Marriages carried out between husband and wife, sometimes cannot run as the purpose of marriage. If it cannot be maintained, then the path taken is divorce. In Article 19 Paragraph (4) states that the reason that can be used in filing for divorce is that one party commits cruelty or severe abuse that endangers the other party which is also a form of domestic violence and can be the cause of disputes and conflicts that occur in the household. Acts of domestic violence are not limited to physical violence in the form of abuse such as: slapping, hitting, kicking and even killing. As for the form of persecution that is psychological or psychological violence. Research Objectives: To analyze what are the current weaknesses in the Regulation on Reasons for Filing Divorce Due to Domestic Violence; To find out how to reconstruct the Law on Reasons for Filing Divorce Due to Domestic Violence based on justice. The research method uses the Constructivism Paradigm with non-doctrinal legal research with an empirical juridical approach. The study results show that (1) Weaknesses in the Regulation on Reasons for Filing for Divorce Due to Domestic Violence. Weaknesses in a legal substance: Elucidation of Article 39 Paragraph (2) of the Marriage Law and Article 19 letter d of Government Regulation 9 of 1975 only provides rules for physical violence. Weaknesses in the legal structure: The weak mentality of law enforcement officials results in law enforcement not working as it should. Weaknesses in legal culture: Domestic violence is a problem that is closely related to gender bias which is common in patriarchal societies. (2) Reconstruction of Regulations on Reasons for Filing Divorce Due to Acts of Domestic Violence. The formulations in Article 39 Paragraph (2) and the Explanatory Articles of the Marriage Law do not contain forms other than physical violence, such as psychological violence and sexual violence.

Melkersson-Rosenthal syndrome (MRS) is defined by the triad of labial edema, peripheral facial paralysis, and plicated tongue. It is a complex entity with clinical polymorphism and unknown etiopathogenesis. A better understanding of the pathophysiological mechanisms would improve the management of these patients, who often present with significant aesthetic damage. We report a rare case of this syndrome with a plicated tongue and sequellar lagophthalmos.

Described since the 15th century by Ambroise Paré, adult hydrocele is an abnormal collection of serous fluid in the space between the parietal and visceral layers of the tunica vaginalis It is generally a lesion acquired by attack of the integrity of the vagina, unlike the hydrocele of the child due to the persistence of the peritoneal-vaginal canal. Purpose: To study the epidemiological, clinical and therapeutic aspects of hydrocele in the reference health center of Fana. Methodology: A descriptive prospective study, conducted from January 1, 2020 to December 31, 2020 of the CSRéf of Fana. Results: We collected 66 cases of hydroceles be 16.8% of surgical activities. The average age of disease was 49.27 ± 4 years. The age of 60 to 74 was the most represented with a frequency of 39.4%; Harming during physical activities has been the most common reason for consultation and accounted for 51%. The hydrocele was idiopathic in the majority of our patients in our study, or 65%. The nature of the vaginal fluid was yellow citrin in the majority of patients or 90.9%. Hernie was the most frequently associated pathology with the hydrocele (11 out of 26) or 42%. The Bergman technique was used in 77% of patients and closing the peritoneo-vaginal canal in 23%. Morbidity was 4.5% (3 cases) with hematoma type and 1.5% (1 case) with type of infection. The mortality rate has been zero. Conclusion: Vaginal hydrocele is a pathology that remains frequent in tropical regions. Surgical treatment by total vaginal resection with hemostatic overlock gives good results. Its morbidity is low, dominated by intrascrotal hematoma and infection of the surgical site which are generally well controlled by rigorous care.

To achieve a more appealing smile, an orthodontic technique known as Invisalign might be utilised. Invisalign procedures may be beneficial if you have an overbite, crossbite, or deepbite. Transparent plastic aligner trays are used to gradually straighten the teeth during the operation. Patients may maintain their oral health and wellbeing by simply removing the trays, without having to worry about brackets and wires that may make it difficult. The primary goal of this study is to evaluate previous studies and review all available evidence on how Invisalign can treat deep bites. The comprehensive search will use Medline, PubMed Central, Embase, and other databases. The literature review is completed in English with the goal of reviewing the material that describes how Invisalign can treat deep bites. In recent years, the importance of appearance in personal and professional lives has spurred significant interest in orthodontic treatment among adults. The transparency of the Invisalign appliance boosts its visual appeal for mature patients who are hesitant using conventional labial fixed braces.

Avicennia marina is a commonly found mangrove species in coastal regions, and is known for its medicinal properties. In this study, the antibacterial and antifungal activities of ethanolic extract of Avicennia marina leaves were evaluated against MDR microorganisms. The antimicrobial activity of the extract was assessed against a range of bacterial strains, including Salmonella sp. (MDR), Klebsiella sp. (MDR), Pseudomonas sp. (MDR), Acinetobacter sp. (MDR), Staphylococcus aureus as well as the fungal strain Candida albicans (ATCC 10231), Candida parapsilosis (ATCC 22019). The results showed that the leaf extracts of Avicennia marina exhibited significant antimicrobial activity against all tested MDR microorganisms. The phytochemical content of the plant includes many bioactive compounds - flavonoids, tannins, and alkaloids, which may be responsible for the observed antimicrobial activities. These findings suggest that Avicennia marina may be a potential source of natural antimicrobial agents, which could be used to develop new drugs for the treatment of resistant bacterial and fungal infections. Further studies are needed to identify and isolate the active compounds responsible for the observed activity and to evaluate their efficacy and safety in vivo.

The aim is to study acute appendicitis in the surgery department of the Markala Reference Health Center. Patients and Methods: We conducted a retrospective study in the general surgery department of the reference health center which took place over a period of 35 months from October 1, 2019 to October 30, 2021. The retrospective period was from the month of October 2019 in October 2020 then follows the prospective period until October 2021. Inclusion criteria: Were included in our study; all patients with appendicitis or its complicated forms in the general surgery department of the Csréf in Markala. Non-inclusion criteria: Were not included in our study; cases of appendicitis outside the general surgery department of the Csréf. -Appendicitis accounted for 58.2% of hospitalizations or 31% of emergency surgeries performed during the study period. 85.4% of the patients were without medical-surgical ATCD, on the other hand the oldest of our patients was 61 years old; the average age was 29 years old and the youngest was 13 years old. Furthermore, we note that there was no age of onset of appendicitis. The treatment received by all of our patients was appendectomy (93 cases were operated on urgently and the 10 cases were first cooled and then operated on 3 months after the medical treatment). No major complication was noted in our patients, apart from three cases of infection of the surgical site related to the fact that it was an appendicular abscess. Conclusion: Acute appendicitis is one of the most common surgical emergencies in digestive surgery. Its diagnosis is essentially clinical, sometimes made difficult by the absence of anatomo-clinical parallelism linked to the polymorphism of the lesions and the variations in the position of the organ in the abdominal cavity. Untreated, it can progress to serious complications (generalized peritonitis). It is a condition with low morbidity and mortality subject to early diagnosis and surgical treatment.

Complexities of root canal system necessitate the use of irrigation along with their activation to achieve complete cleaning. Common methods include sonic and ultrasonic activation of the irrigants. A newer rotary file system, XP-Endofinisher has the advantage of elliptical movement resulting in efficient cleaning. 24 single canalled maxillary anterior teeth were selected and divided into 3 groups, Group 1- XP (n=12), Group 2- PUI (n=12), Group 3 – Endoactivator (n=12). All samples were prepared with Protaper Universal files and irrigated with 5.25% sodium hypochlorite & 17% EDTA. In Group 1- XP-Endofinisher at 800rpm for 1 min; Group 2- i-SuperTip in EMS scaler for 1 min; Group 3- Endoactivator for 1 min. Specimens were filled with Cerafill and then sectioned horizontally with a water-cooled diamond saw at depths of 4, 7 and 10mm to produce 1mm slices. POBS was performed, bond strength in MPa was obtained after dividing the load at failure by the area of the bonded interface. POBS of Cerafill to root dentin of Group 1 was significantly more than that of Group 2 and 3 (p≤0.05) at all three levels. Group 2 was better than 3 at all levels but difference was not significant. In Group 1, POBS was significantly more at 4mm compared to 7mm and 10mm (p≤0.05). Use of XP- Endo Finisher after biomechanical preparation improves the POBS of bioceramic based sealer to root dentin at 4, 7 and 10mm. POBS of sealer after PUI was marginally better than Endoactivator at all levels.

Nine existing sunshine based models and three existing temperature based models were evaluated and compared to ascertain the most suitable models for estimating global solar radiation in Maiduguri; the most suitable sunshine based and most suitable temperature based models were also compared. The measured monthly average daily global solar radiation, sunshine hours, maximum and minimum temperature meteorological parameters during the period of thirty one years (1980 – 2010) was utilized and the evaluated models were tested statistically using validation indicators of coefficient of determination, Mean Bias Error, Root Mean Square Error, Mean Percentage Error, t – test, Nash – Sutcliffe Equation and Index of Agreement. The results indicated that the linear exponential sunshine based model and the logarithmic temperature based model were found more accurate for global solar radiation estimation in Maiduguri as compared to other evaluated models. Furthermore, the logarithmic temperature based model was found more accurate for estimating global solar radiation as compared to the linear exponential sunshine based model, and this was testified from the figure showing the comparison between the recommended sunshine based and temperature based models in which the recommended temperature based model depicts the best fitting with the measured global solar radiation data.

To study the epidemiological-clinical profile of sickle cell patients in the health district of Bla. Method: This was a prospective and descriptive study over 1 year, from February 2021 to January 2022; relating to all patients who were screened with the TDR_Sikle Scan and/or followed up during the study period. Results: We performed the TDR in 982 patients from all the consultations (N= 2976). The mean age was 29.6 ± 3.8 years. SS and SC sickle cell disease represent 8.04% (79 cases). Children 23.52% (28 patients) and women 64.35% (51 patients). SS married couples represented (13.92%). Anemia was the most common reason for consultation (47%), followed by bone and joint pain (29%). 33% of the patients (26 cases) had a complication, of which 15 patients had had a CVO and 6 patients (23%) a worsening of the anemia. We have recorded 1 death. Conclusion: regular medical follow-up of sickle cell patients considerably improves the vital prognosis. The frequency of sickle cell traits remains high including SS and SC forms.

Artificial intelligence is defined as "the study and improvement of computer systems capable of performing tasks typically requiring cognitive abilities, such as image perception, speech recognition, decision making, and language translation." When a computer imitates analytical traits such as "learning and problem-solving," which humans normally connect with other human brains, the term "AI" is employed. A profusion of studies and papers on the function of AI in restorative dentistry have been published in recent years, with the majority of the efforts focusing on recognising and diagnosing dental disorders such as caries, gum disease, and tooth fractures. The major purpose of this study is to undertake a thorough review of prior research on the impact of artificial intelligence on restorative dentistry. The relevance of the theme tooth reconstruction was prioritised during the search. AI has achieved important improvements in a wide range of medical fields, most notably in dentistry for the diagnosis, localization, classification, estimation, and assessment of dental disease. This review only covers seven papers on the impact of AI on restorative dentistry. Artificial intelligence (AI) has advanced significantly as a powerful tool for computerised tooth repair during the previous two decades. More study is needed, however, to compare different types of AIs and assess their clinical usefulness in occlusal interface restoration.

This study highlights the basic features of Bloom’s Taxonomy and its importance in integrated teaching- learning-assessment system. This study detailed a plan of information and Communications Technology (ICT) based implementation of revised Bloom’s taxonomy (2001) as a mark of examination reform to analyze students’ attainment level by measuring knowledge level (K), course outcome (CO) and program outcome (PO) in respect to each curriculum. The plan ultimately facilitate to develop a portal and fulfil the basic objective of Outcome based Education (OBE) system as the students’ attainment report is one of the required field for accreditation by National Assessment and Accreditation Council (NAAC).

Diabetes mellitus is a chronic condition characterized by major derangements in glucose metabolism and abnormalities in fat and protein metabolism. Diabetes and infection are among the serious health challenges. This study evaluated the in vitro and hypoglycemic effect and antimicrobial properties of methanol extract of Ipomoea batatas leaf. The antimicrobial activity was done using agar disc diffusion methods and the in vitro hypoglycemic activity was done using Alpha-Glucosidase Inhibitory activities assay, Lipase activity assay, Glucose absorption Capacity assay, Glucose diffusion retardation Index. The result of the percentage alpha glucosidase inhibition ranged from 35.70 to 56.33%. The percentage alpha amylase inhibition ranged from 40.96 to 65.15%. The extract showed significant (p<0.05) dose dependent inhibition of alpha glucosidase and alpha amylase. The extract possess inhibition of lipase activity with percentage inhibition ranging from 72.35 to 81.57%. Though there was non-significant (p<0.05) difference in the various concentrations of the extract on inhibition of lipase activity. The result of the glucose absorption capacity (0.30 to 2.25) was observed to be dose dependent. The glucose diffusion retardation index was time dependent. The antimicrobial susceptibility screening of extracts showed a zone of inhibition that ranged from 2.70 to 15.73mm. The study showed that Ipomoea batatas leaf could be used in the treatment and management of diabetes and infections.

Background/Objectives: Diabetes is frequent among cancer patients. Diabetes and cancer co-occurrence may result in a worse prognosis and complications in cancer patients. This systematic review aims to investigate the impact of glycemic control in patients having both cancer and diabetes. Methods: PubMed, Web of Science, Science Direct, and Google Scholar were systematically searched to include the relevant literature. Rayyan QRCI was used throughout this systematic approach. Results/ Interpretation: A total of thirteen studies with 13550 patients were included in this review. The reported follow-up duration ranged from 2 to 12 months. Cancer patients with diabetes are more likely to get infections, be hospitalized, and require chemotherapy reductions or discontinuation. Having cancer with comorbid diabetes affects diabetes self-management and results in poor glycemic control. Applying clinical pharmaceutical programs to raise awareness about compliance with diabetic medication along with cancer treatment was found to have positive outcomes. Evidence-based practice recommendations or policies should be developed that advocate assessing diabetes patients' glycemic state at the time of cancer diagnosis.

Appendiceal mucocele is a rare pathology, which poses a double problem by its potential malignancy and the risk of peritoneal pseudomyxoma in case of perforation. We report here the case of a 57 year old patient operated for anal fistula in whom the clinical examination revealed a mass of the right iliac fossa. Ultrasound showed a cystic pericaecal mass. The patient underwent a laparoscopic appendectomy removing the caecal base and the appendicular operative specimen measured 130 mm in length and 64 mm in diameter. Pathological analysis of the specimen confirmed the diagnosis of appendiceal mucocele without malignant cells. The postoperative course was simple and the patient was discharged on the sixth postoperative day. The aim of this study was to show the diagnostic and therapeutic features of this condition in our context.

The search for dietary sources with potent biological activities has increasingly attracted considerable attention. Sweet potato leaves (SPL) are considered to be a leafy vegetable consumed by humans, which is not currently widely used, despite it possession drought tolerance, and the ability to grow in different climates and farming systems. This study evaluated the in vitro Nutraceutical and Pharmacological potential of underutilized leafy vegetable (Ipomoea batatas leaf). The phytochemicals, in vitro antioxidant and anti-inflammatory activities; mineral and vitamins compositions of the leaf were carried out using standard method. The bioactive compounds in Ipomoea batatas were identified using GC-MS. The results of the GC-MS profiling revealed n-Hexadecanoic acid (23.43%), Cyclotrisiloxane, hexamethyl (17.73%), and 16-Pregnenolone (11.30%) as the most abundant bioactive compounds in Ipomoea batata leaves. The mineral analysis showed that Ipomoea batata leaves contains favorable amount of macro elements such as Ca (915.40±9.50), K (2083.30±15.00), P (511.26±4.70), Mg (271.25±7.20), Na (9.98±1.06) and considerable amount of trace elements such as Fe (10.60±1.30), Mn (2.55±0.27), Zinc (2.70±0.11), and Cu (1.32±0.08) in which all were measured in miligram per 100g (mg/100). The vitamins such as of Vitamin A, vitamins C, vitamin E, niacin (B3), thiamine (B1), riboflavin (B2), pyridoxine (B6), vitamin D and vitamin K are present in trace amount in the leaves. The in vitro antioxidant activities of the extract showed a significant (p<0.05) dose dependent free radical scavenging activities. The anti-inflammatory analysis showed that the percent inhibition of hemolysis (20–100 µg/mL dry weight basis) was within the range of 4.1% to 18%. Percent inhibition of protein denaturation was within the range of 29.0–71.0%, Proteinase inhibitory activity was within the range of 16–30.0% and the lipoxygenase inhibition was within the range of 8.2–34.5%. This study provide validation for the usage of Ipomoea batatas leaf as new leafy vegetable with appreciable nutritional values and also provided credence to the bioactive compounds in leaf as potential novel drug candidate for pharmaceutical industries.