This is the case of a female patient aged 42, admitted for abdominal distension and abdominal pain, in whom clinical examination revealed a dysmorphic liver with signs of portal hypertension. Abdominal ultrasound coupled with Doppler showed SBC, which was confirmed by abdominal angioscan. A complete etiological workup was performed, which revealed the presence of an HPN clone on flow cytometry. The patient was put on anticoagulation in addition to treatment of the complication of PH, with a good clinical evolution. At present, the patient is still under regular consultation.

Identification and extraction of characterized information from complex high-dimensional biological data is a very meaningful issue. The dimensionality reduction fusion method based on random forest, feature extraction and neural network is proposed to recognize and classify two datasets of mRNA and lncRNA. It is shown that the proposed fusion method achieved accurate identification/classification of cancer and non-cancer groups, and simultaneously selected identity variables that have biological relevance to lung cancer (tumor) as potential biomarkers from a large number of variables. It is considered as an effective tool and theoretical support for lung cancer identification in clinical application, and it can be extended to other kinds of cancer or biological data. Ultimately, an advanced method for feature extraction and classification analysis of high-dimensional data is provided.

At the root of the social construction of nations, there are almost always founding mythologies supposed to explain the advent of this or that fact and/or phenomenon. The Koongo nation is no exception. It has a mythology that relates how the muuntu, the primordial being, in its primitive uniqueness, split into two individual entities, each retaining its specificity, and, at the same time, the trace of this ontological split. From this ontological split in primordial being came man and woman. The aim of this paper is to show how, from this ontological split, the symbolism of the woman, who has become the most prominent social figure in Koongo civilization, has imposed itself to the point of structuring the entire Koongo imaginary, so that the man is reduced to the role of stooge, charged with magnifying and dignifying the image of the woman.

Ecological discourse analysis, as an emerging discipline, aims to reveal the role of language in ecology. The transitivity system serves as a theoretical foundation, which helps to explore the ecological ideas implied in ecological discourse. William Wordsworth, a British Romantic poet, is famous for his poetry depicting natural scenery. I Wandered Lonely as a Cloud is a representative work of his nature poems. Based on the transitivity system of systemic functional linguistics, this paper conducts a deep analysis of Wordsworth's nature poem I Wandered Lonely as a Cloud from the perspective of ecological discourse analysis, exploring the basic path of the poet's expression of his ecological view through language. On the one hand, the poet regards the relationship between humans and all things in nature as a harmonious and equal dialogue partnership. He wants to advocate respect for nature, awe of nature, and oppose anthropocentrism, promoting the ecological idea of harmonious coexistence between humans and nature, which reflects his positive ecological view. On the other hand, by studying Wordsworth's ecological ideas, readers can be guided to establish a healthy ecological view, enhance their sense of ecological responsibility, and promote people's love for nature and friendship with nature.

Background & Objective: The desire for fairer skin has become a global phenomenon, with colonial remnants in South Asia being identified as contributory factors to the perception of white skin as supreme. Skin lightening products (SLPs) are commonly used to reduce melanin concentration in the skin and achieve a lighter complexion. While SLPs can be medicated for treating hyperpigmented disorders and other skin conditions, their predominant use is for brightening the skin tone. Aim: To investigate the prevalence of SLP usage among males and females in the young generation in Lahore, Pakistan, and assess their knowledge and perception of the associated risks. Additionally, the study will examine the ingredients commonly found in SLPs and their potential adverse effects. Methodology: The instrument employed for the study was self-administered Questionnaire designed by the researcher. The data collected were analyzed as descriptive and bivariate using percentages, mean and median. Result: The study found that a significant percentage of young males and females in Lahore, Pakistan, use skin-lightening products, with social media and advertisements influencing their knowledge about these products. While participants were aware of potential harm from skin-lightening creams, many could not identify the active ingredients. Study highlighted the need for more inclusive beauty standards and consumer education campaigns. The study's results contribute valuable insights into the multifaceted landscape of skin tone perceptions, skin whitening product usage, and the associated complexities. Conclusion: The findings underscore the importance of considering cultural, psychological, and health-related aspects.

This paper aimed at promoting intercultural communicative competence (ICC) through designing intercultural tourism brochures. This is expected to raise the awareness of the tourism stakeholders to the necessity of designing the intercultural tourism brochures and the tourists to insist on having pre- intercultural knowledge about the culture they are intending to have an excursion. Consequently, tourism will develop and prosper on a solid ground of intercultural understanding and diversity. The methodology of this paper was based on suggesting some tourism brochures about six different cultures and destinations. Each brochure includes, the culture, a photo of one of the landmarks, a quote from one of the icons of the targeted culture, an ICC concept, the cultural purpose and “Dos” and Don’ts”. This paper is original since it presents new and creative ideas, applies new method of promoting both tourism and intercultural understanding, and even provides a new vision for developing tourism sector. The study came up with sample tourism brochures, which interpret the concepts of intercultural communicative competence alongside promoting tourism. Consequently, the researcher recommends adopting these tourism brochures by both tourism stakeholders and individuals.

This research aims to determine the effect of digitalization of tax services and tax understanding from taxpayers on the level of taxpayer compliance by making tax sanctions as an intervening variable. The sample and population of this study are corporate taxpayers registered with the KPP at the DJP Kanwil West Jakarta. The samples collected in this study totaled 112 samples. Research data from questionnaires distributed directly to the sample. Research data processing uses Smart PLS software. The findings show that digitalization has no impact on tax sanctions or taxpayer compliance. Taxpayer's tax knowledge influences tax sanctions and Taxpayer's tax compliance. Tax sanctions have an influence on taxpayer compliance. Tax sanctions cannot intervene in the digitalization of tax services for taxpayer compliance. Tax sanctions can intervene in the Taxpayer's tax understanding towards the Taxpayer's fulfillment of tax compliance.

This paper surveys the development of the Palestinian educational system in general and the English general and the English curriculum in specific. That is, it illustrates the developmental stages of the educational system across various periods of time and the Palestinian curriculum guidelines together with the achievements. It also addresses the English curriculum of the sixth grade, and analyzes Unit 7 of the 6th Grade textbook. Consequently, some modifications were suggested regarding various skills, and the need of including cultural spots in each unit was highlighted. The researcher suggested some ideas related to the use of role-cards in teaching speaking and cultural spots to teacher reading. For speaking, the researcher planned some role cards, in which each student has a role to play, i.e offering help for the grandparents in collecting olives. For reading, a cultural paragraph about the plant of mango in India was suggested. These sample activities make connections with students experience and the culture of others.

Starch is the most abundant naturally occurring carbohydrate reserve in plants and is found in cereals, roots, tubers, legumes and some immature fruits like bananas or mangos. Starch is usually employed as a food additive, such as a thickening, stabilizer, or texture enhancer to improve some of the products quality characteristics, pharmaceutical and among other. The application of native starch is often restricted owing to its constricted solubility, weak functional attributes and limited tolerance to a wide array of processing conditions. Its low resistance to shear, high retrogradation, and poor freeze-thaw stability, limit the use of starch in industrial applications. These natural shortcomings can be overcome by different methods of modification. In recent decades, enzymatic modifications have been adopted, partly replacing the chemical and physical methods for the preparation of modified starch, as enzymes are safer and healthier than chemical method for both the environment and food consumers. Several enzymes viz., alfa-amylase, beta-amylase, glucose isomerase, pullulanase, xylanase, among others are use in modification of starch. The enzymatic modification of starch molecules directly affected properties of the modified starch especially in freeze-thaw stability of gels and retardation of retrogradation during storage. Combined enzymatic modification resulted in a marked increase in resistant starch and enzyme modified starch can be well utilized as a fat replacer. It is environment-friendly method and can provide desired functional characteristics.

The development of abrupt respiratory failure linked to fluid buildup in the lung's alveolar spaces due to an elevated heart-filling pressure is known as pulmonary oedema. Pulmonary oedema can result from any cardiac condition marked by a rise in left ventricular pressure. Long-term high capillary pressure can potentially break down the barrier, resulting in increased fluid transfer and permeability into the alveoli and atelectasis and oedema. Numerous variables, such as dysregulated inflammation, strong leukocyte infiltration, activation of procoagulant processes, cell death, and mechanical stress, contribute to the disruption of the alveolar-epithelial barrier. In order to properly treat patients with pulmonary oedema, a thorough medical history and a physical examination are necessary to assess the condition's symptoms and possible causes. In the interim, second-level diagnostic procedures such as echocardiography, chest radiograph, natriuretic peptide level, and pulmonary ultrasonography should be performed. To determine the best course of treatment for these patients, it is imperative to identify the unique pulmonary oedema phenotype. Early in the course of treating this illness, non-invasive ventilation should be taken into consideration. For pulmonary congestion, diuretics and vasodilators are employed. Vasopressors and inotropes are sometimes needed to address hypoperfusion. Additional strategies (i.e., beta-agonists and pentoxifylline) may be beneficial for patients with diuretic resistance and chronic symptoms. The pathogenesis, clinical manifestation, and therapy of pulmonary oedema are reviewed in this publication.

The illicit trafficking and abuse of narcotics targeting the younger generation has reached various corners of the region and the abuse is evenly distributed across all social strata of society. Basically, narcotics are very necessary and have benefits in the fields of health and science, however the use of narcotics becomes dangerous if misuse occurs. This research aims to analyze the weaknesses in the current Regulation on Cessation of Prosecution of Narcotics Abusers, to reconstruct the Regulation on Cessation of Prosecution of Narcotics Abusers Based on Restorative Justice Values. The approach method used in this legal research is a sociological juridical approach. The data obtained in this research was then selected and arranged systematically to be further analyzed and presented using qualitative analysis methods. The results of this research are that the weaknesses in the current regulations for stopping prosecution of narcotics abusers are weaknesses in terms of legal substance, weaknesses in terms of legal structure and weaknesses in terms of legal culture.

Mental health has become a critical global concern, with increasing awareness of mental illnesses and their profound impact on individuals, families, and communities. Saudi Arabia is experiencing rapid social and economic changes, with the Vision 2030 initiative aiming to enhance healthcare, including mental health services. Family physicians play a pivotal role in the healthcare landscape, acting as the first point of contact for patients seeking medical assistance. In Saudi Arabia, the integration of mental health services into primary care settings could revolutionize the approach to mental health, addressing the stigma associated with mental illnesses, minimizing the service gap, and delivering timely interventions. This review article aims to explore the current state of mental health services in Saudi Arabia and assess the role of family physicians in identifying and managing mental health conditions.

This article analyzes the behavior of the exchange rate and its volatility for the period from December 2, 2003, to November 2, 2023. The analysis conducted was of a quantitative documentary nature; the statistical tool EViews9 was used for data capture, analysis, and interpretation; therefore, it was not experimental. Data analysis was performed using the ARIMA model for exchange rate estimation and the ARCH and GARCH model families for conditional variance estimation – volatility. The results obtained allow observing the trajectory of volatility, whose behavior has been affected by the economic policy followed by the economic authority and the crises generated by subprime mortgages and the pandemic. It is recommended to incorporate other volatility models, as well as comparison with other key variables in the financial sector, particularly the price and quotation index of the Mexican Stock Exchange, to include more relevant information that can improve the behavior of the exchange rate and its volatility.

Unemployment has become an intractable underdevelopment phenomenon in all economies. Though most empirical studies asserts that unemployment is higher in less developed economies as compared to developed ones, it is an established fact that no country has the capacity to provide jobs for all its citizen simultaneously. Hence, the attainment or maintenance of an acceptable rate of unemployment is a major theme of public policy formulators. It is on this backdrop that this research is carried out. The paper aims at showing how government intervention in the agricultural sector was able to develop the sector within a very short interval in Rivers State, Nigeria and using content analysis, draws lessons therefrom for the developing countries for dealing with unemployment.

Background: Numerous malignancies, both benign and malignant is hosted by the sinonasal cavity that poses a diagnostic and therapeutic challenge to otolaryngologist and pathologists. One of the extremely rare neoplasm of the sinonasal cavity is secretory carcinoma (SC), previously called, mammary analogue secretory carcinoma (MASC). Majority of MASCs are localized to the parotid and salivary glands however, it is rarely documented in the sinonasal tract. Herein, we review the reported cases and report a twenty-one-year-old female patient presented to our ear, nose & throat outpatient department of tertiary care center as a polyp in the nasal cavity initially, which was excised on first diagnoses with normal histopathology (H/P). However, a year later she has a recurrence with an invasive course, followed by surgical exploration and confirmed as “Secretory Carcinoma” (SC) on histopathology, immunohistochemistry & genetic confirmation. At two-years follow-up, the patient has no clinical and radiological signs of recurrence. Aim: this review aims to outline the demographic, clinicopathologic, and confirmatory (radiologic, histopathologic, and immunohistochemistry) findings of the published cases. Methods: PubMed, Google Scholar, and MEDLINE search done with search words such as, secretary carcinoma, sinonasal tract, mammary analogue secretary carcinoma. Results: Total eight case including our case included in this review. The male/female ratio of occurrence of the SC of the sinonasal cavity was 3:5 (34.5:62.5%). Majority of the cases (7/8) reported in middle and old age group except one as reported in a 12 years old child. Equal case distribution among smoker ad non-smoker patients. The common symptoms were nasal obstruction, nasopharyngeal secretions, presence of mass, epistaxis and hyposmia. All cases were characterized by the presence of the ETV6-NTRK3 fusion transcript and / or rearrangement of ETV6 gene. Surgical excision with chemo/radiotherapy was the management considered in majority of the cases with good outcome. Almost all eight cases (100%) has no signs of recurrence both clinical and radiologically at a mean follow-up period of one year. Conclusion: Secretary carcinoma of the sinonasal tract is a new entity. More cases / studies are required to know the demographic, clinicopathologic nature, & prognosis of this newly emerging carcinoma.