ORIGINAL RESEARCH ARTICLE | April 30, 2018
Prevalence of Typhoid Fever in Pediatric Patients of Adilabad
K. Ananth Rao, Mohd Inayatulla Khan, Sridhar Yadav
Page no 186-190 |
10.36348/sjm.2018.v03i04.016
Enteric fevers are a common occurrence in pediatric patients especially in rural and tribal areas where the conditions of sanitation are generally poor. The common causative organisms are gram-negative bacteria Salmonella Typhi and Salmonella Paratyphi A. There is a limited data regarding the burden of the disease in Tribal Adilabad region. With this background, we in the present study tried to evaluate the prevalence of enteric fever in pediatric patients with RIMS Adilabad. Method: The data were collected from the Department of Pediatrics, Rajiv Gandhi Institute of Medical Sciences [RIMS], Adilabad from August-October 2017. All the febrile patients attending the pediatric OPD, Rajiv Gandhi Institute of Media [RIMS] presenting with clinical signs and symptoms of typhoid fever and the fever were lasting for more than 3 days. They were not on antibiotic therapy. A total of [n=66] 34 male and 32 female patients aged 0-14 years were found to have positive cultures for S.typhi. Patients were treated with ceftriaxone IV dosage based on the 100 mg/kg IV 24h for 10-14 days Results: the Most important symptom of typhoid is fever which was seen in all the 66 (100%) of cases involved in the study. The next common symptom was headache in 37 (56.06%) of cases followed by hypotension 22 (33.33%), diarrhea 21(31.81%), Abdominal pain 19 (28.79%), constipation 18 (27.27%), vomiting 14 (21.21 %) and only 7 (10.60%) and 6 (9.0 %) presented with cough and bradycardia. Maximum 45.45% patients get rid of typhoid fever after one week of medication. 22.73% of patients get rid of typhoid fever in two weeks of medication. 9.0% were cleared of infection after 3 weeks of medication. Conclusion: Typhoid fever is common in this group of the population especially in children. Fever, diarrhea and abdominal pain were the major clinical symptoms. No multi-drug resistant S.typhi was found in this population. Increase awareness regarding hygiene maintenance, sanitation and vaccinations in the population is required to reduce the burden of the disease in this area
ORIGINAL RESEARCH ARTICLE | April 30, 2018
Xanthogranulomatous Appendicitis: an Unusual Pattern of Appendiceal Inflammation
Rana Shaker AL-Zaidi
Page no 115-120 |
10.21276/sjpm.2018.3.4.4
Xanthogranulomatous inflammation is an unusual destructive chronic
inflammatory process that involves various organs & tissues particularly gallbladder
(xanthogranulomatous cholecystitis) & kidney (xanthogranulomatous pyelonephritis).
Xanthogranulomatous appendicitis (XA) is a rare form of appendiceal inflammation
that has been regarded as an unusual healing pattern of appendicitis associated with
delayed or interval appendectomy. It poses a significant diagnostic challenge because it
can mimic clinically, radiologically, & even pathologically malignant tumors as well as
other inflammatory processes of appendix. Little information has been written in the
literature regarding this entity. In this review article, data have been collected from all
the previously reported cases in the literature including my observation in a XA case I
have diagnosed.
ORIGINAL RESEARCH ARTICLE | April 30, 2018
Research Lifescape: social economy in the village of Tanjung Jabung Timur and Muaro Jambi Districts in Jambi Province
Dr. Muhammad Safri
Page no 385-393 |
10.21276/sjbms.2018.3.4.3
There are 10 (ten) intervention villages studied, there are 4 villages located
in Muaro Jambi regency such as Rondang Village, Londrang, Rukan and Desa Manis
Mato. While 6 (six) villages studied and located in Tanjung Jabung Timur Regency
include: Parit Culum Village, Koto Kandis Dendang, Rahayu Catur, Jati Mulyo, Rawa
Sari and Dawam Bay Village. The aim of study is to determine the condition of rural
land around Londrang peatland, the socioeconomic condition of local villagers, the
value income of the villagers associated with the Food and Non Food Poverty Line,
and the value of the Community Contingent on the basis of willingness to pay/WTP
and willingness to accept/WTA.The data of research were obtained from secondary
data collection, followed by primary data collection, visiting villagers to conduct
interviews packaged in group discussion activities and direct observation of the
socioeconomic phenomena of the villagers.Based on the results of research, it is found
that generally have the same livelihood from the agricultural sector. They are still in
the primary sector and have not moved in the secondary stage in the form of
agricultural processing activities. The economic condition of the villagers in the
villages of Tanjung Jabung Regency Timur is relatively better than the economic
condition of the villagers in Muaro Jambi Regency. The villagers researched and
located in Tanjung Timur Regency are generally transmigration residents, at the same
time villagers residing in Muaro Jambi District are local indigenous people with the
condition of natural carrying capacity or land between 2 (two) areas in regency also
different physical condition. Almost all of the studied villages above the poverty line
according to BPS criteria, except for 1 village that is Manis Mato village in Muaro
Jambi Regency is still below the poverty line. On average, all villagers still want the
value of environmental sustainability, if measured is still from the high value of
willingness to accept/WTA compared to willingness to pay/WTP.
ORIGINAL RESEARCH ARTICLE | April 30, 2018
Correlation Analysis of Immunological Status and Clinical Parameters with Their Histological Subtype during the Treatment of Leprosy Patients
Vallamreddy Siva Kota Reddy, Vaheda Begam Korrapadu
Page no 99-104 |
10.21276/sjpm.2018.3.4.1
Leprosy is a skin disease affecting also the nerves was caused by
Mycobacterium leprae. Multidrug therapy (MDT) cures the infection, but
immunological reactions may occur and neuropathy may lead to disability and
deformity. The current study aimed to understand the immune status of the patient
before and after treatment by correlating histological subtype and peripheral blood
lymphocyte count. Total number of 35 cases was studied. Blood samples were taken
from the patients and complete blood picture was done before instituting the MDT
including TLC and DLC. After 6 months of treatment, patients were followed up with
complete blood picture. In lepromatous leprosy group (BL+LL) total mean WBC
count was increased with 11,414 (range 7,000- 22,600 mm3) above the range of
normal limits before treatment. It was in the mean normal range after treatment with
8514 (range 5,900- 11,000mm3). Lymphocyte count has increased after treatment.
After the treatment, there is considerable increase in lymphocyte count. It was in the
range of 34% to 42% with a mean value of 38.1%.
ORIGINAL RESEARCH ARTICLE | April 30, 2018
Study of Family Environmental Status of Children and Adolescents Suffering From Attention Deficit Hyperactivity Disorder with Comorbid Disruptive Behaviour Disorder
Chandana Debnath, Saswati Nath, Dipak Kumar Patra, Sourav Kundu, Niladri Banerjee
Page no 406-413 |
10.36348/sjmps.2018.v04i04.006
Attention Deficit Hyperactivity Disorder (ADHD) is a common neuro developmental disorder in children. Most common comorbidity is Disruptive behaviour disorder. Family and social environmental factors are not considered as having etiological role but may exacerbate pre-existing symptoms and genetic or neurological vulnerability. These children are particularly challenging and require intensive intervention to prevent greater morbidity and impairment. This study aims to see whether family adversity is related to ADHD with Conduct disorder. This case –control, cross sectional study was done in a child Guidance clinic of Psychiatry department of R.G Kar Medical College, Kolkata. Children diagnosed as ADHD with co morbid DBD fulfilling the inclusion and exclusion criteria were selected as cases (N=32). Control population was collected from schools of both rural and urban areas who did not have any psychiatric disorder (N =62). The consenting parents of the cases and control were interviewed with a standardized questionnaire named Family Environmental scale (F.E.S). Significant differences were found in all variables. The control group family has shown more cohesion, more acceptance and caring, more expressiveness, more independence, more family organisation and control, enjoyed more active recreational orientation but less family conflict. The cases, ADHD with co morbid ODD or CD have shown high family conflict.
ORIGINAL RESEARCH ARTICLE | April 30, 2018
Retrospective Study of Cholecystectomy Specimens
Dr. Gayathri Devi Thanigaimani, Dr. Hemalatha Ganapathy
Page no 105-108 |
10.21276/sjpm.2018.3.4.2
Surgical resection of gall bladder is a common surgery and the most
common indication for it, is inflammation. Incidental diagnosis of malignancy in such
specimens changes the entire perspective of future management for the patient as gall
bladder carcinoma is a malignancy with poor prognosis and high fatality. The aim of
the study is to study the clinicopathological to study the clinic pathological correlation
of the cholecystectomy specimens received in our pathology laboratory. This was a
retrospective study over a period of 2 years from June 2015 to May 2017. The case
reports were reviewed and data collected. The age and sex incidence, the presenting
complaint with duration, the investigations done, the clinical diagnosis and
histological diagnosis were analysed. A total of 200 cases of gall bladder were
received in the lab during the study period. About 65% were women and the age
group commonly involved was 40 to 60yrs. The most common presenting symptom
was right upper quadrant pain. The clinical diagnosis correlated with the
histopathological diagnosis in 99% of patients while it was different in two cases
(1%). Both the cases were adenocarcinoma of gall bladder diagnosed incidentally
during histopathological examination. Though the two patients had had CT done
preoperatively, gall bladder malignancy was diagnosed histopathologically only. This
stresses the importance of meticulous examination of gall bladder specimens and the
importance of examining the surgically resected margins of the gall bladders.
ORIGINAL RESEARCH ARTICLE | April 30, 2018
The Impact of Fasting During the Month of Ramadan on Renal Function of Patients with Chronic Renal Failure: A Retrospective Study of 47 Patients
Hassani Mohamed
Page no 436-438 |
10.36348/sjmps.2018.v04i04.009
Fasting during the month of Ramadan is one of the five pillars of Islam. During this month, adult Muslims are obligated to refrain from eating and drinking from dawn to dusk. Some of our CKF patients fast the whole month against medical advice, for many raisons (religious or social customs). The aim of our study is to evaluate the impact of fasting on the renal function in this population. We conducted retrospective study of 47 patients (16 females, mean age 61.9 years; 15-85 years) with a eGFR less than 90 ml/min/1.73m2, most had a eGFR less than 60 ml/min/1.73m2. For patients with chronic kidney disease, the existing data in the literature are scarce and give inconclusive results. Patients should be monitored closely by their physicians while fasting. If a sign or symptom of acute tubular necrosis occurred, the fasting should be discontinued
ORIGINAL RESEARCH ARTICLE | April 30, 2018
Modeling of the Forming Process for Aluminum Detail
Vyacheslav Lyashenko, Rami Matarneh, Svitlana Sotnik, Nataliya Belova
Page no 219-227 |
10.21276/sjeat.2018.3.4.3
In the work, modeling of the forming process for aluminum detail was
carried out. As a detail, "Pen" is chosen for which the material AK6M2 is determined,
taking into account its physico-chemical properties. In the beginning, a 3D detail
model is constructed, using the SolidWorks program. Then in the program Nova
Flow, entire process of filling the mold in real time, rate of filling the mold cavity
with metal, hardening time of the casting was determined. The temperature change
dynamics of the casting after filling the mold is investigated. Possible nodes are
susceptible to formation of shrinkage shells.
REVIEW ARTICLE | April 30, 2018
Therapeutic Potential of Herbal Ethosome in Applied Nanotechnology
Banjir Sultana, Prakash Rajak, Biman Bhuyan, Evana Patra, Angkita Baruah, Dipankar Paul
Page no 443-454 |
10.36348/sjmps.2018.v04i04.011
Phytomedicines are becoming more popular in the world for their ability to cure diseases with less toxicity and better therapeutic efficacy. Herbal medicines may also have disadvantages of poor bioavailability, toxicity, stability issues and patient compliance. In order to minimize these problems various drug delivery systems such as liposomes, phytosomes, niosomes, ethosomes and trasferosomes etc are being developed for phytomedicines. Novel drug delivery systems can improve bioavailability of drug that refers to the existence of drugs in the body part where they are actually needed. Ethosomes are noninvasive flexible vesicular carriers that enable the drugs to permeate through the deeper layers of skin and systemic circulation. They are mainly composed of phospholipids, high concentration of ethanol and water. As ethanol is known for its disturbance of skin lipid bilayer arrangement; therefore, inclusion of ethanol into a vesicular membrane provides the ability of vesicle to permeate through the stratum corneum. The high flexibility of ethosomal carrier from the added ethanol allows the elastic carrier to squeeze through the skin pores. Herbal ethosomal formulation has been effectively used to enhance bioavailability of many herbs including Glycyrrhiza glabra, Sophora alopercuroides, Cannabis sativa, Sesbania grandiflora and Podophyllum hexandrum
ORIGINAL RESEARCH ARTICLE | April 30, 2018
Improvement of the Health Status of Sheep by the Use of Medicinal Plants and Their Effects on Oxidative Stress Parameters
Nedjmeddine Soltani, Saliha Dahamna, Rachid Rouabhi, Salim Gasmi
Page no 365-372 |
10.21276/haya.2018.3.4.4
Medicinal plants are used for their beneficial properties to the health of
animals. Recently, it has been found that the use of medicinal plants eliminates
industrial pollutants. The objective of our work is to determine and evaluate the effect
of two medicinal plants (Thymus algeriensis and Artemisia campestris) on oxidative
stress parameters in sheep. The results obtained in liver cells show that medicinal
plants have produced a globally antioxidant preventive effect, this is revealed by the
significant decrease in the GSH level (199.976±1.913), and the enzymatic activity of
CAT (0.699±0.02). In addition, an increase in the enzymatic activities of GST
(0.435±0.017), GPx (1.881±0.040) and MDA (29.009±0.086) was observed. These
results clearly show an antioxidant effect of medicinal plants on the organism of
sheep.
CASE REPORT | April 30, 2018
Acute Interstitial Nephritis Associated Multiple Myeloma: A Case Report
Hassani Mohamed, El Akramine Maroua
Page no 439-442 |
10.36348/sjmps.2018.v04i04.010
Patients with multiple myeloma may present a variety of renal manifestations as a result of damage from circulating light chain immunoglobulin components. The renal alterations can interest any of the renal compartments, and in certain cases more than one compartment can be affected. The resulting high serum concentrations of these proteins often lead to tubular interstitial injuries as endocytic receptors in the proximal tubules are overwhelmed. A 46-year-old white man with a history of left hip pain was diagnosed as multiple myeloma. Imaging including MRI and PET scan showed a left pelvic heterogenous mass causing bone destruction and compressing the adjacent organs. He was referred to the nephrology department due to the onset of acute kidney injury requiring hemodialysis. A kidney biopsy was performed and showed patterns of acute interstitial nephritis and focal linear staining for kappa light chains along tubular basement membranes on immunofluorescence. After glucocorticoids for acute interstitial nephritis and chemotherapy (Bortezomib -Cyclophosphamide - Dexamethasone) directed against the clone, the renal function partially improved and the patient got off hemodialysis support. Conclusion: Acute kidney injury may be the first clinical presentation in patients with multiple myeloma. Could interstitial nephritis be the only manifestation of MM without myeloma cast nephropathy and whether it was glucocorticoid or chemotherapy directed against the clone that has resulted in a significant improvement in renal function.
ORIGINAL RESEARCH ARTICLE | April 30, 2018
A Qualitative Study on the Phytochemical Profiling of Bacopa monnieri with Organic Solvents
Divya MS, Dr. Sreeja J
Page no 381-383 |
10.21276/haya.2018.3.4.6
Bacopa monnieri or Brahmi(family- Scrophulariaceae) used in indigenous
medicine as nerve tonic and cardio tonic possess diuretic, adaptogenic, antioxidant,
antidepressant, antibacterial properties, enhances cognition profoundly flourishes in
the marshy regions. Preliminary phytochemical tests carried out using aqueous,
ethanol and methanol extracts revealed the presence of phytochemicals like amino
acids, alkaloids, carbohydrates, glycosides, flavonoids, phenol, saponins and tannin
accounted for its medicinal aspects in organic solvents.
ORIGINAL RESEARCH ARTICLE | April 30, 2018
Institutional Support for Entrepreneurship Development: A Scenario of SMEs in KSA
Dr. Hassan K Al Mahdi
Page no 477-489 |
10.21276/sjbms.2018.3.4.14
SMEs are recognized as a most effective mechanism to push economic and
social development. Their role becomes more important in Saudi economy which is in
the diversification stage in an attempt to reduce KSA dependence on oil and to realize
the Vision 2030. The government has established various institutions and working
along with private sector to offer SMEs financial, technical and training support aimed
at development of entrepreneurship. In this paper an attempt has been made to
examine the status of SMEs and to identify & study the activities of the institutions
extending financial and non-financial support to SMEs. The researcher has examined
thirteen main institutions which are playing an important role in providing support in
the areas of technology, marketing, financing, training, incubators, consultancy and
policy & incentives. Finally suggestions have been extended for further improvement
in order to capitalize the opportunities resulting in development and growth of
entrepreneurship.
ORIGINAL RESEARCH ARTICLE | April 30, 2018
Phytochemical Studies on Ipomoea sepiaria Roxb
Prasanth B, N.A Aleykutty, Jyoti Harindran
Page no 339-349 |
10.21276/haya.2018.3.4.1
Ipomoea sepiaria Roxb., also known as Purple heart glory is a slender vine
belonging to family Convolvulaceae. In Sanskrit it is known as lakshmana, in hindi as
Bankalmi and in Malayalam as Tirutali. It is one among the ten sacred plants known
collectively as “Dasapushpam” in Kerala. These plants are used for rejuvenating the
body in the form of „karkidakakanji‟ in the monsoon season in Kerala which is also
prescribed in text books of ayurveda. Juice of the plant is used as deobstruent,
diuretic, hypotensive, uterine tonic and antidote to arsenic poisoning. The present
study aims at the preliminary phytochemical screening of the successive solvent
extracts of Ipomoea sepiaria Roxb. and identification of compounds in the Hexane
extract by Gas Chromatography- Mass Spectrometry technique. The preliminary
phytochemical screening revealed the presence flavanoids, tannins, flavanoids,
terpenoids, steroids, sterols, cardiac glycosides and carbohydrates. The GC-MS
analysis revealed the presence of the compounds Caryophyllene, α –Curcumene, β –
Cadinene, ϒ –Elemene, Caryophyllene oxide, Asarone, Germacrone, Methyl
isopimarate, Abietic acid, Lupeol, β –Amyrin and α –Amyrin which have not been so
far reported in Ipomoea sepiaria. The higher percentages of compounds α-
amyrin(33.341) β –Amyrin(16.28) which form the basic skeleton of triterpenoid
saponins are promising.
ORIGINAL RESEARCH ARTICLE | April 30, 2018
Oxidative Stress in Iron Deficiency Anemia
Ravjit Kaur Sabharwal, Supriya Rana, Indira R. Samal, Pinak Samal
Page no 377-381 |
10.36348/sjmps.2018.v04i04.001
Iron deficiency anemia is widely prevalent nutritional disorder worldwide, resulting in oxidative stress which in turn leads to cardiovascular diseases, cancer, diabetes mellitus and ageing. Oxidative stress and iron levels were studied in 84 subjects, 36 of whom were anemic (Hb <11 gm/dl) and 48 healthy subjects who were taken as controls. In these subjects serum iron, Total Antioxidant Capacity, superoxide dismutase and malondialdehyde levels were estimated. In the present study it was found that anemic subjects had higher oxidative stress as compared to controls and female anemia subjects were more affected than males. Preventive action may help in reducing the morbidities caused by the oxidative stress