Acute biphenotypic leukemias (LAB) are defined by the presence on the same blast cells membrane and cytoplasmic markers belonging to at least two different hematopoietic lineages. We report the case of an infant of 22mois with LAB highlighting the capital interest of hematological cytology, immunophenotyping and cytogenetic study.

To investigate the acute toxicity and antidiabetic potentials of various extracts of the leaves of Ficus sur Forssk on alloxan-induced diabetic rats. Powdered leaves were successively extracted with n-hexane, chloroform and 70% ethanol for three consecutive days respectively and the obtained extracts were assessed for phytochemicals, acute toxicity and antidiabetic activity on albino rats. The acute toxicity was assessed by Lorke’s method. Diabetes was achieved by intraperitoneal injection of alloxan monohydrate (120mg/kg). Blood glucose was determined daily for seven days using a glucometer. On the seventh day of treatment, blood samples were obtained and the serum triglycerides (TG), total cholesterol (TC), glycosylated heamoglobin (GH), urea and high density lipoprotein (HDL) were determined. The active N-hexane fraction was further fractionated by column chromatography packed with silica gel G (60-80mesh) eluting with gradient mixture of n-hexane, dichloromethane and ethanol. The phytochemical screening revealed the presence of terpenoids, tannins, flavonoid and carbohydrates. The lethal dose (LD50) was recorded at 2154mg/kg in the toxicity study. The n-hexane extract showed the highest significant (p<0.05) reduction of 77.7% in blood glucose which was comparable to Glibenclamide (78.3%). Further fractionation yielded five fractions (F1-F5) in which fraction F4 and F5 were the most active with 54.7 and 55.9% reduction of blood glucose. The lipid profile of fraction F4 also exhibited decrease in TG, TC, GH, Urea and increase in HDL. This study reports the LD50 of F. sur to be2154 mg/kg and further confirms its ethnobotanical use of in the treatment of diabetes mellitus and its potential in preventing cardiovascular diseases

Dengue virus (DENV) is the most common mosquito-transmitted human flavivirus worldwide, and it is well-established that DENV and Zika virus are closely related, resulting in substantial antigenic overlap. The infection is caused by any of the four dengue virus (DENV) serotypes transmitted by Aedes aegypti and albopictus mosquitoes. Despite the public health relevance, data on the prevalence of DENV infections among febrile patients in Jos, North Central Nigeria are limited. We aimed to determine the sero-prevalence of Dengue virus infection among febrile patients. Cross sectional study was conducted among 118 participants presenting with pyrexia at the Jos University Teaching Hospital. Participants who were malaria negative using rapid diagnostic tests (mRDT) with specific symptoms defined as probably dengue by WHO (fever and symptoms such as headache, rash, nausea/vomiting, joint pain, fatigue, retro-ocular pain and haemorrhage) were screened for dengue immunoglobulin G and M (IgG and IgM) using Dengue NS1 Antigen and IgG/IgM antibody duo panel RapiCardTM InstaTest and ELISA-based kit.

Melkersson Rosenthal Syndrome (SMR) is a rare orofacial granulomatosis of controversial etiology. It combines recurrent facial palsy, upper labial edema and a plicated tongue. Through a case of SMR we recall the clinical and therapeutic peculiarities of this pathology. 36-year-old patient, who presented in our consultation for labial and gingival edema of progressive worsening, evolving by outbreaks for five years. The interrogation reveals in the antecedents the notion of transient facial paralysis. Examination shows prominent lip edema in the upper lip, edema and superior gingival hypertrophy and a plicate tongue. The diagnosis of SMR was retained. Patient was put on prolonged corticosteroid treatment in degressive dose, which led to a clear clinical improvement with disappearance of the edema not recidivism after a decline of nine months. The SMR is an orofacial granulomatosis manifested by a symptomatic triad: recurrent paralysis or facial paresis, macrochelitis and a plicate tongue. This triad is rarely complete, and some minor signs can be observed. The diagnosis is mostly clinical and confirmed by histology. But a non-contributory histological analysis should not reject the diagnosis of SMR when the clinical symptomatology is obvious. Systemic corticosteroids are the most recommended treatment. It improves the quality of life and avoids or space recurrences. The prognosis remains good

Abstract: The effect of toxic chemicals on aquatic lives has been a problem in many communities and populations around the world today. Ekerekana and Okochiri communities in Okrika local government area of Rivers state Nigeria, whose river channel is a receptacle to Nigeria National Petroleum Corporation Port Harcourt Refinery’s effluent is not an exemption. It is perceived that this effluent has a negative ecological and human health impact on the affected communities. This study involved the use of Histology as a biomarker to tackle these environmental problems. The ecotoxicological study was carried out in Ekerekana (EKE station) and Okochiri (OKO station), while an aqua-culture centre – African Regional Aquaculture Centre (ARAC) at Buguma, Rivers state was used as the reference or control site. This followed a gross anatomical study of harvested fishes by applying a condition Factor (CF) equation and a fish health assessment index (HAI) protocol. Histological assessment protocol in a qualitative and semi-qualitative scenario was also done. The Environmental Water Quality Index (EWQI) result for the experimental sites were poor (10.5) and marginal (57.5) for EKE and OKO respectively. Sediment quality show elevated Pd. A comparative fish study shows: no significant difference for CF in ARAC (4.62) and OKO (6.65); HAI was better in ARAC (16.0) than OKO (55.5). This study was ecologically relevant; it revealed that Ekerekena and Okochiri creeks are contaminated with a moderate level of pollution.

In the era of digital technology, technology has developed rapidly however the information technology security lags drastically. There has been increase in risk and threats to the organization’s information. For every organization, information is a valuable asset and therefore has to be kept safe and secured. Employees are mainly responsible for security risks and threats. Organizations should give attention to the common vulnerabilities and mistakes which employees tend to make and moreover these should be addressed through awareness training programs. Information security awareness training is essential for every organization that uses technology. The study explores the importance of information security awareness training and the challenges faced by organizations is implementation of information security awareness training program. Information security training program protects the confidentiality, integrity and availability of the organization information. This study will assist management to provide effective security awareness training to technology users and enhance the safety and security of information.

This paper considers how the kotoki (political Interpreter) adopted by the Ahoms kings and later adopted by the British to deal with the various hill tribes of Arunachal Pradesh became one of the important element in the Nyishi traditional system. Here I tried to highlight the growth and development of kotoki and its mere role as a messenger to becoming a decision making body in the Nyishi Village Council. The paper focuses on the how the kotoki served as a bridge between the outsiders and Nyishi, which helps in understanding the culture, customs and traditional practices of the Nyishi. It also deals how the Nyishi after remaining isolated for so long gradually opened up to the outsiders though with much intricacy.

A simple and sensitive spectrofluorimetric method has been developed for the estimation of Gefitinib in pure and pharmaceutical dosage form. Gefitinib exhibits maximum fluorescence intensity in ethanol and Beer’s law was obeyed in the range of 1-3.5 µg/mL at an excitation wavelength (λex) of 280 nm and an emission wavelength (λem) of 512 nm. Stability studies with respect to time and temperature were also carried out. The results obtained were in good agreement with the labeled amounts of the marketed formulations. This method has been statistically evaluated and found to be accurate and precise

Abstract: The experiment was conducted at the Agronomy Farm, Sylhet Agricultural University during November 2012 to February 2013 to know the performance of pea varieties under rice-based relay and conventional tillage cropping systems. There were two sowing methods; i. Relay with transplant aman rice and ii. Conventional through land preparation after harvest of transplant rice and four pea varieties; i. BARI motoshuti-1, ii. IPSA motorshuti-1, iii. Jhikorgacha local and iv. Natore local as treatments in the experiment. The experiment was conducted in a split plot design assigning sowing methods in the main plot and varieties in the sub-plots. The results revealed that the highest green pod yield (3333 kg/ha) was obtained from Natore local and this was statistically at par with that of Jhikorgacha local (3234 kg/ha) in the relay cropping system. The lowest green pod yield (1745 kg/ha) was obtained from BARI motorshuti-1 under conventional method of sowing. Due to lower number of pod/plant all varieties produced lower green pod yield in spite of higher plant population/m2 in the conventional sowing method. Natore local motorshuti produced the highest fodder yield (4055 kg/ha) under relay cropping system which was significantly different from the others and BARI motoroshuti-1 produced the lowest (2220 kg/ha) under conventional sowing method. The maximum gross return (Tk 1,74,760 /ha) was obtained from the variety Natore local followed by Jhikorgacha local (Tk 1, 69, 218 /ha) in relay cropping system. Similar trends were found in case of gross margin.

Despite deviant workplace behavior has increasingly become a serious problem in today’s organizations and has been reported to significantly affect on both individual and organizational effectiveness and performance, numerous organizations have ignored and not yet prepared to cope with this problem seriously. This present study aims at enhancing the body of knowledge in the area of workplace deviance by exploring the differences between employees and employers at a selected government bank in Thailand. A sample of 143 respondents was gathered for data collection through a modified version of deviant workplace behavior questionnaire. Results of independent samples t-test analysis indicated the significant difference in employees and employers with respect to deviant workplace behavior (t = -2.005, p = .047). These results suggested that employees were less likely to demonstrate deviant workplace behavior than employers. Discussion, limitations, and recommendations for further studies were also discussed.

Smartphones have turned out to be a major part of the lives of Nigerians owing to its unique capacity to combine communication and computing on mobile devices. Its evolution has made it an indispensable item in the possession of Nigerians, especially youths and elites of the older generation, as it allows for social interaction, business communication, safe storage of personal files and mobile learning among other things. Through a critical review of relevant academic studies, the article explores the evolution of smartphone in the world and how Nigerians have adopted the device. This paper argues that Nigerians adopt smartphones due to reasons such as educational needs, social communication needs, social influence and brand name and features. Some of the potentials of smartphones to the Nigerian society, as the paper posits are; knowledge sharing in work environment, improvement of social and business relationships, creation of new business dimensions and the availing of health/educational resources. Issues such as addiction, selfie syndrome, social disconnection, academic-related problems as well as health challenges were raised as the negatives from the utility of smartphones. The paper recommends that Nigerians be more disciplined with their phones when in meetings and that students should only use their smartphones to access educational materials outside the examination halls. Also, people should limit their exposure to smart phone screens to avoid visual-related problems.

Bronchogenic cysts (BC) are rare tumours in the mediastinum, but well known to thoracic surgeon. We report a case of symptomatic mediastinal bronchogenic cyst (MBC) in adult who operated on by full thoracoscopy, and we discuss a surgical technic.

The erythrocyte sedimentation rate (ESR) is a nonspecific screening test to assess elevations of acute phase proteins that occur in various acute and chronic diseases. The aim of the study was to compare the ESR values by automated analyzer against the standard Westergren’s method. The comparison was done among 450 patient’s samples. In which 90 samples showed high degree of difference because of high ESR values and 180 samples showed low degree of difference because of low ESR values. The conclusion was automated ESR estimation helped a lot in measurement of ESR values in short time, but marked difference of ESR values shown in high ESR values.

Salt consumption is essential but has a negative health impact when taken in excess. Therefore, this research is aimed at investigating the possible role of Moringa oleifera leave extract on lipids and antioxidant enzymes following salt loading. 24 male albino Wistar rats weighing between 180-240g were used for this study and were divided into four groups (n=6). They were given either normal rat feed and drinking water, high salt diet (8% NaCl diet) + 1% NaCl drinking water and/or Moringa oleifera extract (600 mg/kg b.w., orally, once daily). After six weeks of feeding, the animals were sacrificed and blood collected through standard method for analysis. The salt fed untreated rats had significant (p<0.05) increase in Triglycerides (TG) level, Atherogenic indices (P<0.05), Malondialdehyde (MDA), Aspartate aminotransferase (AST) and Alanine aminotransferase (ALT) (P<0.01). These parameters were significantly (p<0.05) reduced to near control values following extract treatment. Salt fed untreated rats were also observed to have significant (P<0.05) reduction in High density lipoprotein (HDL), Catalase (CAT) (P<0.01), Glutathione peroxidase (GPx) (P<0.05), Superoxide dismutase (SOD) and Albumin (ALB) (P<0.01), but the reverse was the case following extract treatment. In conclusion, consumption of Moringa oleifera leaf extract ameliorates the adverse effects of salt loading on the atherogenic, antioxidants and other indices thereby preventing possible outcome of cardiovascular disease, atherosclerosis and other related ailment. It is therefore being recommended for further research and possible use in the manufacture of drugs that are necessary in management of cardiac and other related ailments.

The government work report is a kind of style with Chinese characters of language expression. Therefore, when translating it, the translator must first understand the source language’s expression and analyze the discourse in order to make effective language conversion. Cohesion is one of the important methods of discourse analysis. In this paper, the author, taking 2017 government work report as an example, analyzes the application of discourse cohesion in government work report, emphasizing the importance of cultivating the ability of intralingual understanding and the awareness of cohesion in the process of Chinese to English Translation.