen. In this study significant association was observed between IDH mutation and high risk AML cases. There was no paediatric case with IDH mutation. IDH mutation and AML might have an age related association.

Background: Hundreds of thousands around the world die from a disease caused by smoking cigarettes. Cigarette smoking (CS) is considered a worldwide major cause of preventable morbidity and mortality. The main clinical consequences of prolonged exposure to CS are chronic respiratory diseases, increased incidence of a variety of cancers, cigarette smoking had a dangerous effect on the essential biochemical mechanisms on the human body. Objective: This study aimed to assess the liver function in Sudanese male cigarettes smoker to identify the influence of cigarettes smoking on the level of their parameters. Material and methods: The study was designed as case control and include 81 samples, which is divided into case (51 samples) and control group (30 samples). The data collected by the use of questionnaire and blood specimens, and the levels of the parameters is measured by A15 automation spectrophotometer. Then the collected data is analyzed by the use of SPSS. Results: The results of the study showed statistically significant increase in total bilirubin and liver enzymes in case group when compared with control group. The mean of plasma total bilirubin, GOT (AST), GPT (ALT), and ALP levels in case group is (0.663, 26.49, 18.82 and 159.27) and in control group is (0.543, 23.00, 14.30 and 146.63) with p. value (0.001, 0.041, 0.004 and 0.000) respectively. And showed statistically insignificant decrease in total protein and albumin in case group when compared with control group, the means of total protein and albumin in case group is (66.47 and 33.73) and in control group is (68.30 and 34.43) with p. value (0.322 and 0.403) respectively. Conclusion: The study concluded that there was significant increase in liver enzymes (GOT, GPT, and ALP) and total bilirubin in cigarette smoking. And significant decrease in total protein and albumin, in cigarette smoking when compared to nonsmoking.

An analgesic is any member of the group of drugs used to achieve analgesia, relief from pain without loss of consciousness. Pain is one of the devastating health problems commonly treated with medicinal plants. Dioscorea dumetorum (Kunth) Pax (Family Dioscoreaceae) is one of the popular species of yam, usually found in Africa and mostly consumed in West Africa. Tragia benthamii Bak. is an herbaceous twining or trailing plant which belongs to the Euphobiaceae family. The plant is indigenous to Ivory Coast extending wide spread across Africa including Nigeria. This study investigated the analgesic activities of Dioscorea dumetorum and Tragia benthamii leaves’ methanol extract on mice. Acetic acid-induced writhing method was engaged. Thirty-two (32) healthy and energetic mice were grouped into eight (8) of four (4) mice. Indomethacin (25 mg/kg) was administered to the positive control group, negative control group received distilled water (10 ml/kg) while each extract treatment groups received 50, 100, 200 mg/kg respectively. Analgesic activities of the plants’ extract were assessed by counting the number of writhes for 30 minutes after a latency period of 5 minutes. Reduction in the number of writhes as compared to the control groups was considered as evidence for analgesic potential of the plants. In this study, the positive control (Indomethacin), D. dumetorum and T. benthamii significantly decreased the mean number of abdominal constrictions or writhes in a dose dependent manner following the order of 200>100>50 mg/kg. The result showed that the potency of the two plants’ extract was superior to that of Indomethacin but T. benthamii (200 mg/kg) exhibited higher analgesic activity. Values of reduction time in writhing were significantly different (P<0.05) among the treatments. This research revealed effective potential analgesic effects of D. dumetorum and T. benthamii which could be attributed to the presence of phytochemicals in them. Therefore, further studies to explain their mechanisms of action should be conducted to aid the discovery of new therapeutic agents for the treatment of pains.

Acid violence is a serious issue in Bangladesh and is considered one of the worst forms of violence against women. Bangladesh is surrounded by a number of problems some of the fundamental issues also available in this country. The discrimination among the males and females is very much visible here. This article provides an overview of acid violence in Bangladesh, including its causes, consequences, and efforts to prevent and respond to the problem. The state, society, guardians and worldwide organizations need to assume reciprocal parts in disposing of this work. Specialized collaboration to legislatures, non-administrative associations and different offices in this attempt should be emphatically advanced.

Introduction: The International Continence Society (ICS) describes Urinary incontinence (UI) as the complaint of involuntary leakage of urine and proposes a classification according to the existence of signs and symptoms and mechanisms of occurrence [1, 2]. Purpose: The purpose of this review is to find existing evidence based intervention for Stress Urinary Incontinence (SUI) among women. A preliminary search on Cochrane database, PUBMED, EMBASE, SCOPUS & CINHAL done by the researcher and found relevant studies which provided strong evidence to support role of Pelvic Floor Muscle Exercises (PFME) or Pelvic Floor Muscle Training (PFMT) in reducing symptoms among women diagnosed with SUI. Conclusion: The review concluded that PFMT is a feasible and patient friendly exercise program used for treating SUI with high quality evidence and to be followed under supervision of a health professional. It is also found that less number of recent studies hence suggest having long term studies in future.

Despite barely being a novel concept, EVs have been rising in popularity because of the development of the technology and infrastructure required to support EVs on a large scale, a growing concern for the climate, and a fight to lower carbon emissions. Even though the demand for EVs rising every year, there have been a few major roadblocks that are affecting the growth and development of EVs in developing countries and households with lower incomes, specifically the high initial cost of building the infrastructure of EVs, EVs being more expensive than regular Internal Combustion Engine cars, and a skeptical consumer market. However, making conversions of ICEs into EVs or Plug-in Hybrid EVs (PHEVs) might circumvent many of these issues, including combating the problem of replacing every single ICE with a brand-new EV in the span of a few decades. This paper discusses the cost, efficiency, and public perception of converting ICEs to EVs and what a viable business model can look like while paying particular attention to customer needs and public perception.

FDI is one of the important pillar for the development of economic sectors and industries for promoting the high growth of valuable products and improve the quality of useful industrial products. However, as a result of globalization, a country's economic development is no longer completely reliant on its own resources. The foreign direct investment (FDI) made by multinational corporations improves the quality of life for locals by creating employment for them and raising their level of living. FDI may have both positive and negative effects on the expansion of the economy, depending on the factors. South Asia's leading liberal economy is Pakistan. Pakistan permits 100% foreign ownership in its secondary industry due to its open economy and fast-paced private sector. Pakistan's tertiary sector has seen a sharp growth in FDI inflows when compared to other economic sectors. Pakistan's primary sector of the economy is characterised, like other emerging countries, by poor productivity, inefficient labour, energy deficits, and less incentives. However, it seems that the incentives and other variables have only had a modest impact on Pakistan's FDI levels in recent years. The economic development of Pakistan is negatively impacted by foreign direct investment. FDI has a significant influence on Pakistan's short- and long-term economic development.

This study aims to test whether the moderation of regional financial supervision can affect the accountability of regional financial reports and the sensitivity of the budget to SKPD performance. The population and samples selected in this study were regional work units (SKPD) in the DKI Jakarta area, questionnaires which would be distributed to regional work units (SKPD) in the DKI Jakarta area with a total of 246 samples. The software used is SmartPLS (partial least square). The results of hypothesis testing in this study found that regional financial accountability has a positive effect on SKPD performance, budget sentiment has a positive effect on SKPD performance, regional financial supervision has a positive and significant effect, regional financial supervision can strengthen the influence of regional financial accountability on SKPD performance and moderation on regional financial supervision is not able to strengthen the effect of budget transparency on SKPD performance. The results of this fifth hypothesis research are to prevent such a situation, SKPD should be able to improve regional financial supervision so that ASN as government employee can preparing the budget have information about public finances, because ASN as government employee that have information complexity about public finances may have optimal SKPD performance .

Milk thistle (Silybum marianum L.) is a baceous plant that belongs to the Asteraceae (daisy) family and is a member of the Carduae clan. Since antiquity, a several diseases has been treated by milk thistle such as to treat liver problems, spleen problems, gallbladder problems, hepatitis, and gallstones. Milk thistle seeds are utilized in herbal remedies, and there are six flavonolignans that make up silymarins: silychristin, silydianin, silybin A& B, isosilybin A & B. Because of its membrane-stabilizing qualities, silymarin is effective in chronic liver disorders. Many disorders, such as anti-cancer, anti-diabetic, anti-hypertenshaion, and anti- Alzheimer's, are caused by S. Marianum. Milk thistle is now utilized in a diversity of supplements, including oil seed and capsules of soft gel.

Background: Abortion or miscarriage is a common health intervention. Incomplete abortion is a term given to miscarriage where there are retained product of conception still within uterus. Complications of incomplete abortion includes haemorrhage, infection, shock even DIC (Disseminated intravascular coagulation). Treatment of incomplete abortion has traditionally been surgery like D&C or MVA. Though these treatments are effective but they require specialized equipment, trained person and associated with dangers like uterine trauma, perforation, bleeding to instrumentation, infection & reaction to anaesthesia. For these reasons determining an effective nonsurgical approach for treatment of incomplete abortion is important. Materials & Methodology: During the period of June 2021 to December 2022, 100 women diagnosed as incomplete abortion, were selected in Popular Diagnostic Centre (Badda, Dhaka) and in US-Bangla Medical College Hospital (Narayanganj) as per inclusion criteria and treated with Tablet Misoprostol 6ooµg orally and success to treatment was noted. Results: Treatment was found successful in 94% cases. 6% Cases needed MVA. Among 94% cases 32% was successful after 1st dose of Misoprostol and 62% was after 2nd dose of Misoprostol. Conclusions: Oral Misoprostol is very effective method with high patient satisfaction.

Many plant species have their own toxicity, direct or indirect. On this point, the perfect knowledge of the metabolite constituents of the plants as well as the toxicity related to them is necessary for an adequate use in the formulation of the Improved Traditional Medicines and all other products related to the plants. Our study aims to carry out the quantitave screening and the study of the subchronic toxicity of ethanolic extract of the stem bark of Canarium schweinfurthii. Harvested in Bamendjou in the West Cameroon region, the stem bark of C. schweinfurthii was extracted with ethanol at 700. The estimation of total polyphenols, total flavonoids, tannins, saponins and alkaloids has been evaluated by different methods described in the literature. The subchronic toxicity assessment was performed over a 90-day period, with 4 batches of 10 rats (5 males and 5 female’s albino Wistar rats) following OECD 408 guidelines. The determination of biochemical parameters, and hematological parameters was done in serum and histological sections on organ. Among the quantified compounds, saponins were the most abundant followed by polyphenols, alkaloids, then flavonoids and finally tannins. On repeated dosing for 90 days, the extract contributed to non-significant weight growth in rats at all dose levels in both male and female rats. Analysis of biochemical, hematological and histological parameters and histological sections did not show any serious signs of toxicity in the treated groups. Finally, the ethanolic extract of the stem bark of C. schweinfurthii even rich in secondary metabolites appears to conserve an acceptable safety for the formulation of improved traditional medicines.

Background: The perioral region plays an important role in facial recognition, gender classification, esthetics, facial expression, speech and eating. Aim: To establish normative perioral data for South-East, Nigerian children Methods: A sample of 120 healthy subjects within the age range of 1 to 5 years were enrolled in this study. Two dimensional photographs of the face were captured non-invasively using a Nikon D 90 camera, ten perioral landmarks were identified and four indices deduced Results: It was observed that vertical mouth height index, upper lip thickness and lip index in the males showed higher values when compared to the females which indicates sexual dimorphism (P≤0.05). Most children in our cohort were classified as having a thick lip index, mouth of intermediate height in relation to the height of the face, thick upper and lower lip thickness index, narrow mouth in relation to the width of the eyes. The mean values of Vermillion height of Lower lip and Lower Lip Thickness Index was also observed to be consistently higher when compared to upper lip in both sexes. Conclusion: The study presents a primary data base for perioral anthropometric indices of children in South-East Nigerian which can aid ethnic specific postoperative evaluation of congenital or post-traumatic orofacial reconstructive surgeries.