Capital Punishment for illegal narcotics traffickers is indeed needed to reduce the crime in the community, even though the polemic in the enforcement of this punishment still arises because it is closely related to human rights enforcement. This research intends to examine weaknesses in the imposition of Capital Punishment based the view of Pancasila philosophy as well as the ideal construction of the Capital Punishment regulation in narcotics and psychotropic offenses based on Pancasila values. The type of writing used in this research is normative legal research method. The method of normative legal research is legal research that places law as a norm system building. The results show that capital punishment can be accounted for in the Pancasila state which is manifested as individual protection as well as protecting society for the creation of justice and legal truth based on the almighty God. The Capital Punishment, from the perspective of Pancasila, is seen as one unity. Pancasila must be the basis for seeing the Capital Punishment as In its implementation, the Capital Punishment for narcotics and psychotropic offenses still has weaknesses therefore it need an ideal construction of the regulation of the Capital Punishment in narcotics and psychotropic offenses based on the values of Pancasila is carried out with due regard to the main crime. With this reconstruction, The Capital Punishment will be a special punishment that can be applied carefully, selectively and specifically in dangerous cases as it must be determined unanimously by the panel of judges first.

The paper represents the challenges of Georgia’s capital market, its importance for economic development and diversification of the financial sector. Capital markets have an increasing role and weight in Georgia’s economy. The formation of the capital market is a long process as it requires the formation of the financial instruments, market infrastructure and institutions. Considering the capacity of economy and its potential benefits, Georgia has less developed economy and therefore, the capital market is underdeveloped. The paper analyzes the prerequisites for forming and developing the capital market in Georgia, as well as its characteristics. In this paper we investigate the several sources for financing gross financial needs and for making optimal decision, which type of instrument should the government of Georgia use before raising funds, we compare the financial conditions of the existing sources with each other.

A company increases profits every year in order to keep reaching a larger target. It can be reached if each employee is having an Organizational Citizenship Behavior (OCB). The aims of this study are to measure and analyze the influence of job satisfaction, Perceived Organizational Support (POS), and organizational climate through OCB of the employee on employees in an outsourcing company Jakarta. The population of this study was all employees in the outsourcing company, which were 72 respondents. The sampling technique used in this study was saturated sampling with all employees for the object. This study used a linear regression method to analyze data. The finding of this study was job satisfaction, POS, and organizational climate variables have significant correlations to OCB. This study also showed the most variable that influencing OCB was job satisfaction.

Currently, maintaining good hygiene and sanitization as a precautionary measure is of importance to avoid the spread of the novel Coronavirus. As a part of prophylaxis during the COVID pandemic, hand sanitizing gel was formulated in Riyadh Municipality Central Area Laboratories based on WHO guidelines. The gel was evaluated by physical, chemical and microbiological testing and compared with five commercially available hand sanitizers in Riyadh City. The results revealed that the laboratory formulated gel has a pH of 6.0 and 80% ethanol vlv, with very strong antibacterial activity recorded in the range of 20.1 to 21.2 mm against five selected bacterial strains with highest activity against E.coli ATCC 25922. The minimum inhibitory and minimum bactericidal concentration was observed to be 12.5% and the gel was able to kill the bacterial flora on volunteers hand by a Mean cfu reduction of 99.24% in 30 seconds. The results obtained in this study demonstrate that laboratory formulated gel is highly effective than 5 commercial brands against all the bacterial strains tested.

Nutrient canals are radiolucencies seen in the alveolar bone which are considered to be the channels that contain blood vessels and nerves supplying the teeth and the supporting structures. They are also called as circulating canals, interdental channels and vascular canals. They are predominantly seen on the intraoral periapical radiographs in the mandibular anterior region. Though they are considered to be normal, according to literature, some investigators have correlated the radiographic appearance of nutrient canals with certain pathologic conditions. Hence this study was undertaken to rule out the association as well as prevalence of nutrient canals in patients with systemic conditions like hypertension and diabetes.

The Constitution of India is established upon the fundamental guideline of Rule of Law which in itself incorporates quality of Law. What's more, the Preamble to the Constitution depicts the thought where Justice, Freedom and Equality is to be made sure about to all the residents and Fraternity must be advanced among all the residents. However, it has been a long time since the Constitution was ordered and we have neglected to guarantee that they are being followed. The term 'We' incorporates the Legislature, Executive and Judiciary yet additionally the nation all in all. Crowd Violence is one of such territories where standards cherished in the Constitution are disregarded. In this article, the writers give a short review about the reasons related with crowd brutality, the current law in this regard and the location a significant issue of whether an explicit law is required. In this examination paper, I would concentrate on the current legitimate arrangements concerning savagery, the issues with these arrangements and requirement for extraordinary laws managing such viciousness with the assistance of doctrinal examination. I would likewise study the circumstance on different nations where such viciousness is pervasive and look at the techniques received by them to check such viciousness. I would likewise bring up the proposals made by the Supreme Court just as the bills presented by the Members of Parliament to check such viciousness.

Nowadays, although the technology keeps developing, the quantity of human resources who have competence and expertise in sharia economic continues to be minimum. It gives several direct impacts on sharia banking. One of the direct impacts is high turnover intention. The purpose of this study was to look at the Transformational Leadership effect, Perceived Organizational Support, and Workload on Turnover Intention in one of sharia banking in Jakarta. Samples of the study were employees who worked at one of sharia banking in Jakarta. Sampling was conducted using nonprobability techniques, which is purposive sampling with the Slovin formula of 101 people. This study was conducted quantitatively, and the analysis method used in this study was multiple linear regression analysis. The results of the study showed that transformational leadership, perceived organizational support and workload variables have a significant effect on turnover intention. The result of the study also showed that what affects turnover intention the most is workload. It was proven by the results of the simultaneous test (F test) and partial test (t-test) which showed the numerous value of three independent variables that supported the hypothesis.

Steven-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are potentially life-threatening mucocutaneous diseases characterized by hypersensitivity to medication and infections. Inspite of complete recovery from skin problems without sequelae, survivors can land with serious ocular complications culminating in blindness irrespective of intensive local and systemic therapy. We are describing the clinical course and treatment of a patient with TEN who developed bilateral ankyloblepharon after recovery from the acute attack. Amniotic membrane was applied to the ocular surface of the patient after correcting the ankyloblepharon. Amniotic membrane transplantation (AMT) has been proven to be an effective mode of treatment for severe ocular surface and eyelid inflammation as it decreases the risk of ocular and visual sequelae. Early detection of complications and aggressive treatment of the same are essential for preservation of vision.

Malaria is a life-threatening disease with high mortality and prevalence especially in children under the age of 5. Herbal remedies like Nauclea latifolia have been used and found to be effective in the treatment of malaria. However, presentations like decoctions, liquid extracts are not suitable particularly for children. Therefore, in this study, syrup formulations of the dried aqueous root extract of Nauclea latifolia (AREL) were developed using honey, simple syrup BP and water as vehicle in the presence and absence of a sweetener, thickener and preservatives. Organoleptic and physicochemical properties such as odor, color, taste, homogeneity, pH and density were evaluated. Stability of the syrups at room temperature, in the refrigerator and at accelerated temperature was also evaluated. In vivo anti-plasmodial activity of optimized syrup formulation was investigated according to standardized methods. Results show the syrups were brown to amber in color, homogenous and had sweet to bitter taste. The pH of the syrups were between 4.45 and 5.78, flow rate was between 0.00 and 2.17 g/sec. Density was between 1.24 and 1.41 g/mL; syrups containing honey were non-flowing while those formulated with simple syrup were more free-flowing. In vivo studies show that the optimized syrup formulation possess ability to inhibit parasitemia. No observable changes were noticed after the period of storage. This study shows that the development of the dried aqueous root extract of Nauclea latifolia into syrups as a standardized dosage form capable of inhibiting parasitemia could be explored.

Medicinal plants are source of a great economic value. Plants herbs are naturally gifted at the synthesis of medicinal compounds. The extraction and characterization of bioactive compounds from medicinal plants have resulted in the discovery of new drugs with high therapeutic value. Baobab Adansonia digitata L., (Malvaceae) seeds were collected from El-Obeid, North Kordofan state Sudan, and were extracted with hexane as solvent the extracted oil was analyzed by GC-MS. Twenty four constituents were detected the major constituents are: 9-octadecanoic acid methyl ester (25.08), 9,12-Octadecadienoic acid (Z,Z)-, methyl ester (23.08), Hexadecanoic acid, methyl ester (22.78), Methyl stearate (6.86) and Methyl 2-octylcyclopropene-1-heptanoate (6.08). In the well diffusion bioassay the oil showed significant activity against Bacillus subtilis, Pseudomonas aeroginosa, Staphylococcus aureus, and the yeast Candida albicans but it was partially active against Escherichia coli. The antioxidant activity of the extracted oil was evaluated using the standard 2, 2diphenyl-1-picrylhydrazyl (DPPH) 0.5 ml. The antioxidant activity of the extracted oil was 19.00 ± 0.08

We discovered during a dissection of the callot triangle during a cholecystectomy a doubling of the cystic artery, discribed being a rare variation of cystic artery.

The human pathogen, Entamoeba histolytica contains four Sir2 homologs in its genome. We have designed the 3D tertiary structure of EhSir2a and its interacting partners by comparative homology modeling and studied their interaction by molecular docking. Sir2 proteins are known to interact with their substrates through the deacetylase domain present in its C-terminus. Interestingly, EhSir2a contains a unique Zn finger domain at its N terminus and this is not present in any known Sir2 protein. This study shows that EhSir2a may interact with this N-terminal residue also. It interacts with its substrate, elongation factor EhEF2 through this zinc-finger domain. The interaction sites are different for alpha-tubulin homologs, the other substrates of EhSir2a identified by yeast two-hybrid library screening. The coordinate files of the best-modeled structure for EhSir2a and its interacting proteins were processed for protein-protein docking using ClusPro v2.0 and HawkDock server. Tyr432, Asn422, Arg408 residues of α-tubulin are essential for interaction with EhSir2a. Here we report that molecular interactions of EhSir2a with its interacting partners are not restricted to the conserved NAD+ dependent deacetylase domain; it may also involve the N-terminal residue.

Background: Physical inactivity has been listed as one of the global health problem by WHO and is one of the important risk factor for development of non-communicable diseases like diabetes, cardiovascular illness and some malignancies. Regular physical activity plays a significant role in preventing the development of non-communicable diseases. Students of medicine in spite of having considerable knowledge about the benefits of physical activity the occurrence of physical inactivity is also common because of lack of time and busy academic schedule. Hence the present study was taken up to assess the background knowledge, barriers and motivational factors for the practice of physical activity and to study the pattern and duration of physical activity among first year medical students. Methods: A cross sectional study was conducted among 130 medical students. A pre-tested, semi-structured questionnaire was used to collect the data. Descriptional statistical analysis was done and results were expressed as percentages. Results: in our study majority of the students said they would like to practice some form of physical activities because of the health related benefits of the same. The pattern of physical activity practiced is mainly sports related which can be attributed to the younger age of the study population. Conclusion: we conclude that there is a greater need to encourage students to practice physical activities in some feasible form during their medical training so as to inculcate good practice of regular physical activities into their own lifestyle and advice their future patients regarding the health benefits of regular practice of physical activity.

Background: Diclofenac (DCF) is a drug widely consumed in developing countries like Nigeria, because of its fast and immediate effect on pains. Objectives: The high number of adult males falling victims to BPH made DCF a suspect in the predisposition to BPH. Methods: Thirsty Six (36) Male Wistar albino rats were divided into five groups of six animals each. Group 1; the Normal control (NC) was injected subcutaneously with olive oil only, Group 2; standard group treated with testosterone Propionate in olive oil (3 mg / kg b.wt.). Groups 3, 4, and 5 were treated with Diclofenac, potassium in solution as low (2 mg / kg b.wt.), mid (4 mg / kg b.wt.), and high (6 mg / kg b.wt.) doses respectively. All animals were fed same diets throughout the twelve (12) weeks. After this period, the rats were allowed to fast overnight then Blood samples were collected and analyzed for liver function, kidney function, lipid profile, prostate specific antigen (PSA), and haematological parameters. Results: The result showed an elevation in liver parameters; ALT, ALP, AST, total bilirubin, conjugated bilirubin in the treatment groups compared to the control. Conversely, the concentration of Na+, Cl- and HCO3- revealed no significant difference compared to the control while urea and creatinine increased significantly. Haematological parameters showed increase in WBC, PCV, PLT in the treatments groups while RBC, Hb, MCV decreased. For lipid profile; Total cholesterol, TG, HDL and LDL increased significantly in the groups treated with mid and high dose DCF. Conclusion: The level of PSA was found to increase in all the treatment groups compared to the control. This result revealed that DCF-Potassium at high concentration can inter fare with the liver and kidney functions, lipid profile and haematological parameters as well as increasing PSA level. Thus, we conclude that persistent consumption of DCF can likely predispose to BPH.

Knowledge of investment regarding the characteristics of benefits and costs of mutual fund products is still very minimal and access to market information on the mutual fund is limited which can be an investment alternative that can be used by the Samarinda community. This Community Service Program aims to provide investment knowledge of mutual fund products through online media whose information can be accessed by every community, especially Samarinda. The PkM program was implemented in 5 sub-districts of welcome sub-districts and 5 sub-districts of Sungai Pinang sub-district on July 8 to August 18 2020 using the online / virtual face-to-face meeting method with online problem solving steps, namely the first step to provide investment knowledge education and introduction to mutual fund product characters, the second step is distributing online questionnaires to community respondents, the third step is processing the questionnaire data, and the fourth step is collecting empirical references and interpreting the observed data. The pandemic covid 19, this motion as investors turned the people of refracting life changed, his extensive and complex investment and the confidence to reach the fixed investment can be achieved .This research includes 268 respondents, the data processed with validity test, reliability test and hypotheses test with analysis 1-10 scale semantic, the independent variable obtained that investment 56,2 percent knowledge and confidence can explain the variable dependent of champion investment in the pandemic covid19 Samarinda Town Kalimantan east of Indonesian society.