Software has frolicked an increasing significant role in methods acquisition, engineering, development, mainly for large complex systems. For such systems, accurate estimates of the software costs are a perilous part of effective software management. The preparation of forecasting the cost of the software has evolved, but it is far from perfect. Constructive cost model is the most widely used among all the models available. The proposed model focusses on data set obtained from 91 models nick named as “Maxwell”. The projected model is tested and the test results from the neural network are matched with that of COCOMO model. From the experimental results, it is concluded that the amalgamation of the proposed model for the “Maxwell” data has proved better than the existing COCOMO and another model as obtained from literature.

Ethanolic root extract of Solanum torvum Sw (Family: Solanaceae) was evaluated for its antihyperglycemic and antilipidemic activity in streptozotocin induced diabetic rats. The extract was given orally in two different doses (200 and 400 mg/kg) for 28 days. Metformin (2.5 mg/kg) was used as a standard drug for activity comparison. Various parameters studied were blood glucose concentration, serum lipids, glycosylated haemoglobin and liver glycogen. The extract showed significant antihyperglycemic activity in dose dependent manner. Further, the extract was favourably and significantly corrected the alterations in the values of the lipid parameters, organ weights, liver glycogen and glycosylated haemoglobin content in diabetic rats. Therefore, it may be suggested that the ethanolic root extract of Solanum torvum has potential ability to prevent the secondary complications of diabetes mellitus like atherosclerosis.

Projects are a means by which new and improved products and services can be delivered. In today‟s digital, real-time marketplace, it is important that organizations are able to deliver products and services to market as quickly and efficiently as possible. A sequential approach to project delivery does not support change and is perceived as cumbersome and slow to deliver. In contrast, agile project delivery is adaptive and flexible. The agile approach to project delivery supports a differing mindset. A mindset that is focused on growth and delivery, in short manageable components, embracing and not rejecting change. Working within an agile project delivery framework is different, and requires project team members and participants to embrace a new way of working. A way of working that is focused on delivery through collaboration, and less of an emphasis on documentation.

H pylori infection is well known to be the most common human infection worldwide on the basis of the fact that approximately 50% of the worldwide populations are infected and that human beings are the main reservoir. Infection is more prevalent in developing countries, and incidence is decreasing in Western countries. Moreover, it has been proved to be associated to endocrine system regulation of various hormones in the body, prolactin (PRL) is one of the reproductive hormones, which is secreted by the anterior pituitary gland. The biological actions of prolactin hormone are Lactotrophic effects, metabolic effects influence to action of other hormones, osmoregulatory effects, and Influence of prolactin on the immunological system. This study was conducted in Khartoum State at the period from December 2015 to May 2016, and aimed to determine the possible effect of H. pylori infection on serum prolactin levels in Child-bearing females age (15 – 45). Sample size was 50 females infected with H. pylori and 50 uninfected females as control group. Stool Samples were taken from the entire study subject (100) samples to confirm the results of H. pylori Ab ICT in serum. The stool samples were analyzed by using H.pylori stool Ags detections ICT. Serum prolactin level was measured by using Cobas e411chemistry analyzer, the results showed that Prolactin concentration was higher in the patients compared with controls. In this study hyperprolactinemia due to H.pylori infection was reported in 52% of the patients. Statistical analysis showed that there was significant difference in the mean of prolactin concentration between infected and uninfected females group (P= 0.000). Regarding correlation between prolactin concentration and subject’s age, H. pylori infection duration or recurrence of infection, no significant was found to be observed.

The article analyzes the importance of marketing knowledge in the implementation of the Vilnius College / University of Applied Sciences project "Ukrainian Studies Platform (demobilized soldiers of the Ato area)". Analyzing the importance of marketing and entrepreneurship knowledge for Ukrainian soldiers, marketing research, creating new businesses. Entrepreneurship involves not only the knowledge and skills that are needed independent business creation and development (marketing, financial management, business management knowledge and skills, etc.), but the various knowledge and abilities needed to rationally and economically deal with various professional and personal life problems and related situations with employment, job search, professional career, decision of professional tasks, topical solving public problems. Important elements of entrepreneurship are ingenuity, openness to innovation and ability to apply creatively new solutions, ability to evaluate the costs and potential benefits of implementing the solution [18].

Periodontitis are multifactorial infections that begin with a period of inflammation of the supporting tissues of the teeth and then progress destroying the tissues until loss of the teeth. The goal of periodontal treatment is to stop the progression of the disease, restore functions and regenerate the damaged tissue. However, regeneration of different tissues, by conventional treatments, still remains great challenge. To address this, there are several approaches to tissue engineering for regenerative dentistry, among them, the use of stem cells by including dental pulp stem cells (DPSCS), periodontal ligament stem cells (PDLSCS), stem cells from the dental apical papilla (SCAPS), stem cells from human exfoliated deciduous teeth (SHEDS), dental follicle stem cells (DFSCS), dental epithelial stem cells (DESCS), bone marrow mesenchymal stem cells (BMMSCS), adipose-derived stem cells (ADSCS), embryonicstem cells (ESCS) and induced pluripotent stem cells (IPSCS). This novel approach may represent an effective therapeutic tool for periodontal regeneration. However, there are still obscurities regarding the mechanisms underlying in periodontal regeneration and challenges in applications of dental stem cell. Further efforts are necessary before moving to clinical trials for future applications.

The purpose of this study is to obtain information about the effectiveness of illustrated religious stories in developing early childhood moral intelligence. The research was conducted in Raudhatul Athfal (RA) al-Akhyar Muara Bungo, Jambi Province. In this research, the researcher has used Action research method with Kemmis & Mc Taggart model, which includes four stages of planning, action, observation, and reflection. The subjects of this study were 20 children of RA. The study was conducted in two cycles consisting of three meetings in each cycle. The technique of data collection is done through observation, interview, and documentation. In analyzing the data, the researcher used quantitative and qualitative approach. Quantitative analysis uses percentage and frequency tables to see changes in a score of achievement level of moral intelligence while the qualitative analysis uses Miles and Haberman model analysis. The results show that the moral intelligence of children can be enhanced through religious picture story. Before the action of moral intelligence, the child is in the category of developing the category of growth in the second cycle. The results provide the implications for schools or developers of moral creativity in early childhood.

Despite widespread use, little is known about the risk associated with insecticides exposure to human health hence, this study. 48 wistar rats (90-120g) were randomly grouped into six (n=8). All except Normal control (NC) were exposed to domestic insecticide fumes once every 48 hours. Group 2, insecticide control (IC) was exposed to (20% of 81.55mg/m3) 0.20mg/ml of DAKSH insecticide. Group 3, positive control (PC) was treated with a standard testosterone drug-Nugenix. Groups 4, 5 and 6 received 400mg/kg b.w each of crude extract (CE), ethylacetate and n-hexane fractions of Vernonia calvaona (VC) daily via orogastric intubation for 21 days. After administration, animal sacrifice and blood collection was done via cardiac puncture for analysis. The result presented a significant decrease (p<0.05) in testosterone of IC group compared to NC. Groups 3 and all treated groups effected progressive increase in testosterone concentration compared to IC group. FSH was significantly reduced (p>0.05) in IC and n-hexane fraction of VC compared to control. However, nugenix treated and ethylacetate fraction caused a remarkable increase in FSH compared to IC. WBC was significantly decreased (p<0.05) in IC and n-hexane groups compared to control. The Crude Extract treated group significantly increased WBC count compared to IC group. Histopathological studies of the testes showed varied levels of histological derangements in IC while Ethyl acetate treated group showed highest regenerative ability. This study revealed that insecticides adversely affected male gonads while the extracts showed ameliorative effects with the highest effect seen in ethyl acetate fraction in managing the insecticide induced damage.

Abstract: Hypertensive disorders of pregnancy are the most common but a leading cause of maternal and perinatal morbidity and mortality. The present study was done to identify the possible risk factors for the hypertensive disorders of pregnancy. This hospital based case-control study was done on 250 normotensive and 250 women with hypertensive disorders of pregnancy were included after obtaining informed consent. Data were collected on socio-demographic profile, obstetric history, history of hypertension in previous pregnancy, family history, pre pregnancy weight, height and BMI. Data were entered in the MS Excel sheet and statistically analysed. Odds ratio with 95% confidence interval was used to calculate impact of different variables on the risk of presenting hypertension. The occurrence of hypertensive disorders in pregnancy was found significantly higher in the age group ≥30 years, nulliparity or Primipara, family history of hypertension and history of hypertension in previous pregnancy. Women with history of stillbirth were 5 times more at risk of having hypertensive disorders of pregnancy. No statistically significant relationship was found between hypertensive disorders in pregnancy with educational status, religion, residence and socioeconomic status, gravidity and history of abortion. Identifications of risk factors for hypertensive disorders during pregnancy will help in planning treatment of hypertension and preventing complications through regular antenatal check-up.

Wounds are a significant cause of morbidity worldwide, studies show that for every million wound patients, at least 10.000 die from microbial infections. The skin is a vital organ that serves as a protective barrier between the human bodies on its external environment. Staphylococcus aureus has been known as a cause of deepseated wound infection for close to a century, having recognized as a cause of nosocomial infection and super infection in patients receiving antimicrobial agent such as surgical cases. MRSA colonizing the anterior nares and skin of human are the major sources of surgical site infection as well as nosocomial spread. Methicillin-resistant Staphylococcus aureus (MRSA) are bacteria resistant to penicillin and cephalosporin classes of antibiotics and are often resistant to many other classes of antibiotics. Importance of S. aureus as persistent nosocomial and community acquired pathogen has become a global health concern. The aim of this study to determine the frequency and antibiotic susceptibility pattern of S.aureus isolated from wound infected patient attending Wad Madani Teaching Hospitals. Two hundred samples collected from patients with infected wound at the period from April to July 2016. Out of 200 samples examined, 60 (30%) isolates of S. aureus obtained, 116 (58%) other bacterial species and 24 (12%) samples showed no growth. The highest isolation rate of S. aureus 60% occurred among age group (41-60) and according to gender 32 (53.3%) S. aureus isolated from male and 28 (46.7%) from female. The overall profile of susceptibility pattern showed that vancomycin and linezolid were more sensitive (100%), amoxicillin and penicillin were the least sensitive (10%) and (36%) respectively. The result of the study showed that frequency of S. aureus isolated from infected wounds 60 (30%) and vancomycin and linezolid are more effective in the management of S. aureus in this locality.

Sympathetic & Parasympathetic test status may be changed during follicular and late luteal phases of menstrual cycle due to fluctuations of serum estrogen and progesterone levels. Objective is to find out. Sympathetic & Parasympathetic tests between male medical students & luteal phase of menstrual cycle in female medical students. This study evaluates autonomic function tests in different phases of menstrual cycle and concludes that sympathetic activity is highest during luteal phase and lowest in the follicular phase. It is concluded that there is higher sympathetic activity in males as compared to females

Impaction of maxillary central incisors are only seldom encountered in clinical practices. Impaction of permanent anterior teeth results in both aesthetic impairment and functionally compromised occlusion. Careful planning and interdisciplinary approach are required for the successful management of impacted central incisor. The present case report highlights a case where patient reported with a missing left central incisor, at the age of 9 years and 2 months. A palpable crown prominence on labial gingival mucosa in the vestibule was suggestive of the impacted maxillary central incisor. On Cbct examination 21 was located below the nasal floor with long axis of the tooth near parallel to palatal plane. The crown of the impacted 21 faced labially at the level of middle third of the root of 11. The root formation was incomplete. The crown of the impacted teeth was exposed with the help of a diode laser under LA. A lingual button is bonded on the palatal surface of the exposed crown. PAE brackets are bonded to 12, 11 and 22 with slot alignment. E- thread is tied from the monkey loop from the attachment of exposed crown to the 0.018 special Autsralian base archwire. Traction was progressively continued till a PAE bracket could be bonded followed by a piggy back traction by 0.014 Niti. Case was finished with disimpacted 21 in alignment with the arch. Disimpaction and alignment of incisor achieved by a minimally invasive technique was successful and showed good stability.

The prevalence of nutritional deficiency especially the iron deficiency anemia is very common in pregnant females of developing countries, more so in the rural and tribal population. We in the present study tried to evaluate the prevalence of anemia in 300 females in 1st, 2nd and 3rd trimester attending ANC in Rajiv Gandhi Institute of Medical Sciences and Hospital [RIMS], Adilabad. The Institutional Ethical committee permission was obtained for the study. 100 patients in each of the three trimesters were included in the study all the pregnant ladies were healthy without any significant medical disorders. The blood samples were collected from the peripheral vein in 5ml vacutainer and send to the Department of Pathology for examination. The Department of Pathology, RIMS Adilabad uses 5 part hematology cell counter (Sysmex Xn 1000 manufactured by Sysmex India Pvt. Ltd Mumbai) to obtain all the hematological parameters. The mean levels of hemoglobin in n=100 patients of 1 trimester were 8.38 ± 1.5 gm/dl, the mean levels of Hb in n =100 patients of 2nd trimester was 8.34 ± 1.24 similarly the mean Hb levels of n=100 patients in the third trimester was 7.75 ± 1.02. The hemoglobin levels of 10.0 – 10.9 gm/dl was classified as mild anemia in our study 10.83% of pregnant ladies had mild anemia. Between 7.0 – 10.0 it was classified as moderate 76.67% of pregnant ladies had moderate anemia, < 7.0 gm/dl was classified as severe 12.5% had severe anemia and < 4.0 gm/dl was classified as very severe (decompensated) anemia no case of very severe anemia was present in this study. The presence of nutritional deficiency anemia is very common in the tribal pregnant females of Adilabad. Although all the pregnant females receive duly the dose of iron and folic acid supplementations during the Antenatal care there needs to be good nutritional supplementation provided to reduce the burden of anemia in the pregnant females of this area.

The study of Sino-African cooperation is evolving as a very significant area of research. So far, students, scholars, diplomats, journalists and other observers have produced an avalanche of works on the subject, each focusing on an aspect or aspects of the theme, from different perspectives. These differing views and perspectives convey opinions that converge and or diverge in substance and analysis, even as they enrich (and sometimes confuse) our understanding of the evolving cross continental reality. In view of this, this paper studies the theme of Sino-African cooperation with a specific focus on analyzing the issues/opinions that exist along three different schools of thought. The paper defines the perceptions vis-à-vis the underlying factors that drive their expressions, and submits that interests and changing international circumstances form the foundation upon which not only perceptions are made, but how responses are constructed.

There are limited study of the risk factors and clinical characteristics of patients presenting with myocardial infarction (MI) at a young age in India. To study clinical profile of young patient with MI in India. The young MI patients were more likely to be male (80%), with high BMI (31 kg/m2), with a family history of premature coronary artery disease (49%) and to be current smokers (57.1%). 36% patients had none or only one traditional risk factor for MI. Male gender, Smoking, obesity and a family history of premature coronary artery disease being particularly prevalent in young MI patients