Alcohol dependence has been showing a rising trend all over the world including India. Alcohol consumption has health and social consequences via intoxication, alcohol dependence and other biochemical effects of alcohol. Exposure and desensitization, thought-monitoring, relaxation, and acceptance, have all been suggested as potential active ingredients of mindfulness training which could help an individual to find new ways to behave by changing their thought process. Hence the present study was conducted with the aim to determine the effectiveness of vipassana meditation on psychosocial problems among adults with alcohol dependence syndrome. Pre-experimental research design was adapted with 30 participants who met the inclusion criteria was selected by convenience sampling technique. The demographic questionnaire was completed at the beginning of the study. Pre-test assessment on psychosocial problems was assessed using checklist. Vispasana meditation was administered to the participants for 10 days and post-test was conducted at the tenth day using same tool. The data were tabulated and analyzed by using descriptive and inferential statistics. Paired t test reveals that the administration of vipassana meditation was found to be effective in reducing the level of psychosocial problems of alcohol dependence symptoms among adults. The study findings concluded that vipassana meditation has great impact on reduction of psychosocial problems. The finding motivates to do more research in order to provide comprehensive care to the alcohol dependent related psychosocial problems.

Seed germination is the critical stage in plant's life cycle, assisting sapling development, survivorship, and population trends. Plants, as sessile life forms, are easily exposed to abiotic stresses like heat, salinity, cold, soil alkalinization, drought. The interaction of nano-materials with the plant, soil, and the holobiont systems is critical for understanding their behaviors within every complicated ecosystem. The use of nanoparticles has a beneficial impact on germinating seeds and also plant growth and development. Titanium based nanoparticles triggers the development of carbohydrates, which promotes rates of photosynthesis and plant growth. It is hoped that nanotech will provide long-term remedies by replacing conventional bulk fertilizers with nano-particulate counter parts that have excellent characteristics for overcoming current problems such as mineral bio-availability and absorption. Nano-priming could be practiced to seeds to preserve them during storage, enhance germination rate, germination synchronization, and plant growth, and also enhance resistance of crop to biotic and abiotic stressful conditions.

Teacher performance is very important in ensuring the achievement of school goals, it needs to be encouraged for better performance. However, this is not easy because many factors influence it. The purpose of this study was to analyze the direct and indirect effects of work motivation, job satisfaction and Organizational Citizenship Behavior (OCB) on teacher performance at SDN Murung Pudak District, Tabalong Regency. This research is a regression research with a quantitative approach which is formulated into a path analysis model. Based on the results of the study, the variable regression coefficient values were positive numbers such as work motivation (X1) with performance (Y) of 0.275, work motivation (X1) with Organizational Citizenship Behavior (OCB) (Z) of 0.433 , job satisfaction (X2) with performance teachers (Y) of 0.375, job satisfaction (X2) with Orgaizational Citizenship Behavior (OCB) (Z) of 0.435, Orgaizational Citizenship Behavior (OCB) (Z) with teacher performance (Y) of 0.269 , work motivation (X1) through organizational Citizenship Behavior (OCB) (Z) with teacher performance (Y) of 0.116 and job satisfaction (X2) through Organizational Citizenship Behavior (OCB) (Z) with teacher performance (Y) of 0.117. Therefore, this study can be concluded that there is a significant direct and indirect effect between work motivation, job satisfaction and Organizational Citizenship Behavior (OCB) on teacher performance.

Viruses are the group of infectious particles and some of them possess the more complex structures due to which their growth proliferated at the extreme level as compared to the bacterial infections. Pharmacokinetics of some drugs needed to further more in order to explore them in the medical events or sometimes drug research increase the chances of treatment of infectious disease during the course of replicating cycle. Among them, coronaviruses are appearing on different form of variants. These are Beta, Delta, and Omicron variants and each type have different sequence of the amino acids. Due to colonization of the virus particles in the particular tissues, many of the immune cells show response against variety of viral proteins. Severity of viruses attack to the cardiovascular systems causing the borne of different cardiovascular diseases. Different traditional methods for molecular diagnosis of infectious particles but not reliable, but through molecular sequencing of certain mutation associated with lungs tissues may evoke the viral spikes proteins. Due to severe attack on the lung tissues, blood rushes and flow increases in the form of infectious particles. Vaccinations and antibodies are used for control their growth but some of the necessary measures in order to control the viral infections.

Background: The coronavirus disease 2019 pandemic is an unprecedented situation. Mass vaccination is a considered a promising solution to combat this global health crisis. Different vaccine have used to control transmission of the disease. Some complications of this vaccine were reported including rare cases of vasculitis. We report a case of leucocytoclastic vasculitis following BNT162b2 corona virus vaccine. Case Presentation: A 42 year old man with no medical history or drug intake presented 3 days after the third dose of BNT162b2 vaccine an infiltrated purpura at the lower extremities, fever, asthenia and myalgia. At physical examination, multiple palpable indurated purpuric papules were present only on the lower extremities. Laboratory tests were normal. The skin biopsy revealed leucocytoclastic vasculitis. The direct immunofluorescence staining detected only fibrinogen deposition. Conclusion: Leucocytoclastic vasculitis is an exceptional vaccine side effect. The resemblance of the vaccine-induced spike proteins with human components is highly likely to produce pathological autoantibodies and vaccine-induced autoimmunity through molecular mimicry.

This research was conducted to find out how the planning, implementation, and follow-up of academic supervision of supervisors in an effort to improve the pedagogic competence of Islamic Religious Education teachers in the implementation of academic supervision of Islamic Religious Education at SMPN 1 Anjir Muara and SMPN 2 Anjir Muara, Barito Kuala Regency. The study used a qualitative research method which was conducted at SMPN 1 Anjir Muara and SMPN 2 Anjir Muara, Barito Kuala Regency. The subject of this research is the supervisor of Islamic Religious Education. As informants in this study were school principals and teachers of Islamic Religious Education. Data collection techniques used the methods of observation, documentation, and interviews. Checking the validity of the data used source triangulation techniques and methods. The data analysis technique was carried out with an interactive model consisting of: data collection, data reduction, data presentation, and drawing conclusions. The results of the study show that the implementation of academic supervision as a whole has been carried out using 10 indicators that have been determined through activities or actions in every job with all its professions which are always based on a serious attitude and a high work ethic that can improve teacher pedagogic competence of Islamic Religious Education.

This study aims to analyze the direct and indirect influence between the principal's transformational leadership, work culture and teacher work commitment on teacher performance at SMPN Banjarbaru City. This research is a descriptive correlation with a quantitative approach which is formulated into a path analysis model. The research population was 407 teachers from 14 schools and 202 respondents were taken as research samples using proportional random sampling technique. Collecting data using a questionnaire instrument and data analysis using descriptive analysis, classical assumption test, and hypothesis testing and path analysis. The conclusion of this study is that there is a significant direct relationship between transformational leadership, work culture and work commitment with teacher performance. There is an indirect relationship of transformational leadership through work commitment to the performance of Banjarbaru City Junior High School teachers. There is an indirect relationship between work culture through work commitment and the performance of SMPN Banjarbaru City teachers.

This study aims to analyze the direct and indirect relationship between teacher commitment, teacher discipline and work motivation with teacher performance at SMPN Kahayan District, Pulang Pisau Regency. The method used in this research is a correlational method with a quantitative approach which is formulated into a path analysis model. The research population was 248 teachers from 18 schools in 3 sub-districts and 153 respondents were taken as research samples as research samples using probability simple random sampling technique. Collecting data using a questionnaire instrument and data analysis using descriptive analysis, classical assumption test, hypothesis testing and path analysis. The conclusion of this study is that there is a significant direct relationship between teacher commitment, teacher discipline and work motivation with teacher performance. There is a direct relationship between teacher commitment and teacher discipline with work motivation, there is an indirect relationship between teacher commitment through work motivation and teacher performance at SMPN Kahayan District Pulang Pisau Regency and there is an indirect effect between teacher discipline through work motivation and performance at SMPN Kahayan District Pulang Regency Knife.

Nowadays, the construction of discourse system with Chinese characteristics is an important part of the comprehensive promotion of Chinese Characteristic Major-country Diplomacy. It is also an important way to shape a true, three-dimensional and comprehensive image of China and to coordinate the domestic and international situations. As our country pays more and more attention to building a national discourse system, discourse system with Chinese characteristics has gradually become a topic of eager attention by the majority of scholars. Using the content analysis method, this article analyzes the number, quality, hot spots, discipline distribution, author distribution and fund distribution of articles on discourse system with Chinese characteristics published in Peking University core journals and CSSCI journals of CNKI from 2011 to 2021, in order to reflect the research status and development trend of discourse system with Chinese characteristics in recent ten years, and to provide a reference for the study of discourse system with Chinese characteristics in the future. The results show that: (1) The research on discourse system with Chinese characteristics is highly valued by our country and scholars from all walks of life, and the research prospect is considerable. (2) The current research hotspots are mainly concentrated on the discourse system, socialism with Chinese characteristics, philosophy and social sciences with Chinese characteristics, and academic discourse systems, etc. (3) The discipline distribution of the research on discourse system with Chinese characteristics is mainly concentrated in multi-disciplinary fields such as Chinese politics and international politics, social science theories and methods, higher education, news and media, showing the potential of extensive integration of discourse system with Chinese characteristics research with other disciplines. (4) The country attaches great importance to the research on discourse system with Chinese characteristics, but the local support is insufficient. (5) The amount of research on discourse system with Chinese characteristics is considerable, but the quality is not good enough. The depth and breadth of the research on discourse system with Chinese characteristics need to be further expanded.

Different heavy salts accumulated in the soil causing the soil salinity and damage the biological processing occurring in plants such as photosynthesis and light reactions. Climate changes also promote the accumulation of heavy metals by promoting the chemicals substances in the leaves and roots cells that causing the chlorosis. Coal combustion release the large amount of mercury metals that acting as toxic for the plants. There is need to design the biological and mechanical processing the removal of salts and toxic wastes from surfaces in such a way that no eruptions of plant materials occur at the surfaces. Nanotechnology employed the nanoparticles to capture the toxic metals through biological and chemical process that is more reliable and less expensive. A large variety of nanoparticles in the form of nanobased graphene oxides, graphite oxides and CNT, mesoporous silica materials have been used for controlling the pollution caused by heavy metals. These nanoparticles are compatible for the plant growth by suppressing the crop diseases by acting directly on phytopathogens. Therefore, it is reliable for controlling the risk of environmental pollution caused by heavy metals.

Dermatofibrosarcoma Protuberans (DFSP) is an uncommon soft tissue tumor that involves the dermis, subcutaneous fat, and in rare cases, muscle and fascia. It represents less than 0.1% of all tumors, but is considered to be the most common skin sarcoma. We present one such case where histopathology and immunohistochemistry helped clinch the diagnosis .DFSP has a high rate of recurrence but a low rate of metastasis. Wide surgical excision is the cornerstone of treatment for DFSP.

The review was undertaken to evaluate the development of COVID-19 vaccines in India. This review highlights the different types of platforms to develop COVID-19 vaccines, about the safety and efficacy of available COVID-19 vaccines and various strategies applied by government to increase vaccination doses in India. The analysis was done based on data extraction from online electronic databases and utilized all the data available from the WHO, CDC, Indian Government and State Government official portal for COVID-19 vaccines. Search engines like Google Scholar and PubMed were thoroughly searched for keywords like term “COVID-19 vaccines [AND] India, COVID-19 vaccine development [AND] India”, “COVID-19 vaccine Safety and efficacy [AND] India”, “COVID-19 vaccination [AND] India”. Forty articles were searched based on titles, 10 were excluded after reading the abstract. After scrutinizing all retrieved data only ten highly relevant articles were included in the final analysis. Data available from official portal for COVID-19 vaccination daily updates were collected and used as source data for the current study. Hence the data given in the study completely available from the public source. Despite significant increases in the number of well-trained health personnel, facilities, and sophisticated medical equipment, as well as increased access to and sharing of up-to-date scientific and medical information in many countries, the COVID-19 pandemic has proven that pandemic preparedness remains a major global issue that must be addressed urgently.

A well-developed banking system is prerequisite for a fast-growing economy. The introduction of financial instruments is a collaborative effort that pits the results of analysis of the banking sector's development and impact on the economy against basic regulatory standards and approaches to state regulation of the financial system's development and banking subsystem. Banking sectors, according to economic literature, play an intermediation role by enabling money transfers between fund-suppliers and fund-demanders. This can be accomplished by attracting savings and then directing those funds into loans to fund various economic activities, resulting in economic growth (EG). Every bank has its own internal component that affects financial performance in a particular way the more efficient a country's financial sector develops, the more likely its limited resources will be channeled to the most productive use. Openness in the banking sector may have a direct impact on growth by enhancing access to financial services and indirectly by improving the efficiency of financial intermediaries, both of which lower the cost of financing and, as a result, encourage capital accumulation and economic growth. A variety of macroeconomic links, notably the one between financial development and long-run growth, have been studied using cross-country regressions. Microeconomic explanation differs from the traditional perspective, which sees financial intermediaries as a bridge between borrowers and lenders' differing interests in terms of the size, maturity, and risk of a financial investment.

Background: Retropulsion and stone fragment migration is a problem with lithotripsy especially for proximal and mid-ureteric calculi during ureteroscopy, leading to increased operative time, costs, and additional procedures. To overcome this drawback, many strategies have been developed, one of which is the use of anti-retropulsion devices like the stone cone. Objective: To describe our initial experience with the use of the stone cone during holmium laser lithotripsy in a patient with proximal and mid-ureteric stone for preventing retropulsion. Method: This is a retrospective study carried out on six consecutive patients with proximal with uncommon proximal ureteric stone over a 2year period ureteric stone. TPatients with distal ureteric stone were excluded. The Boston Scientific Stone Cone Nitinol Retrieval Coil was passed beyond the stone and deployed under fluoroscopy to prevent proximal stone and fragment migration. Holmium laser lithotripsy was then carried out. The fragments were removed with graspers and the stone cone was then removed. A double J stent was passed in all cases for about two to a month week and removed. The total operating time was noted. The data on the patient’s age, sex, stone size, Hounsfield, and stone clearance was analyzed using SPSS version 20. Results: There were six patients, five male, and one female with a mean age of 37.5years with an age range between 27 – 54years. The stone sizes ranged from 7-15mm with a mean dimension of 11.17mm. The Hounsfield of the stones ranged from 539 to 1171HU with a mean of 765.5HU. The operating time ranged from 55 – 90minutes with a mean of 67.5minutes. None had retropulsion with 100% stone clearance. Conclusion: The stone cone is a safe device and is useful during ureteroscopy and lithotripsy for mid-and proximal ureteric stone in preventing retropulsion and improving stone clearance.

The introduction of jazz and blues in the United States of America influenced the works of Afro American writers both in content and form. These jazz and blues musical songs were used as mediums to protest against racism, class, gender and other inhuman practices meted on the blacks in the United States. Although these songs were not formally written, they became a source of inspiration for writers afterwards in terms of themes and style. The later writers who changed to formal literature borrowed from the themes and styles of these jazz and blues musicians. This paper is signicant because it has examined the thematic preoccupation of June Jordan’ Directed by Desires and Richard Wright's novel, Native Son. Findings show that both writers were thematically and stylistically influenced by the jazz and blues era of art in Af ro American Literature. Data for this essay was collected via qualitative research methodology, while the postcolonial theory was adopted for analysis. The paper submits that themes of racism, class, gender and protest were features of the jazz and blues era which later writers modelled their works after.