ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
Study on Antimicrobial Efficacy of an Indigenously Prepared Herbal Ophthalmic Solution against Selected Eye Pathogens Associated With Eye Diseases
Dr. Ranjan Padhy, Santosh Kumar Dash
Page no 74-80 |
10.21276/haya.2018.3.1.14
Aqueous plant extracts in ophthalmic preparations is not uncommon.
Folklore (Indigenous) herbal preparations in this regard claim to cure eye diseases
need to be explored. Antimicrobial potency of such herbal formulation is studied with
comparison of its efficacy against selected pathogens associated with eye diseases
helps for its standardization and validation as well. Hence Herbal formulations were
taken and their antimicrobial efficacy was compared with standard treatises against
wide range of eye pathogens. Both agar well and disc diffusion methods were
followed for this purpose. Effect of extract on viability of microbes was also studied
taking absorbance data at 600nm spectral wavelength. The multidrug resistance of the
strains was also tested prior to their use in antimicrobial sensitivity test. The
antibacterial efficacy of standard eye drop showed highest zone of inhibition against
E. coli and lowest against P. vulgaris. Similarly the indigenously prepared eye drop
was found to be with fewer efficacies. However the 50% diluted ophthalmic
preparation showed higher degree of inhibition was revealed. The study explored that
the diluted and standardized indigenously prepared ophthalmic solution can be used
as a more potential drug at least against microbe associated and induced eye diseases.
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
Assessing Food Quality Delivery in the School Feeding Programme and Its Impacts on Enrolment: A Study of Some Public Basic Schools in Bawku Municipality of Ghana
Grace Efua Owusu Gyasi, Mrs. Maureen Nkansah Asante, John Adanse, Sussana Antwi-Boasiako
Page no 98-106 |
10.21276/sjbms.2018.3.1.13
School feeding has been an effective safety net that has prevented countries
affected by economic challenges from adopting negative coping strategies. The study
assessed the food quality of the Ghanaian School Feeding Programme in Bawku
Municipality, in the Upper East Region. Some of the specific objectives were; to
assess the wholesomeness of the foodstuffs used in the preparation of meals for the
school pupils and also examining the impacts of the school feeding programme on the
basic education in the Bawku Municipality. The study highlighted some of the
challenges confronting caterers who are involved in the school feeding programme. A
survey research design was employed to obtain the data from primary and secondary
sources. The primary data was obtained through a structured questionnaire
administered to 120 respondents in 10 randomly selected public primary six pupils and
two caterers each from the selected schools in Bawku Municipality. The retrieved data
was analysed using Statistical Package for Social Sciences (SPSS) version 20.0 and
the results were presented in the form of tables and figures. The results showed that
(70%) of the basic schools under the school feeding programme in Bawku
Municipality enjoy quality food and this has led to an increased in pupils’ enrolment,
and class attendance. The major challenges were found to be the delay in releasing of
funds to caterers. It was recommended that, the government of Ghana should provide
the Municipal Assembly with resources to help monitor and evaluate the
implementation of the program for improvement. Moreover, the municipal assembly
should find a better storage facility for the schools under the GSFP to help keep the
food safe for a longer period without introducing chemicals that has a longer effect on
the food and harmful to pupils.
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
Evaluation of Antiinflammatory Activity of Whole Plant of Caralluma umbellata Haw. (Apocynaceae) In Albino Rats
Rajan Michael Evanjaline, Veerabahu Ramasamy Mohan
Page no 32-35 |
10.21276/haya.2018.3.1.7
Vascular tissues respond as an inflammation to adverse stimuli like
pathogens, bruised cells or an irritant. An inflammation manifests itself as redness,
swollen joints, pain at joints, stiff joints and impaired joints. Currently inflammation
is treated by NSAIDS. However, drugs used to treat inflammation can potentially
lead to enhanced risks of blood clotting which in turn can end up fatal heart attacks or
strokes. This scenario has hence necessitated a search for alternate drugs derived
from medicinal plants. Their chemical diversity also make them rich and possible
sources of drugs without accompanying adverse side effect. Therefore a study in this
direction will be both rewarding and unfulfilling. The objective of this study was to
evaluate the antiinflammatory activity from the ethanol extract of whole plant of
Caralluma umbellata in carrageenan induced paw edema in Wistar Albino rats. This
study was compared to a positive control drug, indomethacin. The ethanol extract was
given in a concentration of 200 and 400 mg/kg body weight. Ethanol extract of C.
umbellata whole plant with a concentration of 400 mg/kg b.w. showed maximum
(85.44%) inhibition on carrageenan induced rat paw edema at 3rd hour. The effect was
significantly (p<0.001) higher than that of the standard drug indomethacin (84. 78%).
From the result, it can be concluded that the antiinflammatory activity of C.umbellata
ethanol extract of whole plant may be due to the presence of secondary metabolites in
the extract.
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
Loneliness at Work: Gender and Hierarchical Level Differences of Employees at Thai Government Bank
Dr. Chaiyaset Promsri
Page no 1-6 |
10.21276/sjbms.2018.3.1.1
This study aimed to explore the gender and hierarchical level differences
in loneliness at work. A sample of 143 employees who worked at the Thai
government bank headquarters was gathered by using proportional stratified
sampling technique. Loneliness at Work Scale (LWS) was modified to use as the
instrument for data collection. Results of independent samples t-test analysis
revealed that there was a significant difference in males and females with respect to
loneliness at work (t = 3.079, p < 0.002). This suggested that males were
experiencing loneliness at work more than females. Results also showed a
significant difference in employees and employers with respect to loneliness at work
(t = -3.458, p < 0.001). This suggested that employees were experiencing loneliness
at work less than employers. This present study suggested that the further study
should compare mean differences of loneliness in the workplace in other sociodemographic variables.
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
Impact of Physical Activity Profile and Tobacco Consumption on Cardiometabolic Diseases of Cameroonians in Dschang Health District
MBS Dandji, FN Zambou, FCN Nana, EPS Fodja, D Lemogoum, DSB Dangang, FM Tchouanguep
Page no 36-45 |
10.21276/haya.2018.3.1.8
This study aimed at studying the epidemiology and prevalence of risk
factors for cardiometabolic diseases. 254 male subjects aged between 30 and 60 years
old and apparently in good health having consented freely. They were randomly
selected from 10 health areas, including 5 in urban area (n=107) and 5 in rural area
(n=147), in Dschang Health District. After obtaining the ethical clearance, the level
of physical activity, the data on socio-demographic conditions and smoking were
identified by a simplified questionnaire. With the help of nurses and investigators,
anthropometric measurements, blood pressure, umbilical perimeter, waist
circumference, body mass index and fasting blood glucose were measured.
Approximately 5 ml of blood was taken at the elbow for biochemical assays. The
collected data were submitted to the EPI-InfoTM version 7.1.5.0. Software. Results
showed that 83% of people were inactive in rural area and the 41-50 age group was
more inactive (18.03%) whereas in the urban area there was 76.19% of inactive
people and the 51-60 age group recorded the most inactive individuals (43.83%)
(P>0.05). The inactive population showed 38.24% overweight and 14.7% obese.
Smokers represented only 20.55% in rural area and 16.82% in urban area.
Triglycerides, which were higher among smokers in rural area (349 ±49.23 mg/dl at
P>0.05) than in the urban area for former smokers (343.78 ±48.08 mg/dl) who had a
higher rate but without significant difference with the other categories of smokers
(P>0.05). Atherosclerosis index of smokers from urban area was higher without
significant difference compared to other groups.
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
Synthesis, Spectral Characterization and In-Vitro Screening of Some Novel Tetrahydroquinoline Derivatives for Their Antitubercular, Antioxidant Activities
Pradeep Kumar, Rajesh D. Hunashal
Page no 151-155 |
10.36348/sjmps.2018.v04i01.022
In an attempt to synthesize some novel, potent antitubercular and antioxidant agents here we have reported the synthesis of a novel series of tetrahydroquinoline derivatives (III a-g). In this the titled compounds were synthesized by the reaction between substituted aromatic primary amines, N-vinylpyrrolidin-2-one and 4-nitro phthalic acid in acetonitrile. Structure of the synthesized compounds were confirmed on the basis of their physico-chemical and spectral data (IR, 1H NMR, 13C NMR and Mass). All the synthesized compounds were screened for their antitubercular and antioxidant activities using the Microplate Alamar Blue Assay (MABA) method and nitric oxide scavenging, DPPH method respectively. For antitubercular and antioxidant activities screening isoniazid and ascorbic acid were used as the standard drugs respectively. Among the synthesized compounds III a, III d and III e have shown significant anti-tubercular activity and compounds III a, III b and III e have shown significant antioxidant activity
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
Comparison of the Effects of Laser Pasteurization and Heat Pasteurization on The Cow’s Milk
Amna O.B Malik, ALI A. S. Marouf
Page no 46-50 |
10.21276/haya.2018.3.1.9
The main objective of this work was to investigate the cow’s milk
ingredients percentage after pasteurized using laser and heat treatment in order to
compared them with untreated milk. In this work, fresh cow’s milk sample (360 ml)
were obtained from farms of Sudan University of Science and Technology, the
sample was divided into three parts, the first part pasteurized by Nd: YAG laser with
output power of 50 watts for two minutes, the second part pasteurized by heating to a
temperature of 72°C for 15 seconds the third part was control sample used as
obtained. Moisture content, crude protein content, crude fat, ash content, total solid
(TS) content, lactose content, pH of the milk samples and titratable acidity were
analyzed for the three samples. The obtained results revealed that the ingredients
percentage reduced in all heat-based pasteurized milk components compared to laserbased pasteurized milk components.
RESEARCH ARTICLE | Jan. 30, 2018
Evaluation of Milk Kinship Formation via Early Breast-Feeding
Amad Abdelkarim El Marghani, Idris Adewale Ahmed
Page no 61-69 |
10.36348/sjmps.2018.v04i01.009
Consanguinity constitutes one of the major health problems worldwide, in which consanguineous marriages are associated with an increased risk for congenital malformations and autosomal recessive diseases. Although the advancement in modern biomedicine and forensic laboratories techniques continue to guide scientists to move forward to unravel many life sciences secrets, it is still ambiguous to investigate the full picture of milk kinship and its related consanguinity. Theoretically, it is possible to see such consanguinity developed from early sufficient breast-milk feeding. Thus, scientists should cooperate to investigate the problem practically to find a proper solution. This review article focuses on the alleged consanguinity that evolves from milk breastfeeding or beyond through wet nursing or milk formula feeding. Additionally, this article proposes the idea of removing milk genetic components to establish a new safe genetically free formula as a promising solution
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
Effects of Alkali Concentration and Temperature on the Imbibition Properties of Okro Stem Habiscus esculentun Fibre
Abubakar Ahmed Hamidu, Mayen Nelson Ekott
Page no 51-55 |
10.21276/haya.2018.3.1.10
Okro fiber was obtained from okro stem by soaking in ammonium oxalate
for 20minutes.The effect of alkali treatment (mercerization) on 10grammes of each
sample was investigated. Various concentration of the NaOH (Sodium hydroxide)
ranging from 0% to 22% was prepared. The temperature of the treatment was varied
from 25 to 40oC .Water imbibitions studies was also carried out on the fiber samples
by varying the temperature and concentration of the fiber samples obtained. Result of
treatment of the fiber with ammonium oxalate indicated a whitish lustrous material.
The mercerization effects on the fiber indicated an increase in mass of the fiber from
an initial weight of 0.4g in 1.0M to 0.8g in 4.0M at 25oC .On the other hand, there
was a substantial swelling noticed in the case of the fiber sample treated with 1.0M
(0.6g) to 0.9g (4.0) at 40oC.For imbibitions studies, the water uptake recorded the
best value with fiber treated with 1.0M showing a maximum imbibitions value at
25oC. The overall results of the study indicated that treatment of fiber with chemical
enhanced some crucial properties of the fiber and has inhibited substantially the
amount of water absorbed by fibrous materials. Industries involved in the exploration
of natural fibers as potential fibers may benefit immensely from this investigation as
this may add to the list of fiber utilized for fiber production due to its abundance.
CASE REPORT | Jan. 30, 2018
Hereditary gingival fibromatosis about a Case
Faiçal Choumi, Mohamed Sina, Mohammed Moumine, Mohamed Nassih
Page no 138-139 |
10.36348/sjmps.2018.v04i01.019
Hereditary gingival fibromatosis (FGH) is a gingival pathology of genetic origin characterized by a slow and progressive proliferation of the keratinized gingiva. The diagnosis is clinical, confirmed by histology. The treatment is surgical and involves the excision of excess tissue with gingivoplasty, but the recurrence rate remains high, especially in severe cases. We report a case of generalized FGH, whose evolution was favorable after surgical treatment. Observation: A 42-year-old patient, with no notable history, who presented in our consultation for a gingival hypertrophy evolving since childhood. Endobuccal examination showed diffuse gingival hypertrophy with poor oral status. Gingival biopsy revealed gingival fibromatosis. Treatment consisted of excision of excess tissue with gingivoplasty. No recidivism after a decline of three years. Discussion: FGH is a genetic gingival pathology whose clinical appearance is variable, it may be generalized or localized to a maxillary sector, isolated or associated. The positive diagnosis is mostly clinical confirmed by histology (hyperplastic epithelium and dense connective tissue), the treatment is surgical and consists of excision of excess gingival tissue with gingivoplasty. Our patient has a severe FGH that has evolved after surgical treatment
REVIEW ARTICLE | Jan. 30, 2018
Ethno-Ecology of Pandanus Fasicularis Lamk, the Bulga Plant of Ganjam Hinterland, South Odisha, India
Dr. Ranjan Padhy, Santosh Kumar Dash
Page no 64-67 |
10.21276/haya.2018.3.1.12
Exploration of vegetations in ecologically significant areas became
underline research in modern approach. In this regard the East Indian coastal belt at
Ganjam district has been chosen as the study area and the ethno ecology of Pandanus
fascicularis Lamk was focused. Normal taxonomic and ecological overviews were
adopted to establish the vegetational data. The various ethno biological, ethno
ecological uses, medico folklore remedies approaches were strictly adopted. The
various data so procured are compiled and greater emphasis of this plant was laid as
comprehended from the utility and general psychology of the people who took this as
a crop more than that of rice was confirmed as each and every part of the plant is used
in one or the other way. On the contrary, the study area (Ganjam Hinterland) is
designated as the sacred groove for this plant owing to the part played by the plant for
the people’s economy and biodiversity conservation as well.
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
The Influence of Service Quality, Brand Image and Promotion on Purchase Decision at MCU Eka Hospital
Hapzi Ali1, Evi Narulita, Adi Nurmahdi
Page no 88-97 |
10.21276/sjbms.2018.3.1.12
This study aims to determine the effect of service quality, brand image and
promotion of purchasing decisions at MCU Eka Hospital. The research design used
was quantitative and descriptive. The study population included 396 service users of
MCU Eka Hospital. The sample size is 76 respondents by using purposive sample
method. The research data was collected by distributing questionnaires to obtain the
required data. Data testing techniques include instrument test and classical assumption
test. Methods of data analysis used are multiple linear regression analysis method, t
test, f test, coefficient of determination test (R2) and inter-dimensional correlation
analysis with the help of SPSS 23.0 for windows program. The results showed that the
quality of service, brand image and promotion have a significant positive effect
simultaneously to the purchase decision at MCU Eka Hospital. Partially the quality of
service has a significant positive effect on purchasing decision, brand image has a
significant positive effect on purchasing decision and promotion have a significant
positive effect on purchasing decision. Further research is suggested to add other
variables that influence purchasing decisions that have not been used in this study such
as price, product and customer relationship management.
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
Bio-Ethanol Derived from Less Edible Fruit Cultivars of Coorg District (Karnataka) and Parametric Analysis Using IC Engine Fuelled with Bio-EthanolDiesel Blends
Thouseef Ahamad MY, Panduranga Murthy G, Rajesh Kumar, Manjunatha R, Leelaja BC
Page no 81-98 |
10.21276/haya.2018.3.1.15
The sustainable production of ethanol from implausible bio-resources like,
less or non-edible fruit samples are focused in the current investigation. Bio-ethanol
is a fuel ethanol (ethyl alcohol), the same type of alcohol found in alcoholic
beverages. It is most often used as a motor fuel, mainly as a bio-fuel additive for
gasoline. Therefore, an attempt has been made to obtain a fuel grade ethanol using
fruit samples like, Passion fruit (Passiflora edulis, L) and Cashew Apple
(Anacardium occidentale, L.) by fermenting them with the help of flocculating yeast
(Saccharomyces cerevisiae, L). The outcome of the experimentation facilitated to
obtain 48% alcohol after finishing point of distillation processes; it can be can
envisioned that, an optimized concentration of ethanol has been obtained on ensuing
to standardization of the protocol. This bio-ethanol has been further subjected for
physico-chemical characterization and found that, it can be one of the most promising
types of bio-fuels that can be explored from the fruit resources. Hence, in the studies,
the technological attributes of flocculated Yeast (Saccharomyces cereviseae) was
employed to rationalize its use in alcoholic fermentation, thereby, the enhancement in
the production of bio-ethanol from the selected fruit cultivars at significant level was
achieved with a speed of about three to four folds greater than the yield reported in
the earlier studies. Further, the ethanol samples were evaluated for Gas
chromatography; the yield of ethanol, sample-4 (Passion fruit juice) gave 100%
purity of ethanol as compared to standard. The bio-ethanol obtained as a result of
fermentation was further subjected for the evaluation of Engine performance using
single cylinder IC Engine with standard specifications.
CASE REPORT | Jan. 30, 2018
Lipoma of the Parotid About Three Cases
Faiçal Choumi, Mohamed Amine Ennouhi, Mohamed Sina, Lahcen Khalfi, Mohammed Moumine, Mohamed Nassih
Page no 57-60 |
10.36348/sjmps.2018.v04i01.008
The parotid gland lipomas are rare; they are located mainly in the superficial lobe. We report 3 cases of parotid lipomas whose diagnosis was suspected by tomodensitometry and confirmed by histology. Treatment was a superficial parotidectomy for two patients and enucleation for one patient. Parotid lipomas are located mainly in the superficial lobe. The diagnosis is based on imaging, but only histology can confirm. The treatment of superficial lipomas is based on superficial lobe parotidectomy but sometimes enucleation could be enough. In all cases, the recurrence rate is very low
ORIGINAL RESEARCH ARTICLE | Jan. 30, 2018
Hepatoprotective Potential of Methanolic Extract of Gymnema sylvestre Leaves on Acetaminophen-Induced Liver Damage in Wistar Strain Albino Rats
Oshobu ML, Alhassan AJ, Mansura A, Ononamadu CJ, Ibrahim A
Page no 1-8 |
10.21276/sjbr.2018.3.1.1
Drug-induced liver injury is a potential complication of all medications
because the liver has a central role in the metabolism of drugs and toxic substances.
This study was designed to evaluate the hepatoprotective activity of the methanolic
extract of Gymnema slyvestre leaves on acetaminophen-induced liver damage in
wistar rats. The experiment was carried in three phases. In Phase I, the
hepatoprotective activities of the methanolic extract of the leaves was determined by
assaying for some liver function indices (AST, ALT & ALP) on acetaminopheninduced liver damage in rats. In phase II, the methanolic extract of the leaves was
further fractionated with chloroform, ethylacetate and n-butanol to obtained
chloroform, ethylacetate, n-butanol and residual extracts respectively; and the effect
of these fractions on liver function (AST, ALT & ALP) was determined.