There is some controversy about assessment of nodal stage in staging systems used for gastric cancers. The goal of the this study is to assess the influence of metastatic lymph node ratio (MLNR) and number of resected lymph nodes on survival in patients with gastric cancer who were perfomed R0 resection due to gastric adenocarcinoma. Data from 125 patients with gastric carcinoma who underwent R0 resection due to from 2009 to 2015 investigated retrospectively. Cut-off values used for MLNR were 0.1-25%, 26-50% and >50%. Sex, age, size and location of tumor , differentiation, tumor invasion, lymphovascular invasion, number of metastatic lymph nodes and MLNR were analyzed as prognostic factors. Five-year survival rate was 45.6%. Five-year survival rates among patients with pN0, pN1, pN2, pN3aand pN3b disease were 79%, 41%, 34%, 25% and 17%, respectively (p=0.0001). Five-year survival rates among patients in MLNR0, MLNR1, MLNR2 and MLNR3 categories were 79%, 42%, 28% and 5%, respectively (p=0.0001). Due to our results, tumor size, differentiation degree, depth of invasion, presence of lymphovascular invasion, number of metastatic lymph nodes, MLNR and disease stage were found to be associated with survival (p=0.0001). According to results of multivariate analysis, differentiation degree, presence of lymphovascular invasion and MLNR were found as independent risk factors, while number of metastatic lymph nodes was not an independent risk factor regarding survival. MLNR is an independent risk factor in gastric adenocarcinoma patients undergoing R0 resection regarding survival.

PBL goes with the trend of the times which is conducive to cultivate students' comprehensive qualities and autonomous learning ability, moreover, to stimulate their creativity, exploration and critical thinking so as to provide the society with interdisciplinary talents. This paper aims to probe into the validity of PBL method in College English reading teaching through the review of PBL theory, the contrast between traditional class and PBL class, and the PBL class design of College English reading so as to lay the foundation for further in-depth teaching and research in the future.

Chronic renal failure is increasingly health problem all around the world with a high burden of mortality and cardio vascular morbidity rate. The study is mainly directed to establish lipid profile in chronic renal failure by ascertaining the levels of serum cholesterol, HDL cholesterol, LDL cholesterol, VLDL cholesterol and triglycerides. In view of this extensive work has been done in the field and incessant efforts are being made to widen the horizon of lipid in chronic renal failure. The present study was aimed to find lipid abnormalities in chronic renal failure. There is significant rise in Triglycerides, VLDL, LDL in chronic renal failure. There is decrease in HDL concentration in chronic renal failure as compared to control. Increased concentration of Triglycerides and VLDL are the main causes for increased incidence of cardiovascular abnormalities in chronic renal failure.

Orthodontic camouflage treatment is an acceptable option for mild to moderate skeletal discrepancies for correcting the malocclusion as well as the skeletal problem. Surgical treatment is the preferred and most stable treatment for adult patients with severe skeletal Class III malocclusion. Patients with borderline dentoalveolar compensation who are not willing to accept the costs, risks, and potential complications of surgery can sometimes be treated successfully with camouflage orthodontics. It is not clear which mechanics are most appropriate or which patients are most likely to benefit from an orthodontic approach to severe skeletal Class III malocclusion. In this article a case report of a camouflage treatment in a skeletal class III malocclusion patient with prognathic mandible with average growth pattern and partially erupted palatally placed upper right canine and retained deciduous right upper canine. The aim of this article is to show that Orthodontic camouflage is an acceptable option for mild skeletal discrepancies that offers esthetic results in the soft tissues as well as correction of malocclusion.

The management of the cervical lymph nodes is an integral part of the overall treatment of the oral cavity malignancies. The indications and uses of the various types of neck dissections and pre and postoperative radiotherapy has been a subject of much debate. Based on the results of the present study and the literature available with us, we can conclude that, Dissemination of metastatic cancer to regional lymph nodes from primary sites in the upper aerodigestive tract occurs in a predictable and sequential pattern. For primary tumours in the oral cavity, the regional lymph nodes at the highest risk for early dissemination by metastatic cancer (first echelon nodes) are limited to levels 1,2 and 3, i.e., within the supraomohyoid triangle of neck. Skip metastasis to levels 4 and 5 in the absence of metastasis at levels 1,2 or 3 is very rare.

This study aimed to evaluate the effect of an educational program on nursing performance regarding advanced cardiopulmonary resuscitation. A QuasiExperimental Study. The study conducted at the emergency department at Ain Shams University hospital and children hospital affiliated to Ain Shams University hospitals. A convenience sample included all available nurses (100) , at the previously mentioned settings over a 6 months’ period. Pre-designed sheet; it was concerned with their knowledge regarding advanced cardiopulmonary resuscitation.

This paper takes Wal-mart which is the leader of Fortune Global 500 as an example, analyzing its product, place, price and promotion, pointing out a series of marketing problems War-mart has faced within the Chinese market and offering some solutions. The marketing strategies of War-mart both in China and overseas have provided significant references to Chinese retailing companies. Chinese retailing companies should learn War-mart’s successful experience during its localization in China and avoid similar mistakes, and then convert what they have learned into their own strengths and advantages.

The study empirically examined the determinants of share price in the Nigerian Stock Market from 1980 to 2000. Data from fifteen quoted companies were used. The study adopted ordinary least square method i.e multiple regression to analyse and interpret the data that were mainly sourced from the Nigerian Stock Exchange. The model used expressed the share price as a function of some identified determinant established by theories and literature. These determinants are earning per share, dividend per share, money supply, oil price, the gross domestic product, consumer price index and interest rate. After the analysis it appears that all these variables are true determinants of the share price in Nigerian Stock market going by the significance of the model at both 5% and 10% levels of significance and the robustness of the R square which stood at about 0.93. This simply shows that these identified determinants have been able to explain about 93% variation in the share price of the companies. However based on the revelations concerning the relationship of the share price and each of this variables it appears the that earning per share, dividend per share, money supply, oil price and consumer price index all exhibited positive relationship with the share price while interest rate and GDP exhibited negative relationship.

The main aim and objective of the present research work was the preliminary phytochemical screening and evaluation of in vivo anti tumour activity of mthanolic and ethyl acetoacetate extracts of fruit of Punica granatum (ME-FPG and EAAE-FPG). Acute oral toxicity of ME-FPG and EAAE-FPG were performed according to the OECD guideline 423 method. The experimental results of acute oral toxicity studies revealed that all the extracts proved to be non toxic at tested dose levels and well tolerated by the experimental animals as there LD50 cut of values > 2000 mg/kg b. w. The in vivo antitumor activity of ME-FPG and EAAE-FPG was carried out against human colon cancer cell line HT 29. The present in vivo experimental data displayed that both ME-FPG and EAAE-FPG significantly increased the PILS. While 5-FU increased the life span of 85%, ME-FPG increased it by 75% and 67.5% by EAAE-FPG respectively ME-FPG. So ME-FPG and EAAE-FPG at dose 300 mg/kg significantly improved the overall survival of treated animals in comparison to tumour control group and 5-FU was not significantly differed from each other in improving the overall survival of animals. Histopathological study displayed a greater degree of tumour apoptosis and necrosis in the ME-FPG and EAAE-FPG treated group than in the control group. In addition, PCNA showed that administration of ME-FPG and EAAE-FPG decreased the proliferation of tumour tissues. Proliferating cell nuclear antigen (PCNA) is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for replication

The study empirically investigate the nexus between agricultural financing and economic growth in Nigeria from 1983 to 2015. Augmented Dickey-Fuller (ADF) test and the Phillip-Perron tests were used to establish which variable is stationary at different levels. Almost all the variables (Real Gross Domestic Product (RGDP) Agricultural credit guarantee scheme fund (ACGSF) Commercial Bank Loan and Advance on Agriculture (CBLAA) are stationary at first different form, that is they are integrated of order I (1) except interest rate (INTR) which is stationary at level, that is, it is integrated of order I (0), hence Bounds co-integration test was adopted since it allows combination of fractionally integrated variables i.e. combines variables of different orders of integration. The results reveal existence of long-run relationship between proxy of economic growth and the proxies of agricultural financing. Meanwhile, Auto Redistributed Lag (ARDL) results show both short and long run effect of agricultural financing schemes on the growth of Nigerian economy. In addition, various diagnostic tests (such as Jarque-Bera (JB) test, Breusch-Pagan Serial Correlation (LM) test, Ramsey test, and ARCH test) were conducted to fulfill some of both Ordinary Least Square and normality assumptions. Notably, the loan disbursement mechanism adopted by agricultural credit institutions have fail to drive the Nigerian economy towards real growth despite the long run nexus among the key variables, coupled with corruption, and policy summersaults in the sector. Therefore, there is need for proper channelization of loans across board with sustainable fiscal measures that can translate to actual growth.

This paper proposed a framework to establish the relationship between the implementation of TQM success factors and the organizational performance measures, using the role organizational culture plays as a moderating variable in the oil and gas industrial sector in Libya. The study which is the first step in providing a base for the empirical study of the moderating effect of culture in the Libya oil and gas industry has put forward some key success factors for TQM implementation with special consideration of the operational culture in the oil distribution sector in the Libya oil and gas industry. Thus, the study focused on those critical factors that can easily and positively affect the organizational performance. Having proved by previous TQM researchers how organizational culture and practices significantly influence the overall organizational goal and performance, if adopted and implemented with sincerity, this study will help Libya’s Oil and Gas Sector to improve its competitiveness among firms, quality of products and services, and a standard customer expectation.

Xanthogranulomatous gastritis is an extremely rare condition and only few cases have been reported in literature. It is an inflammatory tumor like lesion usually misdiagnosed preoperatively as an advanced gastric cancer. We report one such rare case in a 68 year old female who came with complaint of epigastric pain and vomiting for 15 days. Endoscopy revealed solitary elevated nodule in the gastric lesser curvature. Clinical diagnosis was suspicious of gastric carcinoma. Histopathologically foamy histiocytes with dense chronic inflammatory infiltrate were seen in gastric wall suggestive of xanthogranulomatous gastritis

This study empirically examines the impact of economic growth and access to safe drinking water on life expectancy in Nigeria using Autoregressive Distributive Lag (ARDL) model as tool of analysis for the period 1980 - 2014. The result of this study indicates that economic growth and access to safe drinking water exert positive and statistically significant impact on life expectancy at birth. Consequently, upon the findings of this study, a number of recommendations are given which include: the need for the governments to intensify its existing policies in order to maintain inclusive economic growth that would increase employment generation and reduce poverty for better life expectancy. Moreover, there is also need for governments, Nongovernmental organizations, international development partners and philanthropists to intervene in improving access to safe and portable drinking water in both rural and urban areas through construction of boreholes, pipe water, public taps or standpipes, tube wells, protected dug wells, protected springs, and rainwater collection reservoirs.

They include Cell surface antigens; Cytoplasmic proteins, Enzymes, Hormones and most of them are proteins. They can be products of cancer cells themselves or of the body in response to cancer or other conditions. A marker represents a qualitative or quantitative alteration or deviation from normal of a molecule, substance, or process that can be detected by some type of assay. An elevated level of a tumor marker can indicate cancer; however there can also be other causes of the elevation. Thus, Tumour markers cannot be construed as primary modalities for the diagnosis of cancer. These tumor markers help in screening, diagnosing the diseased condition, staging of the disease, guiding and monitoring the treatment, to determine the prognosis and to prevent recurrence.

This study aims to test and analyze the influence of service quality, customer relationship, and customer satisfaction, and customer loyalty in PT Prudential Life Assurance. Adapataata used is the data of the 10 largest insurance in Indonesia during the last 3 years (January 2014 - December 2016). The research method used is quantitative. For sampling using Slovin formula. From population of 133 consumers of PT Prudential Life Assurance in Best One Agency Jakarta, 100 consumers met this criterion as a sample. The analytical tools used is multiple linear regression. The results showed service quality, customer relationship, and customerr satisfaction simultaneously (simultaneously) affect customer loyalty. Partially, service quality, customer relationship, and customer satisfaction have a significant positive effect on customer loyalty. And of the three variables diguanakan, customer satisfaction that has the most influence on customer loyalty.