This study was done to estimate the serum uric acid level pre and post dialysis. To do this 50 patients with chronic renal failure and 50 apparently health individual as control group were involved. Uric acid level was determined for all patients and control group and the result was analyzed using spss package. The mean of serum uric acid pre dialysis is significantly raised compare with that of the control group (9.4±2.2 versus 3.7±0.8). The mean of uric acid post dialysis is significantly decreased compared with that of before dialysis (9.4±2.2 versus 2.7±1.2) and P.value 0.00. The sex frequency for pt with CRF (43.3% female and 56.7% male). The correlation between duration of disease and Serum uric acid significant negative correlation and the (P.value =0.01 r = - 0.40).

This study was done to estimate the serum uric acid, phosphate and calcium level pre and post dialysis. To do these 50 patients with chronic renal failure and 20 apparently healthy individuals as control group were involved. Uric acid, calcium and phosphate level was determined for all patients and the control group and the result was analyzed using spss package. The mean of uric acid pre dialysis is significantly raised compared with that of the control group (9.4± 2.3 versus 3.9±0.9) mg/dl. And the mean of uric acid level post dialysis decreased after dialysis compared with that of before dialysis (2.9± 1.3versus 9.4±2.3) mg/dl and P.value 0.00. The mean of calcium pre dialysis is significantly decreased compared with that of the control group (5.4± 0.85 versus 9.8±0.8) mg/dl. And the mean of calcium level post dialysis decreased after dialysis compared with that of before dialysis (4.4±1.07 versus 5.4± 0.85) mg/dl. The mean of phosphate pre dialysis is significantly raised compared with that of the control group (5.7± 2.04 versus 3.7±0.46) mg/dl. And the mean of phosphate level post dialysis decreased after dialysis compared with that of before dialysis (3.1± 1.3versus 5.7±2.04) mg/dl and P.value 0.00. In the test group, serum uric acid, phosphate and calcium were no correlated with the duration of the disease.

Background: The hemostatic alterations play an important role in malaria pathogenesis and in the progression of disease. In severe infection the accelerated coagulation cascade activity with accelerated fibrinogen turnover increase the bleeding tendency and may lead to DIC. Objectives: This study was aimed to determine the Alteration of coagulation parameters in Plasmodium Falciparum malaria Patients and its correlation with degree of parasitemia in Khartoum state. Sudan; 2019. Material and method: Analytical cross sectional study, 170 blood samples were enrolled in this study.85 samples of blood were collected from patients with falciparum malaria and 85 samples were collected from healthy individual as control, then PT and APTT will be measured by coagulometer. Result: The mean of PT was significantly high in case than in control (14.201second vs 13.668 second, (P value (< 0.01)).While there was no differences in the mean of APTT between case and control (33.075 vs 33.192 second ) P value (0.735). Conclusions: Our study concluded that the mean of PT was significantly higher in case than control, While there was no differences in the mean of APTT between case and control, and There was no differences between the PT and APTT of case and control according to gender. And there is no correlation between degree of parasitemia in PT, APTT and age.

This article argues that the current National Policy on Education of the Federal Republic of Nigeria has its roots in the educational philosophies of the ancient philosophers. The article states, discusses and traces the three major ideas and the development of educational Philosophies of the ancient Philosophers, namely Socrates, Plato and Aristotle. The article further discusses how their ideas has shaped or influenced subsequent philosophers of Education as postulated by John Dewey, John Milton, Gregory and Abraham Maslow. In application the paper concludes by comparing and contrasting the National Policy on Education of the Federal Republic of Nigeria with the above schools of thought.

Tourist interest in heritage and historic tourism site has been expanding and important nowadays. The declaration of Melaka as a World Heritage Site by UNESCO in July 2008 has made it one of the major tourist destination in Malaysia. This declaration has boosted the arrival of tourist not only from international tourists but domestic tourist too. The objective of this study are to find out about the knowledge of domestic tourist towards Melaka’s historical background, attitude towards the preservation and conservation and tourist practice during visiting the heritage and historical site around Melaka city. A total of 263 respondents from domestic tourists travelling in Melaka were involved in this study. Result show that knowledge of historical background and attitude toward the preservation and conservation of tourist site is high. However, tourist practices to visit heritage site and historical site are relatively low especially for tourists visiting museums.

Various researchers have discussed about the styles of leaderships and their ways of communication within the organization among various levels of professionals. This study intent to define the successful style of leadership that is suitable for educational institutions and the type of communication required for the success of the Higher Education institutions. Education though not a business is very competitive today. If there is no proper communication among the three levels of the Management, the success of the institution is debatable. The paper aims to design the dimensions of communication starting with the Top level - Principal/College head, Middle Level - Department head/Chairperson and Bottom level - Faculty members (Professors/Associate Professors/Assistant Professors/Lecturers). Though there are many people above in the Management like CEO/GM/Correspondent and End receivers’ who are the most important stakeholders: Students. But the study focuses only on above mentioned 3 levels as there is huge need to communicate most of the time, among themselves as a team. This study is has identified these three levels of employees in educational institutions as Scholars, who directly contribute to the success of the institution. The objective of the study is to develop suitable leadership style and communication system that can develop trust among the scholars. It is essential for institutions that are evolving and changing for various reasons such as Vision 2030, Accreditation, Competitiveness and achieving global standards.

Fibroadenoma of breast is very common in females, but a rarity in males. Gynecomastia and pseudogynecomastia is a common presentation. A case of fibroadenoma with concurrent gynecomastia in a young male is presented below.

The association of celiac disease and idiopathic portal hypertension is a rare entity whose etiopathogenic mechanism has not yet been elucidated. We report two cases of celiac disease associated with idiopathic portal hypertension. In both cases celiac disease diagnosis was made based on the positivity of anti-tissue transglutaminase IgA and villous atrophy on the pathological study of duodenal biopsies. Idiopathic portal hypertension was retained after complete biological, radiological and endoscopic assessment excluding all possible causes that can manifest as portal hypertension. Both patients improved after gluten-free diet.

Objectives: To assess the routine laboratory analytes, serum Thyroid Stimulating Hormone (TSH), Lactate Dehydrogenase (LDH) and Uric acid in women with preeclampsia compared to normotensive healthy pregnant women and to determine the concentration of liver enzymes in women with preeclampsia. Materials and Methods: The study was carried out in the Department of Biochemistry of MVJ Medical College and Research Hospital. Thirty women with preeclampsia and thirty normotensive pregnant women admitted to the Department of OBG were recruited for the study. Blood samples were collected and analysed for serum TSH, LDH, uric acid and liver enzymes. Mann Whitney U test was employed to evaluate the significance of the differences obtained between the groups. Results: All three analytes were significantly higher in the case group when compared to controls. LDH and ALT (Alanine transaminase) showed significant difference even within the mild and severe preeclampsia groups. A moderate positive statistically significant correlation (r=0.348, p=0.006) was obtained between serum TSH and LDH. Serum TSH level showed a sensitivity of 66.64%, specificity of 73.33% and a positive predictive value of 71.4%. A De Ritis ratio of 1.82 was observed in preeclampsia. Conclusion: TSH, LDH and Uric acid showed significant elevation in preeclampsia. TSH and LDH levels showed a positive correlation. Hence, TSH, LDH and Uric acid could serve as markers of preeclampsia. A hypothyroid status in early pregnancy might be seen as a risk factor for preeclampsia. An elevated ALT and a high De Ritis might indicate an underlying liver and cardiac compromise in preeclampsia.

Provides reliable contact information about patient care and safety. Analysis of the lack of reports between hospital and emergency room personnel indicates incomplete or lack of general information. Nurses play an important role in dissemination and dissemination of information by using nurse directives. Sharing information in a hospital affects patient safety and treatment plans and delivery based on this information. Test modifications that were used for the comfort of patients entering the ambulance for several days decided to participate in this study. Sample size should take into account sales that occur evenly throughout the month, with each change and day of the week. Documenting the content of the reports submitted will affect breastfeeding practices. You can also use the standard login format and technology to improve content delivery.

In order to obtain the optimal extraction conditions of anthocyanin in purple eggplant peel, purple eggplant peel was used as experimental material, the single factor test conditions were screened through determinating the content of anthocyanin in the crude extraction solution. The optimum range of the concentration of ethanol, the ratio of liquid and material ratio, the time of extraction, and the temperature of extraction were determined. Then the quadratic regression orthogonal rotation combination design was used to optimize the extraction process of anthocyanin. Four factors and regression model of content of anthocyanin were obtained. The results showed that the factors affecting the extraction efficiency of anthocyanins were as follows: the concentration of ethanol > the temperature of extraction > the ratio of liquid and material ratio > the time of extraction. Finally, the optimum extraction conditions of anthocyanin extracted from purple eggplant peel were obtained as follows: the concentration of ethanol was 78.6%, the ratio of liquid and material ratio was 60:1 (mL g-1), the temperature of extraction was 20 ℃, the time of extraction was 150 min, and the content of anthocyanin was up to 4.2399 (mg g-1). The crude extracting solution of anthocyanin was clear and stable, and the color of stable extracting solution was dark red. The validation experiment was carried out at the optimized conditions, and the preferable results were obtained, which showed that the optimization of extraction technology of anthocyanin in purple eggplant peel by this method was reliable, and which had practical guiding significance.

Valvular heart diseases affects millions of patients worldwide, and the burden is rising as the population ages. Severe valvular heart disease is associated with significant morbidity and mortality, claiming over 50,000 lives annually in the USA [1]. Coumadin (generic name: warfarin) is an anticoagulant, which stops the formation of blood clots and makes blood thinner (less viscous). As for Vitamin K, it helps the process of blood clotting. In other words, warfarin has the opposite effect to Vitamin K. Warfarin is a widely used and cheap drug which decreases the risk of thrombosis or embolism in patients with diseases such as atrial fibrillation (AF), venous thrombo-embolism, and mechanical heart valve surgeries. Treatment with warfarin requires close monitoring with regular tests of PT-INR for better outcome of patients [2]. The purpose of the study is to shorten and simplify the process for the testing and prescription of warfarin by introducing point of care analysis (POC). The aim was also to evaluate changes in time and cost related to the new processes. Effective management of warfarin therapy is frequently challenged by its difficult pharmacology and adverse effects. One strategy to ensure safe warfarin use is provision of comprehensive warfarin education to patients regarding self-testing and self-management of accurate dose according to INR value. Point of care INR monitoring has shown beneficial impacts on the risk of thromboembolic events, anticoagulation control, patient satisfaction, and quality of life [3].

This research is to test the influence of professional commitment and locus of control on whistleblowing intensity through ethical sensitivity at Public Accounting Firms in Makassar. Data was obtained from 4 Public Accounting Firms in Makassar. Primary data was obtained through field research by distributing questionnaire/statement sheet to 31 respondents. Data analysis method was path analysis processed by SPSS-21 program. The research results show that professional commitment and locus of control have partial positive and significant effects on the ethical sensitivity. In addition, professional commitment has positive and significant effects on whistleblowing intensity, locus of control has positive yet insignificant effects on whistleblowing intensity, and ethical sensitivity has positive and significant effects on whistleblowing intensity. Meanwhile on the intervening variable, professional commitment and locus of control have partial effects on whistleblowing intensity through ethical sensitivity.

A medico-legal autopsy on an adult if performed completely and systematicall, with a reasonable uniformity and clarity can help in the betterment of outcomes while providing justice. The pre-requisites prior to an autopsy, and a thorough external examination are very important before moving on with the internal examination. In many situations a proper external examination will be sufficient to give a medico-legal report; if done methodically. There are four types of skin incisions employed in a medico-legal autopsy to examine three body cavities. The internal examination can be done using four dissection techniques as outlined in the existing literature. Examination of brain, heart, neck structures, spinal column and genitalia are very important and requires an organized approach in order to not to miss salient findings. Finally, while closure of the cadaver the doctors must bear a very important fact in mind that the body on the table was once housed by a living being and hence s/he must be treated with the same respect and dignity as one would expect him/herself to be treated by others.

The study examined the impact of working capital management on the profitability of Pharmaceutical firms listed on the Nigerian Stock Exchange market. Correlation and ex-post facto research design were used in a sample of 5 Pharmaceutical firms. Secondary data for a period of 5 years (2013-2018) was used, and Ordinary Least Squares (OLS) multiple regression was employed in data analysis. The study found that working capital management (account receivables collection management, accounts payables management, inventory management, cash conversion cycle management, operating cash flow management) has a significant impact on the profitability of listed pharmaceutical firms in Nigeria. It is therefore recommended among others that managers should focus on reducing inventory days, collect receivable as soon as possible because it is better to received inflows sooner than later, and delay payment of creditors in order to invest the money in short-term securities which are profitable. Also, the cash conversion cycle should be elongated to the extent that it maximizes profit.