This study was descriptive cross-sectional study, aimed to study the effect of nutritional status, and lifestyle habit among type 2 DM patients in Surman, Western-Libya. A total of 130 type 2 DM patients were enrolled in this study, which was carried out in the period from March to (July 2017). The results were showed that, from 130 type 2 DM patients were recruited for this study, 53 (40.8%) were males, while 77 (59.2%) were females. Out of 130 participants, 47 was normal BMI (36.2%), while 81 was overweight (62.3%) and only 2 was underweight (1.5%). This study was revealed that from 130 participants of type 2 DM patients 88 have taken an ideal diet (67.6%), while 42 were not (32.4%). Moreover, only 37 patients were done physical activities (28.5%), while 93 patients were not (71.5%). Also, the study was shown that 81 patients were exposed to mental stress (62.3%), whereas 49 their life was normal (37.7%). The conclusion, the nutritional status, and lifestyle habit have a great advised effect among type 2 DM patients in Western Libya. It can be concluded that the majorities of individuals with type 2 diabetes were overweight, due to lack of physical activity, and did not follow dietary guidelines for fats, fruits and vegetable consumption. Additional measures are needed to encourage regular physical activity and improve dietary habits in this population.

The need to communicate with the other members of the society for different purposes leaded to the need to learn a foreign language, a second language. Thus the people who spoke two or more languages have more access on communication. The easy way to communicate that was as the result of knowing a foreign language, had a lot of advantages in every field of life. Nowadays speaking and writing another language is more than a necessity. The following paper treat the effectiveness of bilingual education as a theoretical concept, how help the young learners and the benefit in the Albanian education system. The Albanian education system now days have changed and these are reflected even in accepting and entering a foreign language to the school system. Classes have pupils/ learners of different background and teachers use several methods and programs. According to the level of the classes there are used different programs.

Abstract: We describe the first and rare case report of a cryptogenic organizing pneumonia (COP) in a seventh decade diabetic and hypertensive women from low highlands, Jazan, Saudi Arabia. The evidence of the clinical scenario, laboratories testing , radiological images findings followed by treatment with steroid is quite enough to diagnose COP, irrespective of lung tissue biopsy procedures and processing accessibility for histopathology, in a timely manner as reveals in Yahya Al-FIFI’s diagnostic criteria for cryptogenic organizing pneumonia (COP) without a lung tissue histopathology. We started a methylprednisolone forty milligram intravenously every eight hourly for seven days which is showing a dramatic clinical improvement within initial twenty-four hours of first seven days and complete recovery clinically and radiologically, at the end of the following fourteen days of tapering prednisolone doses without a relapse for seven months. Our successful experience approach in this case of COP has several advantages include that an early diagnosis and introduction of methylprednisolone may lead to preserve lung function, avoidance of biopsies procedure complications, may prevent relapses, early hospital discharge, improve the morbidity, mortality and the quality of life of the patient. So, we conclude these clinical, laboratories testing, and radiological findings are quite enough to diagnosing and treating with methylprednisolone to rescue patient life, when a lung biopsy performance accessibility or feasibility is obscured or delayed. We observe that beta-lactam; ceftriaxone and piperacillin/tazobactam, glycopeptide; vancomycin and macrolide; clarithromycin antibiotics are not effective in our patient COP case scenario. “Yahya Al-FIFI’s diagnostic criteria for cryptogenic organizing pneumonia (COP) without a lung tissue histopathology is easy and sufficient enough to assess physician to diagnose COP in acceptable time frame and may have favorable outcome over all.

In this paper, I argue that there is clear evidence of neglect of higher education in post-independent South Sudan. The study, therefore, interrogates the scope of the higher education crisis in the country and assesses prospects for change from the standpoint of equity and quality using institutionalism as a theoretical framework. The study points out that the crisis of the system runs through the tapestry of South Sudan’s history of state formation against which the variable of nation-building at the dawn of Independence in 2011 has failed to assign adequate value for higher education in the pursuit of the objectives of national transformation in particular, and modernisation in general. It remains to be seen if the political leadership and the academic community could define the payload of South Sudan’s higher education system as the country transitions into a constitutional democracy capable of according greater autonomy and initiative to its universities; and revisiting the whole gamut of post-secondary education in order to render it more responsive to addressing the needs of society, particularly in non-academic streams of learning. Besides the historical and institutional challenges, the higher education system of South Sudan must expedite its internationalisation as its formative years wane out. The fundamental requirement is for its competent and dynamic scholars to lead a spirited dialogue and concerted action that should not be broken off by recurrent political violence. This is a must if South Sudan is to stand on the cusp of real transformation in its higher education landscape.

Abstract: Choosing a career path for graduate students could be a big challenging decision. It is often influenced by many other intervening factors such as, personality, type the available specialty path, social and the list goes on. It is natural for many freshly graduate medical students prefer to work in a medical facility with high technical setting to gain the needed experience. This preference seems to transcend cultural differences; it is noticed in different societies around the globe. Community based education (CBE) could offer a more community oriented path for educating students, motivate them, make them passionate about practicing in rural settings. This review highlights the results of studies done regarding Community based education (CBE) by different researchers with different ethnic and cultural backgrounds. Extensive internet search has been done on research and experiments regarding Career Preference and community based education. A positive association between the CBE and the choice of students to work in rural areas has been reported. The feedback from students engaged in this program was quite satisfying.

Abstract: Medical professionals around the world are facing new challenges day in and day out. With the ever-growing advances, the ever-expanding populations and ever complicating life issues, doctors are expected to in their best order and shape at every snap shut of time. This review highlights the principles of medical professionalism. Literature search strategy included electronic database searches, internet searches, hand searching, ancestry searching and networking. The new aspects of medical professionalism are providing a framework within which doctor duties towards the patients are being met with the enhancement with doctor qualities. So much accentuation nowadays is made on patient’s autonomy and confidentiality. In this review, these aspects of the professionalism are being discussed.

In pharmaceutical industry, researchers aim at catering to the need of robust analytical methods for analysis of generic drug products. A simple, novel and efficient stability indicating HPLC method has been developed in a multi component drug formulation for simultaneous estimation of Salbutamol, Theophylline and Ambroxol in presence of their degraded products. This HPLC method uses Inertsil ODS C18 column HPLC column, phosphate buffer pH 6.3 and Methanol: Water: Acetate Buffer 60:35:05 v/v as mobile phase in isocratic mode with UV detection at 239 nm. The method was validated and found to be precise, robust, accurate, linear (range of 1‐6μg/ ml, 50-300 μg/ ml and 15‐90 μg/ ml for Salbutamol, Theophylline and Ambroxol respectively), and specific for degraded products ensuring suitability of the method for quantitative determination of Salbutamol, Theophylline and Ambroxol. The method is stability-indicating, and therefore qualified and reliable for demonstrating and detecting any expected change or degradation in the drug product during stability studies. The method developed here is found to be novel, robust and rugged enough to reproduce accurate and precise results under different method conditions

The present study was aimed to look for the effect of a natural compound i.e. Crocin on the viability of mature adipocytes and on inhibition of adipocyte differentiation. The 3T3-L1 cell line is one of the most well-characterized and reliable models for studying the conversion of pre-adipocytes into adipocytes. 3T3- L1 pre-adipocytic cell line was used and differentiated into mature adipocytes using standard adipogenic media. The MTT assay was used for the assessment of cell viability whereas effect on adipocyte differentiation was visualised by Oil Red O staining. The changes in relative lipid content were monitored spectrophotometrically at 510nm. Mature adipocytes when treated with Crocin decreased cell viability in a dose dependent manner. It also showed an enhanced inhibition of adipocyte differentiation as monitored by Oil Red O Staining. The western blot analysis revealed significant increase in the expression levels of AMP activated protein Kinase which is a key regulator of energy homeostasis. Thus, the crocin seems to affect multi-potent anti-obesity parameters and may have promising benefits for the treatment and prevention of obesity.

One of the common clinical observations regarding long-standing diabetes is peripheral neuropathic pain, probably due to its destructive effects on the pain modulating neurons of the dorsal gray column of the spinal cord. Accordingly, the current study was aimed to analyze the effect of experimental hyperglycemia on pain modulating neurons in the lamina I-III of lumbar region of spinal cord of albino rats. Thirty-six albino rats with average weight ~250 g were grouped equally into six. Diabetes was induced with a single dose of streptozotocin (STZ, 60 mg/kg, i.p.). At the end of each experimental period, rats were euthanized by deep ether anesthesia, blood was collected and animals were perfused with Karnovsky fixative. Spinal cord was dissected and processed for histopathological and morphometric parameters and blood for biochemical analysis. Biochemical analysis of all diabetic groups revealed increased serum creatinine and reduced serum total protein. Histopathology and histomorphometry of dorsal gray column and ependymal cells and surrounding structures revealed that with the progressively increasing duration of hyperglycemia was associated with decreased number of pain modulating neurons in the lamina I-III as well as ependymal cell and in addition deposition of collagen fibers in the tunica adventitia of spinal arteries and around the small spinal vessels. The associations of long-standing hyperglycemia with reduction of dorsal gray column inter neurons, demyelination of nerve fibres and excessive deposition of collagen fibers in the tunica adventitia of blood vessels appear to be important contributing factors likely to be responsible for the diabetes-induced peripheral neuropathic pain

Abstract: Since the dawn of the era of innovation, the need for novel methods in making life easier has been interminable. The learning process shows no exceptions to this rule. One would argue for the classic methods in handling the trade of information between the teacher and the students, which has been unilateral. The introduction of problem based learning (PBL) process to the system of education is facing many struggles. In this student-centered active learning process, the teacher is just a guide focal point of education systems. Literature search strategy included electronic database searches, internet searches, hand searching, ancestry searching and networking. Objectives: The objective of this review article is to study the challenges, obstacles and critical incident in PBL tutorial groups. Problem base learning model is counteracting by a lot of educational, financial and psychological challenges and barriers.

Ultrasonography is the most common screening test for cholecystitis and cholelithiasis. It is easy, non invasive, and safe and a highly accurate imaging technique that can also detect associated lesions of the liver, pancreas and common bile duct (CBD). Recent studies have demonstrated that laparoscopic removal of gallbladder may be accomplished with a morbidity and mortality rate comparable to or less than that of traditional open cholecystectomy. The present study was conducted to look for some predictive factors on ultrasonography of gallbladder that can give surgeon some idea about the potential difficulty and complications that may be encountered during the course of laparoscopic cholecystectomy. This study presents analysis of 51 patients of cholelithiasis, requiring elective cholecystectomy from 1st May 2008 to 30th April 2009. The study was conducted in the Department of Surgery and Department of Radio diagnosis, G.R. Medical College, Gwalior (M.P.). The ultrasonography of the patients was done on the day of surgery in the department of Radio diagnosis, G.R. Medical College, Gwalior. The patients were fasting overnight for the maximal distention of the gallbladder. The ultrasonography was done with 3.5 Mhz probe on Diatonic spectra color Doppler ultrasound on B mode, gray scale, real time scan.The mean gallbladder wall thickness in the study was 2.9 mm (maximum - 5.6 mm and minimum – 1.8 mm). There were 8 patients who had gallbladder wall thickness more than 4 mm. There were 7 (13.2%) patients with contracted gallbladder. There were 6 (11.76 %) patients with gallstone impacted at the neck of gallbladder or Hartman's pouch. There were only 2 patients with common bile duct diameter more than 6 mm. Out of total 51 cases 7 (13.72%) cases were converted to open procedure. Significant correlation was found between the independent ultra-sonographic parameters (that is gallbladder wall thickness, contracted gallbladder, stone impaction at the neck of gallbladder) with the difficult laparoscopic cholecystectomy and their subsequent conversion to open cholecystectomy. The most valuable assessment the ultrasound can provide is the gall bladder wall thickness, gall bladder size, CBD diameter and CBD stones and any abnormal anatomy of the biliary tract if present. Thick gallbladder wall is a finding, which may show that more adhesions may be found during surgery.

Marine macroalgae produce a great variety of biological active compounds which cannot be scientifically characterized with in other organism’s biomass. These marine habitats have been scientifically reported for modern medicinal uses although rheteoratically associated to coastal communities’ healthy eating and folk medicine practice. In tandem to this, these marine macroalgae have highly potentiate themselves as a tangible source of functional ingredients that is industrial applicable. Globally various division of geochemical marine macroalgae flora taxa (Chlorophyta, Phaeophyta, and Rhodophyta) flourish. However, despite substantial optimised yield and empirical evidence of their health potential benefits, these macroalgae remained largely pharmaceutical and medical related industries innovative unexploited. Of these leads compounds, sulfated polysaccharides offer a wide range of physiological and chemical-biological activities that include antioxidative, anticoagulant, antiviral, antitumor, anti-inflammatory, antihyperlipidemic and antihepatotoxic activities. Per se, the optimization of sulfated polysaccharides as functional food and Vis a Vis, as therapeutic agents is this millennium important research agenda. As such, this review extrapolates the bioprospect of sulfated polysaccharides (Sulfated galactans, Fucans, and Ulvans) from geochemical signature macroalgae potential context as functional food and as tangible source for drug discovery.

The Swedish financial crisis, dealing with financial deregulation and the boom in the late 1980s, the bust and the financial crisis in the early 1990s, the recovery from the crisis and the bank resolution policy adopted during the crisis are reviewed. The paper focuses on: the causes and consequences of the financial crisis, and the applicability of the Swedish model of bank crisis management for countries currently facing financial problems.

Obesity, a pathologic state characterised by excess fat reserves, is a serious health problem that increases the risk of numerous medical complications and mortality. The disease arises as a direct consequence of alterations in regulating energy balance in the body. The recent global rise in the prevalence of Obesity and unavailability of effective anti-obesity drugs has created an urgent need to understand and identify the important aspects related to the disease. In this review, we provide a perspective on the factors influencing Obesity, Obesity-associated disorders, pharmacological interventions and several other important concepts related to the disease.

Eventhough Tuberculosis is widespread in India; parotid gland involvement is very rare. TB primarily affects the lung, but in about 15 – 20% of the cases extra pulmonary involvement can be seen. Here we present a case of TB parotid abscess in a 45 year old diabetic male patient