Objectives: To offer a comprehensive review of the literature on Congenital heart block (CHB) in newborns born to women with systemic lupus erythematosus (SLE). Methods: A comprehensive computerized search of pertinent databases was conducted in order to find studies that satisfied the inclusion requirements. To find pertinent information, a thorough search of PubMed, SCOPUS, Science Direct, Cochrane and Web of Science was conducted. Results: Our data included eight trials with 23,967 women diagnosed with SLE. The prevalence of CHB in neonates born to mothers diagnosed with SLE ranged from 0% to 4.2% with a total prevalence of 41 (0.2%). Congenital and acquired heart conditions in children, such as structural and arrhythmic, are linked to maternal SLE. These adverse events were mainly associated with the disease activity. Anti-Ro/SSA antibodies have been related to both CHB and neonatal lupus through transplacental transfer. Conclusion: We demonstrated a low prevalence of CHD in neonates of mothers with SLE. However, the presence of maternal autoantibodies is the primary cause of neonatal CHB, which continues to be a serious pregnancy problem for moms with systemic lupus erythematosus. Although improvements in newborn care and prenatal monitoring have led to better results, problems still exist with early discovery, efficient treatment, and long-term follow-up.

The deflection of thin orthotropic rectangular plate under moving loads is a classic problem in solid mechanics. However, the equations are challenging to solve due to their non linearity and complexity. At the same time, this equation is a coupled fourth order partial differential equation having variables and singular coefficients. In this research article, the partial differential equation is converted to a set of coupled second order ordinary differential equations by using a special technique adopted by Shadnam et al., [19]. This transformed set of second order ordinary differential equations is then reduced using modified asymptotic method of Struble and Laplce transformation. The closed form solution is evaluated, resonance conditions are obtained and the results are showed in plotted curves to solve the variations in amplitudes for some varying orthotropic plate parameters with elastically supported ends under moving loads for both cases of moving distributed force and moving distributed mass.

The primary objective of this research is to study the Jordanian Cybercrime Law No. (17) of 2023 between regulating social media sites and restricting freedom of opinion. In addition, it clarifies the concept of cybercrimes and how to control social media sites while preserving citizens’ rights to freedom of expression. In terms of balancing digital security and controlling social media sites. Defining concepts and terms, such as “regulating” social media sites and “restricting freedom of opinion,” is crucial to understanding the law's impact on users. Monitoring and implementing the law by the competent authorities to avoid excessive violations of individuals’ rights. The researcher used the descriptive analytical method, as well as the inductive method, and the legal text analysis tool was used. This research has reached several results, the most important of which are that the Jordanian cybercrime law has used broad, vaguely defined, inaccurate, ambiguous, and non-specific terms, such as fake news. Even though these texts do not meet the requirements of international law regarding drafting legal texts precisely enough to allow individuals to regulate their behavior accordingly. In addition, the Jordanian cybercrime law focused on the penal and punitive dimensions and did not include any institutional or preventive measures to reduce negative phenomena in the digital environment. This research has reached several recommendations, the most important of which are that the Jordanian legislator must reconsider amending legal texts that are unfair to internet users in a way that leads to the adoption of balanced legal texts compatible with basic rights. These rights include the right to exchange information, the right to express opinions and ideas, and the right to privacy, which the Jordanian Constitution guarantees in Article (7).

This research article considers the flexural rigidity influence along both x and y axes on the dynamic response of orthotropic rectangular plate resting on constant elastic foundation with elastic end conditions. The orthotropic rectangular plate model is a coupled fourth order partial differential equation having variables and singular coefficients. The solutions to this model are arrived at by reconstructing the fourth order partial differential. This partial differential equation model is converted to a set of coupled second order ordinary differential equations by using a special technique adopted by Shadnam et al., [11]. This set of second order ordinary differential equations is then reduced using modified asymptotic method of Struble. The closed form solution is evaluated, resonance conditions are obtained and the results are showed in plotted curves to depict the influence of flexural rigidities along both x and y axes on the dynamic response of orthotropic rectangular plate resting on constant elastic foundation with elastic end conditions for both cases of moving distributed mass and moving distributed force.

Background: Viral conjunctivitis is a prevalent eye infection that is typically linked to epidemic circumstances. The aim of this study was to evaluate the clinical features of continuing viral conjunctivitis in Sudan during times of conflict. Methodology: This is a prospective descriptive study that was launched after seeing an uncommon presentation of acute hemorrhagic conjunctivitis in people of all ages around the beginning of August 2024. Results: Subconjunctival hemorrhage (SCH) was observed in a total of 83 cases, with 76% being males and 95% being females. Swelling of the eyelids was observed in 82 patients, with 82.5% being males and 81% being females. Conjunctival edema was observed in a total of 79 patients, with 77.7% being males and 81% being females. The majority of the patients exhibited symptoms in both eyes, while 8% and 4% experienced symptoms in the left eye and right eye, respectively. Conclusion: This pandemic of viral conjunctivitis, which often begins in one eye and spreads to the other, can clear itself in a week or two, based on the typical clinical symptoms. Steroids and antibiotics work synergistically to alleviate symptoms and avoid bacterial infections.

Curriculum based ideological and political education is a new requirement for talent cultivation in universities in the new era of education reform. It includes diversified curriculum based ideological and political education elements such as norms, culture, and competition in traditional ethnic sports, and is the main path to achieve the fundamental task of cultivating morality and talents. On the basis of exploring the effectiveness of traditional ethnic sports teaching in undergraduate colleges under the background of curriculum ideological and political education, this article analyzes how to carry out traditional ethnic sports teaching in undergraduate colleges under the background of curriculum ideological and political education, and give full play to the educational value of traditional ethnic sports.

Strategic administrative initiatives in schools helps in identifying emerging trends and anticipate future challenges, allowing them to prepare and respond proactively so as to bring change in students’ academic performance. For three consecutive years (2016 -2018), Kisii County’s mean standard score in Kenya Certificate of Secondary Education declined resulting to an average mean standard score of 3.765 (D+) which was still below the National Mean Standard Score of 3.962. The purpose of this study was to determine the extent to which strategic administrative initiatives influence academic performance. Education Production Function theory was applied. The study employed a descriptive survey design. Target population of 353 principals and 4354 teachers were considered from 353 public secondary schools in Kisii County. Slovin’s formula with a margin error of 0.05 was used to sample 28 principals and 341 teachers as respondents. Stratified random sampling was used to get school categories. Instruments for this research included: questionnaire for teachers and interview schedule for principals. Validity of research instruments was ascertained by supervisors’ inputs from the School of Education Kisii University. Questionnaires were considered reliable since Cronbach’s Coefficient Alpha 0.998 obtained was higher than the critical Cronbach alpha of 0.7 on a scale of -1 to +1 by use of test re-test method. Data was analysed both qualitatively and quantitatively. Qualitative data on interview schedules were organized based on research objective and themes of study. Data was presented using percentages, means, frequency distribution tables and bar graphs for easier interpretation. This study’s findings were: The strategic administrative initiatives have a positive influence on academic performance. This study is significant as it indicates that county and sub-county secondary schools need to improve on the application of the strategic administrative initiatives in the academic activities/programs for them to do better academically. In conclusion, National and Extra- County secondary schools’ strategic administrative initiatives have a high positive influence on academic performance compared to county and sub-county secondary schools.

Tamsulosin HCl is an αq-1 adrenergic receptor antagonist that is primarily used to treat benign prostatic hyperplasia (BPH), a disease defined by an enlarged prostate. The aim of this project is to develop, analyze, and compare the developed formulations to the innovator product (Flomax). The formulations were prepared by integrating Eudragit L100-55 as enteric polymers in various formulations, Drug coat L30D as a sustained release coating polymer, and PEG 6000 as pore forming in distinct quantities. The formulation F8 exhibited %CDR of 98.8%, comparable to the Flomax (innovator product) and the similarity factor (f2) was calculated and found to be 94.3% marking this formulation equivalent to the innovate product. The improved formulation was tested for stability for the 1st month at 40 ± 2°C and 75 ± 5% R_H, as per ICH guidelines. The regression results of the improved formulation led to an inference that F8 indicates first-order kinetics with an estimated regression value of 0.926, and it was concluded that the drug had been released through diffusion mechanism.

This study investigates the concept and strategic significance of economic corridors, particularly focusing on India’s initiatives in Eurasia, including the International North-South Transport Corridor (INSTC) and Chabahar Port. The primary objective is to analyze how economic corridors serve as instruments for enhancing regional integration, economic growth, and geopolitical influence. Drawing from historical trade routes like the Silk Road, the research explores how modern corridors have evolved into critical drivers of global connectivity. The methodology employed includes a systematic review of academic literature, policy reports, and case studies on various economic corridors, with a particular emphasis on India's projects. The research further evaluates the infrastructure, trade facilitation, investment zones, and institutional cooperation involved in these corridors. The study also assesses social and environmental considerations, alongside an examination of ongoing developments in key Indian initiatives. The findings highlight the potential of economic corridors to significantly improve regional trade and integration, with the INSTC and Chabahar Port offering India strategic advantages in accessing new markets and counterbalancing regional competitors. However, the study also identifies challenges, including infrastructure bottlenecks, geopolitical tensions, and the impact of international sanctions, which may hinder the full realization of these corridors' potential.

Background: Surgical advancements have led to the development of Enhanced Recovery After Surgery (ERAS) guidelines. This study aims to assess the nurse’s role in improving patient outcomes and healthcare efficiency using ERAS. Methodology: This cross-sectional study was conducted in Aster Sanad Hospital Riyadh, Saudi Arabia. Data were collected using a self-administered questionnaire and from electronic medical records. The study sample was given a self-administered questionnaire. Data were analyzed using the Statistical Package for Social Sciences (SPSS), version 21 (IBM SPSS Statistics, Armonk, NY) to analyze the data. Result: The result shows that there is a significant level of confidence among a notable portion of respondents regarding their understanding of ERAS protocols, there are also areas of uncertainty and variability, indicating the need for targeted interventions to enhance comprehension and implementation. Moreover, there is widespread acknowledgement of the pivotal role of nurses in ERAS implementation, yet significant proportions express reservations about nurses' training, workload constraints, and support from healthcare institutions. Conclusion: Overall, these findings emphasize the multifaceted nature of ERAS implementation, requiring a comprehensive approach that addresses training, communication, workload, and resource allocation to optimize patient outcomes and healthcare efficiency in Cesarean surgery units at Aster Sanad Hospital.

Breast cancer has become the leading cause of cancer-related death among women, partly due to therapeutic resistance and treatment-related complications. Chemotherapy and hormone therapy play a crucial role in managing breast cancer patients, providing essential treatment for both disease control and overall survival. However, as new therapeutic approaches are introduced and life expectancy continues to increase, the use of these treatments has been associated with persistent adverse effects, including dyslipidemia. This article presents the case of a breast cancer patient treated with chemotherapy and tamoxifen-based hormone therapy who developed severe mixed dyslipidemia. It also reviews lipid metabolism alterations observed in breast cancer patients, emphasizing the importance of monitoring lipid levels in these patients, particularly those undergoing hormone therapy or chemotherapy, to prevent cardiovascular complications.

This study examined language use of the exogamous families in Southwestern Nigeria in order to find out the language choice in a range of domains (formal and non-formal) and with different speech partners. The theoretical framework adopted for this study is Fishman’s (1972) Domain Analysis. Language use questionnaire was structured and administered to these families. The population of the study included nine hundred (900) respondents drawn from twelve (12) Local Governments of South-western Nigeria and the respondents were strictly from exogamous families. Data collected were analysed using statistical tool. The findings revealed that English language is the most used language among the exogamous marriage families in South-Western Nigeria in both formal and non-formal domains. The study also revealed that the children of all the exogamous marriage families have language socialization as they acquired at least one of the languages spoken by their parents easily, but lack the use of it in everyday dialogue rather they prefer to use English. This is because, they lack balance bilingualism or 'multilingualism. The researchers recommended that comparable research could be conducted on exogamous couples living in both rural and urban communities in order to enrich the knowledge of the sociolinguistic findings and better assessment.

release of greenhouse gases linked to the manufacture of cement. Geopolymer as a binder for making concrete consists of two (2) main components; (1) the alkaline liquid consisting of sodium or potassium silicate and sodium or potassium hydroxide and (2) source material of geological origin or by-products rich in silica and alumina. The combination proportions utilised in this investigation were formulated utilising Scheffe's (5,2) basic lattice mix design approach with the intent to create the trial mix and the control mix. A total of thirty (30) geopolymers concrete sample mixes were made in the laboratory, with fifteen samples for trial mixes and fifteen mixtures for control mixes. These mixtures were used to appraise the performance of the sawdust ash geopolymer concrete in term of its flexural strength property. The study used sawdust ash as the source material and investigation revealed that subjecting sawdust ash to pyrolysis without oxygen has a notable impact on the pozzolanic characteristics of the constituent. Consequently, this also affects the flexural qualities of the concrete. Furthermore, it has been shown that softwood sawdust exhibits superior pozzolanic properties when compared to hardwood sawdust. The study revealed that the optimum flexural strength of sawdust ash blended geopolymer concrete is 3.3002 MPa and the corresponding mix deign obtained. Computer programs were created using Matlab and used for the optimization and prediction of the flexural strength of sawdust ash based geopolymer concrete.

The study of the apical bases has been relevant in orthodontics for many decades; its study was carried out both on jaw models and on lateral cephalograms. Dentistry today is impossible without three-dimensional studies, which allows you to study an object from any angle and visualize the smallest changes in the anatomical structures of the area under study. The use of cone beam computed tomography to study the apical bases of the jaws makes it possible to study the configuration, size, and position of both the bases themselves and the structures that form them. The parameters we proposed allow us to study the width, length and angle of inclination of the apical base on single CBCT sections. Clinical use of the proposed analysis will contribute to more complete and accurate orthodontic treatment planning.

This study analyses the Government's responsibilities in implementing land acquisition in National Strategic Projects. This is qualitative research using a statutory approach, case and conceptual approaches. The primary legal materials resulted from relevant laws and legislation. The legal material collected is analysed prescriptively. The results showed that national strategic projects' land acquisition planning arrangements must be accommodated adequately and comprehensively. There are no land acquisition planning arrangements that accommodate justice, which has encouraged the creation of land acquisition conflicts. Research findings show that the Government's responsibility in acquiring land for National Strategic Projects is weak, and regulatory arrangements are unclear. Government responsibility still needs to be stronger and have strict legal regulations. Legal certainty for economic interests in National Strategic Projects is more dominant. At the same time, the Government has ignored the interests of law and justice for the affected communities.