ORIGINAL RESEARCH ARTICLE | Dec. 30, 2017
GEECA: Grid Based Energy Efficient Clustering Algorithm for Mobile Wireless Sensor Networks
K. Juliet Catherine Angel, Dr. E. George Dharma Prakash Raj
Page no 457-464 |
10.21276/sjeat.2017.2.12.1
Energy Efficiency is the critical need of Mobile Wireless Sensor Network
(MWSN) due to the limitation in the size of the device and the disability to replace
the battery of the nodes. In this paper, a Grid Based Energy Efficient Clustering
Algorithm for Mobile Wireless Sensor Networks (GEECA) is proposed to select the
Cluster Heads (CHs) thereby minimizing the energy consumption. The simulation
results are compared with a prevailing clustering algorithm, which reveals that the
proposed algorithm outperforms the existing algorithm.
ORIGINAL RESEARCH ARTICLE | Dec. 30, 2017
Analytical Method Development and Validation of Metformin Hydrochloride and Benfotiamine in Bulk and Marketed Formulations
A. Tari, Padmavathi P. Prabhu, Paramita Das
Page no 1322-1329 |
10.36348/sjmps.2017.v03i12.010
In the present work, two simple and sensitive UV spectrophotometric methods have been developed for the quantitative estimation of Metformin Hydrochloride and Benfotiamine in combination using bulk and pharmaceutical dosage forms. Method A is Simultaneous equation method which involves measurement of absorbance at selected wavelength and solving the simultaneous equation to calculate the amount of drug present. Distilled water was used as the solvent for the analysis of both drugs. Two wavelengths 230 and 246 nm were selected for the estimation of Metformin Hydrochloride and Benfotiamine. LOD for Metformin Hydrochloride and Benfotiamine were found to be 0.03µg/ml and 0.27µg/ml respectively. Method validation was done as per ICH guidelines. Method B is Absorbance ratio method which involves, formation of Q-Absorbance equation at 239 nm (isoabsorptive point) and 246 nm (λmax of Benfotiamine) in distilled water. The Linearity lies between 2-16 µg/ml for Metformin Hydrochloride and 2-18 µg/ml for Benfotiamine with r2=0.999 and 0.998 respectively. LOD for both drugs were found to be 0.16 µg/ml and 0.3 µg/ml respectively. Method validation was done as per ICH guidelines
CASE REPORT | Dec. 30, 2017
Unusual Occurrence of Compound Odontoma in Association with Impacted Mandibular Canine- A Case Report
Saha Alangkar, Sengupta Anirban, Banerjee Abhishek
Page no 310-312 |
10.21276/sjodr.2017.2.12.4
Odontomas are pathological entities of odontogenic origin. They are
mostly prevelant with impacted permanent teeth causing delayed shedding of
deciduous teeth. They are mostly asymptomatic, but on association with cystic
formation can cause discomfort to patient and esthetic concerns. This paper is a short
reporting of an incidental finding of odontoma associated with impacted mandibular
canine.
ORIGINAL RESEARCH ARTICLE | Dec. 30, 2017
Antimicrobial Potency and Molecular Mechanism of Benzothiazole Schiff Base Hybrids
Meenakshi Singh, Satheeshkumar Sellamuthu, Sudhir Kumar Singh, Mayank Gangwar, Gopal Nath, Sushil K. Singh
Page no 1360-1369 |
10.36348/sjmps.2017.v03i12.017
Antimicrobial resistance reduces the effectiveness of the standard treatment and also increases the risk of spreading the disease to others. Therefore, there is an urgent need for the development of new class of antimicrobials. In such an attempt, benzothiazole schiff base hybrids synthesised were evaluated for antimicrobial potency against E. coli, S. typhi, S. aureus, E. faecalis, K. pneumonia, P. aeruginosa, C. albicans, C. tropicalis, and C. krusei and also an attempt was made to understand their molecular mechanism of action. Some of the benzothiazole schiff base hybrids have exhibited excellent antimicrobial activity with MIC of 3.91µg/ml against S.aureus, P.aeruginosa and E.coli in comparison with the standard drug ciprofloxacin. The molecular mechanism of action of benzothiazole schiff base hybrids was elucidated in both intact bacterial cells and plasmid DNA. The potent antimicrobial activity of the hybrids may be due to membrane perturbing mode of action explicated by membrane depolarization assay and fluorescent assisted cell cytometry (FACS) study on intact bacterial cell. However, the activity may also be due to the intracellular mode of action explicated by DNA cleavage study on plasmid DNA
ORIGINAL RESEARCH ARTICLE | Dec. 30, 2017
Total Phenol, Flavonoid, Tannins, Vitamin C and Spectral Analysis of Ethanolic Extract of Spilanthes filicaulis
Eboh AS, Ere D, Frank-Oputu A
Page no 331-334 |
10.21276/haya.2017.2.9.3
Spilanthes filicaulis (Compositae or Asteraceae) is a genus comprising of
over 60 species that are widely distributed in tropical and subtropical regions of the
world, such as Africa, America, Borneo, India, Sri Lanka and Asia. The total
phenolic, flavonoid, tannins, b-carotene and lycopene content of the leaf and flower
parts of Spilanthes filicaulis were evaluated. UV-Vis spectrophotometric scanning of
leaf and flower in ethanol was also carried out. The methanolic extracts of leaf and
flower of Spilanthes filicaulis had higher phenolic, flavonoid, tannin and ascorbic
acid contents these bioactive compounds contribute to the antioxidant activity of the
plant.
REVIEW ARTICLE | Dec. 30, 2017
Unemployment and Failure of Public Enterprises: Causes and Prospects
Dr. Usman D. Umaru
Page no 1135-1142 |
10.21276/sjbms.2017.2.12.11
The study is on the rate of Unemployment in Nigeria as a result of the
failure of Public Enterprises. The objective of the study therefore is to identify the
impact Public Enterprises failure had on Unemployment rate in Nigeria. This was
achieved through the analysis of secondary sources of data and other documentary
evidences on the issues. The study discovered that the failure of Public Enterprises
in Nigeria had contributed immensely to the Unemployment rate. Conclusively, the
Privatization of Public Enterprises in Nigeria had led to massive loss of jobs due to
lack of stable trade unions that will negotiate workers disengagement or exit in
accordance with the law. The study therefore recommended that in order to provide
employment to the unemployed in Nigeria, Public Enterprises should be revamped
and managed in the spirits of State Capitalism or purely on full commercialization
basis.
ORIGINAL RESEARCH ARTICLE | Dec. 30, 2017
The Roles Appropriateness and Hierarchy on Cultural Conscience: Therapist’s Perspective
Elizabeth Sarah George, Baiju Gopal
Page no 312-320 |
0.21276/haya.2017.2.9.1
This research paper is an attempt to understand how the cultural and social
dimensions which operates in the Indian Cultural Context. The research has coined a
term called “Cultural Conscience” in order to get a clearer picture of how the various
dimensions interact and its effect on the psyche the term has been introduced. The
aim of this research is to see how these mould the psyche of the individual and it is
being explored through the perspective of the therapist. The sample size for the study
was Clinical and counselling psychologists.10 psychologists were interviewed. The
tool used for data collection was semi- structured interviews. The analysis for the data
was done using thematic analysis. Four global themes were arrived at. The global
themes identified were Identity Crisis, Identity Formation, Self- Sacrifice in Clients
and Shame and Guilt in Therapy. The manner in which the cultural factors influence
one’s way and nature of relationships that is formed with the external world is also
studied in this research.
ORIGINAL RESEARCH ARTICLE | Dec. 30, 2017
Zimbabwean Tour Operators' Structure and Information Communication Technologies Adoption
Shepherd Nyaruwata
Page no 1180-1188 |
10.21276/sjbms.2017.2.12.16
The purpose of the study is to identify the characteristics of the
Zimbabwean tour operators with a view of ascertaining how these characteristics
impacted on their adoption of information communication technologies.
Quantitative method was used to gather data for the study utilizing self administered
structured questionnaires. The study showed that the majority of the tour operators
were small and medium sized enterprises (SMEs) most of whom were family
owned. It was concluded that the size and ownership characteristics of the tour
operators precluded them from prioritizing adoption of information communication
technologies. The study recommended that tour operators need to be empowered
through ICT awareness training programmes.
ORIGINAL RESEARCH ARTICLE | Dec. 30, 2017
Oxidative Stress and Endogenous Antioxidant Vitamins: Relationship in Carbon Tetrachloride (CCl4) Induced Experimental Rats Model
Babandi A, Idachaba DA, Shehu D, Yakasai HM, MurtalaY, Gumel SM, IbrahimS, Muhammad A, Ibrahim A, Babagana K, Gadanya AM, Muhammad BY
Page no 321-330 |
10.21276/haya.2017.2.9.2
The role of oxidative stress in the pathogenesis of various diseases has
been established. Maintaining the steady balance between reactive oxygen species
and natural antioxidants is a crucial factor, and could probably serve as a major
mechanism in preventing damage by oxidative stress induced by toxic substances. A
comparative study and correlation analysis of malondialdehyde (MDA), serum
vitamins (A, E and C) and the redox active metals (Cu, Fe and Zn) in CCl4 induced
oxidative stress in albino rats with various doses of CCl4 were determined. The serum
levels of oxidative stress markers were compared between the normal and test groups.
The result showed a significant increase in the serum vitamins A and E in the CCl4
induced oxidative stress rats compared to control rats (P<0.05). However, the serum
level of vitamin C was not statistically different compared to control rats (P>0.05).
MDA correlated strongly and positively with vitamin C (r=0.94), Vitamin A(r=0.87),
Vitamin E and Fe(r= 0.90 and 0.87 respectively) while the serum MDA showed a
weak positive relationships with Zn(r=0.02) and Cu(r=0.47).Thus, the increased
serum levels of some antioxidant vitamins and the redox metals in the experimental
rats as observed in this study could be a compensatory regulation in response to
induced oxidative stress by CCl4.The evidence from this study lends credence to the
ability of endogenous antioxidants to counter the effects of free radicals generated by
hepatotoxic substances and maintain the steady-state of prooxidant-antioxidant
balance in the system.
REVIEW ARTICLE | Dec. 30, 2017
Enhancing Competencies of Shipbuilding Employees in Bangladesh: Effect of Training and Development
Md Shahid Iqbal
Page no 1059-1064 |
10.21276/sjbms.2017.2.12.3
Shipbuilding was once a flourishing trade along the coast of Bengal 400
years ago. Countries flocked to her shipyards to get the best wooden commercial
and military ships available at the time. However, with the advent of the industrial
revolution, the shipbuilders of Bengal lagged behind in the fabrication of the
primary new construction material that was sweeping the world, namely steel. As a
result of this lack of skill, Bengal rapidly lost her position amongst the great
shipbuilders in the world. Today, Bangladesh has resumed the process of inheriting
that lost heritage of shipbuilding. Being a young shipbuilding country of only 2
decades, Bangladesh has already started making ripples in the international
shipbuilding market by fetching handsome orders from as far away as Europe and
Africa. The prospects for future growth, based on industry analysis of the key
forecasting variables, can only be labelled as positive. However, a lack of skilled
shipbuilding personnel is hindering Bangladesh‟s chances in the global industry.
This policy paper has presented numerous recommendations spanning the provision
of „specialised training to foster the development of local human resource‟ to
„recruitment of foreign skilled personnel‟ as means for supplying the local demand
for skills. Additionally, joint industry action in areas such as training centres,
university course development and labour supply forecasting has been promoted.
ORIGINAL RESEARCH ARTICLE | Dec. 30, 2017
Ligand Docking Based Identification of Novel Drug Analog for an Effective Treatment against Filaria
Venkata Ramya Bola, Pasupuleti Sreenivas Rao, Sreeram Satish
Page no 335-348 |
10.21276/haya.2017.2.9.4
Filariasis (Philariasis) is a parasitic and infectious tropical disease that is
caused by thread-like filarial nematode worms and their larvae. Filariasis is rarely
fatal and it is the second leading cause of permanent and long-term disability in the
world. The larvae transmit the disease to humans through a mosquito bite.
Considering the Tubulin protein as drug target, which is the principle component of
the Microtubular system in the filarial nematodes, the drugs were found by using the
Drug Bank and their analogs by using NCI Enhanced Database Browser.
Benzimidazole carbamates, a class of microtubule depolymerizing drugs was found
to act by disrupting the assembly of tubulin dimers into microtubules. Thus the
filarial nematode muscular system gets severely affected. The Filariasis can be
prevented and eradicated by administrating one of the drugs belonging to
benzimidazole carbamates class. Using Discovery Studio Visualisation tool, the
analogs of this class of drugs were docked with the tubulin protein and novel drug
was identified for an effective treatment against Filaria.
ORIGINAL RESEARCH ARTICLE | Dec. 30, 2017
The Political Economy of Education and Educational Change in the East African Community
Joseph Ladu Eluzai Mogga
Page no 1107-1119 |
10.21276/sjbms.2017.2.12.9
This paper contributes to an understanding of the main factors and actors
that create the imperative for educational change in the six member countries of the
East African Community (EAC) and how governance dynamics reflect on their
policy positions. The method of study is qualitative and uses mainly existing
literature as a synthesis. The study notes that the main drivers of educational change
in the region are national and political transformation agenda; foreign aid
conditionality; the advent and revival of the East African Community; and
patronage, clientelism and corruption inherent in the neo-patrimonial set-up of the
state. The member countries of the bloc initially drew upon the imperative of nationbuilding back in the 1960s to assign value to educational change as intertwined with
Independence from colonial rule. Orthodox reform later assumed greater
prominence in the 1980s and 1990s as aid conditionality drastically undermined
gains made in educational expansion. Reforms undertaken in late 1990s and 2000s
have been in response to the quest for democratisation in East Africa. Amid the
clamour for policy convergence on educational change, there is need for a regionwide process of mutual policy borrowing, considerable harmonisation of curricula
for secondary & higher education, and increased student and staff mobility. The
study concludes that the history of state formation, political competition and statesociety relations in the EAC points to a complex variable of macro policy
convergence in educational change and governance that calls for consummate tact as
the region seeks a market-mediated identity and contemplates political federation.
ORIGINAL RESEARCH ARTICLE | Dec. 30, 2017
Assessment of in vitro Antioxidant Potential of Whole Plant of Naregamia alata W. & A.
Pious Soris Tresina, Koilpitchai Paulpriya, Vallinayagam Sornalakshmi, Veerabahu Ramasamy Mohan
Page no 349-355 |
10.21276/haya.2017.2.9.5
As a new source of natural antioxidants, there is now an expansion of
interest in phytochemicals to be used in foods and pharmaceutical preparations to
substitute synthetic antioxidants, which are being restricted due to their potential
health risks and toxicity. The present investigation deals with the in vitro antioxidant
activity of different solvent extracts of whole plant of Naregamia alata using various
antioxidants model systems viz., DPPH, Hydroxyl, superoxide and ABTS+ radical
cation scavenging activities. The ethanol extract of N. alata whole plant showed
strong superoxide radical scavenging activity. The reducing power of the extracts
were determined and compared with standard ascorbic acid. The reducing power
increased with increase in concentration. Among the solvent tested, methanol extract
of N. alata possessed strong reducing activity. The antioxidants that are present in the
whole plant of N. alata studied in this investigation could be used to inhibit or
prevent the harmful consequences of oxidative stress. The antioxidant effect could be
related to the free radical scavengers like flavonoids and phenolic compounds.
ORIGINAL RESEARCH ARTICLE | Dec. 30, 2017
Non Malignant Mature Mediastinal Teratoma: 5 Observations
Papa Salmane Ba, Souleymane Diatta, Magaye Gaye, Momar Sokhna Diop, Ndèye Fatou Sow, Papa Amath Diagne, Papa Adama Dieng, Amadou Gabriel Ciss, Assane Ndiaye, Mouhamadou Ndiaye
Page no 1316-1321 |
10.36348/sjmps.2017.v03i12.009
Mediastinal teratoma is a germinal tumor that results from embryologic disorders or germ primitive cells in the mediastinum. It’s a retrospective study concerning 5 patients addressed to our center for mediastinal tumor. Main symptoms were chest pain, dyspnea and pleural effusion syndrome. Computer tomography and chest x-rays were done for 4 patients. We found a bulky mass in left pleura, an anterior and right mediastinal Cyst, an anterior and left upper mediastinal Cyst, a bulky mass anterior in the mediastinum. In one patient, echocardiography showed a pericardial effusion with compression of cardiac chambers. Surgery was cystectomy through a posterolateral thoracotomy in many cases or a median sternotomy in one case. There was any major complication. Mediastinal teratoma have to be suspected in a tumor at the chest x-rays of a young adult. Its treatment remains complete resection of the tumor by surgery to avoid a recurrence tumor
CASE REPORT | Dec. 30, 2017
Use of Cortico-Steroid in Rheumatoid Arthritis
Dr. A.H. Ansari
Page no 356-357 |
10.21276/haya.2017.2.9.6
Rheumatoid Arthritis is an autoimmune disease which consists Joint pain,
inflammation, synovial proliferation and damage of articular cartilage. Morning
stiffness along with joints pain is a primary diagnosis. If not treated it can lead
deformity of the wrist, fingers, toes. NSAIDs are the first line treatment. Now a days
DMARDs are frequently used as soon as RA is confirmed along with some
corticosteroids. The present study reveals that use of prednisolone has a miraculous
pain relieving effect over deflazacort even for short term regime.