A novel therapeutic use of Ethosuximide has come to light with the findings of powerful analgesic effects in experimental models as well as in humans.The analgesic effects of Ethosuximide were explored in various nociceptive models. Following intraperitoneal administration, ethosuximide dose-dependently reversed chemotherapy induced peripheral neuropathic pain and capsaicin-induced mechanical Allodynia, and produced antinociceptive effects in the rat-tail flick reflex test in male rats. Analgesia Produced by Ethosuximide is as good as that Produced by Gabapentin in Acute Pain models. Analgesia produced by extract of Ocimum sanctum is as good as that Produced by Ethosuximide, when compared with these drugs individually in acute pain models. In Neuropathic Pain induced by Ethosuximide Produces Significant Analgesia in Thermal Hyperalgesia Models and significantly reduces Cold Allodynia. The Ethosuximide in neuropathic pain relievers Thermal Hyperalgesia as well as cold Allodynia.

The peripheral intravenous (PIV) catheter is the most used vascular access device for administration of medications in hospitalized neonates. To evaluate the impact of an educational program for nurses on assessment, management, and prevention of peripheral intravenous complication in neonatal intensive care unit. A quasi-experimental research design was used in the current study. The study sample consisted of a convenience sample including all available nurses (88) at University Hospital, General Hospital and Health Insurance Hospital at Beni-Suef. Two self-administered tools for nurses; part I, socio-demographic data for nurses, part II, nurses’ knowledge regarding IV fluid and part III, nurses` knowledge regarding IV complications and neonate's needs of management and observational checklist for nursing practice about IV infiltration or extravasation in neonates. The findings revealed that there was a highly significant difference in the pre and post-intervention program and their knowledge and practice, the study stated that there was an improvement in their knowledge and practice towards prevention and management IV complications. Educational intervention had a significant role in increasing knowledge and practice of universal precautions among nurses. It is recommended to exert more efforts in developing and applying similar educational endeavors for nurses in NICUs these educational initiatives need to be boosted periodically to ensure sustainability of their positive effects on knowledge and practice

The prevalence of nutritional deficiency especially the iron deficiency anemia is very common in pregnant females of developing countries, more so in the rural and tribal population. We in the present study tried to evaluate the prevalence of anemia in 300 females in 1st, 2nd and 3rd trimester attending ANC in Rajiv Gandhi Institute of Medical Sciences and Hospital [RIMS], Adilabad. The Institutional Ethical committee permission was obtained for the study. 100 patients in each of the three trimesters were included in the study all the pregnant ladies were healthy without any significant medical disorders. The blood samples were collected from the peripheral vein in 5ml vacutainer and send to the Department of Pathology for examination. The Department of Pathology, RIMS Adilabad uses 5 part hematology cell counter (Sysmex Xn 1000 manufactured by Sysmex India Pvt. Ltd Mumbai) to obtain all the hematological parameters. The mean levels of hemoglobin in n=100 patients of 1 trimester were 8.38 ± 1.5 gm/dl, the mean levels of Hb in n =100 patients of 2nd trimester was 8.34 ± 1.24 similarly the mean Hb levels of n=100 patients in the third trimester was 7.75 ± 1.02. The hemoglobin levels of 10.0 – 10.9 gm/dl was classified as mild anemia in our study 10.83% of pregnant ladies had mild anemia. Between 7.0 – 10.0 it was classified as moderate 76.67% of pregnant ladies had moderate anemia, < 7.0 gm/dl was classified as severe 12.5% had severe anemia and < 4.0 gm/dl was classified as very severe (decompensated) anemia no case of very severe anemia was present in this study. The presence of nutritional deficiency anemia is very common in the tribal pregnant females of Adilabad. Although all the pregnant females receive duly the dose of iron and folic acid supplementations during the Antenatal care there needs to be good nutritional supplementation provided to reduce the burden of anemia in the pregnant females of this area.

This study aims to examine and analyze the influence of transformational leadership, organizational culture, and work motivation on employee performance of PT XYZ. The sampling method used is proportional random sampling. From a population of 100 employees with a sample of 80 employees. The method of analysis used in this study is multiple linear regressions. The results showed that transformational leadership, organizational culture, and work motivation together (simultaneously) have a significant effect on performance. Partially transformational leadership and organizational culture have a significant positive effect on performance. Organizational culture and work motivation have a significant positive effect on performance.

The blood pressure changes are sometimes reflected by changes in Intra-ocular pressure. We in the present study tried to evaluate the changes in IOP with the change in blood pressures in borderline hypertensive to known hypertensive patients graded according to recent ACC/AHA guidelines of hypertension in male and female patients visiting Rajiv Gandhi Institute of Medical Sciences [RIMS], Adilabad. The study was carried in the Department of General Medicine and Department of Ophthalmology. A total of (n=222) patients were involved in the study. Subjects with the history of glaucoma, ocular hypertension, corneal abnormalities or those who underwent ophthalmic surgeries were excluded from the study. Systolic blood pressure was determined at the point at which the Korotkoff’s sounds become audible (first phase) whereas the diastolic BP was measured at the point at which the sounds suddenly become faint (fourth phase of Korotkoff’s sounds). Blood pressure measurements were determined by taking the mean value of three readings at 30 minutes interval. The IOP was measured in the Department of Ophthalmology, of both eyes with help of Goldmann applanation tonometer using 2% fluorescein eye drops by the same examiner to avoid any difference. In this study, we included a total number of (n=222) patients out of which males were (n=120) 54.54% and female were (n=102). The mean age of the individuals involved in the study was 52.25 ± 12.5 years. The overall mean IOP in males was 18.85 ±6.65 [95% CI 17.7 ± 20.0] similarly the overall mean IOP in females was 17.54 ± 5.83 [95% CI 16.4 -18.7]. The differences between the IOP of male and female were statistically insignificant. The Pearson's correlation coefficient was measured for each subgroup of hypertension among the male the all the subgroups showed the positive correlation of IOP with blood pressure and a strong correlation was shown by Hypertension stage II. In females, the correlations were also positive in all subgroups however in hypertension stage II showed weak to the moderate correlation coefficient. There is a strong positive correlation between the blood pressure and IOP, especially in males. Considering IOP as one of the screening means of glaucoma detection we would recommend that every hypertensive patient undergo IOP check regularly to prevent glaucoma.

Parenting styles have been cited to have brought conflict between young people and their parents on values or ethical principles, and morality or religion. This is an element which is present in almost all cultures. Therefore, parenting style may have an influence on adolescent self-esteem, autonomy, independence and openness. This study focused on the influence of parenting styles on adolescent autonomy and selfesteem among students in secondary schools in Wareng district, in Uasin Gishu county – Kenya. It views family parenting styles as the main precursors towards adolescents‟ decision making, self-reliance and conformity. The objective of the study was to establish the relationship between parenting styles on adolescent autonomy and selfesteem. It targeted a population of 23027 adolescents. A sample size of 394 was drawn from 10 secondary schools through stratified random sampling. The researcher employed causal-comparative research design. This research was based on Carl Rogers‟ Self Theory and Adult Attachment Theory by Bowlby, where both theories are used to explain autonomy and self-esteem development. A self-administered questionnaire was used, examining different parenting styles and aspects of autonomy, scored on a five-point Likert scale and a self esteem questionnaire, scored on a threepoint scale. To ensure the validity of the research instruments, the researcher used expert judgment. On obtaining complete data, it was organized, edited, tabulated and coded to facilitate effective analysis. Hypotheses were tested at 5% significance level. Data analysis was done using Statistical Packages for Social Sciences (SPSS), where both descriptive and interferential statistics were used. The findings revealed that, there was a significant positive relationship between authoritative parenting style and adolescent autonomy and self-esteem, while authoritarian parenting showed no significant relationship with adolescent autonomy. Further, the findings revealed that permissive parenting style does not yield autonomous adolescents, while uninvolved parenting has an influence on adolescent autonomy. However, the study generated information on parenting styles, self-esteem and autonomy related aspects, and these might be of value to school stake holders, more so the parents who have a direct influence on adolescent autonomy.

A zero coronary calcium score was obtained in out study in 28.33 % participants of which only 4 (13.35% of cases) patients who developed ACS had a zero CACS, while 13 (43.3% of controls ) people among control had a zero CACS. In this study, we analysed the distribution of Coronary artery calcium scores in patients of ACS who do not have traditional risk factors namely obesity, diabetes, smoking, dyslipidemia, hypertension was significantly different as compared to asymptomatic people without CAD and having none of above mentioned risk factors. Even though there were no traditional risk factors coronary calcium scores were significantly higher in patients who developed ACS as compared to controls

This study aims to determine the relationship between employee motivation and the level of urban services, especially the service of urban garbage at the Environmental Office of Gorontalo City. The research method using descriptive method, data collection techniques using questionnaires and direct observation in the field. While data analysis using regression analysis technique and correlation with research scope on employee motivation dimension and service level of urban area. The result of the research showed that employee motivation motivation 57,14% employee have high work motivation with average score 81,8 and 42,86% employee have low work motivation. While in terms of urban service level shows that as many as 27.14% of employees stated high service level with an average score of 63.86 and as many as 71.43% said stating employees the level of service is as well as 1.43% said stating employees low service levels . correlation coefficient r = 0.346, there is correlation between employee motivation and level of service of urban with weak category. Regression equation Y = 31.4 + 0.397 X or contribution / influence of independent variable of employee motivation to dependent variable of urban service level equal to coefficient b = 0,397. There is a positive relationship between employee motivation and the level of urban services but the motivation to the employees of the Gorontalo City Environmental Office has little effect on the level of urban services.

Adjuvants are commonly used during general anesthesia in order to reduce the requirements of the general anesthetics. Dexmedetomidine is one of an important general anesthetic adjuvant used because of its useful properties like sedative, analgesic and anxiolytic. It has other important useful properties like cardioprotection, neuroprotection and minimal respiratory depression. We in the present study tried to evaluate the efficacy of dexmedetomidine in different concentration when used as an infusion during general anesthesia in patients undergoing routine abdominal surgeries. Methods: the study was conducted in Rajiv Gandhi Institute of Medical Sciences and Hospital [RIMS], Adilabad. The patients were selected from those undergoing abdominal surgeries. They were randomly divided into three groups. Group A (n=20) patients acting as controls received IV saline 10ml. Group B received Dexmedetomidine 0.5 µg/Kg/hr IV and Group C received Dexmedetomidine 1 µg/Kg/hr IV. Anesthesia was maintained with N2O to O2 mixture of 60:40. MAP values were maintained within 25% of the baseline values. Recovery times from tracheal extubation, modified Alderete score, VAS scores, tolerating liquids, and passage of flatus was noted. Results: The mean duration of surgery in Group A was 145.45 ± 20.06 minutes, mean duration of anesthesia was 180 ± 25 minutes. The mean duration of infusion of dexmedetomidine was 160 ± 20. For group B the values were 130.12 ± 24.75, 160.0 ± 22.0, and 140 ± 90 minutes respectively. The values for group C were 121.59 ± 18.16, 145 ± 26 and 125 ± 15minutes. The P values between group A and C were significant in Mean duration of anesthesia and mean duration of infusion. The time to suction catheter response was significantly higher in Group C. The modified Aldrete scores in Group B and Group C were found to be significant when compared to Group A similarly postoperative nausea and vomiting was significantly lesser in group C and VAS scores of pain were also significantly lesser in the Group C as compared to Group A and B. conclusion: Dexmedetomidine is low concentrations may be useful to provide sedation and mild analgesia at the same time preserving the cardiovascular and respiratory functions. Therefore dexmedetomidine when used as a general anesthetic adjuvant during routine abdominal surgeries reduces the sevoflurane and opioid requirements and results in better recovery of the patients.

The article examines the relationship between attitudes of staff members towards gender differences and high job positions relating to employee performance and institutional development in selected Universities of Western Uganda. The study adopted an observational, cross-sectional exploration design with both quantitative and qualitative as paradigms in order to describe the data and its characteristics [6]. Questionnaires and an interview guides were employed to gather information from the respondents. Data was analyzed using frequencies, percentages and bar graphs. The study findings showed that there was a positive relationship between gender differences in decision making and top management positions. The study findings recommended that there is need to ensure building the capacity of women by improving their literacy and leadership skills, give men and women equal opportunities and treat them equally and have equal access to top jobs in all institutions of learning, the study also suggested including both men and women in policy making processes, through consultative ways in high level decision making.

Sympathetic & Parasympathetic test status may be changed during follicular and late luteal phases of menstrual cycle due to fluctuations of serum estrogen and progesterone levels. Objective is to find out. Sympathetic & Parasympathetic tests between male medical students & luteal phase of menstrual cycle in female medical students. This study evaluates autonomic function tests in different phases of menstrual cycle and concludes that sympathetic activity is highest during luteal phase and lowest in the follicular phase. It is concluded that there is higher sympathetic activity in males as compared to females

The study is centred on understanding the underlining factors influencing consumer’s choice in purchasing patterns. Contemporary consumers are believed to reflect elements of rationality and irrationality in their consumption preferences. So the study assessed the choice motives which prompt the patronage of some selected household items amongst university students. These items are phones, laptops and consumables. The students were randomly selected on gender basis. Assessed factors include peer influence, trends, affordability, advertorials, needs, lifestyle, health, religion, income and product packaging. Findings revealed that the influence of rationality and irrationality are inherent in consumer behaviours, but personal interest of consumers at a particular point in time takes precedence.

Fractures fixation with open reduction and compression plates is frequently used in diaphyseal radius/ulna fractures because of advantages like proper alignment, maintaining length and rotational alignment. This study compares the outcomes of treatment of fracture cases with dynamic compression plates and intra-medullary nailing by a square nail in mid shaft radius/ulna fractures. The study was conducted in Rajiv Gandhi Institute of Medical Sciences, [RIMS] Adilabad during the period from March 2014-Dec 2017. The study involved n=55 cases of which n=31 were male and n=24 were female. The common age group involved was 31- 40yrs contributing to 41.81% (n=23) of cases followed by 23.63 % (n=13) cases in 21 -30 yrs age group and 20% (n=11) cases in 41 – 50 yrs age group. Most common type of fracture was Transverse type in 37 cases, oblique in 10 cases and comminuted in 8 cases. Dynamic compression plates were used in 61.82% (n=31) of cases, IM nail was used in 38.18% (n=24) of cases. Dynamic compression plate treated patients had overall 94.11% cases in Excellent and good results and 90.48% of the IM nail treated patients had excellent and good results. To conclude Treatment of diaphyseal forearm is challenging as it because of lack of censuses regarding treatment and it requires judicious selection of cases for using compression plates or IM nail. Within the limitation of the present study, it may be concluded that dynamic compression plate offers better overall outcomes in the treatment of diaphyseal radius/ulna fractures

The phenomena of labour migration from South Asia to GCC countries are result of structural changes in the demand and supply of labours in the GCC countries in the context of different time and space. The oil producing countries of Gulf Cooperation Council (GCC) is the largest destinations for South Asian migrant labourers. South Asian countries mainly India, Pakistan and Bangladesh are the largest source of origin of migrants in GCC Countries. The huge stock of temporary South Asian migrants led to largest inflow of remittances in origin countries. Among the South Asian countries; India is the largest source for supplying of migrant labourers in the GCC countries as well as top remittances recipient country. The labour migration from India to GCC countries is recent phenomena began with incident of oil boom in the GCC countries in 1973. In the initial phase of labour migration from India to GCC countries was dominated by Kerala but recently there are regional variations showed in the labour migration from India to GCC countries. In these entire discussion, paper attempts to present an analysis and overview of the nexus of migration and remittances in South Asian countries with special references to India.

WBC counts increases in significant number of patients with acute myocardial infarction. Widely available WBC count test can be used as prognostic marker in acute myocardial infarction. To study correlation between complications of acute myocardial infarction and WBC count. Total 50 diagnosed cases of acute Anterior Wall MI were studied. Complications after acute myocardial infarction were more in elevated WBC count. Elevated WBC count within 24 hours was associated with high rate of complications after acute myocardial infarction; however to established association between complications of acute myocardial infarction and WBC count we need further larger study