ORIGINAL RESEARCH ARTICLE | Nov. 28, 2019
Reconnaissance Geochemical Exploration in Kaiama, North Central, Nigeria
Alepa VC, Bale RB, Alimi SA, Bonde DS
Page no 457-472 |
10.36348/sjeat.2019.v04i11.003
Reconnaissance exploration for ore mineralization in Kaiama and environ have been carried out using integrated geological mapping and geochemical survey of soils, stream sediments and exposure of pegmatite/quartz veins. This was done in order to define the ore forming elements distribution and recognising type and area of possible mineralization in Kaiama and environ.. Eighteen samples were collected and analyzed for major and trace elements by x-ray fluorescence (XRF) and particle induced x-ray emission (PIXE) methods. Petrological description of thin sections of rocks was also carried out under the petrological microscope.The rocks underlying Kaiama consist of amphibolites, mica schists and granites along with fracture controlled mostly sheared mineralised pegmatite and quartz veins The fractured filled veins mainly trend NW-SE, NNE-SSW and E-W, N-S as to compare closely to the general trend of structures resulting from Pan-African orogeny. The mineralisation notably includes columbite-tantalite, rutile, cassiterites, ilmenites, wolframites, gold and gem stones. Geochemically, the trace elements concentrations shows significant anomalous concentrations of Sn, S, Ti, W, Au, Cu, Ti and Nb in the soil and stream sediments and Sn, W, and Nb in the veins. In addition, Zn, Cr, Co, Ni, Cd, Sb, Mo, V, As, Pb, Rb occurs in less significant anomalous concentrations in all the geologic media. The anomalous magnitude however decreases from soil to stream sediments and least in the veins. Further exploration work should be concentrated on soils and stream sediments towards delineating the possible ore deposit in the area of Kaiama and environs.
ORIGINAL RESEARCH ARTICLE | Nov. 28, 2019
Rhesus Negative Mother and Perinatal Outcome
Alakananda, Meghna Das, Manali Paul
Page no 284-387 |
10.36348/sijog.2019.v02i11.006
Background: Rhesus incompatibility is a preventable cause for severe neonatal hyperbilirubinemia, hydrops fetalis and still births. The prevalence of the Rh-negative blood group among Indian woman varies from 2%-5%. Despite declining the incidence of Rhesus incompatibility, due to availability of anti-D immunoglobulin, and improved antenatal care of the Rh-negative pregnant woman, it still accounts for a significant proportion of neonatal hyperbilirubinemia and morbidity. Objectives: To study the perinatal outcome in Rhesus negative Pregnancies. Methodology: This prospective observational study was conducted in a tertiary hospital. Women with Rh Negative Blood group admitted for delivery were enrolled. Baby’s Blood Group, Birth weight, TSB levels, duration of phototherapy or exchange transfusion, duration of NICU admission, and other investigations were recorded in a predesigned, pretested proforma. Conclusion: Over the 20th century, Rh isoimmunization was clinically recognized, its pathophysiology was understood, its treatment was established, and preventive measures were created to eliminate it. Awareness should be increased amongst health care providers regarding RAADP and prophylaxis after MTP, abortion, ectopic pregnancy in Rh negative blood group, and importance of Antenatal Care and importance of Rh typing in pregnancy.
ORIGINAL RESEARCH ARTICLE | Nov. 28, 2019
Food Effects Assessment on Oral Pharmacokinetics of Rosuvastatin in Wild Mice
Zoobia Irum, Abdul Aleem, Nasreen Ramzan, Inaam Ul Haq, Usman Abid, Shiza Murad
Page no 979-982 |
10.36348/sjmps.2019.v05i11.010
Rosuvastatin is regularly recommended for the treatment of hypercholesterolemia and applies its impact through focused collection in the liver. Current dosing rules show no inclination for sustained or fasted rosuvastatin organization. In this investigation, lower plasma level was noted in mice with nourishment 2 hours after an oral rosuvastatin portion, while liver fixation was unaffected. We presume that taking an oral portion with nourishment rather than on an unfilled stomach, don’t fundamentally influence the cholesterol-bringing down limit of rosuvastatin. Since a typical unfavorable occasion noted with statin treatment is muscle torment/harm related with high coursing statin levels, our discoveries can possibly fill in as a novel and basic system for relieving statin myopathy hazard.
ORIGINAL RESEARCH ARTICLE | Nov. 28, 2019
Analysis of Perceived Usefulness, Perceived Ease of Use and Service Quality on User Satisfaction in Using Snaapp Communication Application in Ignatius Slamet Riyadi Karawang Elementary School
Niko Faizal Akbar, Dan Adi Nurmahdi
Page no 849-855 |
10.36348/sjbms.2019.v04i11.005
This study aims to find out about: 1) the impact of perceived usefulness on user satisfaction, 2) the impact of perceived ease of use on user satisfaction, 3) the impact of service quality on user satisfaction, 4) the impact of perceived ease of use on perceived usefulness, 5) the impact of perceived usefulness and perceived ease of use on user satisfaction simultaneously. This is a quantitative research with parents from Ignatius Slamet Riyadi Karawang Elementary School as the population. The population of 300 people is narrowed down to 171 people as a sample using Quota Sampling and the Slovin formula. The data analysis with multiple linear regression shows that: 1) perceived usefulness has a positive and significant impact on user satisfaction, 2) perceived ease of use has a positive and significant impact on user satisfaction, 3) service quality has a positive and significant impact on user satisfaction, 4) perceive ease of use has a positive and significant impact on perceived usefulness, 5) perceived usefulness and perceived ease of use have a positive and significant impact on user satisfaction simultaneously.
ORIGINAL RESEARCH ARTICLE | Nov. 28, 2019
Simultaneous Estimation of Ibuprofen and Famotidine in Naturally Sweet Dispersible Pediatric Tablets by RP-HPLC
Vijay R Salunkhe
Page no 983-991 |
10.36348/sjmps.2019.v05i11.011
A new simple, accurate, precise and reproducible RP-HPLC method has been developed for the simultaneous estimation of ibuprofen and famotidine in naturally sweet dispersible pediatric tablets using C 18 column in isocratic mode. Methanol: buffer (90:10), pH 5, 25 mM; flow rate 0.9 ml/min; column length: 25cm is optimized. The flow rate was 1.0 ml/min and detection wavelength was carried out at 284 nm. The retention times of ibuprofen and famotidine were 5.293 min and 2.543 minutes respectively. The method was linear over the concentration range for ibuprofen 50-450µg/mL and 2-18µg/mL for ibuprofen and famotidine respectively. The recoveries of ibuprofen and famotidine were found to be in the range of 99.037-100.766% and 99.703-100.433% respectively. The validation of method was carried out utilizing ICH-guidelines. The described HPLC method was successfully employed for the analysis of pharmaceutical formulations containing combined dosage form.
ORIGINAL RESEARCH ARTICLE | Nov. 28, 2019
An Evaluation of the Relationships between Personality Traits, Job Satisfaction and Job Performance: An Empirical Study of Jordanian Hospitals
Nayel Mousa Rababah
Page no 839-848 |
10.36348/sjbms.2019.v04i11.004
The aim of this study is to examine the effects of personality traits (Big-Five personality) on both job satisfaction and job performance, and to evaluate how job satisfaction affects job performance in the case of the hospital sector. The collected data from 1200 employees in 52 hospitals in Jordan was analyzed, using structural equation modeling. The study finds out that the conscientiousness, extraversion, agreeableness, and openness traits exert positive effects, while neuroticism personality produces a negative effect on job satisfaction. Further, personality traits have a significant correlation with job performance. Job satisfaction has also significant effects on job performance. The empirical analyses yield results consistent with these arguments, personality traits assessed as predictors of job satisfaction and job performance. This study provides guidelines for the hospital sector to emphasize the attribute of employees that could affect and enhance their job satisfaction and performance. Implications for research and practice are correspondingly discussed.
ORIGINAL RESEARCH ARTICLE | Nov. 28, 2019
A Cross Sectional Study of Comparison between Individual Height and Median Nerve Conduction Velocity
Dipti V. Thakker, Viren B. Kariya
Page no 325-329 |
10.36348/sijap.2019.v02i11.004
Introduction: There is negative correlation between conduction velocities in both the Median sensory and Ulnar nerves and an individual's height, which likely accounts for the fact that, among most of the adult population, for each inch increase in height conduction velocities between the wrist and digits of an individual's hand decrease by 0.5 m/s. Consequence of it results in, impulse latencies within the Median, Ulnar, and Sural nerves increases with height. There is negative correlation between height and the amplitude of impulses in the sensory nerves. Functions of peripheral nerves and their parameters can be assessed by Nerve conduction studies (NCS). These parameters are known to vary with anthropometric measurements. Objective: To study the effect of height on the NCS variables in the median nerves of the limbs. Material and method: The study was conducted in 196 healthy individuals. The anthropometric parameters like height, weight and BMI were calculated. The compound muscle action potential (CMAP) and the sensory nerve action potential (SNAP) were recorded. Statistical analysis: The correlation of height with the median NCS variables were analysed by using Z test for two samples. Results: After the adjustment of other anthropometric factors, height (161.8673+8.140608) showed negative correlation with conduction velocities of median motor and sensory nerves of both the hands. Conclusion: Height showed a significant negative correlation with the median motor and sensory NCS parameters.
ORIGINAL RESEARCH ARTICLE | Nov. 28, 2019
Graphene Oxide: An Efficient and Recyclable Nano Catalyst for the Synthesis of 2-Substituted Benzimidazoles from Aldehydes and Diamines at Ambient Temperature
Zahra Moniri, Farahnaz K. Behbahani
Page no 115-126 |
10.36348/sijcms.2019.v02i07.002
The benzimidazoles skeleton, a category of heterocyclic compounds have important biological and pharmaceutical properties such as antihelminthic, antiulcer, diuretic, anticonvulsant, analgesic, antiulcer, antihypertensive, anticoagulant, anticancer, anti-inflammatory, antimicrobial, antiviral, antiparasitic and antioxidant. On the other hand, graphene oxide due to their operational simplicity, easy work up and inherent non-toxic, and possessing a wide variety of functional groups, such as epoxy, hydroxyl, and carboxyl, pays an important role in organic synthesis. Therefore, in this chapter graphene oxide was investigated as an efficient catalytic system for the preparation of benzimidazole compounds via the condensation reaction of o-phenylenediamines with aromatic aldehydes in very good yields at ambient temperature. The results in this method were compared with previously reported in literature respectively. Also graphene oxide was recovered and reused without decreasing in its efficacy for 3th runs.
ORIGINAL RESEARCH ARTICLE | Nov. 28, 2019
Perception of First Year Medical Students towards Newer Methods of Teaching in Anatomy
Asharani SK, Ajay Ningaiah
Page no 338-340 |
10.36348/sijap.2019.v02i11.007
Background: Teaching is a process of imparting a corpus of knowledge to a group of individuals. Teaching methods in Anatomy include dissection by students, demonstration of prosected specimens, the use of models and computer animations, instructional teaching, study of living anatomy by clinical examination and radiological techniques. The appropriateness of a teaching method to arrive at the desired specific learning outcomes is governed by the concept known as “fitness for purpose”. Aim: To gauge the perception of first year medical students regarding the newer teaching methods. Materials and Methods: The Questionnaire based study was conducted on 150 first year medical students of Adichunchanagiri Institute of medical sciences, B G Nagara. The data obtained was statistically analyzed. Results: 26.7% of the participants were of the opinion that newer methods of teaching will help in learning anatomy, whereas 67.3% felt that older methods are effective in teaching. Conclusion: Effective methods of teaching and learning will improve knowledge retention of basic science subjects like anatomy. A sound knowledge in the basic sciences is very valuable in clinical settings; it allows the students to understand the association between presenting clinical features and diagnoses.
ORIGINAL RESEARCH ARTICLE | Nov. 28, 2019
A Report on Multiple Births in Hanuman Langur (Semnopithecus Entellus) in and Around Jodhpur, Rajasthan
Goutam Sharma
Page no 355-359 |
10.36348/sjls.2019.v04i10.004
The present study covers multiple on Hanuman langurs, Semnopithecus entellus, and species living around Jodhpur, India. The current statement delivers report multiple births during 2018-2019. Four cases of multiple births (three twins and one triplet birth) were observed during study in species at Jodhpur. The adult female with twins/triplet birth expended more time in foraging and resting. The research suggested that adult females with multiple deliveries can successfully survive in a study environment.
ORIGINAL RESEARCH ARTICLE | Nov. 28, 2019
Breast Cancer in Association with Thyroid Disorders
Anil Batta
Page no 262-267 |
10.36348/sijb.2019.v02i11.001
The relationship between breast cancer and thyroid diseases is controversial. Discrepant results have been reported in the literature. The incidences of autoimmune and nonautoimmune thyroid diseases were investigated in patients with breast cancer and age-matched control individuals without breast or thyroid disease. Methods: Clinical and ultrasound evaluation of thyroid gland, determination of serum thyroid hormone and antibody levels, and fine-needle aspiration of thyroid gland were performed in 150 breast cancer patients and 100 control individuals. Results: The mean values for anti-thyroid peroxidase antibodies were significantly higher in breast cancer patients than in control individuals (P = 0.030). The incidences of autoimmune and nonautoimmune thyroid diseases were higher in breast cancer patients than in control individuals (38% versus 17%, P = 0.001; 26% versus 9%, P = 0.001, respectively). Conclusion: Our results indicate an increased prevalence of autoimmune and nonautoimmune thyroid diseases in breast cancer patients. There is always a controversy on the relationship between breast cancer and thyroid disorders. As these tissues, i.e., breast and thyroid, originate embryologically from the same type of cells, hypothyroid/hyperthyroid females are more prone to develop benign or malignant breast tumors. The studies on breast cancer patients indicate increased thyroid disorders in breast cancer patients, most commonly Hashimoto's thyroiditis accounts to increased thyroid disorders in these patients. This is independent of hormonal receptor status of the patient. These findings suggest the usefulness of screening for thyroid disease in any patient with breast cancer.
CASE REPORT | Nov. 28, 2019
A Rare Case Report of Granulomatous Inflammation of Gall Bladder with Review of Literature
Bhavna Valecha
Page no 846-848 |
10.36348/sjpm.2019.v04i11.013
Introduction: Gallbladder tuberculosis (GBTB) is an exceedingly rare finding presenting as calculous or acalculous cholecystitis. A correct, preoperative diagnosis of GBTB is difficult, and the literature review highlights the fact that most cases are diagnosed postcholecystectomy or at postmortem. Discussion: Mycobacterium tuberculosis can affect any part of the gastrointestinal tract from the mouth to the anal canal along with the other organs of the peritoneal cavity, but the gall bladder is unlikely to be primarily involved. The incidence of localization of the tubercular bacilli in the gall bladder is uncommon as the intact gall bladder mucosa is resistant to the bacterium because of the concentrated bile acids present in the organ. The first case of gallbladder tuberculosis (GBTB) was reported in 1870 by Gaucher, and till now, less than 120 cases have been reported in the English medical literature [4, 5].
ORIGINAL RESEARCH ARTICLE | Nov. 28, 2019
Brain pathology in Adult Rats Treated with Tetrodotoxin
Thilagar Gobinath, Samuthirapandian Ravichandran
Page no 849-857 |
10.36348/sjpm.2019.v04i11.014
Puffer fish poisoning remains a severe seafood poisoning condition blamable for numerous human intoxications. Research on puffer fish poisoning enables studying the involvement of puffer fish poisoning in human security. The current study thus intention of investigating whether Arothron hispidus from the south-east coast of India (Palazhyar) cause for the neurodegeneration. Cresyl violet stained sections of the rat brain regions examined for pathological changes in rats treated with A.hispidus toxic extract. We noticed disarrangement and neuron loss in the primary motor area, hippocampus, amygdala, thalamus, temporal lobe, parietal lobe, and cerebellum regions of rats treated with A.hispidus skin extract. Damaged regions directly or secondarily associated with sensory and motor functions, this may cause loss of sensory and motor function. From our observation, we conclude that neuronal loss of a rat's brain treated with skin extract as clear through histopathological analysis, due to the neurotoxic effect of Arothron hispidus.
CASE REPORT | Nov. 28, 2019
A Case Report of Follicular Cholecystitis with Review of Literature
Bhavna Valecha, Hemlata Kamra
Page no 829-831 |
10.36348/sjpm.2019.v04i11.009
Introduction: Follicular hyperplasia of the gall bladder is an extremely rare and benign entity characterized by hyperplastic lymphoid follicle with germinal center consisting of the lymphoid population. The lymphoid hyperplasia of the gallbladder is a rare condition, which can be diagnosed only by performing a histological examination. Here, we present the case of a 36-year-old woman with complaints of repeatable pain in the area of the right hypochondrium for a few months. Ultrasonography revealed chronic cholecystitis with a concrement in the lumen. Methods and Materials: We were reported a rare case of follicular hyperplasia of gall bladder in a 36 yrs old female presented into the department of surgery with a right side upper abdomen pain then she was diagnosed as cholecystitis and managed by cholecystectomy and specimen was received and processed for histopathological examination. Results: Due to chronic cholecystitis patient present with right upper abdominal pain and upon histopathological examination diagnosed incidently as follicular cholecystitis. Conclusion: Histopathological examination reveals a rare case of follicular cholecystitis A cholecystectomy was then performed. Histology shows nests of cells with lymphoid origin in the lamina propria, a multitude of lymphoid follicles and areas with pyloric metaplasia in the gallbladder wall. The case presented herein is of reactive lymphoid hyperplasia resembling a lymphoma combined with chronic cholecystitis, pyloric metaplasia, and cholelithiasis.
ORIGINAL RESEARCH ARTICLE | Nov. 28, 2019
Molecular Characterisation of Isolates Belonging to Candida Parapsilosis Species Complex and Determination of Their Antifungal Resistance Profiles
Caner Yuruyen, Ahmet Mert Kuskucu, Kenan Midilli, Zayre Erturan, Gulden Celik
Page no 837-841 |
10.36348/sjpm.2019.v04i11.011
Introduction: This study aimed to differentiate among the species belonging to the Candida parapsilosis complex, which is one of the leading causes of systemic mycoses through molecular characterisation and to determine their antifungal resistance pattern. Material and Methods: Ninety-five C. parapsilosis complex isolates identified using two yeast identification systems, BioMérieux ID 32C and Vitek 2™ with YST card, were included in this study. Molecular characterisation was achieved by polymerase chain reaction–restriction fragment length polymorphism analysis of the secondary alcohol dehydrogenase gene. Isolates that could not be identified using this technique were identified by internal transcribed spacer (ITS) sequencing. Antifungal susceptibility was evaluated using the Vitek 2™ AST-YS06 card. Results: Out of the 95 isolates, 94 were identified as C. parapsilosis sensu stricto, and only one isolate was identified as C. orthopsilosis; the latter result was achieved using ITS sequencing. C. orthopsilosis was susceptible against all tested antifungal agents. Among the C. parapsilosis sensu stricto isolates, three were found to be resistant: one to amphotericin B, two to fluconazole of which one showed intermediate resistance to voriconazole. Discussion: Isolation rates of C. orthopsilosis and C. metapsilosis in this study show that they are rare species. It was not possible to compare resistance among these three species due to very low isolation rates of C. orthopsilosis and C. metapsilosis. The use of molecular identification tests for these species in routine laboratory settings remains controversial. Nevertheless, their isolation rates and antifungal resistance patterns are important from the epidemiological viewpoint.