Obesity is highly prevalent among patients with schizophrenia, depression and bipolar disorder and is more common in persons with these conditions than in the general population. Excess weight is a major risk factor for impaired glucose tolerance, dyslipidemia, and arterial hypertension, and the clustering of obesity with these abnormalities in the metabolic syndrome correlates strongly with increased risk of coronary heart disease and premature death in all ethnic groups and regions of the world. Treatment with atypical, second-generation antipsychotics (SGAs), particularly clozapine, olanzapine, and quetiapine, are known to promote weight gain, may lead to metabolic syndrome. A descriptive, retrospective study was conducted at the mental health clinic in the Teaching Hospital Batticaloa (THB), SriLanka. Two-thirds of the population 29(63.1%) were found to be overweight 21(45.7%) and obese 8(17.4%).However, one-fourth of the population 12(26.1%) were under normal body mass index(BMI). Patients with mental illness, regardless of age or type of antipsychotic medication in use, were found to be at increased risk for many physical disturbances, including weight gain, dyslipidemia, and increased risk for coronary heart disease; and may benefit from clinical evaluation and adequate treatment, as recommended by international protocols.

Abstract: The effect of toxic chemicals on aquatic lives has been a problem in many communities and populations around the world today. Ekerekana and Okochiri communities in Okrika local government area of Rivers state Nigeria, whose river channel is a receptacle to Nigeria National Petroleum Corporation Port Harcourt Refinery’s effluent is not an exemption. It is perceived that this effluent has a negative ecological and human health impact on the affected communities. This study involved the use of Histology as a biomarker to tackle these environmental problems. The ecotoxicological study was carried out in Ekerekana (EKE station) and Okochiri (OKO station), while an aqua-culture centre – African Regional Aquaculture Centre (ARAC) at Buguma, Rivers state was used as the reference or control site. This followed a gross anatomical study of harvested fishes by applying a condition Factor (CF) equation and a fish health assessment index (HAI) protocol. Histological assessment protocol in a qualitative and semi-qualitative scenario was also done. The Environmental Water Quality Index (EWQI) result for the experimental sites were poor (10.5) and marginal (57.5) for EKE and OKO respectively. Sediment quality show elevated Pd. A comparative fish study shows: no significant difference for CF in ARAC (4.62) and OKO (6.65); HAI was better in ARAC (16.0) than OKO (55.5). This study was ecologically relevant; it revealed that Ekerekena and Okochiri creeks are contaminated with a moderate level of pollution.

In the era of digital technology, technology has developed rapidly however the information technology security lags drastically. There has been increase in risk and threats to the organization’s information. For every organization, information is a valuable asset and therefore has to be kept safe and secured. Employees are mainly responsible for security risks and threats. Organizations should give attention to the common vulnerabilities and mistakes which employees tend to make and moreover these should be addressed through awareness training programs. Information security awareness training is essential for every organization that uses technology. The study explores the importance of information security awareness training and the challenges faced by organizations is implementation of information security awareness training program. Information security training program protects the confidentiality, integrity and availability of the organization information. This study will assist management to provide effective security awareness training to technology users and enhance the safety and security of information.

Abstract: This article explains the dichotomous phenomenon of rationality with religious belief in man. Both phenomena are represented here by Moses (faith and holiness) and Spinoza (rationalism and pantheism). This very early psychological phenomenon was discussed in anthropological research by Durkheim and Claude Levi Strauss, whose conclusions are consistent with the fact that these two approaches are combined allowing the rational person to contain both opposites. After presenting the background to this phenomenon, Spinoza's pantheistic approach will be discussed. We continue with Moshe's approach to holiness based on Scripture and its interpretation, while comparing the two approaches in a comparative study close to the original texts. The discussion will lead to the limitations of reason and the need for faith to fulfill it. An explanation of this need will be presented in Durkheim and Strauss`s interpretation as a phenomenon incorporated within spirit of man as his desire to exist. The article concludes that this existential aspiration is a metaphysical phenomenon.

Salt consumption is essential but has a negative health impact when taken in excess. Therefore, this research is aimed at investigating the possible role of Moringa oleifera leave extract on lipids and antioxidant enzymes following salt loading. 24 male albino Wistar rats weighing between 180-240g were used for this study and were divided into four groups (n=6). They were given either normal rat feed and drinking water, high salt diet (8% NaCl diet) + 1% NaCl drinking water and/or Moringa oleifera extract (600 mg/kg b.w., orally, once daily). After six weeks of feeding, the animals were sacrificed and blood collected through standard method for analysis. The salt fed untreated rats had significant (p<0.05) increase in Triglycerides (TG) level, Atherogenic indices (P<0.05), Malondialdehyde (MDA), Aspartate aminotransferase (AST) and Alanine aminotransferase (ALT) (P<0.01). These parameters were significantly (p<0.05) reduced to near control values following extract treatment. Salt fed untreated rats were also observed to have significant (P<0.05) reduction in High density lipoprotein (HDL), Catalase (CAT) (P<0.01), Glutathione peroxidase (GPx) (P<0.05), Superoxide dismutase (SOD) and Albumin (ALB) (P<0.01), but the reverse was the case following extract treatment. In conclusion, consumption of Moringa oleifera leaf extract ameliorates the adverse effects of salt loading on the atherogenic, antioxidants and other indices thereby preventing possible outcome of cardiovascular disease, atherosclerosis and other related ailment. It is therefore being recommended for further research and possible use in the manufacture of drugs that are necessary in management of cardiac and other related ailments.

This text proposes an analysis of the temporalities involved in voluntary depigmentation practices. The study took place in the district "Sokoura" of Bouaké city, Côte d'Ivoire in 2016. Semi-structured individual and focus group interviews were conducted with a variety of social actors: practitioners of depigmentation, non-practitioners, former practitioners, sellers and manufacturers of lightening products, pharmacists and dermatologists. Research shows that practitioners use specific methods of application of products, depending on time. Representation of body interacts with a representation of the toxicity of lightening products, which in turn contributes to the unequal mobilization of time by the user in his "body techniques".

Melkersson Rosenthal Syndrome (SMR) is a rare orofacial granulomatosis of controversial etiology. It combines recurrent facial palsy, upper labial edema and a plicated tongue. Through a case of SMR we recall the clinical and therapeutic peculiarities of this pathology. 36-year-old patient, who presented in our consultation for labial and gingival edema of progressive worsening, evolving by outbreaks for five years. The interrogation reveals in the antecedents the notion of transient facial paralysis. Examination shows prominent lip edema in the upper lip, edema and superior gingival hypertrophy and a plicate tongue. The diagnosis of SMR was retained. Patient was put on prolonged corticosteroid treatment in degressive dose, which led to a clear clinical improvement with disappearance of the edema not recidivism after a decline of nine months. The SMR is an orofacial granulomatosis manifested by a symptomatic triad: recurrent paralysis or facial paresis, macrochelitis and a plicate tongue. This triad is rarely complete, and some minor signs can be observed. The diagnosis is mostly clinical and confirmed by histology. But a non-contributory histological analysis should not reject the diagnosis of SMR when the clinical symptomatology is obvious. Systemic corticosteroids are the most recommended treatment. It improves the quality of life and avoids or space recurrences. The prognosis remains good

This paper considers how the kotoki (political Interpreter) adopted by the Ahoms kings and later adopted by the British to deal with the various hill tribes of Arunachal Pradesh became one of the important element in the Nyishi traditional system. Here I tried to highlight the growth and development of kotoki and its mere role as a messenger to becoming a decision making body in the Nyishi Village Council. The paper focuses on the how the kotoki served as a bridge between the outsiders and Nyishi, which helps in understanding the culture, customs and traditional practices of the Nyishi. It also deals how the Nyishi after remaining isolated for so long gradually opened up to the outsiders though with much intricacy.

A simple and sensitive spectrofluorimetric method has been developed for the estimation of Gefitinib in pure and pharmaceutical dosage form. Gefitinib exhibits maximum fluorescence intensity in ethanol and Beer’s law was obeyed in the range of 1-3.5 µg/mL at an excitation wavelength (λex) of 280 nm and an emission wavelength (λem) of 512 nm. Stability studies with respect to time and temperature were also carried out. The results obtained were in good agreement with the labeled amounts of the marketed formulations. This method has been statistically evaluated and found to be accurate and precise

The erythrocyte sedimentation rate (ESR) is a nonspecific screening test to assess elevations of acute phase proteins that occur in various acute and chronic diseases. The aim of the study was to compare the ESR values by automated analyzer against the standard Westergren’s method. The comparison was done among 450 patient’s samples. In which 90 samples showed high degree of difference because of high ESR values and 180 samples showed low degree of difference because of low ESR values. The conclusion was automated ESR estimation helped a lot in measurement of ESR values in short time, but marked difference of ESR values shown in high ESR values.

Despite deviant workplace behavior has increasingly become a serious problem in today’s organizations and has been reported to significantly affect on both individual and organizational effectiveness and performance, numerous organizations have ignored and not yet prepared to cope with this problem seriously. This present study aims at enhancing the body of knowledge in the area of workplace deviance by exploring the differences between employees and employers at a selected government bank in Thailand. A sample of 143 respondents was gathered for data collection through a modified version of deviant workplace behavior questionnaire. Results of independent samples t-test analysis indicated the significant difference in employees and employers with respect to deviant workplace behavior (t = -2.005, p = .047). These results suggested that employees were less likely to demonstrate deviant workplace behavior than employers. Discussion, limitations, and recommendations for further studies were also discussed.

Learning in SMKN 5 Jambi city took place with conventional methods suspected causes of students tend to be passive in learning. For that sought the effort to change the method of learning that can make students active. The research aims to: 1) To study the procedure of developing instructional media based on adobe flash CS3 program. 2) To study adobe flash CS3 program-based learning media that is feasible to use. Research type is research and development with reference to Lee and Owens development model that is ADDIE (Analysis, Design, Develpoment, Impelementation and Evaluationi). The subjects of the study were the students of class X in SMKN 5 Jambi city totaling 22 students. Instruments used: Observation, questionnaires, evaluation of media experts, evaluation of materials experts, media evaluation by teachers of study, media evaluation by students, and pretest and posttest questions. Research findings obtained: first: the analysis phase. Student needs analysis on learning media, second: design stage, making of media design that is storyboard, third: development stage, manufacture of media product, in form of typing and revision from experts, fourth: implementation phase, product trial, fifth: evaluation phase, based on questionnaires of media experts, materials, teachers and students can be concluded that the learning media has decent criteria. Result of research that, 1) The development of instructional media based on adobe flash CS3 program on economic and business introduction subject, done systematically by fulfilling the development model of ADDIE (analysis, design, development, implementation, and evaluation). 2) Learning media based on CS3 developed adobe flash program is feasible to be used and can improve the effectiveness of student learning on economic and business introduction subjects. From result of validation test of instructional media conclude: 1) expert validation result that is validation of content or material obtained by 87% very decent category, 2) result of media expert validation obtained by 85% decent category, 3) result of teacher study field is obtained equal to 88 % category is very feasible, and 4) the results of the assessment of the students obtained by 90% very feasible category. Development of instructional media of adobe flash program is done systematic model of ADDIE and Development of learning media can improve result of learning post-test result is 73%.

In an attempt to synthesize some novel, potent antitubercular and antioxidant agents here we have reported the synthesis of a novel series of tetrahydroquinoline derivatives (III a-g). In this the titled compounds were synthesized by the reaction between substituted aromatic primary amines, N-vinylpyrrolidin-2-one and 4-nitro phthalic acid in acetonitrile. Structure of the synthesized compounds were confirmed on the basis of their physico-chemical and spectral data (IR, 1H NMR, 13C NMR and Mass). All the synthesized compounds were screened for their antitubercular and antioxidant activities using the Microplate Alamar Blue Assay (MABA) method and nitric oxide scavenging, DPPH method respectively. For antitubercular and antioxidant activities screening isoniazid and ascorbic acid were used as the standard drugs respectively. Among the synthesized compounds III a, III d and III e have shown significant anti-tubercular activity and compounds III a, III b and III e have shown significant antioxidant activity

Smartphones have turned out to be a major part of the lives of Nigerians owing to its unique capacity to combine communication and computing on mobile devices. Its evolution has made it an indispensable item in the possession of Nigerians, especially youths and elites of the older generation, as it allows for social interaction, business communication, safe storage of personal files and mobile learning among other things. Through a critical review of relevant academic studies, the article explores the evolution of smartphone in the world and how Nigerians have adopted the device. This paper argues that Nigerians adopt smartphones due to reasons such as educational needs, social communication needs, social influence and brand name and features. Some of the potentials of smartphones to the Nigerian society, as the paper posits are; knowledge sharing in work environment, improvement of social and business relationships, creation of new business dimensions and the availing of health/educational resources. Issues such as addiction, selfie syndrome, social disconnection, academic-related problems as well as health challenges were raised as the negatives from the utility of smartphones. The paper recommends that Nigerians be more disciplined with their phones when in meetings and that students should only use their smartphones to access educational materials outside the examination halls. Also, people should limit their exposure to smart phone screens to avoid visual-related problems.

The pleomorphic adenoma is a benign tumor of the salivary glands. It accounts for 45 to 65% of benign salivary gland tumors. It develops most often in the main salivary glands, especially the parotid, but it can also reach the accessory salivary glands, such as those of the palate or rarely the upper lip. We report a case of pleomorphic adenoma of the upper lip. Patient of 32 years, admitted in our formation for a painless tumefaction of the upper lip, evolving since 6 months. The clinical examination showed a subcutaneous nodule of the superior white lip, of firm consistency, mobile relative to the underlying planes, about 1 cm in diameter. Surgical excision was performed under local anesthesia with a cutaneous approach and removal of the tumor without breaking the capsule. Histological examination revealed a pleomorphic adenoma. Currently there has been no recurrence after three years of decline. The pleomorphic adenoma is a benign tumor of the salivary glands, its preferential localization is the parotid gland, rarely in the accessory salivary glands. The labial localization is very rare. It mainly affects young adult males, often asymptomatic, slow-growing, of firm consistency, well circumscribed in most cases and closer to the mucosa in relation to the skin. Our case has the particularity of being subcutaneous, which posed the differential diagnosis with a tumor of cutaneous origin. The positive diagnosis is based on surgical excision with histological examination. The potential for recurrence is very important, the excision must be complete with a margin of safety avoiding the major capsular intrusion factor risk of recurrence, and prolonged surveillance is required for the search for recurrence or malignant transformation