Allopurinol is the drug of choice in the treatment of gout It reduces the concentration of urates and uric acid in tissues, plasma and urine, while increasing the concentration of xanthine and hypoxanthine. The purpose of this study was to examine the possibility of Biowaiver study for approval of generic brands of allopurinol tablets without additional in vivo bioequivalence and, to collect information on the safety and efficacy of the different allopurinol tablet brands using simple and cost effective in vitro methods. Physicochemical characteristics comprising drug content, hardness, friability, weight variation, disintegration and dissolution were evaluated for the six brands in comparison with the innovator. Dissolution test was carried under Biowaiver condition and the data analyzed by simple statistics and similarity and difference factors. The assay results showed that all the brands had active pharmaceutical ingredient within the specified official limits except Allo-4- , The crushing strength of three brands (Allo-1-, Allo-5- and Allo-7-) was out of the specified official limits, all the brands were complied with the specified limits For disintegration test, all the brands met the specified limits that stated by USP 32 for dissolution test , and according to f1 and f2 values, all the brands were similar to the innovator except Allo-4 and allo-6. From these results we can conclude that all the brands were met the specified limits for the physical tests, there is a failure of 9 % for content percent, and the brands were not accepted for Biowaiver under WHO criteria

Today, Kenya Government is pursuing Vision 2030. Kenya Vision 2030 is the country’s new development blueprint covering the period 2008 to 2030. It aims to transform Kenya into a newly industrializing, “middle-income country aims to ensure gender equity in power and resource distribution and increase participation of women in all economic, social and political decision making process. Further more education may also contribute to raising the quality of the labour force and hence increased productivity within a lifespan. The purpose of the study was to carry out an in-depth analysis on performance of women with that of men in relation to equity to University learning resources. Second to examine alternative strategic plans for enhance university student performance in science, mathematics and technology programmes. The theory used in this study was Liberal feminism. It is rooted in the tradition of 16th- and 17th-century liberal philosophy, which focused on the ideals of equality and liberty. The research design used in this study is ex post facto. The study was carried out in 3 Kenyan public and 3 private universities. Chi-square statistical test was used to establish relationships and variable traits while themes were derived from narrative data. The findings of this study revealed that in lower levels of education tier boys outdo girls in SMTs in terms of performance. However, at university level, men and women perform equally well. Contrary to general misconception that transition of women is not at same the rate as men, the study has shown that the difference is insignificant. The study has also established that there is no correlation between gender and preference of SMT programmes at university level. Government should set aside lots of capital to equip the SMTs facilities at all the universities.

Teicoplanin induced leukopenia is rare. This case report for 34 years old patient known case of sickle cell anemia diagnosed as osteomyelitis with two episodes of decreased WBC after initiating teicoplanin to cover MRSA strains. WBC increased after drug withdrawal in both episodes. These leukopenias were drug related.

This paper aims to investigate the effect of gender and nationality of 9th and 10th grade students in public and private schools of India, Pakistan and Zimbabwe on their achievement in mathematics based upon achievement data (n=5996) for session 2012-2013 which was gathered manually in 2013 from the participated schools of all the countries (India, Pakistan & Zimbabwe) where each country contributed 2000 sample of students collected from 20 schools and data of four students from Zimbabwe was lost, so total sample of the study was 5996 students. The influence of public and private schools was also examined on students’ achievement for the total sample. Data was analyzed by using t-test, analysis of variance and results of the study indicated that significant differences existed on the mathematics achievement of public and private school students of all the three countries and private school students achieved better in mathematics than public school students indicating private school students still achieve better than students of public schools. Besides, male and female students in public and private schools of each country achieved equal in mathematics indicating no gender disparity even in public and private schools which provides new insight that male and female students achieve equal in public schools as well as in private schools, although, private school students achieve more scores in mathematics than public school students. In addition, analysis of variance indicated that Indian public school and private school students achieve more than students of other two countries. Indian male students of public schools achieved more than public school students of Pakistan and Zimbabwe. Similarly, performance of Indian female students of public schools in mathematics was better than Pakistan and Zimbabwe public school students. Furthermore, both male and female students of private schools of India achieved better in mathematics than male and female private school students of Pakistan and Zimbabwe. Findings show that there was no gender disparity in public and private schools of the examined countries while nationality had significant effect on mathematics achievement of students as Indian students achieved highest in public and private schools than students of other two countries.

This research aims to analyze the partial effect of Perceived Usefulness on Attitude toward Using, Perceived Ease of Use on Attitude toward Using, Perceived Trust on Attitude toward Using and the simultaneous influence of Perceived Usefulness, Perceived Ease of Use, and Perceived Trust on Attitude Toward Using. The population of this research is regular customers of Ikens Group wholesalers who have downloaded and installed Ikens wholesale mobile apps which spread throughout Indonesia and currently have 320 subscribers. The number of samples is determined by using Slovin formula at 5% error rate which is 178. The quantitative analysis method is by using equation analysis of multiple linear regressions followed by simultaneous test (F-test), partial hypothesis testing (t-test), and determination analysis (R Square) with a 5-percent alpha (0.05). Before the regression test, data quality and classical assumption tests were performed first. The tool for analysis is by using IBM SPSS Statistics software version 23 for Mac. The result of this research shows that the Perceived Usefulness has a strong effect on the partial Attitude Toward Using, the Perceived Ease of Use has an moderate effect on the partial Attitude Toward Using, the Perceived Trust has a strong effect on the Attitude Toward Using, as well as the simultaneous Perceived Usefulness, Perceived Ease of Use, and Perceived Trust influence the Attitude Toward Using of mobile application (m-Commerce) Ikens Group Jakarta, Indonesia.

Islamic political thought has remained the most contentious subject from the 7th century C.E. of Islamic civilisation. The thought witnessed the diverse interpretations throughout the ages. During Medieval Islamic history hereditary succession, decline in spirituality, and alien influences in socio-political thought and cultural affairs of Muslims obliged Muslim political thinkers to come forward in order to present an appropriate political thought of Islam in their respective ages, so that the legacy of Islam would be maintained.

Gentamicin remains a first line therapy for many severe infections. Its use is associated with a low rate of resistance; moreover, it is inexpensive. Data from medical literature reveal an increase in the incidence of acute renal failure associated with the use of aminoglycosides antibiotics. Presented is a case or a 41-year-old male with a history of liver cirrhosis who developed acute renal failure one week after initiating gentamicin therapy for the management of cellulitis

The Fibonacci sequence is famous because it’s have amazing and great properties. In this study, we prove some of the interesting properties which include the relations between Fibonacci numbers and (9, 19, 29). And we found a lot of connections between them.

This study was descriptive cross-sectional study, aimed to study the effect of nutritional status, and lifestyle habit among type 2 DM patients in Surman, Western-Libya. A total of 130 type 2 DM patients were enrolled in this study, which was carried out in the period from March to (July 2017). The results were showed that, from 130 type 2 DM patients were recruited for this study, 53 (40.8%) were males, while 77 (59.2%) were females. Out of 130 participants, 47 was normal BMI (36.2%), while 81 was overweight (62.3%) and only 2 was underweight (1.5%). This study was revealed that from 130 participants of type 2 DM patients 88 have taken an ideal diet (67.6%), while 42 were not (32.4%). Moreover, only 37 patients were done physical activities (28.5%), while 93 patients were not (71.5%). Also, the study was shown that 81 patients were exposed to mental stress (62.3%), whereas 49 their life was normal (37.7%). The conclusion, the nutritional status, and lifestyle habit have a great advised effect among type 2 DM patients in Western Libya. It can be concluded that the majorities of individuals with type 2 diabetes were overweight, due to lack of physical activity, and did not follow dietary guidelines for fats, fruits and vegetable consumption. Additional measures are needed to encourage regular physical activity and improve dietary habits in this population.

The importance of soil resources to attain sustainability in crop production, eco-development and protection of environment is an established fact. Management of soil on a scientific basis is essential for sustained and increased agricultural production, on this prime perspective a study on physiochemical characters of soils has been conducted in the Talapilli Taluk of Thrissur District, India. Talapilli is the agricultural dominant area in the District and hence the study help in more understanding of the quality of the soil for proper management practices in agriculture and other sectors as well. The physiochemical characters analyzed in the study are texture, soil depth, slope, erosion, pH, electrical conductivity, primary nutrients like available nitrogen, phosphorus and potassium and secondary nutrients like magnesium and sulphur. The result indicates that Talapilli has gravelly clay loam and gravelly sandy clay loam soils in higher proportion having moderate to deep soil depth with moderate slope and less to moderate intensity of erosion. As far as chemical composition is concerned in Talapilli Taluk major proportion of soil has pH ranges from 5.1 to 6, that which shows the acidic nature of the soil. The nutrient status is appreciably good in the Taluk except few places in the Taluk that is in the centre, north and northeast of the Taluk. To consider the nutrients in specific available nitrogen and potassium is medium in the Taluk among primary nutrients and magnesium is low and sulphur is high among secondary nutrients.

The performance of personnel of KODAM I / Bukit Barisan communications unit is influenced by many factors. This research analyzes the influence of Leadership, Work Discipline, and Organizational Commitment to Personnel Performance either partially or simultaneously. Population in this research is personnel of transportation unit KODAM I / Bukit Barisan which amounted to 78 personnel. Because the population in this study is less than 100 people then in this study the sampling method using the census method, meaning that all the population sampled in this study. The technique of data analysis using multiple linear regression equation, and continued by testing R Square and hypothesis testing partially and simultaneously with t test and F test. Data analysis tool with SPSS application 23.00. The results showed that Leadership, Work Discipline and Organizational Commitment have positive and significant effect on Personnel Performance either partially or simultaneously. From the results of determination analysis there are other factors that influence the performance of personnel in addition to variables Leadership, Work Discipline and Organizational Commitment. The better the leadership, the Work Discipline and the Organizational Commitment, the better the performance of the personnel of the KODAM I / Bukit Barisan communications unit.

The aim of this study was to compare three types of commercially available brackets for corrosion susceptibility after immersing them in artificial saliva. A total of 360 brackets were used. The brackets were divided in to four groups (Control Group X and Experimental Groups A, B and C). The experimental groups were divided on the basis of duration of immersion in artificial saliva of pH 6.75 ± 0.15. Each group was divided in to corresponding subgroups. The bracket surfaces were analysed using UV –Visible Spectrophotometer and Small Angle Xray Scattering (SAXSS). ANOVA (Analysis of One Way Variance) was used for group comparisons. For post hoc comparisons Newman-Keuls multiple posthoc procedure was applied. Leone and Nu Edge Cr- Co brackets showed progressive signs of corrosion and leaching of Fe and Mg ions after immersion in artificial saliva. Discovery SL brackets showed no signs of corrosion. Leone and Cr-Co Nu Edge are susceptible to corrosion activity in comparison to Discovery SL brackets.

Literature has confirmed the bitter melon is useful to reduce the levels of blood glucose. A functional food was developed by extracting critical ingredients from bitter melon with advanced techniques. The new ingredient was generally termed as bitter melon peptide, of which had been used as major component of the product in this research. Purpose of this research is testing the effectiveness of this new product in controlling the blood glucose levels of the diabetes mellitus (DM) patients. As a preliminary study, 25 samples were recruited on the basis of volunteer through the participated pharmacies, 52% are female and 80% are aged 45 and above. After a three months period of experiment, the data indicated significant differences in the values of HbA1c and FG between starting (T0) and second month (T2), and T0, and the third moth (T3). The test concluded that the product was effective in reducing blood glucose.

The aim of this study was to evaluate the dental students’ perceptions toward the use of social media (Twitter) in an orthodontic course and the impact of this technology for teaching and learning. An online questionnaire was developed to evaluate 4th year students’ knowledge, use, and perceptions of Twitter for teaching and learning in an orthodontic course at Riyadh Colleges of Dentistry and Pharmacy. 85 of the students completed the questionnaire. Of the respondents, 75% reported having used Twitter on a daily bases. 58% of them they didn’t think that they will like the use of twitter for teaching. After their experienced it, 82% they liked it. The students perceived the Twitter sessions as enjoyable and reported it improved their engagement in orthodontic class. The results of this study indicated that students agreed that the use of Twitter had enhanced the learning environment in the orthodontic course.

Copra is one among the coconut products, the kernel of the fruit of the coconut palm (Cocos nucifera). Copra is valued for the coconut oil extracted from it and for the resulting residue, coconut-oil cake, which is used mostly for livestock feed. Copra export occupies significant position in terms of quantity as well as value position in export earnings among the coconut products. In recent years, there have been ups and downs in export of copra from India. In this study was conducted to analyze export performance of copra in India. The required data collected for the period of 10 years. The annual common growth rate in terms of quantity and value were positive. Estimates trend of copra of quantity and value in India for the period of 2006-07 to 2015-16. It was resulted that the slightly fluctuated. On the basis of fitted trend. The growth was analysed the direction of causality between time and quantity, value of copra export. The findings indicate a strong relationship between the dependent and independent variables.