Sustained release formulations are becoming more popular now days for the delivery of non-steroidal anti-inflammatory drugs (NSAIDs) because of their ability to maintain therapeutic effective drug concentration for prolonged duration with low dosing frequency and side effects associated with NSAIDs. The present study was attempted to develop Sustained release tablets of a model NSAID drug, Etodolac. Etodolac Sustained release tablets were prepared by Gellan Gum (A, mg), Sodium CMC (B, mg), Xyloglucan (C, ml), Xanthan Gum (D, ml), MCC (E, ml), Talc (F, rpm), Orange flavour (G, rpm), Aspartame (H, rpm), Magnesium stearate (I, rpm). The granules were evaluated for flow properties by evaluating bulk density, tapped density, Carr’s index, Hausner’s ratio and angle of repose. The tablets were evaluated for drug polymer compatibility study by FTIR, diameter, weight variation test, hardness, friability, disintegration test, SEM, Swelling Index, In vitro drug release, release kinetics, stability studies and Plackett-Burman Experimental Design was also applied to find the optimized formulation. The FTIR study revealed that no such interactions being taking place in between drug and polymers. The flow property of granules of all tablet batches was found to be good. All the tablet formulations had good tablet physiochemical properties. The swelling of the tablets was also found optimum. From the results of in-vitro study, it was concluded that Etodolac Sustained release tablet provided most sustained release of Etodolac over extended period of time with aid of greater stability.

The purpose and objectives of this research paper was to evaluate the written test and interview exam pattern in the process of recruitment for the nonteaching position for Group B (Non-Gazetted), C and erstwhile Group D in the central and state government university/organization and also to check the impact of Implementation of written examination instead of Interview on the Non-teaching cadre in the Central Universities in India. In the above research paper we have conducted the primary research through the collection of primary data by constructing the structured questionnaire for various government employees, private employee, selfemployed, un-employed person including the students in the central and state university especially from the Banaras Hindu University. This paper will help the nonteaching staff and recruitment staff, Recruitment Rule maker who are in the process of recruitment of various post for Group B (Non-Gazetted), C and erstwhile Group D in the central and state government for the exact understanding about the true opinion of respondent who have ever faced either written examination or interview or both the pattern of examination. In this research paper we have used descriptive research design and probability sampling technique for selecting the primary data. After reviewing the various literatures we have framed the various objectives for our selected topic and on the basis of objectives we have designed the structured questionnaire for the primary data collection and formulated the Null (H0) hypothesis for conclusive oriented decision making. The sample size was 92 from the group of students, private employee, and government employee, self-employed and unemployed person. We have applied the various statistical tools such as frequency test and cross tabs (Chi square) through the IBM- SPSS 23.0 software package for data analysis and interpretation of the above case.

A survey of herbaceous fodder plants along the national highway from Parwanoo to Kaurik was carried out. Mostly along the national highway rural areas were situated and they used local flora for their cattle or livestock. Some of the herbaceous plant species used as fodder among the communities of these areas. In Present paper, 53 species belonging to 17 families and 44 genera were recorded and identified. The families with higher number of species were Poaceae with 29 species, Leguminosae with 5 species, Brassicaceae and Cyperaceae with 2 species, Acanthaceae, Begoniaceae, Caryophyllaceae, Commelinaceae, Compositae, Convolvulaceae, Cucurbitaceae, Datiscaceae, Oxalidaceae, Pedaliaceae, Polygonaceae, Solanaceae, Urticaceae with 1 species each. The genera represented by the higher number of species Setaria (3 species), Chrysopogon, Cyperus, Oplismenus, Paspalum, Saccharum, Trifolium (2 species) and rest of the genera comprising only one species.

FUO is an important medical problem worldwide, especially in the undeveloped countries like India. To have a structured, sensible and effective approach the clinician must have an understanding of the spectrum of disease and test characteristics of various diagnostic modalities available in the evaluation of FUO. The aim of this study was to analyze the clinical and etiological profile of patients having classic FUO. It was a cross sectional study for one year duration from 1st June 2013 to 31st May 2014 and was performed in the Department of Medicine in I.G.M.C. Shimla. All the admitted Patients above 18 year of age and who fulfilled the Durack and Street criteria of FUO were included in the study. After initial history taking and physical examination, the patients were subjected to routine, serological & radiographic investigations. Data was entered using microsoft excel software and analyzed with the help of epi info v7. A total of 45 patients who admitted with FUO were included Mean age of the patients was 33 years and majority of the patients were in young age group of 18-40 years (76%).There was male preponderance (69%) and most of the patients were from rural background (71%).The mean duration of fever 46.6 days and mean duration of hospitalization was 14.4 days. Infections were responsible for 80% cases of FUO. These infections included tuberculosis (29%), enteric fever (17.5%), intra-abdominal abscesses (8.8%), chloroquine responsive fever (4.4%), brucellosis (7%), lieshmaniasis (4.4%), and UTI (2.2%). Non Infectious Inflammatory Disease (NIID) and neoplasms were were responsible for only 4.4% and 2.2% of cases, while 13.2% of the cases remained undiagnosed. Infections are the most important cause of fever of unknown origin in the developing countries like India and tuberculosis is the leading cause. Thus the initial investigations should always include tests for ruling out or confirming diagnosis of infectious disease.

Bio-slurry has potential value as good quality organic fertilizer and an agent of soil carbon sequestration through build up of soil organic matter level. Cowdung and poultry manure had the higher organic carbon content as well as higher nutrient concentration compared to Cow-dung and poultry bio-slurry. Nutrient concentration particularly N, P and S in CD and CB was found lower than the PM and PB. The highest carbon mineralization in Balina soil was found in poultry manure amended soil followed by cow dung, poultry bio-slurry and the lowest in cow dung bio-slurry. Carbon mineralization of manures in Noadda soil also followed the similar trend like Balina soil. However, Carbon mineralization of poultry manure and poultry bio-slurry was lower and cow dung and cow dung bio-slurry was higher in Noadda compared to Balina soil. Thus, decomposition of manure does not depend only on the quality of soil rather both the quality of manure and soil. Decomposition of manure was found slightly higher (around 5%) in Balina soil compared to Noadda soil when averaged over four manures. Among the manure, around three to four times less amount of CO2 was evolved during the decomposition of cow-dung and poultry bio-slurry as compared to cow-dung and poultry manure. Thus, this study indicate that soil application of bio-slurry had high potential in the mitigation of the greenhouse effect as well as short-term benefits in terms of improving soil organic matter stock, as compared to manure.

The present paper described about the development and validation of three different simple, sensitive, rapid, accurate and economical UV Spectrophotometric methods. The developed methods were used for the quantitative estimation of famciclovir in bulk drug and its pharmaceutical dosage form. UV 1800 double beam UV Visible Spectrophotometer with a pair of 10mm path length matched quartz cells were used for the study. Method A (Borate buffer pH9), Method B (0.1N NaOH) Method C (Phosphate buffer pH4) and Method D (Phosphate buffer pH 7) were developed for estimation of famciclovir by zero-order and first-order derivative. Beer’s law is valid in the concentration range of 10-80 μg/mL and 10-90 μg/mL respectively and the correlation coefficient was found to be 0.999. The percentage recoveries were found to be 98-102%. The relative standard deviation was found to be <2%. LOD&LOQ were estimated. The statistical analysis proves that the methods are reproducible and selective for the routine analysis of famciclovir in bulk and its pharmaceutical dosage form

Myristica fragrans seed (Nutmeg) famed as the prominent fatty seed of medicinal and therapeutic quality came from the Spice island of Indonesia. It is endowed with phytochemicals, minerals and vitamins impart medicinal values. In captive conditions the ornamental fishes with deprived nutritional feed subjected to diseases and faded colour produces economic loss in their trade operations can be tackled by effective administration of plant products. In this perspective, a comparative study made in Poecilia latipinna (yellow molly)by providing (commercial feed) CF and TD1 (Myristica fragrans) for a duration of 60 days. The in vivo antibacterial efficacy of feed in tissues(gut & gill) of the specimen along with water samples from aquaria revealed positive result for TD1.The colour enhancing ability in yellow molly yielded best result higher for TD1 considered to CF. The total bacterial load in the water, gut as well as the gill of CF fed group was 75x104 CFU/ml, 45x104 CFU/ml& 23x104 CFU/ml while for TD1 it was 14x104 CFU/ml, 9x104 CFU/ml, 7x104CFU/ml. The quantitative estimation of carotenoids estimated was 6.32µµg/g wet weight in control and 12.12µg/g wet weight for TD1.From the present investigation arrived at the conclusion that TD1 provided better anti-bacterial activity than CF (commercial feed) not only prevent disease outbreak but also produce vibrant skin colour.

To analyze the aerobic bacteria isolated from endotracheal secretions of ventilated patients and to evaluate the antibiotic sensitivity pattern and Multi drug resistance of those isolates, present study was conducted in M.D.M. Hospital, Dr. S. N. Medical College, Jodhpur, and Rajasthan, India. Endotracheal secretions received during the study period from Jan 2016 to April 2016 were processed and all the pathogenic isolates were identified as per the standard guideline. Antibiotic sensitivity was performed for the identified pathogens according to CLSI standards. Clinical condition of the ventilated and tracheotomised patients was recorded. A total of 160 Endotracheal isolates was processed and 114(71.25) of the aspirates was showing growth. The most frequently isolated pathogens were Klebsiella sp.(37.7%), Pseudomonas(18.4%), Esch. coli(15.7) and Acinetobacter sp.(10.5%) followed by Citrobactor sp., Staph. aureus, Proteus sp.. All the organisms more or less showed both sensitive and resistance pattern but Acinetobacter sp was resistant to all the antibiotics except the antibiotic imepenem and ciprofloxacin. This study presents the most common microorganisms colonized and their antibiotic resistance pattern. The variability of flora and the potential need to adjust antibiotic coverage based on culture data suggest that surveillance tracheal aspirates are important during exacerbations

The objective of the current study was to investigate changing profile of reproduction hormone (Progesterone and Estradiol) BCS and parity in relation to the resumption of ovarian cyclicity postpartum in cows of European origin under semiarid conditions of Algeria. To measure plasma progesterone (P4) and estradiol 17-β (E2), blood samples were collected from 21 Montbéliarde dairy cows at 30, 40 and 50 d postpartum (dPP) respectively. Body condition score (BCS) was taken before and after calving. Cows were grouped based on progesterone concentration (resumption of ovarian cyclicity, ≥1 ng/mL) at 30, 40, and 50 dPP into a non ovarian activity (NOA) group (n = 6) and ovarian activity (OA) group (n = 15). P4 concentration was higher in the OA group than in the NOA group and statistically differed at 50 dPP (p = 0.04). E2 was higher in the OA group than a NOA group at d 30 (p = 0, 01) and d 40 (p = 0, 03). Despite superiority of BCS peri and postpartum but no significant differences were detected between the two groups. There was no significant difference between parity and ovarian resumption groups. Two groups were formed based on differences in onset of postpartum resumption of ovarian activity. OA (n =15/21 or 71.42 %) showed first ovulation between 30 d and 50 d after parturition. NOA (n = 6/21 or 28.57 %) manifested a first ovulation > 50 d in milk.

This study to determine the effect of career path and organizational culture on employee performance. The object of this research is employees of PT.Tri Daya Selaras This research was conducted on 58 respondents by using descriptive approach quantitative. Therefore, the data analysis used is the analysis in the form of multiple linear regression tests. The results of this study indicate that partially and simultaneously, career path variables and organizational culture affect the performance of employees of PT Tri Daya Selaras. This is evidenced from the results of partial test (t test) and the accuracy of the model also shows the significant value of two independent variables that support the hypothesis.

Nagaon district of Assam is located in the flood plains of the river Brahmaputra. The physiographic features of Nagaon District makes it ideal home for the growth of different types of economic plants. But these plants are found to be decayed by the association of some macro fungi. Among these macro fungi, different Ganoderma species were found to be associated with the different timber yielding plants and palm species. Ganoderma with great diversity produce large fruitification of different size, shape and colour. During the investigation 7 seven Ganoderma species were collected from 10 different Revenue Circles of Nagaon district. This work revealed that there are great diversity of Ganoderma species in Nagaon district, Assam. Some Ganoderma species have medicinal properties.

The intention of this study is to consider the possibility of credit card usage intention with Islamic banks‟ customers. Concept of Islamic credit card was express in edict to greet out whether these are persuading the Islamic credit card usage intention otherwise not. It means a conceptual form toward design the features essential the Islamic credit card usage intention. The significance descriptions to “concept on Islamic credit card” are widely moving the Islamic credit card usage intention as well as terminate that to have no consequence on the Islamic credit card usage intention. Although it gives the hold up for prospect researches in the outlook of Islamic credit card and it favor the advantage to the academic awareness over detaching in a superior way tumble on affecting Islamic credit card usage intention. This particular significance is toward bank executives; given them through an enhanced conception pertaining to the Malaysian bank customers‟ usage intentions for Islamic credit cards also helps them toward better plan for Islamic credit card services, in edict to bring for the financial requirements of Malaysia bank customers. The attaining a additional weighty point of view of Malaysia bank customers‟ is usage intentions for Islamic credit cards as well as determine the accurately decide the use of Islamic credit cards throughout develops the literature on Islamic credit cards.

In December of 2015, the 21st Conference of the Parties to the United Nations Framework Convention on Climate Change (UNFCC COP21) took place in Paris. UNFCC is an international environmental agreement on climate change, of which there are 195 States Parties. The U.N. Intergovernmental Panel on Climate Change (IPCC) has warned of the consequences of failing to limit global temperature rises to at least 2 degrees Celsius (above pre-industrial times), highlighting that the impacts would pose a threat to humanity and could lead to irreversible climate change. The meeting in Paris was hailed as a make-or-break opportunity to secure an international agreement on approaches to tacking climate change, a commitment to a longer-term goal of near zero net emissions in the second half of the 21st century, and supporting a transition to a clean economy and low carbon society. This paper discusses the issues and solutions of climate change, development and critical views, the UAE environmental regulation, company's environmental responsibility, and the future of the Paris Convention on Climate Change.

This study aims to determine the effect of transformational leadership and work environment on Employee’s performance. The object of this study was employees of PT Pegadaian branches Meruya West Jakarta. The population in this study was 40 employees. The results of this research used saturated sampling technique. Data collecting used questionnaires and subsequent, then data analyzed using multiple linear regressions. Data processing for statistical tests performed with SPSS 21. The results showed that both independent variables of transformational leadership and significant positive effect on Employee’s performance, while for the working environment variable was not significant or positive effect on Employee’s performance.

This study examined the watering regime that will enhance best germination and early seedling growth of Tetrapleura tetraptera. Seeds and seedlings of the plant were subjected to five different watering regimes viz: watering once weekly with 50ml, watering twice weekly with 50ml, watering once weekly with 100ml, watering twice weekly with 100ml and watering with 100ml only on the day of planting (as control for the seeds experiment), no watering (as control for the seedling experiments). The results of the experiment showed that watering once weekly with 100ml was the most effective watering regime for enhancing seed germination. This resulted in 85% germination, followed by the seeds watered twice weekly with 50ml (65%) and watering twice weekly with 100ml (50%). Other watering regimes were less or not effective. While watering twice weekly with 100ml was the most effective watering regime for enhancing seedling growth in this plant. This resulted in significantly highest plant height, number of leaves and broadest leaf area (22.00 cm, 15.00 and 27.51cm2 respectively) at the third month of planting. It also resulted in highest seedling stem girth (3.50 cm) though this was not significantly different from seedling treated with other watering regimes except for seedling treated with no watering which gave 0.20 cm. The results of these studies demonstrated that water supply may be a limitation for raising Tetrapleura tetraptera in the nursery as the soil moisture influenced germinability and early growth of this plant.