Background: Gbogbonise Epa Ijebu is a commercially sold native concoction in South-West, Nigeria, with the potential of curing many ailments as claimed by the manufacturer and vendors. This study investigated the antimicrobial quality and efficacy of Gbogbonise Epa Ijebu. Materials and Methods: A total of 20 samples of the herbal remedy were purchased from local vendors in Ilishan-Remo Community of Ogun State, Nigeria and were assessed for their microbiological quality using standard microbiological methods. Also, the efficacy of the herbal remedy was tested against some selected uropathogens using the Punch-hole agar diffusion method. Data generated were analyzed using the Instant GraphPad software package and P value <0.05 was considered statistically significant. Results: The outcome of the study shows that half (50%) of the herbal remedy samples examined were sterile, while the other half (50%) were contaminated with a microbial count of <10 CFU/mL. The microbial isolates recovered from the herbal remedy include: Staphylococcus aureus (8.3%), Coagulase negative Staphylococcus (75%) and Microsporium spp (16.7%). Assessment of the antimicrobial potential of the herbal remedy show that the test herbal remedy had strong inhibitory activity against Staphylococcus aureus (17±0.6 mm), Escherichia coli (16.3±0.3 mm), Pseudomonas aeruginosa (16.3±0.3 mm), Klebsiella pneumoniae (15±0.6 mm) and Proteus mirabilis (14±0.8 mm), except Candida albican, at a concentration of 200 mg/mL. The combined herbal solution and standard drug gave higher zone diameter of inhibition: Klebsiella pneumoniae (25±0.6 mm), Pseudomonas aeruginosa (24±0.6 mm), Staphylococcus aureus (23.7±0.3 mm), Escherichia coli (23.3±0.3 mm) and Candida albican (15±0.6mm), except Proteus mirabilis. The Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal/Fungicidal Concentration (MBC/MFC) of the herbal remedy for all the test isolates (except Candida albican) was 100mg/mL and 200mg/mL, respectively. The result of the phytochemical screening showed the presence of alkaloids, anthraquinones, cardiac glycosides, flavonoids, saponins and tannins, while steroids and resins were absent. Conclusion: The outcome of this study further strengthens the claim of efficacy made by the manufacturer and vendors of the herbal remedy. However, more attention should be given to quality preparations, packaging and storage in view of the general safety of the consumers.

Legal education has changed very little over the last century. At the same time, there have been significant advances in the field of education leading to several theories. The following will examine the five leading theories of education: connectivism, humanism, constructivism, cognitivism, and behaviorism. Each of these will be evaluated next to the Socratic Method, which is the primary method employed by law school instructors. Specific examples of how some of these theories have surfaced in law school and how the Socratic Method embodies other theories will be noted. The effect of technology on law school instruction will also be addressed. The overall goal of this article is to reveal how these theories can be utilized in the law school setting to produce highly competent graduates who will improve the efficacy of the field as a whole. Anecdotal example from North American and African law schools will underscore the notions put forth in this article.

Intimate Partner Violence (IPV) has been identified as a global public health problem of human rights concern. It is a global issue with far reaching consequences for the physical, reproductive, and mental health of women, regardless of social, economic, religious or cultural group. Most of the times, IPV is usually perpetrated by a husband or an intimate male partner of a woman or girl and this is often due to the emotional attachment with or economic dependency of the women on the perpetrators of violence. The outbreak of the COVID-19 pandemic and the lockdown measure, although effective in reducing the disease spread has led to unintended negative consequences. The social, economic and financial distress experienced during the COVID-19 lockdown period has increased the prevalence of Intimate Partner Violence. The financial difficulty associated with the lock-down period has been known to precipitate stress and frustration, and subsequent negative coping mechanisms such as substance abuse and depression; all of which are baseline triggers for intimate partner violence. This has been labelled the silent pandemic. This article examines the rise in incidences of Intimate Partner violence in Nigeria during the COVID-19 Pandemic and contends that Individual Risk Factors, Financial Dependence on the Abuser, Poor Implementation of the rights of women, Cultural Perception of Women, Poor Governance and Resource Management, Lack of Adequate Social Welfare Palliative Schemes, in addition to the complications arising from dealing with COVID-19 pandemic are major factors that have resulted in the surge of Intimate Partner Violence in Nigeria. This work underscores recommendations to curb Intimate Partner violence in Nigeria during and beyond the COVID-19 pandemic, and ensure better realization of the rights and welfare of women and girls such as Legal Framework Reform, Socio Economic Empowerment of Women and girls, Community Mobilization and Behaviour Change Communication, Awareness Creation, and establishment of Sexual Assault Referral and Counselling Centres.

To integrate with the jawbone and gum tissues, a prosthetic dental material must be appealing, long-lasting, repairable, cleanable, and bio-compatible. In terms of new prosthetic materials, prosthodontics is rapidly evolving. Despite the fact that all artificial materials emit compounds into the oral environment, side effects and unpleasant responses are possible. We utilized Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) to conduct an automated and manual search to find clinical studies that looked at the relationship between prosthetic materials and biohazards. A 'ideal' material will have properties that are equal to or very close to those of the material being replaced. One of the most important properties for any material used in the human body is biocompatibility, or more specifically bioactivity. Unlike other implanted materials, the biocompatibility of dental materials varies depending on their structure and state.

Covid-19 pandemic has resulted in death of millions of people across the world. The impact of the disease on human health and the economic hardship on the affected countries have been severe. The public must routinely practice precautionary measures to control the spread of the disease, as no antiviral treatments are currently available. However, the level of awareness and practice of these preventive measures against Covid-19 infection among pregnant women, which constitute vulnerable groups have not been evaluated in our environment. The aim of the study was to determine the awareness and knowledge of pregnant women on Covid-19, its preventive measures and the practice of those preventive measures. It was a cross-sectional study among pregnant women attending antenatal care clinic at Usmanu Danfodiyo University Teaching Hospital, Sokoto. An interviewer administered questionnaire was used to obtain relevant information on sociodemographic characteristics and also their knowledge and practice of Covid-19 preventive measures. All the respondents were aware of Covid-19 infection and the source of information was from Television. All the respondents were aware of the various preventive measures of Covid-19 and the knowledge was good among 98.7% of the respondents. However, only 19.1% had good practice of the preventive measures. Educational status of the respondents was found to have significant association with knowledge of preventive measures (χ2= 9.5, p = 0.014).

This paper reports antibacterial and antifungal activities of Schiff base and that’s of its metal (II) complexes (Co, Cu) derived from salicyldehyde and diphenylamine. The Schiff base and its metal (II) complexes were characterized using different analytical techniques like FTIR, melting point, solubility, and molar conductance, The Schiff base and its respective metals complexes were colored. The result from IR analysis revealed bands at 1614cm-1 indicating the formation of azomethine (C=N) confirming the formation of Schiff base. The band at 664cm-1indicate the formation of complex which is assign toV(M-N) supporting coordination of Schiff base to respective metals. The solubility test result showed that both the Schiff base and complexes are soluble in most organic solvent and insoluble in water. Both the schiff base and complexes revealed sharp melting point and decomposition temperature. The molar conductance data of the complexes in Dimethylsulphoxide(DMSO) show low value of 9 and 10 Ohm-1cm2 mol-1) indicating the complexes are non-electrolytes. The entire compound was tested for their antibacterial and antifungal activities. The results indicated that the growth of the tested organism was inhibited by the compounds.

The classical theory is that before being biologically active, proteins are assembled into a unique three-dimensional structure in terms of quality. These Intrinsically Disordered Proteins (IDPs) are very common in many genomes, including humans and play a key role in central cell processes such as transcription and translation, cell cycle, and cell signaling regulation. In addition, the proportion of proteins associated with various diseases such as cancer and neurodegenerative diseases is very high in IDPs. Therefore, considerable efforts have been made to elucidate the molecular mechanisms supporting the role of IDPs in Biology and disease through the use of experimental and computational methods. Animal models are needed for human genetic anatomy and better treatment options. Genetic disease Although some animals are used key models in academic and industrial research .There is a lot of stress in the anatomy of genetic diseases. The Genetic resemblance of rats and the humans from which is naturally occurring genetic disease, unique population. The availability of structure and complete genomic sequencing has made purebred dogs a powerful model. Used for disease research. The main advantage of dogs is that they suffer from about 450 genetic diseases, of which about half show significant medical symptoms, Similar to the same human disease. Therefore, these two facts make dogs an ideal medical practice, and a genetic model. This review sheds light on some of them, common genetic disease, in dog model. In this article plays an important role in identifying the genes responsible for the disease and / or the use of new genes, treatment of interest for dogs and humans.

In Kenya, the handshake between President Uhuru Kenyatta and Orange Democratic Movement (henceforth referred to as ODM) leader, Raila Odinga, on 9th March, 2018 elicited diverse discourse on the phenomenon. The print media was replete with the discourse on the Uhuru-Raila handshake. This particular handshake ostensibly surpassed the traditional social purview of handshakes as polite greetings. Its conceptualization by Kenyans definitely eluded the precinct of handshakes as greeting occurrences hence the extensive discourse on it. The purpose of the paper was to evaluate the effect of the handshake on the perception of Kenyans by undertaking an analysis of the handshake discourse in Kenya’s print media. The study was guided by Systemic Functional Grammar theory by Halliday (1975). The study adopted analytical research design and data was qualitatively analysed as per the tenets of the aforementioned theory. The study concluded that the Uhuru-Raila handshake had significant influence on the perception of Kenyans on socio-economic and political issues in the country.

Short clinical crowns are more prone to crown dislodgment. Therefore, extra retentive features may be warranted. Though, classic retentive techniques are not always possible to apply in fixed prosthodontics. Hence, it may be beneficial to utilize non-conventional methods to enhance retention in situations where retention cannot be obtained from primary and secondary retentive factors. This article describes a modified technique to increase cast metal and porcelain fused to metal crowns’ retention to cast post and core by using a horizontal retentive pin and hole to lock the crown to the cast post and core.

This paper examines the dynamics surrounding enrolment interventions that have been put in place by key stakeholders in promotion of the 100% enrolment rates in primary schools. The study was guided by the following objective: to determine enrolment dynamics of primary schools in Eldoret West Sub County, Kenya. The study was based on the social demand approach, a model which when applied to education, refers to the aggregate/total demand for school places in a nation (Zimmer, 1985). The researcher adopted a survey research design which aimed at obtaining complete and accurate findings. The design was appropriate for the study since the researcher intended to critically examine enrolment dynamics in Eldoret West, Kenya. From the 177 primary schools in the sub county, a total of 53 schools were sampled. All the 53 Headteachers and all the 5 Quality Assurance Officers in the Education sub county office participated in the study. Data was collected by use of questionnaires, interviews and documents analysis. It was established that there was a significant growth in enrolment due to current government policies. The stakeholders should be mobilized to provide resources needed to expand primary school facilities to ensure equal access to education opportunities for all.

Ever since Ken Saro-Wiwa published his novel Sozaboy in 1985, it has attracted and received tremendous critical attention. However, literary scholars and critics mostly explore either the author’s use of language or his representation of the Nigerian Civil War in Sozaboy. Deploying theories of ecocriticism and regionalism, this paper shifts that focus by examining certain ways Saro-Wiwa articulates his sense of place in Sozaboy and the place, as is well-known, is Dukana – his narrative locus. At the centre of this paper is the contention that Dukana, Saro-Wiwa’s fictional world, is replete with certain characteristics which shape a writer’s vision of place and these include the landscape, culture, beliefs, habits and mannerisms or ethos of a place. Accordingly, I shall analyse Saro-Wiwa’s sense of place in Sozaboy in terms of his perceptions of these characteristics of Dukana. In this way, I propose to locate Saro-Wiwa in the regionalist or place-sense writer’s tradition. I shall further argue that Saro-Wiwa derives his sense of place from what he has seen and known about the Niger Delta region and its people in lived experience. The paper finds that in addition to Saro-Wiwa’s experimentation with language and his concern with the civil war, what also informs his writing of Sozaboy is his desire to articulate rural sensibilities. Drawing from his preoccupation with regional life and events that live on in the pages of his fictional works, the paper concludes that Saro-Wiwa is, for the most part, a regionalist or place-sense writer.

Background/Aim: To date, there is no standard method to evaluate the fit of the implant framework. However, there are many proposed clinical and laboratory methods in the literature with varying accuracies based on numerous factors involved. Therefore, we conducted the current investigation to review the available evidence in the literature, comparing the available clinical as well as laboratory methods in assessing the fit of implant prostheses. Materials and Methods: We searched MEDLINE, PubMed, and Google Scholar databases for relevant studies related to the fit of the implant framework or the degree and effect of misfit. We also used the manual search method to search for any missing articles. Various combinations of key words were used to fit the searching guidelines of each database. Relevant studies of in-vitro and clinical design were included in this review. Results: The majority of the reviewed studies were either clinical or technique papers that proposed various strategies in detecting the fit of the implant framework, with a very limited number of clinical trials related to the topic. Multiple factors suggest that the concept ‘passive fit’ could be achieved in implant prosthodontics with the use of advances strategies. Various clinical and laboratory techniques in assessing the fit of the implant framework were identified. The advantages, drawbacks, and applicability of each technique are discussed. However, the applicability of these technique is clearly limited due to the absence of clinical trials (in vivo studies) assessing their validity and efficacy of such techniques. A slight misfit of the framework to the implant abutment/analogue was also observed in many of the investigated strategies. Conclusions: Due to the variations of techniques and the various parameters assessed by each, we suggest that it might be useful to combine several techniques to determine the accuracy of fit, quantify the effect and degree of misfit, and subsequently estimate the acceptable level of fit, using the reference system for each technique used accordingly.

Intimate Partner Violence (IPV) has been identified as a global public health problem of human rights concern. It is a global issue with far reaching consequences for the physical, reproductive, and mental health of women, regardless of social, economic, religious or cultural group. Most of the times, IPV is usually perpetrated by a husband or an intimate male partner of a woman or girl and this is often due to the emotional attachment with or economic dependency of the women on the perpetrators of violence. The outbreak of the COVID-19 pandemic and the lockdown measure, although effective in reducing the disease spread has led to unintended negative consequences. The social, economic and financial distress experienced during the COVID-19 lockdown period has increased the prevalence of Intimate Partner Violence. The financial difficulty associated with the lock-down period has been known to precipitate stress and frustration, and subsequent negative coping mechanisms such as substance abuse and depression; all of which are baseline triggers for intimate partner violence. This has been labelled the silent pandemic. This article examines the rise in incidences of Intimate Partner violence in Nigeria during the COVID-19 Pandemic and contends that Individual Risk Factors, Financial Dependence on the Abuser, Poor Implementation of the rights of women, Cultural Perception of Women, Poor Governance and Resource Management, Lack of Adequate Social Welfare Palliative Schemes, in addition to the complications arising from dealing with COVID-19 pandemic are major factors that have resulted in the surge of Intimate Partner Violence in Nigeria. This work underscores recommendations to curb Intimate Partner violence in Nigeria during and beyond the COVID-19 pandemic, and ensure better realization of the rights and welfare of women and girls such as Legal Framework Reform, Socio Economic Empowerment of Women and girls, Community Mobilization and Behaviour Change Communication, Awareness Creation, and establishment of Sexual Assault Referral and Counselling Centres.

From the angle of Sustainable Development Goals (SDGs), this research note explores renewable energy in food supply chain and sustainable marine fishery. With an initial theoretical analysis, it is observed that the share of renewable energy, as reflected by SDG Indicator 7.2.1, can contribute to the measurement of and data computation for SDG Indicators 12.3.1 and 14.7.1. This is because renewable energy becomes a significant component of on board cost for harvesting, processing, and preserving fishes by marine vessels/fleets. Also renewable energy can be used to estimate food waste because it functions as an estimation for municipal solid waste if data is not directly available. A number of scientific and practical implications are generated. For example, more interdisciplinary studies on the interactions across SDGs should be encouraged, and more in-depth empirical research are also expected in future. The connections between renewable energy, food supply chain, and sustainable marine fishery also call for more holistic policies for sustainable development, with adequate consideration of disparities in country contexts. Effective actions should be taken to further enhance the statistical capacities of countries and international organizations, which will be a foundation for applying more sophisticated techniques into the analysis of data in this field. The main objectives of this short research note are to provoke more scientific thoughts and provide policy-oriented recommendations. It leaves spaces for more empirical evidence-based future research including another study under the author’s plan.

Background: The aim of the study was to describe epidemiological aspects and clinical characteristics of these patients, as well as diagnostic work-up, comprehensive management and updated follow-up. Methods: In a 4-years’ period, 6 female and 4 male fetuses were diagnosed with NTD in Department of OBG at Victoria Hospital, BMCRI, Bangalore. Analyzed data were related to familiar and/or maternal risk factors (consanguinity, maternal preexisting and/or gestational diseases, exposure to teratogen/infectious agents, lack of preconception folic acid supplement), demographic (ethnicity/origin, residence) and clinical features (eventual use of assisted reproduction techniques, prenatal diagnosis, gestational age, fetal presentation, type of delivery, birth weight, preoperative imaging, antibiotics and analgesics use, description of the surgery intervention, length of hospital stay, comorbidities, complications), and follow-up. Results: Among 10 cases, 6 female and 4 male fetuses were diagnosed with NTD. All 10 fetuses had Anencephaly and other associated anomalies. The diagnosis was made by prenatal ultrasonography. Among ten mothers one was over-aged. Medical history revealed that only 2 mothers used folic acid (FA), -tablets containing 5 mg folic acid, once daily, beginning after being aware of the pregnancy- neither initiated preconceptionally, nor consumed regularly. The remaining 8 mothers did not use any supplements. No mothers used any kind of drugs during pregnancy, and 2 were diabetic. All patients had normal thyroid, liver and renal function tests. Abdominal ultrasonography revealed no abnormality.