A novel family of macrocyclic complexes with tetra aza macro cyclic ligand and (X=Cl- , NO3-) have been synthesized and characterized by elemental analysis, IR, electronic, and EPR spectral studies. The molar conductance measurements of the complex in Dimethyl sulphoxide (DMSO)/dimethyl form amide corresponds to non-electrolytes for all the Mn(II) complexes except the complex with ligand LA which are 1:2 electrolyte. The spectra are consistent with the formula [MnLx2] and [Mn (LA) (H2O) 2] X2 and distorted octahedral geometry. The biological activity of these complexes was evaluated against different species of bacteria and plant pathogenic fungi and compared with different ligands.

Meditation produces various effects on human physiology, which are mediated via autonomic nervous system. Meditation is a simple and scientific technique to elicit physical and mental relaxation response, to change one’s attitude and transform life-style. Regular practice of it brings transformation in overall wellbeing of person. The cardiovascular morbidity is increasing in India in recent years. The present study was done to know the effect of meditation on heart rate and blood pressure in healthy volunteers above the age of 35 years. The cardiovascular status of the subjects was assessed clinically in terms of resting heart rate and blood pressure before the start of meditation practice and again after 4 months of practice of meditation. The results were compared and analysed.. From the study it was observed that significant reduction in the heart rate occurs in the subjects practicing meditation (P < 0.001). The systolic blood pressure was lowered to a highly significant level (P < 0.001). The diastolic blood pressure was reduced significantly (P < 0.001). This shows that the yoga provides significant improvement in ageing to reduce the morbidity and mortality from cardiovascular diseases. Meditation provides significant improvements in physiological cardiovascular functions by tilting of autonomic balance from sympathetic in favour of parasympathetic.

The objective of this study is twofold: first, determining methods for setting parameters which describe thyroid gland responses at the initial stages of a given iodine-131 metabolic radiotherapy, and second, predicting treatment outcome. Radioactivity measurements were taken on patients suffering from hyperthyroidism. Two physicochemical parameters were analyzed and studied: iodine-131 thyroidal uptake and effective half-life. We thus achieved a much higher rate of success with minimal reverse results. The effective half-life, combined with thyroidal uptake, led to better predictions of success or failure for a given treatment. These set procedures allowed us to describe beforehand thyroid gland responses to metabolic radiotherapy as compared to the conventional methods exacting periods of more than six months.

The study was conducted on Haryanvi 800 adults comprising of 400 males and 400 females. Measurements were taken using standard anthropometric instruments.i.e. varnier calliper and anthropometric rod. The purpose of study was to access the bizygomatic diameter and stature and to find out the correlation between them. The data were then analysed by statistical software. The mean bizygomatic diameter for male and female were 13.08 and 12.35 respectively. The mean stature was 168.71 in male and 155.18 in female. Both the measurements were more in males then females. The results showed a statistically significant correlation between bizygomatic diameter and stature in both sexes.

There has been an exponential increase in the number of countries that have adopted offset policies as a means to develop a capable, ready and cost-effective aerospace industry. Offset transactions generates billions of dollars annually, prompting aerospace companies to increase their compliance systems and economic models (Jurgen and Paul, 2004). This purchasing and sales arrangement is used by numerous governments around the world to negotiate high-tech public procurement contracts and has also been adopted by most private organizations. This research noted that for private businesses, offsets are instrumental in establishing global development capabilities and access to emerging markets. For buyers, especially in emerging countries, offsets are a way to accelerate industry and businesses development. The main purpose of this study is to critically analyze the role of offsets and offset management within the aerospace industry. The study conducted thirteen (13) interviews with Offset Managers from most of the prominent firms in the prime contractor and supplier ranks. The key findings of this study indicate that prime contractors view offsets as a major issue for their firms but the majority of supplier companies do not have this view. Results show that offsets organizational structures follow a decentralized, narrow, and functional focus. Offset satisfying activities are well aligned to achieve the goals of the foreign governments that procure aerospace products. The study pointed out that suppliers are not fully engaged in the aerospace industry offset process. It also identified opportunities for improving offset practices in the aerospace industry. The study enhances insight into understanding buyer and seller alignment on the business and strategy; a long-term approach to the relationship; good communication and transparency; and having a single government agency responsible for offsets in order to avoid confusion, corrupt practices, and conflicting demands.

A blood pressure has caused a lot adverse effect to the body and as a whole society if it remains untreated. Hypertensive state causes increase in left ventricular diameter as well as mass. These two conditions can be also called as LV hypertrophy. Method: 60 male individuals aged from 35 to 45 years enrolled in the study from Dhiraj general hospital after getting ethical approval. Their general examination and history was taken after that blood pressure was recorded. Participants were divided in 4 groups based on JNC guideline. 2 D echocardiography was performed and Left ventricular mass (LVM) recorded. Left ventricular mass index (LVMI) was calculated after getting body surface area (BSA). Result: Blood pressure changes show marked variation in Left ventricular mass as well as Left ventricular mass index. Pre hypertensive and hypertensive stage 1 and stage 2 shows marked rise in LVM in comparison with normotensive individuals. Blood pressure is positively correlated with left ventricular mass and also with ventricular mass index. Out of all 4 groups Prehypertensive stage shows more risk for LVM and LVMI. Conclusion: There is multifold rise in LVM and LVMI when blood pressure increased from normal range. The left ventricular hypertrophy has one independent factor above other confounding factors.

This study was conducted to determine the association of Insertion-deletion Polymorphism in the Angiotensin-Converting Enzyme (ACE) Gene and Human Essential Hypertension among Sudanese in Al Nubba Village. A case-control community-based study was performed, Blood samples were collected from 54 subjects in a rural area around Khartoum (Al Nubba Village). The frequencies of the insertion (*I) and deletion (*D) alleles of the ACE gene were investigated, Polymerase chain reaction (PCR) was detected for the Insertion/Deletion polymorphism. Allele frequencies were calculated, our data indicated a preponderance of the *D allele among the Sudanese population. The percentage of Case/Control for Homozygous deletion DD, Homozygous insertion II and Heterozygous DI are almost the same. Further studies are recommended with a large sample size

This study represents correlation of five needle aspiration cytology with histopathology at the cytology department of khanpur Kalan Medical college during 3 year period only the cases where subsequent histology diagnosis was available were analyzed. All the aspirations were performed by the pathologists. Out of the total of the 89 cases cytological diagnosis was malignant in 35 cases (39.32%). Two cases were false negative. There were no false positive case in the study. A sensitivity Rate of 94.5% and specificity of rate 100% was obtained for malignancy. Positive and negative predictive value for the diagnosis of malignancy was 100% and 94.7% respectively. accuracy of the test was 97.26%. FNA specific diagnosis showed an overall agreement of 98.5% for malignant lesions. All these result compare favorably with the best reported in literature. All these factors help the clinicians in the management of malignant breast lesions.

This study sought to determine the effect of senior secondary school students’ prior knowledge of instructional objectives on their achievement in chemistry. Three research questions and three null hypotheses guided the study. The design employed was a pretest posttest experimental design. The population was four thousand six hundred and ninety-three (4393) SS2 students who were offering chemistry in all the secondary schools in Awgu Educational Zone. Chemistry achievement test (CAT) developed by the researcher was used to collect relevant data from a sample of 184 senior sec. students selected from single sex schools in Awgu Educational Zone. The CAT was face and content validated by experts in educational measurement and evaluation and chemistry education. Reliability coefficient of 0.80 was obtained for CAT using Kuder Richardson formula -20. Mean and standard deviation scores were used to test the three null hypotheses at an alpha level of 0.05. the study revealed that students taught with prior knowledge of instructional objectives (experimental group or Wipkoiob) achieved better results than students taught without prior knowledge of instructional objective (control group or Wopkoiob) and males achieved better than the females. There is no significant interaction of gender and strategy on students’ chemistry mean achievement. The researcher therefore recommended that chemistry teachers in Nigeria should present instructional objectives in their lesson plans to their students ahead of instruction.

Helicobacter pylori infection is a widespread problem all over the world. It is the major cause of peptic ulcer disease and gastric carcinomas. Among the various methods available in clinical practice are histopathology, rapid urease test (RUT), cultureand PCR carried on gastric biopsy samples.Non-invasive diagnostics like stool antigen detection are available for rapid diagnosis and treatment follow up. The purpose of the study was to validate antigen detection of H.pylori from stool specimen and also to compare the test with that of rapid urease test and histopathology. This cross sectional case study was conducted on 260 subjects with symptoms of acid peptic disease who underwent endoscopic examination and not on non steroidal anti-inflammatory drugs or proton pump inhibitors. Gastric biopsy specimen and the stool samples were collected from patients with mucosal changes. Biopsy sample was subjected for Histopathological examination and Rapid urease test. Stool Antigen detection test was performed by immunochromatography method. Among the 260 study subjects stool antigen detection was positive in 184(70.7%) of the study population. H.pylori was detected by Rapid Urease test in 225(86.5%) of the patients while Histopathological examination identified H.pylori in 230(88.46%) by Haematoxylin and Eosin (H&E) staining and 235(90.38%) by Giemsa staining respectively. The sensitivity, Specificity, Positive predictive value and negative predictive value of Stool antigen detection when compared to Biopsy results were 78.29%, 100%, 100% and 32.89% respectively. The non invasive tests like stool antigen tests for H.pylori could be used as a routine diagnostic tool in the microbiology laboratory. The lower sensitivity of the stool antigen detection in comparison to histopathology and RUT is the drawback that has to be overcome.

Phosphoric acid etching is the gold standard method of enamel preparation before application of bonding resins for orthodontic brackets. With the recent introduction of erbium-doped yttrium aluminum garnet (Er:YAG) laser in dentistry for the ablation of hard tissues, including enamel and dentin, laser enamel preparation has been proposed as an alternative to phosphoric acid etching. Hence this study was conducted to evaluate the shear bond strength of bracket bonded to teeth etched by Acid, Er:YAG laser. The aim of the study is to “Compare the bond strengths of orthodontic bracket etched by acid, Er: YAG laser, and combined treatment on the enamel surface.” The objective of the study was to investigate methods that could obtain the maximal bond strength and to analyze the fracture mode of each method

Introduction: Abnormal uterine bleeding is the most common presentation amongst women of all age groups attending the gynecology OPD. The etiology of AUB varies depending on the age group. Histopathological study of endometrial biopsies by light microscope is considered the gold standard for diagnosing the endometrial pathology of AUB. Aims & Objective: The aims and objective of this study is to determine histopathological patterns seen in endometrial biopsies of women who presented with AUB. Material and methods: The study was carried out in the Department of Pathology in Government Medical College Haldwani from January 2008 to January 2018. Biopsy sections underwent proper processing and stained with hematoxylin and eosin and were observed under microscope. Relevant patient details were collected from departmental records. Result: Total of 505 specimens of endometrial biopsies were studied. Maximum (47%) patients were between 36-45 years. Commonest pathology was disordered proliferative phase (20%). 11% showed hormone related changes. Hyperplasia was observed in 7%. Endometrial polyps were seen in 2%, Endometritis was found in 2% which included 2 cases of tubercular pathology. Endometrial carcinoma was seen in 2%. Conclusion: Maximum patients in our study belonged to the perimenopausal age group. Disordered proliferative pattern was the most common pathology observed. Endometrial carcinoma was seen only in post menopausal women. Endometrial biopsy proved to be an effective tool in histopathological characterization of endometrium and can be helpful in avoiding hysterectomy in AUB.

The aim of this study is to determine what factors make banking companies doing earnings management in Indonesia. Based on previous research, we identify some factors can make the company doing earnings management such as tax avoidance, leverage, company size and corporate governance components for example IO (Institutional Ownership), BOC (Board of commissioner), IC (independent commissioner). The research proved that the banking companies in Indonesia applies corporate governance to improve the quality of financial statement and avoid earnings management. These results also showed that tax avoidance, leverage, size company has no significant effect on earnings management.

Cervical cancer is the fourth most common type of cancer in women worldwide with 85% of cases occurring in developing countries. Endocervical adenocarcinoma is ten times less frequent than squamous cell carcinoma; the most recent literature indicates an increase of three to four times in its incidence over the last few years. The main objective of reporting present case is to draw attention of an unusual presentation of chondroid metaplasia in endocervical adenocarcinoma in a 73 year old post menopausal woman because it is important to recognize the non‑ neoplastic nature of this condition and to differentiate it from malignant counterpart of the tumor. Hence, a careful clinical and histopathological examination is required to avoid the misinterpretation of non‑ tumor cartilaginous foci as a component of malignant neoplasm.

A total of two hundred ears of CSOM cases in different age groups & sexes were subjected to bacteriological and clinical studies in the Department of Microbiology & ENT, Patna Medical College & Hospital. The ears were further subdivided into group I where ear swabs were studies for aerobic organisms and cultural & sensitivity pattern. In group II 50 swabs were studies for anaerobic organisms and culture and sensitivity pattern. The commonest organisms isolated in group I were Staphylococcus aureus followed by Pseudomonas aeruginosa while pepto-streptococci species were found in group II. Ciprofloxacin was found to be the drug of choice for most of the organisms followed by Norfloxacin,cefexime Cefoperazone & Gentamycin