Geography textbooks are an important tool for geography teachers to carry out classroom teaching. Full understanding of textbooks can help teachers flexibly choose the teaching contents and better achieve teaching goals. Taking the chapter of “Climate” as an example, this paper analyzed the textbook from four aspects: internal and external relations of knowledge structure system, requirements for curriculum standards and teaching goals, the key and difficult points and teaching hours assignment, picture and text structure of the textbook. The article also puts forward three suggestions: (1) Junior middle school geography teaching should link to real life; (2) “Activities” in the textbook should be combined with the “Text”; (3) Summarize the knowledge points in the form of tables.

Normal-Phase High Performance Liquid Chromatography method was developed for determination of Rapamycin, Temsirolimus Regio isomer (monoester) and Temsirolimus diester in Temsirolimus drug and pharmaceutical formulations. The separation was accomplished on YMC Pack SIL (250 x 4.6 mm, particle size 5μm) column under isocratic mode. The column oven temperature was set at 35° C and Auto sampler temperature used at 5°C. The mobile phase is a mixer of n-hexane, ethanol and trifluoroacetic acid in the ratio of 90:10:0.01 and PDA detector set at 280 nm used for detection. The retention times of Rapamycin, Temsirolimus peak, Temsirolimus monoester and Temsirolimus diester peaks are 12.29, 21.24, 33.11 and 51.91 min. respectively. The method has been fully validated and is linear. Results of analysis are validated statistically and by recovery studies. During the process development of Temsirolimus, three process impurities (Rapamycin. Temsirolimus monoester and Temsirolimus diester) are detected by high performance liquid chromatography (HPLC). This method offers advantages over using photodiode-array UV detection (LC-PDA) for the determination of peak purity, namely components with similar UV spectra can be distinguished, the molecular mass of the impurity can be determined, and structural data can be obtained by using LC-MS. The result of studies shows that the proposed normal phase-HPLC method is found to be precise, linear, accurate, rugged, selective, specific, and robust. Hence this method may be used for the routine analysis in bulk drug and in its pharmaceutical dosage forms.

This study sought to investigate the challenges faced in mother tongue education in selected Primary schools in Nandi County, in the Republic of Kenya. Mother tongue education is usually taken as a basic human right, but despite the importance of this education myriad of problems bedevil its execution. Challenges in mother tongue education have not only been reported in many fora in Nandi County but also elsewhere in Kenya; however, no systematic study has been carried out to document these challenges, their nature and their causes. The main objective of the study was to find out the challenges of mother tongue education in Nandi County and the possible solutions to these challenges. The study adopted a case study design against a backdrop of mother tongue theory by Butzkamm (2000) which advances the argument that mother tongue education forms the basis of a child‟s acquisition of knowledge, additional languages and self-expression. This theory is built on the foundations of arguments raised by Tangas and Toukomaa(1976) claiming that a certain threshold of first language competence is needed for second language learning. A stratified random sample of 20 Head teachers, 20 lower Primary SchoolTeachers, and 5 education officials was drawn from selected schools in Chesumei sub-County in Nandi County. The main instruments of data collection were structured and semi-structured questionnaires. Data was organized and analyzed using descriptive statistics. The study identified three major challenges facing the implementation of mother tongue education in Nandi County namely: attitude of education stakeholders; teacher related factors and lack of instructional materials. The results of this study are expected to benefit scholars in applied linguistics, ministry of education and policy makers in education.

Atherosclerosis is one of the major causes of increased morbidity and mortality associated with coronary artery disease, cerebrovascular accidents, and peripheral vascular diseases. Dyslipidemia is one of the important causes that result in atherosclerosis. The incidence of atherosclerosis has been on the rising recently. Therefore prevention of dyslipidemia can decrease the development of atherosclerosis. Aims: The study was undertaken to determine the efficacy of atorvastatin alone and its combination with omega-3 fatty acids in the management of hyperlipidemia in patients attending a tertiary care hospital. Methods: This study was a cross-sectional prospective study conducted in the Department of Pharmacology and General Medicine, Kakatiya Medical College and Hospital, Warangal. The patients were selected from those visiting General Medicine OPD and diagnosed with hyperlipidemia. Sixty patients in the age group of 20 – 70 yrs, were recruited based on inclusion and exclusion criteria. They were divided into two groups. The Group I included the patients receiving Tab. Atorvastatin 10mg/day and Group II Atorvastatin 10mg/day plus Cap Omega-3 fatty acids 600mg/day for the duration of six months and follow up were done every month. Efficacy of treatment was assessed by the changes in laboratory parameters of Total cholesterol, Triglycerides, HDL-C, LDL-C, and VLDL-C. Results: The efficacy of combination therapy i.e., Atorvastatin plus Omega-3 fatty acids showed a statistically significant rise in HDL cholesterol with the mean percentage difference of 4.24% when compared to monotherapy with Atorvastatin. The efficacy of other parameters like total cholesterol (TC), LDL cholesterol, VLDL cholesterol, and triglycerides (TG'S) levels with the low dose of omega-3 fatty acids in combination therapy was not statistically significant and produced nearly identical alterations in serum lipoprotein levels when compared to monotherapy. Conclusion: Although statins are being used as first-line therapy for hyperlipidemia and in patients with elevated triglycerides. For patients with elevated LDL-C and low HDL-C combination therapy appears to be a better option. Thus omega-3 fatty acids may be a potential supplement for combination therapy apart from niacin and fibrates.

Education is a key component of a country’s developmental process. Inclusive education is a kind of education wherein all students including special needs (SN) learners attend and are welcomed by their neighborhood schools in age– appropriate regular classes and are supported to learn to contribute and participate in all aspects of life at school. Neighborhood public schools being at the heart of our communities are essential for quality inclusive education system. Special Needs learners who can benefit from public schools should not be denied the chance to access education nor be taken to special schools. However, inclusive education has been experiencing challenges which may undermine the program’s objectives if not well addressed. The extent to which these challenges could be impacting negatively on inclusive education policy in Kitale Township is however not clear. This is the gap to be filled. The Social Learning Theory guided the study. The study adopted descriptive research design. Questionnaires, interview schedules, and observation checklists were employed in data collection. The target population was 36 head teachers in the public primary schools in the township and 50 SN teachers. The sample size was 76 respondents selected using purposive and simple random sampling. Validity of data collection tools was determined through pilot study and assistance from supervisors. Reliability was tested using the test - retest method and the obtained value was .92. Hypotheses were tested using regression analysis at .05 level of significance. The study found that curriculum factors, teacher attitude, and social interaction had a significant influence on effective implementation of inclusive education policy. The study, therefore recommends more teachers to be employed to handle the large classes, the TSC to consider teachers handling SN learners in inclusive settings for special duty allowances being given to their counterparts in special schools and the curriculum to be evaluated to enhance effective implementation of inclusive education. In addition, review should be done on the part of funding to enable the acquisition of physical facilities and learning materials in public primary schools. Finally, parents, local communities and other education stakeholders should be educated on their roles in the implementation of inclusive education.

The volatile compound composition of food provides an indication of the benefits that this food can provide to the consumer. Thus the present study aimed at identifying the bioactive compounds present in formulated fermented diet made from 20% red kidney bean (Phaseolus vulgaris L.), 60% mung bean (Vigna radiate), 10% irish potato (Solanum tuberosum), and 10% ripe fresh papaya (Carica papaya) fruits inoculated with different concentrations of Lactococcus lactis sp. (Lc. lactis sp.) strain using the Gas Chromatography- Mass Spectrophotometer (GC-MS). The formulated diet consisted the control diet containing no lactic bacteria, diet 1 (1 × 106 CFU/ml), and diet 2 (2 × 106 CFU/ml). The results of the GC-MS revealed the presence of twenty volatile compounds in each diet. Five compounds namely Benzyl Alcohol; 2-propyl-1-pentanol; 1,3-diethyl benzene; 1-Tridecyn-4-ol; Phthalic acid, and cyclobutyl isobutyl ester were identified in all diets. Three volatile compounds namely Benzyl alcohol, 2-propyl-1-pentanol, and 1,3-diethyl benzene were identified as the dominant compounds in control; whereas two (Phthalic acid, cyclobutyl isobutyl ester, (E)-9-Dodecenoic acid, methyl ester) and three more (9.12-Octadecadienoic acid, methyl ester; 9-Octadecenoic acid (Z) -, methyl ester, and Tetradecanoic acid, 10,13-dimethyl-, methyl ester) bioactive compounds were detected in diet 1 and diet 2 respectively. Benzyl alcohol was the principal dominant bioactive compound in all the diets. The present study indicates that inoculation and increasing in the concentration of lactic bacteria in diet led to the identification of 2 and 3 other major volatile compounds with biology activities which could be highly important in pharmacology and nutraceuticals.

In the recent days Internet has become an essential part of life. It has revolutionized communications, to the extent that it is now our preferred medium of everyday communication. In almost everything we do, we use the Internet. Chronic usage of internet affecting physical health conditions like weight gain etc., and this is causing the greatest problems among the young individuals. The main purpose of this study is to study the relationship between internet usage frequency in the University students on our GITAM University students with their BMI. The present study consists 100 Medicine students which were differentiated as males and females (43 Males and 50 Female students). Some of the students who are not responding for all the questionnaires are excluded (07 Students). Different questions were asked to the students in the class environment. A significant association was found between BMI and the intense internet usages (>5-7hrs/daily), with F value 3.55 and p value <0.05. Out of 93 students, 15 students with high internet usage (>5-7hrs) and 31 students with moderate internet usage (3-5hrs) showed positive correlation between increased internet use and obesity.

In reference to theNational Standards of Teaching Quality for Undergraduate Business English Majorsissued by the Chinese Ministry of Education, this article holds that the publishing of Business English Reading textbooks should emphasize the following five aspects: 1) reflecting the requirements for talent cultivation in theNational Standards; 2) compiling textbooksbased on the principleof "theme plus interaction"; 3) giving consideration to the "integration of course and certificates"; (4) building multi-modal and three-dimensional teaching materials; and 5) enhancing cooperation of publishers, schools and industries. This research result can also give reference to the publishing of other teaching materials.

This study was conducted to: 1) Conduct a feasibility test for developingaccounting learning through media and accounting teaching materials. 2) Implement or implement a model in accounting learning in class. 3) Evaluate accounting learning as a student performance measurement tool. This study uses "Research and development methods or R&D cycles, which are carried out in two years. Qualitative data methods use descriptive analysis. Based on observation results indicate that student-learning activities tend to only listen to lecturers' explanations, record and work on problems. For that diverse and innovative learning activities are needed. For this purpose, instructional materials and learning media are designed through 1) expert review 2) small group trials and 3) Field trials using experiment methods through initial test and final test. And the results of trials from small groups and field tests, will be made improvements in the design of teaching materials and learning media. The instruments used in this study are questionnaires. The targeted results are the implementation of accounting learning models with ADDIE models, with teaching materials, and learning media interesting and interactive accounting if to improve the quality of accounting learning. Therefore, the need for innovation in learning accounting through the ADDIE model to assist lecturers, in creating effective, efficient, and attractive learning programs so that the results of introductory learning accounting can be achieved.

One of the objectives of the preparation of the Tax report is to provide information to parties who need it that will be used to make comparisons, assess the ability of a company, and as a guide for decision-making. In order to fulfill the above objectives, financial reports must be comparable. These comparisons can be done in two ways, namely horizontal and vertical. Horizontal comparison is a comparison of a company's tax financial statements with other companies for the same period, which in its concept can easily be used, in which the preparation uses existing software. This study aims to develop a tax accounting learning model using the Computer Tax program as a teaching material in lecture materials in universities. The specific target to be achieved in this study is to issue teaching materials in the form of financial accounting books compiled with the Computer Taxation program. To achieve these objectives, this study uses descriptive analysis to identify the problems that exist in financial accounting learning in universities in the city of Medan. That has been running all this time. These problems include not understanding students in using Tax computer programs that have been issued for a long time, and not motivated to study the program because of lack of guidance in carrying out the practice. To find the factors that become obstacles in understanding the use of the program. With the identification of these factors, then a teaching material can be arranged to motivate students to want to like the teaching material and the goal of educating the nation can be achieved.

The aspiration of foreign bodies into the bronchus frequently occurs in children as well as in elderly people. Foreign bodies in the airway not only cause chronic cough and pneumonia, but also result in life-threatening conditions, such as dyspnoea, cyanosis and death. This report presents the clinical characteristics of 9-year-old patient with sub-glottis in the foreign body. The foreign body was dental root canal instrument (reamer).

Abstract: E-sports is digitized sports, the traditional sports venues and equipment transferred to the new carrier, combined with advanced electronics and information technology, sports extends from the real world to the virtual world. From the perspective of e-sports participants, e-sports athletes need higher demands on the physical and mental qualities and embody the spirit of sport information in another society. This paper illustrates the generation of e-sports industry from the perspective of industrial integration and development courses of China’s sports industry. It also expounds China’s current situation and existing problems of the e-sports industry and provides pertinent policy recommendations, which mainly includes relying on strengthening the independent research and development of products; providing financial support to relax market access.

Societies are classified according to their development and use of technology. For most of human history, people lived in preindustrial societies characterized by limited technology and low production of goods. After the Industrial Revolution, many societies based their economies around mechanized labour, leading to greater profits and a trend toward greater social mobility. At the turn of the new millennium, a new type of society emerged. This post-industrial, or information, society is built on digital technology and nonmaterial goods. Educational and instructional supervision occur in a variety of societies; thus the need to explore the various typologies of societies that provide the context for the instructional supervision process.

The main objective of this work was to evaluate the physico-chemical and microbiological qualities of dexamethasone sodium phosphate injection in the city of Douala. The experimental type was conducted from December 2016 to June 2017. It consisted of carrying out tests of physic-chemical and microbiological parameters on 14 batches of injectable DSP, conditioning, pH, TLC identification, dosage of active ingredient, the clarity, nominal volume and sterility of the drug were analyzed. The technics used were a visual inspection, thin layer chromatography, UV/visible spectrophotometry and microbiological technics, were that of direct seeding. The results were compared in each sector (formal and informal) and in both. Thus, it was found that the injectable DSP, which came from the formal sector had a non-compliance rate of 12.7%, while that from the informal sector a non-compliance rate of 39.7%. In both sectors, the injectable DSP had a non-compliance rate of around 26.2%. Both formal and informal circuits were all affected by non-compliance, although there is a predominance in the informal circuit.

The purpose of this study was to assess the influence of procurement practices on performance of construction projects in Tanzania. The principle question to be addressed by this study is „what procurement practices are responsible for performance of construction projects in Tanzania?‟ To answer this question and to achieve the primary objective of this study, the researcher focuses on National Housing Corporation (NHC) as a case study. NHC has been selected for this study because it is one of the major public institutions with a significant portfolio of public projects, some of which have succeeded whereas others have failed. The research design used was descripto-explanatory which allowed a detailed description and analysis of the variables under study; describing and presenting their characteristics and explaining their relationships without manipulation. The target population composed of 60 employees from five different departments within NHC headquarters, of which the researcher conducted a census. The study used questionnaires as the primary research instrument. The data was coded as per the objectives to give distinct differences and multivariate regression done to look at the relationship of the variables. Presentation also was done through their calculated mean, frequency, standard deviation and the correlation analysis of the data collected. The study found that indeed various procurement practices influence performance of construction projects in NHC. The supplier selection was found to reduce conflict of interest between the suppliers and management of the organization and in the process influence productivity of the staff. The study further revealed that that contract monitoring and control reduce risks and triggers off an effort to search for solutions to the identified threats to the project success. The study concluded that to a great extent the performance of construction projects is being influenced by adoption of procurement practices, the study recommended that NHC resources need to be more utilized so as to enable more development and less wastage in the company, NHC should handle on the issue of conflict of interest from the management and the outsiders when dealing with the supplier selection and project implementation section. However, the NHC also need to advance more on the policies regarding the quality of construction projects so as to ensure quality projects are achieved at the long run which is beneficial to the company.