The current clinical study was planned to assess the efficiency of Jeemootakaphala Avapeedaka and Pradhamana Nasya in Kosthashakhashrita kamala. The study was completed on 30 patients diagnosed with Kosthashakashrita kamala of either sex, among the age faction of 20 to 60 years who were arbitrarily chosen. The patients were categorized into 2 groups i.e Group A & group B. Jeemootaka phala Avapeedaka Nasya was given to group A, while Jeemootaka phala Pradhamana Nasya was administered in group B. The dosage of Nasya was -1.5 ml in every nostril in group A, 65 mg in every nostril in group B. The evaluation was made before the treatment and after treatment. Patients were followed up after 7 days of Nasya. Hence whole study period was 15 days. Both Nasya showed considerable improvement in Kosthashakhashrita kamala. Clinical efficiency of group A was better than to group B however statistically both groups showed similar efficacy.

Solid lipid nanoparticles (SLNs) are at the rapidly developed field of nanotechnology with a few potential applications in drug delivery, clinical medication and research, and additionally in other distorted sciences. Because of their small size-subordinate properties, lipid nanoparticles offer the likelihood to grow new therapeutics. The capacity to loaded drugs into nanocarriers offers another model in drug delivery that could be utilized for optional and tertiary levels of drug targeting on. Consequently, SLNs hold extraordinary advantage for achieving the objective of controlled and site specific drug delivery and henceforth have pulled in wide consideration of analysts. The current review describes the role of solid lipid nanoparticles on the pharmacokinetics of poorly soluble antihypertensive drugs. In the event that suitably examined, solid lipid nanoparticles may open new areas in treatment of hypertension with improved oral delivery

Taking the position that writing can be an important skill to foster knowledge building pedagogy; this article explores reading news through mobile applications as a supportive tool for this purpose. Fifteen language learners as participants of the experimental group used two popular news applications on their mobile phones for reading as a pre-task activity that made them outperform their counterparts in the control group in terms of using facts in essays. No significant difference, however, was observed in the overall writing ability of two groups despite considerable progress of the variable content in the experimental group’s favor.

Ankylosing spondylitis and rheumatoid arthritis are the most common chronic inflammatory rheumatism. Their localization at the level of the hip stresses severely the functional prognosis. We report a retrospective series of 40 total hip prostheses performed in 32 patients with inflammatory coxitis, collected in the Traumatology and Orthopedics Department at the Mohammed V Military Hospital in Rabat between 2008 and 2016. The average age at the time of the intervention was 42 years with a clear male predominance. All patients were followed in consultation with a clinical and paraclinical examination. Coxitis following ankylosing spondylitis is the most frequently encountered in our series (65.6%). The rating of Postel Merle d'Aubigné was used to assess the functional status of the hip before and after surgery. The total hip prosthesis was cementless in 37 cases and cemented in 03 cases. The clinical results for the 32 patients after a mean follow-up of 04 years were very satisfactory in (88%) of the cases. The objective of this study is to evaluate our functional results and to show the interest of total hip arthroplasty in this type of pathology, in order to improve the quality of life of these often young patients

This research investigates the impact of the global financial crisis on the performance of Nigerian stock market from 2004 to 2013. The main aim of the research was to examine the impact of global financial crisis on the performance of the N.S.E. Data for this research was sourced from a secondary source. The data were statistically analyzed using descriptive analysis and Kruskal-Wallis H test statistical tools. The analysis showed that Global Financial Crisis has no significant effect on Market Capitalization, value and volume of shares traded on the floor of the N.S.E. From the analysis, the researcher concludes that Global Financial Crisis has no significant effect on market capitalization, value of shares traded and the volume of shares traded in Nigerian stock exchange.

This complete enumeration, cross-sectional comparative record-based study was conducted at a municipal medical college in Maharashtra state, India. First-year MBBS students undergo formative assessment (one terminal examination and one preliminary examination) before they appear for First MBBS University examinations (summative assessment). Marks scored by the First-year MBBS students in terminal and preliminary practical examinations during the seven year period (2011-2017) were statistically analysed. In the terminal practical examination, the gender difference in the average marks scored in terminal practical examinations was statistically significant (Z=2.226; p=0.026) only for Batch 2013, while in the preliminary practical examination the gender difference was statistically significant for Batch 2011 (Z=2.094; p=0.036) and Batch 2017 (Z=2.139; p=0.032). The marks obtained in preliminary practical examination exhibited less variability as compared to that in the terminal practical examination. This study may serve as a springboard towards further research on student assessment in the subject of Physiology

The objective of the study was to observe the various clinical features, histopathological and immunofluorescence findings in patients with autoimmune vesiculobullous disorders. The overall M: F ratio of autoimmune vesiculobullous disorders in the study was 1: 1.4. Trunk was the most common site of involvement in all types of autoimmune vesiculobullous disorders. Overall trunk was the most common site of onset of lesions in autoimmune vesiculobullous disorders but in pemphigus vulgaris mucosal onset is more common than trunk and extremities. Incidence of autoimmune vesiculobullous disorder was 0.11% of the total number of patients attending the skin OPD. Pemphigus vulgaris constituted the most common subtype of autoimmune vesiculobullous disorder in this study, followed by pemphigus foliaceus. Pemphigus group of diseases were most common in the 4th decade while bullous pemphigoid was most common in the 7th decade. Histopathological examination showed features typical of each subtype of autoimmune vesiculobullous disorder.

A combination of ethinylestradiol and drospirenone is used as an oral contraceptive and also for the treatment of premenstrual dysphoric disorders, acne and hirsutism. In this study, a derivative spectrophotometric method has been developed and validated for the simultaneous determination of drospirenone and ethinylestradiol. First order derivative spectrum was used for the determination of ethinylestradiol at 211 nm and drospirenone at 298 and 302 nm. The developed method was linear over the concentration range of 0.25-2.5 μg/mL and 20-200 μg/mL for ethinylestradiol and drospirenone, respectively. The within-day and between-day precision and accuracy were acceptable for both compounds (CV<2.5% and error<2.4%). The proposed method was used for simultaneous determination of ethinylestradiol and drospirenone without any separation before analysis

Employees are the major drivers of any form of business and good employee performance is the most important need for the current competitive business environment to run successfully. Many organisations have started to attach a great emphasis towards the attitudes of workers towards the various instruments they use for performance appraisals. Performance Management and Performance Appraisal are very important tools; it helps to motivate employees to work hard and improves overall company’s productivity. The need to design instruments that motivate the employees through the entire of performance management process cannot be overemphasized.

In present study an attempt has been made to prepare new polymers depending on Cellulose viscous pulps to study the adsorption activity for removal of heavy metal ions from single aqueous solution. Barley and Corn Straw have been used for the extraction of crude pulps. Grafted viscous pulp has been prepared by using acrylamide as a monomer and benzoyl peroxide as an initiator in different ratios at different conditions of temperature and time. Epichlorohydrin was used as cross linking agent under the optimum conditions of grafting for the preparation of Grafted cross linked viscous pulps. The grafting percentage, grafting efficiency percentage and swelling behavior of new polymers were also studied. The structures of these compounds were established by using FTIR and elemental analysis. For the removal of chromium and nickel ions from an aqueous single metal solution the graft pulp copolymer and grafted crosslink viscous pulps were used as adsorbents. The results of the present study revealed that the ratio of pulp to monomer 1:4g/g, ratio of cellulose to initiator 1: 0.3g/g, grafting time 3 hours and grafting temperature 70 ◦C showed the optimum conditions of grafting. All the polymers synthesized in the present study showed the activity to remove heavy metal ions from an aqueous solution and the maximum activity have been shown when the cross linking agent was used in the synthesis

Abstract: The purpose of the study was to find out the effect of specific training on cholesterol among university hockey players. To achieve this purpose of the study, thirty men hockey players were selected as subjects who were from the various faculties, Annamalai University, Annamalainagar. The selected subjects were aged between 19 to 24 years. They were divided into two equal groups of fifteen each, Group I underwent specific training and Group II acted as control that did not participate in any special training apart from their regular sports and games practices. The subjects were tested on selected criterion variable such as cholesterol prior to any immediately after the training period. The selected criterion variable such as cholesterol was to assess body fat monitor. The analysis of covariance (ANCOVA) was used to find out the significant differences if any, between the experimental group and control group on selected criterion variable. The 0.05 level of confidence was fixed to test the significance, which was considered as an appropriate. The result of the present study has revealed that there was a significant difference among the experimental and control group on cholesterol.

Photoxidation of palm oil, like other forms of oils/lipids oxidation has adverse effects on the physicochemical qualities of the oil including depletion of essential antioxidants and formation of free radicals which could be injurious to tissues. Unfortunately, this widely consumed edible vegetable oil is usually stored or displayed for sale in plastic containers under direct sun light and unknowingly subjecting the oil to photoxidation. This work therefore sought to evaluate the possible effect of long term consumption of palm oil exposed to light on some reproductive parameters in male wistar rats. Male wistar rats weighing 85g to 120g and aged 19 to 23 weeks were randomly divided into a control and photoxidised palm oil (PPO)-fed groups of five rats each. The control group was fed on normal rat chow while the PPO diet group was fed on photoxidized palm oil diet. The duration of feeding was 13 weeks after which the rats were euthanized, blood samples collected while testes were harvested from them for determination of relevant parameters. The result showed a significantly reduced seminal pH in the PPO-fed group compared with control (P<0.01). Sperm motility (%) and viability (%) were significantly decreased (P<0.01 and P<0.01 respectively) in the PPO-fed group compared with control. The PPO-fed group had significantly decreased (P<0.001) sperm count and a significantly increased percentage of morphologically defective sperm cells (p<0.05) compared to the control. Serum testosterone, follicle stimulating hormone (FSH) and Luteinizing hormone (LH) were significantly decreased (P<0.001, P<0.01 and P<0.001 respectively) in the PPO-fed rats compared with control. In conclusion, long term consumption of PPO diet impairs reproductive function in male wistar rats

This research aims to determine the effect of emotional intelligence, complaining behavior and job satisfaction on the performance of employees. The object of this research is the employee at the office of Dinas Penanaman Pelayanan Modal Terpadu Satu Pintu Kota Tangerang Selatan. This research was conducted on 86 respondents by using quantitative descriptive approach. So the data analysis used is statistical analysis in the form of multiple linear regression test. The results of this study indicate that partially and simultaneously, emotional intelligence, complaining and job satisfaction have significant effect on employee performance at the office of Dinas Penanaman Pelayanan Modal Terpadu Satu Pintu Kota Tangerang Selatan.

We propose a non-monotone wedge trust region method for derivative-free optimization. Wedge trust region method based on traditional trust region is designed for derivative-free problems, and the non-monotone strategy is efficient to solve the trust region method. This paper combined the non-monotone strategy into wedge trust region methods, and the computational results proved the efficiency of the new composite strategy.

A simple, precise and gradient RP- HPLC method has been developed and validated for Aciclovir raw and in tablet formulation. The proposed method was validated to obtain official requirements including accuracy, linearity, precision, selectivity and stability. The estimation was developed on C(18) column reversed-phase using the mobile phase composition as Phosphate buffer: methanol in the ratio (60:40 %. v/v). 1ml /minute was the flow rate and the maximum absorption were observed at 290 nm using Shimadzu SPD-20A Prominence UV-Vis detector. Aciclovir showed a precise and good linearity, the concentration range was 5-25 μg/mL. The RP-HPLC, assay showed the highest purity ranging 99.59 to 100.97% for Acyclovir tablet formulation. 100.19 % was the mean percentage purity. The Aciclovir retention time was found to be 3.01 minutes. The method accuracy was showed by statistical analysis.