Focal dermal hypoplasia (FDH) or Goltz syndrome is a rare genetic skin disorder; characterized by abnormalities of both ectodermal and mesodermal structures. We report the case of a girl of 8 years of Moroccan origin, second of a fratery of two, resulting from a non-consanguineous marriage and without any particular family history. Examination at admission notes that the patient presents with an overall hypotrophy, right facial asymmetry with low-set protruding ear, narrow nasal bridge. The examination of the oral cavity notes: Arborescent papillomas of the oral mucosa, hypertrophy gingival, abnormous tooth form, ectopic extensive dental caries eruption. Skeletal abnormalities: Ectrodactyly ("lobsterclaw" hand deformity) of the right hand, Syndactyly bilateral second and third toes. Hypopigmentation of the abdomen skin, microphthalmia of the right eye. The rest of the clinical examination is without particularity. The genetic study confirmed the diagnosis of FDH by highlighting a mutation of the PORCN gene.

Since Decision of the Constitutional Court Number 137 / PUU-XIII / 2015 and Number 56 / PUU-XIV / 2016, the Minister of Home Affairs and the Governor is not authorized to cancel the Local Regulation. Both Constitutional Court Decisions can not be denied to be one of the obstacles for the central government to suppress the growth rate of overlapping local regulations, so that necessary steps to disbursing obesity of local regulations starting from the upstream or since the planning stage. One of the steps that can be taken to obstruct obesity rate of Local Regulation is by conducting harmonization activities at planning stage that is harmonization to draft Program of Formation of Local Regulation.

The accurate morphological identification of the cells is a diagnostic problem in conventional smears. By using 10% alcohol formalin as a fixative and obtaining cell block gives effective diagnosis regarding cellular morphology in serous effusions. This study was carried out to evaluate cell block technique as a diagnostic tool for serous effusions. It is expected that cell block technique will give better morphological details and thereby improve the sensitivity of the diagnosis in comparison with conventional smears. This retrospective study was conducted in cytology section in a tertiary care hospital,46 fluid samples were subjected to diagnostic evaluation over a period of 10months.The cell blocks were prepared by using 10% alcohol-formalin as a fixing agent along with the conventional smears. The nucleo-cytoplasmic details were evaluated as benign, suspicious for malignancy and malignancy in both conventional smears and cell block method. Out of 46cases only 3/46cases (6.53%) found to be malignant in conventional smearsand using cell block technique 6/46cases (13.043%) were positive for malignancy. Cell block technique is a useful adjuvant evaluating fluid cytology for the more presumptive diagnosis, when combined with conventional smear method. Cell blocks can be stored for a longer period for further evaluation and can be used for special stains, Immunohistochemistry and molecular diagnosis in order to obtain specific diagnosis.

There has already been the ongoing trend in the shift of focus in specialized translator training from domain-specific knowledge training to an all-round competence development. Based on the analysis of the current problem with the specialized translator training with subject knowledge, this study is to propose suggestions as to how translators deal with the problem of lacking in subject knowledge. Provided in this paper is the detailed illustrations of four methods of selfenriched translator training with specialized subject knowledge, i.e. self-training in efficient subject knowledge management, self-training for efficient reading, selftraining to reuse translations in parallel corpus, self-training to use post-editing machine translations. This study aims to contribute to the future specialized translator training by serving as a reference source or even an inclusion as component parts in these training programs.

Repetitive behavior is a common symptom in children and is characterised by sameness, rigidity and repetitiveness. These stereotypic and repetitive behaviors are seen in various psychiatric as well as neurological disorders. Till today, the focus of almost all studies was on repetitive behavior in ASD & OCD. The purpose of this study is to bring all the children presenting with repetitive behavior under the same roof, to investigate the patterns of repetitive behaviour in children associated with different childhood disorders and to study the distribution and severity of repetitive behaviors among childhood psychiatric disorders. A Cross-sectional observational study, for the duration of 1 year, was performed on 72 Children (0-12yr) with repetitive behaviour attending the child guidance clinic, who had given consent. Children were screened by using CBCL and diagnosed as per ICD-10 DCR. Severity of repetitive behaviors was assessed using the RBS-R scale & score of different subscale of each disorder were compared. Statistical analysis was done on SPSS version 23. Total 8 types of disorders were included in this study. Stereotyped behavior, Self-injurious behavior more in PDD than OCD, MR &TIC. Compulsive behavior more in OCD than PDD, TIC & MR. Ritualistic behavior, sameness behavior, restricted behavior and total score are more in OCD than tic disorder. Stereotyped behavior more in Tic disorder than OCD. Stereotyped behavior and self-injurious behavior more in MR than OCD. This research contributes to the literature looking at domains or specific groups of repetitive behavior within children with PDD, OCD, TIC and other disorders. As per our knowledge this is the first study in India on repetitive behavior in different childhood disorders.

Determining sex plays important role in the identification of the unknown person. The positive identification of human remains requires the matching of physical characteristics of the deceased with records of the physical characteristics made before death. Several methods may be used to produce identification with an aggregate high level of reliability. Sex determination is usually done by osteometry, DNA analysis and even by odontometric parameters. Aim of the study was to identify gender using measurements of mesiodistal crown width of the six maxillary anterior teeth (later added to derive combined mesiodistal widths), fronto-occipital head circumference, height, and diameter of the skull on a lateral cephalography. In this study, 100 persons were evaluated. After obtaining informed consent from the subject selected, measurements of mesiodistal crown width of the six maxillary anterior teeth (later added to derive combined mesiodistal widths), fronto-occipital head circumference, height, and diameter of the skull on a lateral cephalography were performed. Combined data, male, and female data were analyzed separately for binary logistical analysis for sex determination to the parameters recorded and discriminant function equation were derived for each parameter. In the present study mean values of all the parameters were calculated and showed a statistically significant variation between males and females. Discriminant function analysis was performed for all the variables which correctly classified 91% of the cases. Our Study suggests that the discriminant functional analysis has proved that the sex of unknown sex skull can be determined using above mentioned parameters. Studies at a large scale are in need to approve or disprove the above factor.

Telehealth is increasingly used to manage many long-term conditions including ones which affect physical and mental health. The range of methods of delivering telehealth is increasing as technology, and the internet, develop and become increasingly ubiquitous. The various means of delivering telehealth includes the use of computers, smart phones, mobile phones and landlines. As the means of communicating remotely increase, so do the range of ways in which telehealth can be used to both monitor long-term conditions and aid in the delivery of self-care. This paper reviews various applications of telehealth as they are applied to the management of type II diabetes. It examines the role of the different forms of technology in monitoring the disease remotely, in prompting episodes of self-care and in the delivery of proactive education. The review identifies sixteen randomised controlled trials which all use telehealth, in at least one of its forms, to deliver monitoring, disease management prompts and proactive education (or any combination of the three) remotely. The quality of the evidence uncovered is variable, with the long-term utility of many of the approaches remaining largely unproven because of the time limited nature of the research available. The least equivocal findings are from the studies which take a three pronged approach to the delivery of telehealth – monitoring, prompting and educating – which all showed measurable benefit in terms of the management of blood glucose levels. This improvement also held true for the studies which employed both monitoring and real time disease management prompts alone. The evidence suggests therefore, that attempts to use telehealth to improve the management of type II need to include, at the very least, an element of remote monitoring and real-time disease management prompts. Whether the benefits which accrue from these approaches have any long-term value needs to be further researched.

This study aims to determine the improvement Skills Process of Science after developing science-learning media about human waste-based digestive systems. The research was conducted at SDN Kapuk 02. This research used R & D research method which refers to Dick and Carey model. Respondents in this study consisted of expert test (media, language, and material), one to one, testtrial small group, andtest fieldtest. The results of the development of Torso Digestive System Human assessed by media experts ie 88.3%, material experts 90%, and linguists 93.3%. The next stage of Human Digestive System Media performedtrial one to one with 89% product feasibility, trial small group with 90.1% product feasibility, and field test with 90.4% feasibility. Assessment made into the category is very good. PPP in this research was conducted by classroom teachers. Classroom teachers conduct assessments before and after media use. At the time before using the Human Digestive System media, the student's KPS earned an average of 68.7%, after using Human digestive System media has increased to 89.5%. This indicates that the Human digestive system media improves student's KPS until it reaches the completeness criteria. Thus the media of Human Digestive System has effectiveness to the student's KPS.

This study was designed to compare the properties, kinetics and stability of the immobilized lettuce protease with the free one. We also aimed to test the use of the immobilized lettuce protease for the production of novel bile binding and tyrosinase-inhibitory peptides from plant food processing wastes (cauliflower midrib and broad bean leaves). Immobilized lettuce protease was prepared previously from Lactuca sativa (lettuce) seeds. Free lettuce protease was immobilized on alginate-glutraldehyde beads by covalent bond at optimum conditions with high immobilization efficiency. In the present study, immobilized protease showed optimal activity 221.5 U/mg enzyme protein at pH 10 and 70°C, while the free one showed 22 U/mg enzyme protein at pH 7 and 60°C. Km values of the immobilized and free protease toward azocasein were 1.143 and 1.442 mg, and Vmax values were 142.9 and 24.6 U/mg enzyme protein, respectively. Immobilization of lettuce protease resulted in an increase of activation energy (Ea) for azocasein hydrolysis from 9.6 to 23 Kj/mol. Immobilization improved its turnover number Kcat (15.96 Kj/mol) and catalytic efficiency Kcat /Km (13.96 Kj/mol) compared to that of the free one (3.09 and 2.143 Kj/mol, respectively). Deactivation energy (Ed) values were 38.76 and 55.41 for the free and immobilized protease, respectively, confirming the enzyme stability by immobilization. Free protease could be stored for 70 days at 4°C with loss of only 20% of its initial activity, while the immobilized one could be stored for 23 and 46 days with retention of 114 and 74.5% of its initial activity at 9°C, respectively. CaCl2 increased the rigidity, stability and activity of the immobilized enzyme by 125%. Cauliflower peptides were enzymatically prepared from cauliflower protein. It had higher bile binding and tyrosinase inhibitor potency than the parent protein. Immobilized lettuce protease and cauliflower peptides could be applied in food and pharmaceutical industries.

Abstract: The present study was undertaken to measure the aggression and self esteem of volleyball players of J&k State. For the study the population was all the volleyball players of Jammu and Kashmir State. For the present study, 80 volleyball players were selected randomly from Govt. degree colleges of different districts of Jammu & Kashmir. All subjects were selected with the help of purposive sampling technique .Only male sports men were selected. This was a survey study under Descriptive research. For the collection of data the researcher administered the Buss and Warren aggression Scale and Dr. Morris Rosenberg self esteem scale. The questionnaires filled up by the subjects were collected and analyzed by using the SPSS Software version 17.00. After data collection, data of aggression and self esteem of volleyball players was compared by using t-test and the result was analyzed and interpretations were drawn.

A holistic study of tinnitus to explore the etiology of tinnitus and to examine a successful alternative self-help approach, which combines the human voice (toning) with energy alignment. Four case studies of adults who suffered from tinnitus are used to illustrate the benefits of approach. Each adult sustained a three - week self-help programme of toning, colour and energetic alignment. The clinician researcher evaluates the methodology of the approach and cause of symptoms from a physiological and metaphysical perspective.

This research aims to know the influence of the application of mathematical approach is realistic and critical thinking towards problem-solving ability of grade V primary school in Tangerang. This type of research is to experiment with the use of the technique of simple random sampling has been done to 60 students. Retrieval of data obtained through tests and analyzed using the variant analysis (ANAVA) two lanes with a design treatment by level 2 x 2.Research results showed: (1) problem solving Ability among students who are taught using realistic mathematical approach higher than students taught using conventional methods, (2) there is the influence of the interaction between the application realistic mathematical approach to critical thinking and problem-solving abilities, against (3) problem solving Ability among students who are taught using realistic mathematical approach higher than students taught using methods the conventional group of students who have a high, critical thinking and (4) problem solving Ability among students who are taught using conventional methods is higher than students taught using a mathematical approach is realistic on a group of students with critical thinking.The results of this research show that the mathematical approach with a realistic critical thinking was able to increase the ability of solving math problems.

Abstract: The promulgation of the Belt and Road Initiative brings to fore the shift in world economic power to the east. The relations between members of Initiative and the changes of their positions will determine the long-term success or otherwise of this Initiative. The paper adopts social network analysis to set up the network relation between member countries, studies the network structure and its evolution trends, and identifies the position and role of members in the Initiative with data from bilateral investments for the period 2005 to 2015. We conclude that the network structure of Belt, Road Initiative’s broad purpose of ensuring a greater level of economic integration between and among countries on the Belt, Road corridor with regards to bilateral investments is gradually being achieved although at a slower pace than may have been expected by framers of the Initiative with less influence being exerted by China. The beneficial economic integration will be very much enhanced with China in the core position.

This research is about meninkatkan ability of student in mastery of Indonesian student vocabulary by using picture and picture method. The purpose of this research is to improve students' vocabulary mastery through picture and picture method. This research method is action research consisting of two cycles. The subjects of this study were the 3rd graders of elementary school, which amounted to 25 students. In completing this study, the authors of observation methods, written tests and field notes, as a means of collecting data collection. By conducting this action research, it was found that using the picture and picture method can improve students 'ability in mastery of students' vocabulary in each cycle. The results can be seen from the improvement processes in improving students' vocabulary mastery in each cycle. The first cycle found the mean completion criteria and the second cycle found an average value of 95.7 which means above the completeness criteria minimal, so the use of picture and picture method can help students in improving students' vocabulary mastery.

Abstract: This dissertation examines the way Arabs are stereotyped in Hollywood war films. The dissertation shows how the enemy is portrayed in Hollywood war films. After World War II Nazis were the enemy in Hollywood combat films, and most of the films about WWII, depict Nazis as such. After WWII, the role of the enemy shifted from the Nazis to the Vietnamese. The fear of communism and the victory after the Cold War led Hollywood to depict Vietnamese as enemy in Vietnam War combat films. To study the way the Arabs are stereotyped in Hollywood war films, this dissertation makes a comparison between the depiction of these historical enemies and the representation of Iraqis in war films. By analysing motion pictures produced by Hollywood following each war, similarities and differences are identified in the way enemies are portrayed.