In PIM process, the molding stage is a critical step for the fabrication of sound parts without cracks and distortions. So, this step requires specific rheological behavior. Rheological analysis can be made to quantify the stability of the PIM feedstock during molding process. In this study, an experimental rheological study has been performed to evaluate the effect of composition binder system on the stability of titanium alloy powder injection molding (MIM) feedstock in term of shear sensitivity and activation energy. The rheology properties of feedstock were measured via capillary rheometer machine. The viscosity of feedstocks was measured at temperature of 120C, 130C, 140C and 150C under different five (5) different constant load at 20N,30N,40N,50N and 60N respectively. The results show that the addition of binder component which possess low molecule weight has reduce flow behavior index value and increase flow activation energy value of feedstock. However, the feedstock produced will get a problem such powder-binder separation and high residue stress which will defect the molded part component. The formulation binder system PEPS 4060 is the best feedstock for titanium alloy MIM process because it has moderate value of flow sensitivity index and flow activation energy value and higher value for mold ability index.

Osler-Weber-Rendu syndrome (OWRD) is a rare vascular dysplasia of genetic origin and of autosomal dominant transmission, the pathophysiology of which involves the vascular endothelial growth factor (VEGF), a major growth factor of angiogenesis. Bevacizumab is an anti-VEGF monoclonal antibody that has demonstrated its interest in this indication. Two patients, with a personal and familial history of haemorrhagic syndrome, who had an OWRD detected in recurrent epistaxis, cutaneous-mucosal telangiectasia, and complicated visceral arteriovenous malformations with an iron deficiency anemia. Due to the persistence of the symptomatology despite a transfusion support, the treatment with bevacizumab was started and allowed a favorable outcome. Bevacizumab appears to be very well tolerated and represents a therapeutic advance in OWRD.

The existence of the internet not only has positive impacts, but also has negative impacts, one of which is the rampant hate speech that is spread through social media. The government then issued Law No. 11 of 2008 concerning Electronic Information and Transactions as amended by Law No. 19 of 2016, which regulates the criminalization of hate speech conducted via electronic media. Nonetheless, even though there have been criminal threats against acts of hate speech through cyberspace, the number of cases of hate speech that are handled by the police has actually increased from year to year. The purpose of this paper is to find out how the influence of social changes in the criminalization of hate speech through electronic media and the effectiveness of criminalization of hate speech through electronic media as an effort to tackle the rise of hate speech in cyberspace. This research uses normative legal research method. The results of this study explain that social changes related to the way of sharing information via electronic media have a real impact on applicable law in Indonesia with the existence of regulations regarding the criminalization of hate speech through electronic media. However, since the enactment of this regulation, the number of acts of hate speech through electronic media has increased from year to year. Therefore, the criminalization policy must pay attention to the principle of subsidiarity, meaning that criminal law must be placed as a last resort in overcoming crimes using a penal instrument, not as the main effort. Other efforts are needed that should be prioritized apart from punishing the perpetrators of criminal acts.

The development of artificial bone using alumina and Nsu clay was carried out in order to determine the effect of Al2O3.2SiO2.2H2O on the properties of locally developed Al2O3-based artificial bone. The raw materials were used to formulate seven samples (A - G) and shaped using casting method. The physical properties investigated after sintering of the samples at 1400oC indicated that samples A-G had linear shrinkage ranging from 3.17% - 3.98% with percentage porosity ranging from 4.78% - 4.51% respectively. The result of bulk density of the samples ranges from 2.6g/cm3 - 4.20g/cm 3 with corresponding compressive strength ranging from 424.5MPa - 489.1MPa. It was discovered that the lower the percentage of alumina content in the composition, the higher the bulk density, linear shrinkage and compressive strength while the lower the porosity of the samples, vice versa. Moreover, sample D of the artificial bone gave the most favourable result in view of the stated properties above. Therefore sample D can be used for production of artificial bone. However, the investigated physical properties gave results that are acceptable for a standard artificial bone, this product is an archetype, therefore, it requires a clinical/medical compatibility test before it can be put to use.

COVID-19 pandemic affected the entire education system including dentistry. Dental students were affected psychologically because of the highest risk due to the nature of their clinical training which includes working in the oral cavity using aerosol-generating equipment. The aim of this review is to present the challenges faced by the dental students.

Thyroid adenomas (TA) are benign tumors, but there is a 20% possibility of malignant transformation. The distinguishing between the TA and thyroid cancer (TC) is tricky, therefore new TA biomarkers are needed. Furthermore, the role of trace elements (TE) in etiology and pathogenesis of TA is unclear. The aim of this exploratory study was to examine the content of ten trace elements (TE): silver (Ag), cobalt (Co), chromium (Cr), iron (Fe), mercury (Hg), rubidium (Rb), antimony (Sb), scandium (Sc), selenium (Se), and zinc (Zn) in the normal and adenomatous thyroid. Thyroid tissue levels of TE were prospectively evaluated in 46 patients with TA and 105 healthy inhabitants. Measurements were performed using non-destructive instrumental neutron activation analysis with high resolution spectrometry of long-lived radionuclides. Tissue samples were divided into two portions. One was used for morphological study while the other was intended for TE analysis. It was found that in adenomatous thyroid content of Ag, Cr, Hg, and Zn were significantly higher than in normal gland tissues. Thus, it is possible to suppose that the considerable changes in TE contents in the adenomatous transformed tissue of thyroid can be used as TA biomarkers.

One of the things that are protected for the benefit of humans is to maintain offspring. For this reason, Islam regulates marriage and forbids adultery, stipulates who should not be married, how marriage is carried out, what conditions must be met, and how is it legal so that the children that are born from that relationship can be considered legitimate and become legal descendants of their fathers. This study aims to analyze the position of the principle of monogamy in the Indonesian Law Number 1 of 1974 on Marriage by analyzing the application of the principle of monogamy in Law Number 1 of 1974 to reconstruct this law based on justice value. This research is a normative-legal type of research that is used to examine the function of a norm that lays the law as an instrument that regulates and controls society. The approach used in this research is conceptual, a statute approach, a philosophical approach, and a comparative approach. The analysis used in this research is descriptive-qualitative. The result shows that the marriage in Law Number 1 of 1974 which has been used so far has not fulfilled a sense of justice, especially for husbands who want to practice polygamy even though the wife has been permitted to do polygamy. Article 2 paragraph (2) provides special conditions for husbands who will have polygamy, namely permission from the court, even though permission from the first wife is already owned. This is certainly a burden for the husband because he has to deal with the court which of course requires time, money, and energy. In addition, the court's participation in granting permission for polygamy according to the author is a form of court intervention in other people's household affairs.

The performance and emission characteristics of a stationary four-cylinder, four-stroke, compression ignition (CI) diesel engine have been studied at 2000 rpm with pure diesel and watermelon seed oil methyl ester (WOME)-diesel (D80) blends with the additives acetoacetic ester, CuO and CuSO4 nanoparticles. A three-level factorial design was used to determine the quantity of WOME and the additives mixed with D80 in the experimental runs. The emission (H2S, NO2, CO and exhaust gas temperature (EGT)) and performance (fuel consumption (FC), brake specific fuel consumption (BSFC) and brake thermal efficiency (BTE)) properties were very much improved above WOME20D80. The emission properties were also better than diesel, except NO2 that was higher by 6.3 %. The performance properties were much better than WOME20D80 but not as good as diesel. Compared with diesel FC was 11.4 % higher, BSFC 11.4% higher and BTE was 4.3 % lower. These emission and performance values are better than most of what had been reported in the literature; the acetoacetic ester provided additional oxygen to ease combustion. The experimental data have been fitted to a second-order polynomial equation and subjected to analysis of variance leading to some equations that may help predict the emission and performance properties of CI engines.

Objectives: To explore whether work-related value influence nurses job satisfaction among Saudi Nurses at Major Tertiary Hospital. Methods: Used a descriptive correlational research design was used. The study was conducted in all in-patient and Outpatient, and critical care units at the tertiary hospital. A convenience Sampling Technique was used. Data were collected through a self-reported questionnaire comprising demographic characteristics, a work value questionnaire, and a job satisfaction survey. Frequency, Percentage, Mean, Standard Deviation, and Pearson Product Moment Correlational Coefficient were used as the statistical tools in treating the data gathered. Results: One hundred thirty Saudi nurses participated; most of them were females working in the tertiary hospital. Respondents are working for more than five years in the hospital. Moreover, Saudi nurses are highly educated, more than 40 % are holding with a BSc, and most nurses at tertiary hospital in Riyadh have stayed in their current position. Results revealed that the respondents moderately agreed with the work values as perceived by Saudi Nurses and were slightly satisfied concerning their job satisfaction. A positive association between work values and nurses' job satisfaction is significantly related to work values and job satisfaction. Conclusions: The work value was positively associated with nurses' job satisfaction. Leaders should pay more attention to create positive work value to increase job satisfaction for nurses and increase their stay.

The hypomineralized enamel lesions have 20% less mineral content, substantially reduced calcium and phosphorus ratio, and an increased carbon content which increases the likelihood of demineralization. The application of remineralizing agents on these lesions have been tried. In the present pilot study, to assess the change in mean fluorescence after the application of self-assembling peptide (SAP) on hypomineralized enamel lesions on ten MIH-affected incisors using laser fluorescence. After a single application of SAP, there was a decrease in the mean fluorescence score record with Diagnodent at two-time intervals i.e., baseline and one-month post-application. Thus, it can be concluded that the SAP application could use as a viable treatment option.

Age related stereotypes have greatly influenced the availability of employment opportunities for older women as well as their representation in different fields of work. One such field of work is the fashion industry, where ageism has been rampant, as many women above the age of 40 have been neglected and feel unrepresented. In this paper, different dimensions of ageism and how they affect the employment as well as the representation of older women in the fashion industry have extensively been discussed and analyzed. It is estimated that about 2 billion people, including women, around the world are to be aged over 60 by the year 2050, and hence, it is necessary to put an end to age related discrimination, stereotypes and prejudices [i].

The health challenges of students’ in tertiary institution have become imperative that increase attention be given to the method of health care delivery. The major purpose of the research is to develop a preliminary mobile health system (mHealth) for students in tertiary institutions. In this research, the waterfall model of software development methodology was adopted in developing a user friendly, web based, and mobile health system. The mHealth system developed has two interfaces: Students and Admin interface. The system has the ability to diagnose diseases, proffer treatments, give health advice and book appointment for students by assigning username and password to every student after registering with the Admin. Since increase utilization of mobile technology by tertiary institution students has been observed in recent times, it is expected that this mHealth system will address problem such as long queues, ensure prompt treatment and problems associated with the tertiary institution social health insurance programme (TISHIP).

This study was conducted to analyze the profitability of Aman rice Binadhan-17 producing farmers in Sunamganj, Rangpur, Gopalganj, Pabna and Magura districts of Bangladesh. This study was based on primary data which were collected from 200 Binadhan-17 producing farmers. In the sampled areas data were collected through pre-designed interview schedule from November-December, 2019 for achieving the purpose. In the study, costs and return analysis were done on both cash cost and full cost basis for estimating profitability. The cultivation of Binadhan-17 was profitable from the viewpoint of the farmers. The study found that Binadhan-17 production is profitable. The average net return per hectare was Tk. 34207.56. The net return was highest in Rangpur (Tk. 38536.88/ha) followed by Magura (Tk. 36091.84/ha), Gopalganj (Tk. 35783.18/ha), Pabna (Tk. 32345.11/ha) and Sunamganj (Tk. 28280.80/ha) respectively. Benefit cost ratio was 1.47 and 2.17 on full cost and cash cost basis implying that the Binadhan-17 cultivation at farm level was profitable. Cobb-Douglas production function was chosen to determine the factor affecting gross return of Binadhan-17 production. All of the factors namely, human labour cost, power tiller cost, seed cost, fertilizer cost and insecticides cost were statistically significant and positive. The regression coefficients of irrigation cost for Binadhan-17 under all areas were positive but not significant. The farmers in the study areas encountered some constraints to Binadhan-17 production. The first ranked constraint was unavailability of seeds in all areas (84%). Other constraints were lack of training (64%), lack of technical know-how (38%), lack of capital (30%), lack of storage facility (17%), natural calamities (14%) and low education level of farmers (10%). The economic return of Binadhan-17 production encouraging to the farmer’s for more cultivation.

Background: Dengue is a tropical disease caused by dengue virus (DENV). It is one of the most significant arthropod-borne viral infections. Objectives: The aim of the current study was to characterize epidemiological, laboratory markers of dengue infection during the recent epidemic in Lahore. Methods: During the prospective laboratory based observational study, 1,082dengue suspected cases were haematological examined. CBC tests were conducted for the confirmation of dengue infection due to decrease rate of platelets count. Data regarding the laboratory features, platelet count tests were also recorded for the dengue positive patients. Results: Out of total samples 300 cases including were223 (74.3%) were male and 77 (25.6%) were female detected positive for the dengue infection. In the dengue positive patients, the highest prevalence was observed in the age group41-50 years, 76(25.3%) followed age group11-20years, 28(9.3%), 31-40 years, 37 (12.3%), 51-60 years 34(11.3%), 61-70 years, 29(9.6%), 71-80 years, 25 (8.3%), 0-10 years are 9(3%). The highly affected area in District Lahore was Johar Town block B 61(20.3%) followed by Multan chungi (17%), Ewan town and Johar town block A are 34 (11.3%), Mustafa Town 29(9.6%), Gulberg 27 (9%), Shadman 24(8%), Johar Town block D 21(7%) and Iqbal town 19(6.3%). Conclusion: The highly affected area in district Lahore was found Johar town block B. Therefore, the health department should take actions by educating the public about basic cleanliness of the environment. The community should be encouraged to participate in the control of such vector based diseases/infections.

Diabetes Mellitus type 2 is said to be one of the complex diseases which is caused by complex interplay between genetic, epigenetic and environmental factors, while the major environmental factors, i.e., diet and physical activity level are well known, but the challenge is to identify the genetic factors involves in it. NGS (next generation sequencing) and GWAS (Genome Wide association studies) have led to technical development of genetic variants risked and protection of Type 2 Diabetes Mellitus. NGS which shows the amount of gene which has been expressed and there arrangement of nucleotide bases in the gene fragment which code for protein, also some genes , or a copy of gene which has lost the ability to produce a functional protein, may be due to mutation or inaccurate duplication in the sequence which are termed as Pseudo gene. These expressions of pseudo gene can occur due to SNP’s (Single Nucleotide Polymorphism) are DNA sequence variant that occur when a single nucleotide (A, T, C or G) in the genome sequence altered.