Background: Human body is still in the process of evolution. Incorrect ergonomics at workplace including working from home is not free from serious long-term health effects. Lockdown during COVID-19 pandemic, people stayed indoors. This has led children to depend on online classes, training and meetings. In view of this, study was undertaken to assess the effects of ergonomic settings on children spending more time on devices. Methods: About 186 children (aged between 10-18 years of both sexes) and their parents volunteered to respond to online survey with a questionnaire covering awareness of parents on ergonomics, problems encountered by children on ‘make-shift’ workplace adjustments, hours of sitting, screen time, eye-monitor ergonomics, backrest, footrest, keyboard & mouse ergonomics, breaks during work and gadgets they used. Problems encountered by the children were analysed. This was conducted 60 days after the first day of lockdown in Hyderabad (23 March 2020). Results & Discussion: Children spent longer hours on gadgets, on laptops (58%), android / apple phones (20%), desktops (12%) and tablets (10%). Their content on gadgets was 45% curriculum, 35% games and 20% others. Study revealed that parents were unaware of ergonomics and effects on their children. Very few parents understood the correct sitting posture (6%), eye-monitor ergonomics (1%), laptop ergonomics (3%) and (38%) importance of breaks. About 21% of subjects suffered upper back pain, 18% lower back pain, 13% eye strain, 11% headache, 6% had irregular sleep and 6% behavioural changes. Effects of wrong posture during work, repetition, loading and probable cause for pain were discussed in the paper. Conclusion: This pilot exploratory study revealed that parents and students were not aware of ergonomics. In a short duration of two months, lot of them have developed significant problems and this may increase the risk of many painful syndromes in future. These incorrect student-occupation practices may develop into permanent habits. There is a need of inclusion of ergonomics and workplace management in school curriculum, parents and teachers need training in the subject. More controlled studies are required to develop lifestyle strategies to combat these inevitable problems.

Chinese films and TV attract global audience in recent years, as is the case of Empresses in the Palace, the subtitle translation of which plays an important role. This paper attempts to make a case study of the TV drama Empresses in the Palace from the perspective of Eco-translatology. By exploring how the three-dimensional transformations are applied in its subtitle translation based on the statistical results, the paper aims to bring more enlightenment to China's film industry by discussing the practical translation methods and techniques. It can be concluded that translators need adapt to the translational environment and make adaptive selections for different dimensions of the subtitle translation.

Physical activities in young people. The concept of the game as a cultural phenomenon was partly influenced by the ideas of different studios. The aim of this study was to examine the nature of the physical activities practiced by young people in their leisure time through questionnaires. Study sample. This study involved 126 young people: 66 girls and 60 boys, aged between 15 and 18 years old. They study in three different schools of Tirana. In both studies there are three main reasons for practicing informal physical activities: "because they like it“, "for fun and enjoyment" and "for exercising". Since the type of activities carried out during leisure time will affect many aspects of life persons, it is important to prevent these young people from becoming adults and spending most of their leisure time in sedentary activities.

Building strong resistance against the Covid-19 is now the major challenge around the world. Since there is no reliable remedy, many strategies have been adopted so far to get rid of it. It is already prevalent in a number of countries, but in most cases it has been made possible by lockdowns and adherence to unlimited hygiene as relaxation of these intitiatives causes re-infection. While the whole world is worried about Covid-19, Bangladesh, a South Asian country, is plagued by various dangers, which is causing a lot of frustration among the people of this country. Dengue, floods and waterlogging, indifference to human health and shaky government management are rampant in this country. However, it is only a matter of time before a strong fight is waged against Covid-19, as the country looks to the world for a vaccine, which is deteriorating overall situation. In this article, some of the things to do in the world like Bangladesh and this country have been highlighted.

Background: The researcher motivated a group of Govt. servant to start morning walk for the benefit of their health & fitness. At the very outset researcher discuss and assured them to monitor the training program targeted for the improvement of their health & fitness status and at the same time he thought to conduct a research work on them. Objective: The objective of this research work was to find out the effectiveness of morning walk on WHR, BMI, BP and RHR in Bengali men under the age of 40 years. Methods: Total thirty (N = 30) male Govt. servant, few office workers & few school teachers, were considered as subject for the present study. They were purposefully divided into two equal groups – One group was treated as experimental group (n=15) another group was treated as control group (n=15). The age of the subjects were ranged from 35 to 40 years. The subjects of experimental group were motivated and all the subjects were participated spontaneously in the morning work program followed by some free-hand and starching exercises for a period of 32 weeks. On the other hand the subjects of the control group were chosen from the same pair population of the age group who were not any history of participation in regular physical activity. Therefore, the control group was free from the morning walk program. In the present study WHR, BMI, BP and RHR were considered as variables. Data were collected in Pre intervention and Post intervention of the morning walk program both for the experimental as well as control group by using standard tools & techniques. To draw the inferences the data were analyzed by using analysis of covariance (ANCOVA). It was tested at p < 0.05 level of significance. Results: A significant improvement was observed in BMI, WHR, BP (systolic blood pressure & diastolic blood pressure) and resting heart rate of less than forty year men. Conclusion: Regular morning workings have significant impact on WHR, BMI, BP and RHR.

Functional training is a classification of exercise which involves training the body for the activities performed in daily life. Yoga is an ancient Indian way of life, which includes changes in mental attitude, diet, and the practice of specific techniques such as yoga asanas (postures), breathing practices (pranayamas), and meditation to attain the highest level of consciousness. This study was conducted with the purpose to find out the combined effect of functional fitness training with yogic practices on selected physical and physiological variables of homemakers. Parallel group experimental design was formulated for this study. The selected 40 homemakers were randomly divided into two equal groups 20 on each group. (Experimental & Control group). The package of combined functional fitness training with yogic practices was incorporated to the experimental group, for 12 weeks, weekly three days, one hour in the evening session. The pre and post tests were conducted on the selected physical (flexibility, CVE) and Physiological variables (Pulse rate, BP & lung capacity) on the subjects of both the groups administering standardized tests of sit and reach, 9 minutes run and walk test, manual, monitary and wet spirometry. The collected data was analyzed by using the following statistical tests. The pre-test and post test scores were subjected to statistical analysis using paired ‘t’ test and in all cases 0.05 level of significance was fixed to test hypothesis. Functional fitness training associated with yogic practices showed a significant contribution to improve the Flexibility, Cardio Vascular Endurance, lung capacity and maintain Blood pressure and Pulse rate.

The presence of the sports can historically contribute international understanding and cooperation. Olympic and Paralympic Games in Tokyo will be scheduled, and “Exercise is Medicine” has been known widely by American College of Sports Medicine (ACSM). Authors et al. have continued clinical practice and research on pole exercise for years. The methods include various movements in frontal, horizontal and sagittal planes. The pole consists of aluminum with 60-160 cm in length. Moriyasu pole training would be clinically effective, which can simultaneously increase the flexibility of thorax, vertebrae and pelvis, and the functioning ability of joint movement and posture control.

This research aims to analyse the influence of return on equity, debt to asset ratio, working capital turnover and dividend payout ratio to stock return and to know the factors of return on stock. The data source used is the secondary data obtained from the annual report of the food and beverage sub-sector manufacturing company listed on the Indonesia Stock Exchange (BEI) in 2014-2018. This research uses causal research design, the method used in this research is the purposive sampling method. The data analysis methods in this study used multiple linear regression analyses and their data processing using version 21 programs. Based on purposive sampling method, there are 65 final samples this research. The method of analysis used is statistical analysis in multiple linear regression test forms. Overall, the results of the study revealed that Return on Equity (X1) has no significant effect on the stock return, Debt to Asset Ratio (X2) has no significant effect on the stock return, Working Capital Turnover (X3) has a significant influence on the stock return, Devidend Payout Ratio (X4) has no significant effect on the stock return.

Introduction: Laboratory tests are important for the confirmation of the diagnosis of the disorders and also they are required to see the prognosis or to monitor the effects of the treatment of diseases. Many laboratory tests are ordered inappropriately, some of the ordered tests reports have not been utilized neither for the diagnosis nor for the assessing the prognosis of the disorders. Methodology: Source of data was obtained by documentation maintained in the inpatient registers for routine and emergency tests. Study type and design is Descriptive Cross Sectional study. Results: The percentage of total number of investigations increased was calculated from the year 2007 to till 2016. In our study we found that there was more than 1000% increase in the laboratory workload over a period of 10years both for elective and emergency (around 742%) sample analysis. Discussion: There is an increase in the workload of both routine and emergency tests which were done in Central Biochemistry laboratory and found out the normal value reports in some samples, which were required neither for the diagnosis nor for the prognostic purpose of the disorders. Conclusion: The study revealed gross overuse of laboratory; the ordered tests were required neither for the diagnosis nor to see the prognosis or to monitor the treatment of the disorders. This inturn affect the patients and organization in terms of direct cost & indirect cost. Inappropriate tests may increase the laboratory overload which affects laboratory results adversely in terms of the quality and availability of the laboratory resources.

Breast cancer is the most common occurring cancer among women worldwide. Risk factors included drinking lot of alcohol, lack of physical exercise, family history, ionizing radiations and hormones replacement therapy during menupuase. BRAC1 gene play important role in biochemical processes occurring in cells of the breast cancer. It is highly abundant in tumor cells as compared to the normal cells of human body. It makes it strong and ideal candidate for biochemical and functional characterization at molecular level. The molecular pathways associated with tumor formation and progression of breast cancer not completely discovered yet. There is need to design such potential target or drugs that can target the cells of breast cancer and regulate the epithelial mesenchymal transition as well as reduces the number of cases due to breast cancer. Information regarding genes involved molecular pathways remains unclear. There is need to identify genes involved inthe development of breast cancer as well as prognosis. GEO database of NCBI especially used for breast cancer datasets searching.Cytohubba is used to identify the DEGs. Functional enrichment software that is used for classification and characterization of genes at functional level. Biological database such as STRING that designed for to construct PPI networks of DEGs. MCODE in Cytoscape-Intergerated plug in experimentally applied to check the interactions in PPI network. Cytohubba also used to check out the either hub genes functional or target newly drug for the breast cancer treatment. Kaplan–Meier is biological software that is used to check out the survival of individual hub genes subjected to breast cancer. X2K (Expression2Kinases) used to check out the expression of hub genes. The between hub gene and drug especially be designed in database of drug bank.

The cytogenic study included 20 mentally retarded children within the age group of 1 to 16 years, were evaluated for numerical chromosomal abnormalities. Out of 20 subjects, the first 11 samples were taken from the children of the school of the Mentally Retarded People, university road, Rajkot and the rest 09 samples were collected from the patients visited to Psychiatric OPD at the Government Civil Hospital, Rajkot. 15% female subject while 85% male subjects were evaluated for the present study. The selection criteria were children of the age between 1 and 16 years and the confirmation of mental retardation. The severity of category of mental retardation has not been focused. Chromosome preparation from peripheral blood cultures was done using standard techniques and cytogenic analysis was performed using GTG-Banding technique. 10% Karyotype were observed with numerical chromosomal abnormalities and that is Trisomy of 21st pair of chromosome. The study concluded that chromosomal abnormalities are thought to be the most common cause of mental retardation. However, apart from a few selected types with typical aneuploidy, like Down’s syndrome, the frequency of detectable chromosomal abnormalities in association with idiopathic mental retardation is very low.

In Ayurveda, ahara (food), swapna (sleep) and brahmacharya (celibacy) are considered as tryo-upasthambhas or sub-supporting pillars of life. Food is critical for the sustenance of life; it is the first of the three, followed by sleep and brahmacharya. Foods are any substances containing nutrients, such as carbohydrate, proteins and fats that can be ingested by a living organism and metabolized into energy and bodily tissues. Digestion is the process of breakdown of complex form of food into simplest monomers through enzymatic process in gastrointestinal tract. In Ayurveda, conversion of hetrogenous panchbhautic ahara (complex food) into its basic homogenous panchmahabhuta (simplest monomers) is directed by the synchronization of three sets of agni; jathragni, dhatwagni and bhutagni. The process of digestion, metabolism and assimilation is mainly accomplished by agni. The site of jathragni is grahani or pakvamashaya better known as pittadhara kala. Samana vayu, Pachaka pitta and kledaka kapha helps in digestion. Samana vayu which is present near the vicinity of agni stimulate the pachakagni for the digestion and separation of food. Kledaka kapha is present in the stomach which softens the food materials. Ayurvedic classics explains the whole process of digestion that starts with the intake of food, takes place in three stages called as Avastha paka, these are Madhur avastha paka, Amla avastha paka and katu avastha paka. Few works have been mentioned on conceptual features of avastha paka in relation to modern physiology. In this article correlation of the physiological concept of avastha paka with modern medical science has been stated. For this study, the basic materials have been collected from the Ayurvedic classics with the available commentaries, as well as Text books of modern medical science better understanding of the concept and its comparison with contemporary science.

Throughout a long time, green chemistry (GC) reviled how a basic scientific methodology and advanced practice can enhance the safe output to human life and the environment without compromising the desired outcomes. For this, advancements in scientific processes have been made in the field of designing safer reagents and solvents, advancement in catalysis and possible development of the renewable feedstock. From the chapters of the past, future chemists are being taught and trained to a wider concept of green chemistry to practice and increase awareness towards human as well as environmental impact. Green Chemistry practice is in high demand and the adherence to the 12 principles of the Green Chemistry concept is growing rapidly. A need for great change in policy, rules and regulations that will force industries, research institutes, academics, and others are still needed more than ever. Moreover, better encouragement, awareness and making an individual person responsible to adapting to a Green Chemistry concept in a real practical way, are needed. Green actions are always louder than green words.

Background: The present study is undertaken with limited available facilities to find out the efficacy of two oral antihypertensive drugs namely labetalol and methyldopa in management of pregnancy induced hypertension. Methods: The study consisted of 150 patients with pregnancy induced hypertension attending outpatient department and admitted in ANW, or who directly came to labour room. These patients were randomly selected on lottery basis after they fulfilled the inclusion criteria. Total 150 patients were taken for the study and divided into 2 groups of 75 patients in each group. Results: The mean SBP before treatment in methyldopa group was161.33 ± 8.97 mmHg and 160.03 ± 8.23 mmHg in labetalol group which showed a fall to 138.61 ± 6.67 mmHg (methyldopa group) and 138.08 ± 5.37 mmHg (labetalol groups) after treatment. Fall of SBP was significant in both the groups. But inter group difference was not significant (p > 0.05). The mean DBP before treatment was 106.85 ± 4.33 mmHg in methyldopa group and 105.63 ± 5.23 mmHg in labetalol group which decreased to 89.31 ± 6.51 mmHg and 89.68 ± 5.26 mmHg respectively after treatment. Fall of DBP was significant in both the groups. But inter group difference was not significant (p > 0.05). Fall of MAP was significant in Group A and Group B. But inter group difference was not significant (p > 0.05). Conclusion: Labetalol and methyldopa are equally efficacious in controlling blood pressure in new onset hypertension in pregnancy.

The purpose of this study is to analyze the effects of Profitability, Leverage, and Liquidity on Financial Distress which is proxied using Z-scores. The object of research is the sub-sector of property and real estate companies listed on the Indonesia Stock Exchange in 2016-2018. This research was conducted using a sample of 47 companies listed on the Indonesia Stock Exchange. Determination of the sample using a purposive sampling method with criteria by researchers using a causal relationship design. The analysis of data use statistical analysis in the form of multiple linear regression tests. The result of this study is that profitability, and liquidity variables have significant effects and positive on financial distress. The Leverage variable has a significant effect and negative on financial distress. While The Audit Committee has no effect on financial distress.