Piper guineense (uziza) leaves may have therapeutic input on male infertility caused by Lead exposure. This study investigated the antioxidant activities of the ethanolic extract of Piper guineense leaves (EEPL) on lead-induced testicular toxicity in rats. Twenty male wistar rats (150-200g) were divided into 4 groups consisting of 5 rats each. Control received 1ml of distilled water, lead only received 150mg/kg of lead, low dose received 150mg/kg of lead + 300mg/kg of EEPL, high dose received 150mg/kg of lead + 600mg/kg of EEPL. Administration was done orally for 14 days and then sacrificed. Blood was collected and analysed for serum testosterone and testes were harvested and homogenised for testicular antioxidant enzymes and zinc levels. Data was analysed for ANOVA using Graph Pad Prism 5. Lead exposure negatively affected the antioxidant enzymes, testosterone and zinc levels. Administration of EEPL significantly (p<0.05) increased the testosterone and zinc levels in a dose dependent manner. EEPL also significantly (p<0.05) increased the testicular Superoxide dismutase, Catalase, and Glutathione peroxidase levels and significantly decreased the testicular Malondialdehyde levels. Piper guineense leaves ameliorate testicular oxidative stress damage induced by lead toxicity.

Urinary tract infection is the attack of a tissue of the urinary tract by one or more micro-organisms. It is a major public health problem. The objective of this work is to propose, based on updated data, the microbial ecology of urinary tract infection at the Avicenne Military Hospital in Marrakech, and to follow the antibiotic sensitivity profile of uropathogenic bacteria. This is a retrospective descriptive study over 4 years from January 2014 to December 2018, which was conducted on urinary cytobacteriological examinations from hospitalized patients and outpatients, treated at the microbiology laboratory of the Military Hospital Avicenne of Marrakech. Of the 17607 ECBUs that were examined, the diagnosis of urinary tract infection was retained in 2349 (13%). 75% of the ECBUs came from hospitalized patients and 25% from outpatients, with a sex ratio of 1.1. The analysis of the ECBU showed that Enterobacteriaceae constituted 80% of the positive urine isolates, with a predominance of Escherichia coli (62%), followed by Klebsiella pneumoniae (13%). The reading and interpretation of the antibiograms showed that Escherichia coli was resistant to aminopenicillin associated with clavulanic acid in 51% of the cases against 55% for Klebsiella pneumoniae. The resistance of enterobacteriaceae to fluoroquinolones is about 33% for Escherichia coli, 30% for Klebsiella spp, while for the Trimmethoprim+Sulfamethoxazole combination more than half of the strains were resistant. On the other hand, aminoglycosides still have a good activity profile on enterobacteriaceae. The prevalence of BMR is 6.5%, represented by enterobacteriaceae producing extended spectrum betalactamases (ESBL) isolated in 89% of cases, with a predominance of Escherichia coli (52%) followed by klebsiella pneumoniae (22%) and Enterobacter cloacae (16%). Then the ceftazidime-resistant Pseudomonas aeruginosa (PARC) occupies the 2nd place with 5%, and finally methicillin-resistant Staphylococcus aureus (MRSA) and imipenem-resistant Acinetobnacter baumanii (ABRI) which occupy the 3rd place with rates at 3%. These BMR constitute a worrying problem, hence the need for rigorous application of hygiene rules and rational prescription of antibiotics. The knowledge of bacteriological profiles and the use of targeted antibiotic susceptibility testing will allow a management adapted to each hospital context.

Different heavy salts accumulated in the soil causing the soil salinity and damage the biological processing occurring in plants such as photosynthesis and light reactions. Climate changes also promote the accumulation of heavy metals by promoting the chemicals substances in the leaves and roots cells that causing the chlorosis. Coal combustion release the large amount of mercury metals that acting as toxic for the plants. There is need to design the biological and mechanical processing the removal of salts and toxic wastes from surfaces in such a way that no eruptions of plant materials occur at the surfaces. Nanotechnology employed the nanoparticles to capture the toxic metals through biological and chemical process that is more reliable and less expensive. A large variety of nanoparticles in the form of nanobased graphene oxides, graphite oxides and CNT, mesoporous silica materials have been used for controlling the pollution caused by heavy metals. These nanoparticles are compatible for the plant growth by suppressing the crop diseases by acting directly on phytopathogens. Therefore, it is reliable for controlling the risk of environmental pollution caused by heavy metals.

Viruses are the group of infectious particles and some of them possess the more complex structures due to which their growth proliferated at the extreme level as compared to the bacterial infections. Pharmacokinetics of some drugs needed to further more in order to explore them in the medical events or sometimes drug research increase the chances of treatment of infectious disease during the course of replicating cycle. Among them, coronaviruses are appearing on different form of variants. These are Beta, Delta, and Omicron variants and each type have different sequence of the amino acids. Due to colonization of the virus particles in the particular tissues, many of the immune cells show response against variety of viral proteins. Severity of viruses attack to the cardiovascular systems causing the borne of different cardiovascular diseases. Different traditional methods for molecular diagnosis of infectious particles but not reliable, but through molecular sequencing of certain mutation associated with lungs tissues may evoke the viral spikes proteins. Due to severe attack on the lung tissues, blood rushes and flow increases in the form of infectious particles. Vaccinations and antibodies are used for control their growth but some of the necessary measures in order to control the viral infections.

This study aims to analyze the direct and indirect influence between the principal's transformational leadership, work culture and teacher work commitment on teacher performance at SMPN Banjarbaru City. This research is a descriptive correlation with a quantitative approach which is formulated into a path analysis model. The research population was 407 teachers from 14 schools and 202 respondents were taken as research samples using proportional random sampling technique. Collecting data using a questionnaire instrument and data analysis using descriptive analysis, classical assumption test, and hypothesis testing and path analysis. The conclusion of this study is that there is a significant direct relationship between transformational leadership, work culture and work commitment with teacher performance. There is an indirect relationship of transformational leadership through work commitment to the performance of Banjarbaru City Junior High School teachers. There is an indirect relationship between work culture through work commitment and the performance of SMPN Banjarbaru City teachers.

An increase in demand for concrete to meet global needs has been accompanied by an increase in global concerns due to an increase in demand for the non-renewable resources that are and comprise the constituents of concrete. To address these concerns and mitigate the impact of their depletion, researchers have investigated the intrinsic properties of a wide range of available materials and assessed their contribution when mixed with concrete. This paper presents the findings of an experimental study that was carried out to assess the structural response of concrete beams made with river gravel as coarse aggregate. Six reinforced beams (100 x 150 x 1100 mm) and six cubes were cast to investigate the specimens' flexural and compressive behavior. The failure modes, bending, and shear capacity were investigated in this study. According to the findings of the study, river gravel used as coarse aggregate in concrete has a roughly equivalent or slightly lower structural performance than conventional coarse aggregate, indicating the feasibility of river gravel as coarse aggregate for building construction.

Background: The coronavirus disease 2019 pandemic is an unprecedented situation. Mass vaccination is a considered a promising solution to combat this global health crisis. Different vaccine have used to control transmission of the disease. Some complications of this vaccine were reported including rare cases of vasculitis. We report a case of leucocytoclastic vasculitis following BNT162b2 corona virus vaccine. Case Presentation: A 42 year old man with no medical history or drug intake presented 3 days after the third dose of BNT162b2 vaccine an infiltrated purpura at the lower extremities, fever, asthenia and myalgia. At physical examination, multiple palpable indurated purpuric papules were present only on the lower extremities. Laboratory tests were normal. The skin biopsy revealed leucocytoclastic vasculitis. The direct immunofluorescence staining detected only fibrinogen deposition. Conclusion: Leucocytoclastic vasculitis is an exceptional vaccine side effect. The resemblance of the vaccine-induced spike proteins with human components is highly likely to produce pathological autoantibodies and vaccine-induced autoimmunity through molecular mimicry.

This research was conducted to find out how the planning, implementation, and follow-up of academic supervision of supervisors in an effort to improve the pedagogic competence of Islamic Religious Education teachers in the implementation of academic supervision of Islamic Religious Education at SMPN 1 Anjir Muara and SMPN 2 Anjir Muara, Barito Kuala Regency. The study used a qualitative research method which was conducted at SMPN 1 Anjir Muara and SMPN 2 Anjir Muara, Barito Kuala Regency. The subject of this research is the supervisor of Islamic Religious Education. As informants in this study were school principals and teachers of Islamic Religious Education. Data collection techniques used the methods of observation, documentation, and interviews. Checking the validity of the data used source triangulation techniques and methods. The data analysis technique was carried out with an interactive model consisting of: data collection, data reduction, data presentation, and drawing conclusions. The results of the study show that the implementation of academic supervision as a whole has been carried out using 10 indicators that have been determined through activities or actions in every job with all its professions which are always based on a serious attitude and a high work ethic that can improve teacher pedagogic competence of Islamic Religious Education.

Nowadays, the construction of discourse system with Chinese characteristics is an important part of the comprehensive promotion of Chinese Characteristic Major-country Diplomacy. It is also an important way to shape a true, three-dimensional and comprehensive image of China and to coordinate the domestic and international situations. As our country pays more and more attention to building a national discourse system, discourse system with Chinese characteristics has gradually become a topic of eager attention by the majority of scholars. Using the content analysis method, this article analyzes the number, quality, hot spots, discipline distribution, author distribution and fund distribution of articles on discourse system with Chinese characteristics published in Peking University core journals and CSSCI journals of CNKI from 2011 to 2021, in order to reflect the research status and development trend of discourse system with Chinese characteristics in recent ten years, and to provide a reference for the study of discourse system with Chinese characteristics in the future. The results show that: (1) The research on discourse system with Chinese characteristics is highly valued by our country and scholars from all walks of life, and the research prospect is considerable. (2) The current research hotspots are mainly concentrated on the discourse system, socialism with Chinese characteristics, philosophy and social sciences with Chinese characteristics, and academic discourse systems, etc. (3) The discipline distribution of the research on discourse system with Chinese characteristics is mainly concentrated in multi-disciplinary fields such as Chinese politics and international politics, social science theories and methods, higher education, news and media, showing the potential of extensive integration of discourse system with Chinese characteristics research with other disciplines. (4) The country attaches great importance to the research on discourse system with Chinese characteristics, but the local support is insufficient. (5) The amount of research on discourse system with Chinese characteristics is considerable, but the quality is not good enough. The depth and breadth of the research on discourse system with Chinese characteristics need to be further expanded.

Background: Practicing in trauma unit can strengthen nurses’ knowledge about the association of past trauma and the impact of trauma on the patient’s current mental illness. An aim of this debate is to avoid potentially re-traumatizing a patient during their episode of care. This educational discussion can provide nurses with content that describes the interplay of neurological, biological, psychological, and social effects of trauma that may reduce the likelihood of re-traumatization. Although multidisciplinary environments, the translation into clinical practice by nurses working in emergency departments (EDs) is unknown. However, before ED nurses can begin to practice, they must first be provided with meaningful and specific education about their role. Therefore, the aim of this debate was to evaluate the role and emergency management skills of ED nurses. Methods: This debate was conducted as exploratory research with a descriptive study design. Quantitative data were collected with an 18-item pre-education and post-education questionnaire. Results: A total of 34 ED nurses participated in this education discussion. There was meaningful change (p < 0.01, r ≥ 0.35) in 9 of the 18-items after discussion. The debate was based on the perceived effectiveness to evaluate the role and emergency management skills of ED nurses. Conclusion: Emergency department nurses became more informed of the interplay of trauma on an individual’s mental health. However, providing care to trauma patients in an ED setting was a considerable challenge primarily due to time constraints relative to the day-to-day. ED environment and rapid turnover of patients with potentially multiple and complex presentations. Despite this, nurses played a good role to reduce the likelihood of re-traumatization.

Alcohol dependence has been showing a rising trend all over the world including India. Alcohol consumption has health and social consequences via intoxication, alcohol dependence and other biochemical effects of alcohol. Exposure and desensitization, thought-monitoring, relaxation, and acceptance, have all been suggested as potential active ingredients of mindfulness training which could help an individual to find new ways to behave by changing their thought process. Hence the present study was conducted with the aim to determine the effectiveness of vipassana meditation on psychosocial problems among adults with alcohol dependence syndrome. Pre-experimental research design was adapted with 30 participants who met the inclusion criteria was selected by convenience sampling technique. The demographic questionnaire was completed at the beginning of the study. Pre-test assessment on psychosocial problems was assessed using checklist. Vispasana meditation was administered to the participants for 10 days and post-test was conducted at the tenth day using same tool. The data were tabulated and analyzed by using descriptive and inferential statistics. Paired t test reveals that the administration of vipassana meditation was found to be effective in reducing the level of psychosocial problems of alcohol dependence symptoms among adults. The study findings concluded that vipassana meditation has great impact on reduction of psychosocial problems. The finding motivates to do more research in order to provide comprehensive care to the alcohol dependent related psychosocial problems.

A well-developed banking system is prerequisite for a fast-growing economy. The introduction of financial instruments is a collaborative effort that pits the results of analysis of the banking sector's development and impact on the economy against basic regulatory standards and approaches to state regulation of the financial system's development and banking subsystem. Banking sectors, according to economic literature, play an intermediation role by enabling money transfers between fund-suppliers and fund-demanders. This can be accomplished by attracting savings and then directing those funds into loans to fund various economic activities, resulting in economic growth (EG). Every bank has its own internal component that affects financial performance in a particular way the more efficient a country's financial sector develops, the more likely its limited resources will be channeled to the most productive use. Openness in the banking sector may have a direct impact on growth by enhancing access to financial services and indirectly by improving the efficiency of financial intermediaries, both of which lower the cost of financing and, as a result, encourage capital accumulation and economic growth. A variety of macroeconomic links, notably the one between financial development and long-run growth, have been studied using cross-country regressions. Microeconomic explanation differs from the traditional perspective, which sees financial intermediaries as a bridge between borrowers and lenders' differing interests in terms of the size, maturity, and risk of a financial investment.

This research work investigates to select the appropriate portion like top, middle, bottom for both Tossa and White jute for suitable applications such as reinforcement, blending yarn, and diversified jute products. The fundamental properties of Tossa and White such as bundle strength, fineness, breaking twist, and whiteness (%) were studied. It was observed that the maximum strength found at the bottom portion for both Tossa and White were 10.35 lbs/mg, 10.08 lbs/mg respectively. The results revealed the higher breaking twist and whiteness (%) at the middle portion for both Tossa and White jute were 42.65, 36.75, 42.5%, 39% respectively. The better fineness found that at the top portion of Tossa and White jute were 36.15, 31.05 respectively.

Dermatofibrosarcoma Protuberans (DFSP) is an uncommon soft tissue tumor that involves the dermis, subcutaneous fat, and in rare cases, muscle and fascia. It represents less than 0.1% of all tumors, but is considered to be the most common skin sarcoma. We present one such case where histopathology and immunohistochemistry helped clinch the diagnosis .DFSP has a high rate of recurrence but a low rate of metastasis. Wide surgical excision is the cornerstone of treatment for DFSP.

In order to reveal how female figures with power construct their social identity through discourse, this paper analyzes the discourse pattern of female anti-stereotype in Mrs. Thatcher’s two speeches through data statistics from the theoretical perspective of gender construction. It is concluded that the anti-stereotype discourse pattern still reflects the social construction with male discourse as the power center, and the phenomenon of gender discrimination still exists.