Introduction: The gender-based violence (GBV) is the set of abuses, means of coercion and physical, sexual, emotional, psychological, economic and educational threats against an individual because of their gender or sexual identity [2]. The objective was to study gender-based violence at the "One Stop Center" unit of Fousseyni Daou Hospital in Kayes. Materials and Methods: This was a descriptive cross-sectional study that was conducted from January 1 to December 31, 2022, a period of 12 months. The study focused on survivors of gender-based violence received for consultation in the "One Stop Center" unit of Fousseyni Daou Hospital in Kayes. The data were collected on a survey form from medical records, the gender-based violence register, requisitions and medical certificates. Data were entered into Microsoft Word 2016 and analyzed using SPSS version 20.0 software. Each survivor had an identification code. Confidentiality and anonymity were respected. Results: During the study period, we collected 79 cases of gender-based violence out of a total of 8,404 cases of gynecological and obstetrical consultations, i.e. a frequency of 0.94%. The most affected age group was 11 to 19 years old with 41 cases or 51.9%. The average age was 16.54 years old and the age limits were 2 and 35 years old. In the profession, children and adolescents not in school were the most represented with 29 cases or 36.7%. Women residing in urban areas were the most represented with 55 cases or 69.6%. Single women were the most represented with 53 cases or 67.1%. Eighty-nine percent of survivors came with a requisition against 11%. Rape was the main reason for consultation with 24 cases or 30.4%. Sexual assault was the most common type of violence with 53 cases or 67.0%. In the sample, we recorded 1 HIV positive case, 2 cases of positive Hbs antigen, 2 cases of positive pregnancy test. There were two cases of surgical management with suture for cases of rape with vulvar lesions and a second-degree perineal tear. Twenty-six cases out of the 79 cases collected were prosecuted. There were about ten cases of conviction. Conclusion: Gender-based violence is a tragedy and can have psychological, physical and even obstetric repercussions in the short, medium and long term because the survivors are mainly fragile minors.

Background: This study investigates the impact of Good Corporate Governance (GCG), profitability, and carbon emission disclosure on firm value in the mining sector listed on the Indonesia Stock Exchange (IDX) from 2019 to 2022. The mining sector's significance in Indonesia's economy and the growing importance of sustainable corporate practices provide the context for this research. Methods: The study employs multiple regression analysis to analyze data from 11 mining companies. The variables include GCG mechanisms (managerial ownership, institutional ownership, independent commissioners, and audit committees), profitability (measured by Return on Assets), and carbon emission disclosure. Firm value is proxied by Tobin's Q. Results: The findings indicate that profitability has a positive and significant impact on firm value. However, GCG mechanisms such as independent commissioners and audit committees have negative effects on firm value. Carbon emission disclosure does not significantly influence firm value. Conclusion: The study highlights the importance of profitability in driving firm value but also underscores the need for effective GCG mechanisms and greater emphasis on environmental responsibility. The results contribute to the discourse on sustainable corporate practices and their implications for investor confidence, emphasizing the necessity of balanced approaches that integrate financial performance with environmental sustainability.

This article critically evaluates the intricate navigation between national sovereignty and international refugee law in Bangladesh, specifically concentrating on the nation’s mechanisms of the protracted Rohingya refugee crisis. As a non-signatory to the 1951 Refugee Convention, Bangladesh's legal obligations are initially motivated by the influence of international humanitarian norms, regional considerations, and domestic policy frameworks. This paper examines Bangladesh’s efforts to mediate its sovereign prerogatives with its moral and legal obligation to serve sanctuary to displaced populations. Through critical evaluation of legislative endeavors, governmental reactions, and the efforts of international actors such as the UNHCR, the article enunciates Bangladesh's multifaceted obstacles in its mandate to develop global refugee standards while indicating its domestic needs. The study articulates by proffering strategic suggestions aimed at liberalizing Bangladesh’s mechanisms with international refugee protection protocols, thereby contributing to both the strategy on refugee administration and the progression of legal mechanisms in South Asia.

Background: Ventilator-associated pneumonia (VAP) is a prevalent cause of morbidity and mortality in intensive care units (ICUs). Defined as a nosocomial pneumonia that occurs more than 48 hours after mechanical ventilation initiation, VAP poses significant clinical challenges. While awareness of evidence-based practices is crucial, a gap often exists between knowledge and actual practice among nursing staff. Enhanced adherence to VAP prevention protocols has been linked to reduced incidence rates. Purpose: This study aims to assess the level of nurses’ knowledge and compliance regarding the prevention of VAP in the intensive care unit of King Fahad General Hospital in Saudi Arabia. Method: A descriptive research design was employed, involving 120 ICU nurses selected through convenience non-probability sampling. Result: A total of 96 participants were recruited in this study. The level of knowledge about VAP prevention among ICU nurses was almost good as there were about 57.3% (n=55) of the nurse participants had a good and adequate information. There was significant statistical difference in the mean knowledge score based on the academic qualification but, there was no statistical difference in mean of compliance based on academic qualification. Conclusion: Insufficient nursing knowledge and compliance about VAP assessment and prevention is a serious safety concern in all healthcare settings. The study highlighted that ICU nurses showed (good) moderate knowledge towards VAP prevention.

This work investigated the potential synergy between Fly Ash (FA) and Ground Granulated Blast Furnace Slag (GGBFS) as binder solids in the manufacturing of Geopolymer Concrete (GPC), a concrete that does not contain Ordinary Portland Cement (OPC). At a ratio of 1:1, the ideal mixture of binder solids was attained. Based on absolute volume, the mix design was created using techniques akin to those found in ACI 211.1. In order to investigate the impact on the evolution of strengths, the alkaline activator content (AAC) to binder solid ratio—which is comparable to the water/binder ratio in OPC concrete—was varied in the ratios of 0.25, 0.3, 0.35, 0.4, and 0.5. For every mixture, the ratio of sodium hydroxide to sodium silicate was maintained at 1.5. To evaluate the functional relationships between the response variable (strength) and the independent variables (GPC constituents), a nonlinear regression analysis was conducted. Experimental results on workability for all mixes are in agreement with ACI 211.1 criteria. In all mixes, GPC specimens exhibited higher compressive strengths than OPC specimens; with a maximum value of 73.67 Mpa and 72.67 Mpa respectively. Nonlinear regression results provide equations that predict the strengths with excellent correlation. In addition to F-statistics that are statistically significant within acceptable probabilities.

Pure anterior dislocation of the hip in its obturator variety is extremely rare. It typically results from high-energy trauma and can jeopardize the functional prognosis of the hip if reduction is not performed urgently. We report the case of a motorcyclist who sustained an isolated anteroinferior (obturator) hip dislocation. The patient underwent reduction 4 hours after the trauma, with good clinical and radiological outcomes observed at an 18-month follow-up.

The paper uses Systemic Functional Linguistics (henceforth SFL) to conduct a transitivity analysis of the clause in the siLozi language (K21) spoken in Zambia. The paper explores how the experience of the material and non-material world is construed through the grammar of the clause. The paper draws insights from Martin and Rose’s (2003) SFL to analyse the clause in siLozi in terms of what kind of clausal activities are undertaken in the siLozi clause’s PRTs, PRSes and CIRs; how the PRTs in these PRS-types are described; how they are classified and what they are composed of. The transitivity study of the clause in siLozi reveals that just like in English, the siLozi language expresses its clausal experience through the three major PRS-types namely MaPs, MePs and RePs. The minor PRS-types – VePs, BePs and ExPs – not only exist in siLozi but also construe experience both uniquely and also similar to English. Furthermore, the discourse structures in the process-types are deliberately selected and situated for various reasons. The findings have implications in using SFL transitivity in the teaching of some aspects of grammar such as comprehension in siLozi in schools in Zambia and in other countries like Namibia where siLozi is taught.

Transfection is a critical technique for introducing nucleic acids—such as DNA, RNA, or oligonucleotides—into cells and plays a pivotal role in diverse research fields, including gene therapy, recombinant protein production, and functional genomics. This meta-analysis examines the fundamental mechanisms, methodologies, and challenges associated with transfection, highlighting advances in both viral and non-viral delivery systems, optimization techniques, and clinical applications. Viral vectors, including adenovirus, retrovirus, and lentivirus, offer high efficiency and are frequently used in gene therapy applications, while non-viral methods, such as lipid-mediated transfection, polyethylenimine (PEI), dendrimer complexes, electroporation, microinjection, and biolistic delivery, provide safer alternatives but often exhibit lower efficiency, necessitating optimization. Lipid-based transfection remains one of the most widely used methods, particularly lipofection, due to its ease of use and efficiency in commonly used cell lines like HEK293 and HeLa cells. Electroporation is effective for challenging cell types, such as primary neurons and stem cells, though high cell mortality rates necessitate careful optimization. Transfection has significantly contributed to gene therapy, particularly for genetic disorders such as cystic fibrosis, hemophilia, and spinal muscular atrophy, with viral vectors employed in CAR-T cell therapy for cancer treatment showing promising results in hematological malignancies. Recent advances in mRNA transfection have revolutionized vaccine development, exemplified by mRNA vaccines for COVID-19, demonstrating the potential for further therapeutic applications. However, challenges remain, including achieving high transfection efficiency while maintaining cell viability, especially in primary cells and stem cells, which are more resistant to transfection than immortalized cell lines. Cytotoxicity and off-target effects limit the clinical utility of transfection, particularly in gene therapy, where insertional mutagenesis poses significant safety risks. The cost of scaling transfection for therapeutic applications, such as CAR-T cell production, remains prohibitive. Future research will focus on overcoming these limitations while advancing the clinical applications of transfection for therapeutic gene delivery and personalized medicine. Overall, as new materials, technologies, and optimization strategies are developed, the efficacy, safety, and applicability of transfection techniques will likely improve, enhancing their role as cornerstones of molecular biology and biotechnology.

Distalization is a common orthodontic technique used to address Class II malocclusions, particularly those where there is an overjet due to maxillary protrusion. It’s performed to correct average to moderate class 2 malocclusions (<3mm) by retracting the maxillary teeth. This technique should be preferred in patients presenting a class II malocclusion due to maxillary protrusion or in adult patients undergoing compromise treatment. The following case report describes an adult female patient with class II subdivision in the left side treated by clear aligner (invisalign) by distalization and class II elastics. Sequential distalization protocol was used starting with the second molar, once the second molar has moved two-thirds of the desired distance, the first molar is distalized, followed by the premolars and canines. Finally, the four incisors are retracted to complete the treatment.

Background: Enteral feeding intolerance (EFI) is a critical concern in critically ill patients, associated with complications like vomiting, elevated gastric residual volumes (GRV), and delayed gastric emptying. Despite its prevalence, EFI lacks a universally accepted definition and standardized management protocols, leading to inconsistent practices among healthcare providers. Aim: This study aimed to evaluate nurses’ knowledge at Ibri Hospital regarding EFI, including its definition, causes, symptoms, and the feasibility of oral medication administration during intolerance episodes. Evidence-based recommendations were proposed to improve enteral feeding practices. Methods: A cross-sectional descriptive design was used, involving 170 nurses from inpatient departments at Ibri Hospital. Data were collected via a validated online questionnaire and analyzed using SPSS. Key knowledge areas assessed included EFI indicators, GRV thresholds, and clinical management practices. Convenience sampling was employed. Results: The study revealed variability in nurses’ understanding of EFI indicators and GRV thresholds. Vomiting was the most recognized EFI indicator, though only 62% identified it correctly. GRV threshold knowledge varied, with 61% selecting context-dependent measurements. Pediatric ward nurses demonstrated the highest knowledge, while operating theater staff scored the lowest. Training had minimal impact, except for improved recognition of vomiting as an indicator (p = 0.025). Nurses favoring early feeding initiation and timely restarting showed higher knowledge scores. Conclusions: Significant knowledge gaps and inconsistencies in EFI practices were identified. Recommendations include developing evidence-based EFI protocols, regular interdisciplinary training, and promoting collaborative decision-making. Future research should validate findings and assess the impact of standardized EFI protocols on patient outcomes.

Background: Family Medicine research is any study that addresses questions of importance to physicians with the intent to improve the care of patients. Research is essential to enhance the role of family physicians in health care systems, to improve the optimal functioning of health care systems, and to improve the health of populations in general, also serve as the basis to aid in policy-making. Aim: This study aimed to highlight the willingness of family physicians towards conducting research. Subjects and Method: Descriptive cross-sectional study with an analytic element conducted for a period from the 1st of March through the 31st of May 2021. The target population included all family physicians in Iraq. A total of 297 participants were recruited for this study. Participants were asked to fill out an electronically distributed questionnaire specially constructed for the sake of the study. Results: Females constituted 79% of the sample and 82% of the participants were less than or equal to 40 years of age. The specialists in family medicine constituted 70% of the participants; 81.5% had medical experience less than or equal to 15 years, and 52.9% worked for more than 30 hours per week. The mean of the participant response regarding the attitude questionnaire was 45.03 (±9.21). The participants with a positive attitude were 167 (56.2%). Applying multivariate binary logistic regression, the only significant association was between attitude and frequency of reading medical articles. Lack of time was the main stated barrier that obstacles to research conduction among family physicians. Conclusion: More than half of the participants had a positive attitude towards research conduction. Lack of time and health care support were the main barriers to research conduction. Increasing the frequency of research reading was the main predictor of research conduction.

Eyelid tumors are the set of lesions or growths that develop within the eyelids. They can be benign or malignant. We report the case of a 57-year-old patient who consults for a lower palpebral mass in the left eye. On examination, a nodular mass of firm consistency was found. The rest of the left and contralateral palpebral contour was normal. Management consisted of surgical resection of the tumor and histopathological examination. Anapathomopatologic examination found an inflammatory infiltrate made up of lymphoplasmacyte and neutrophil polynuclear cells in favor of a rearranged papilloma. The post-operative effects were simple and the healing took place without complications. Surgical excision allows the tumor to heal. Treatment is essentially surgical and is based on reconstruction after removal of the tumor.

Aim: To analyze the mental foramen dimensions and location for gender determination in a sample of Yemeni population. Methods: This is a retrospective study performed on 420 maxillofacial CBCT scans, 210 males and 210 females with age ranged from 20 to 60- years old. Osteometric analysis of the dimensions, shape and position of the mental foramen was performed. Results: In comparison between males and females, all mental foramen (MF) measurements were statistically significant except at the distance from the superior mental foramen to the alveolar crest. The all measurements of males were higher than females. MF with round shape was the most common between both males and females. The most common location of the MF was presented below the apices of the 2nd premolars. Conclusions: We can be concluded that the vertical and horizontal dimensions the MF and the distance from the lower border of the MF to the lower border of the mandible exhibits gender dimorphism in the Yemeni population. The shape and horizontal position of the MF do not show any difference denoting that they cannot be used for identification of gender.

Aim of the study: To study salivary immunoglobulin A and lysozyme levels and their relation to dental caries status in a group of Yemeni asthmatic children. Subjects and methods: One hundred children of both genders were enrolled in this study, aged 6-10 years. The cases were divided into two main groups: fifty asthmatic children and fifty healthy children. Every child was examined for dental caries and assessed according to WHO criteria (1997) using defs for primary teeth and DMFS for permanent teeth. Salivary samples were collected from each child in each group and analyzed for sIgA and lysozyme. The relation between them and dental caries status for primary and permanent teeth was evaluated. Results: Results showed that there was no statistically significant difference between gender distributions of asthmatic and healthy children. In addition, there was no statistically significant difference between the mean sIgA levels of both groups. There was a statistically significant difference between asthmatic and healthy children regarding lysozyme levels. This difference in mean lysozyme levels was higher in asthmatic than healthy children. Asthmatic children showed statistically significant differences regarding defs and DMFS scores, which were lower in asthmatics than healthy children. For asthmatic children, there was a statistically significant positive correlation between defs scores and sIgA levels and a statistically significant negative correlation with lysozyme. In asthmatic children, a statistically significant positive correlation existed between DMFS scores and age and sIgA levels. For healthy children, there was a statistically significant positive correlation between DMFS scores and both age and sIgA levels. Conclusion: In children with allergic asthma the salivary concentrations of sIgA and lysozyme were significantly higher and the defs and DMFS scores were lower than in healthy children.

Aim of the study: To assess the attitude and knowledge among Yemeni parents toward their child’s oral health practice and habits with associated factors. Subjects and methods: This study was carried out using three hundred self-administered structured questionnaires for parents or guardians. Demographic variables, knowledge of dental health, oral health, and dietary practices concerning dental care, and attitudes toward oral health were assessed. The correlation between sociodemographic status and oral health knowledge and practice was evaluated. Result: results showed that the mean caregiver's level of knowledge is 53.9%. Most mothers have good knowledge about the age of primary teeth eruption 71.9% and exfoliation 64.9%, the significance of primary teeth 78.4%, what causes the most common dental disease affects teeth 91.8%, and the importance of cleaning teeth 85.4%. 68.4% Cleaned their teeth, and most of them 78.4% remained to encourage their children to clean their teeth. Mothers have bad knowledge about the time to start brushing their children’s teeth 46.8% and the role of fluoride in preventing dental caries 32.2%. There was a statistically significant correlation between the level of knowledge and the mother’s education level and occupation. Conclusion: Yemeni mothers have average knowledge of their children’s oral health status. There was a statistically significant relation between the mother’s education level and the level of knowledge. The mother's education level group (Professional) ranked first with a knowledge level (73%).