The gastroretentive drug delivery system is site-specific and allows the drug to remain in the stomach for a prolonged period of time so that it can be released in a controlled manner in the gastrointestinal tract. The purpose of the research work is to formulate and optimize the gastro retensive film (GRF) containing Propranolol hydrochloride in order to prolong the release time and improve the bioavailability. Five basic gastroretensive films were developed by solvent casting method for preliminary trial . The best formulation was subjected for two factor two level design approach. Independent variables selected were concentrations of Eudragit S 100 (X1) and Eudrajit RL 100 (X2) and dependent variables were Folding Endurance (Y1) Tensile strength (Y2) Elongation at break (Y3) and in vitro drug release (Y4). The results of the study indicate optimized formulation (P2) exhibit folding endurance 114, tensile strength 1.3 kg mm2, Elongation at break 22% and in vitro release 46.5 % for 12h. The in vitro release data were well fit into Higuchi and Korsmeyer-Peppas model and followed non-Fickian diffusion mechanism. The gastro retensive formulations can be used in diseases where an extended release of propranolol is required.

Poverty is a very complex problem, which is not only limited to economic issues but also related to issues in other fields. State policy (government) is needed in helping solve the problem related to poverty especially in the field of law that is by providing legal protection through the provision of legal aid to the citizens. It is an attempt to fulfill and at the same time be the implementation of a legal state that recognizes and protects and guarantees citizens' human rights on the need for access to justice and equality before the law and fair trial. Islamic values not only regulate the things that are private but also public policies and also constitutional so that the jurists make Islamic law as one of the primary references in establishing positive law in realizing the certainty of law and justice one of them through the fulfillment of the right to legal aid that is part of the legal system of the Pancasila Legal State. Judging from the perspective of dignified justice, the provision of legal aid to the underprivileged is one manifestation of humanizing humanity, that is the manifestation of respect for one's dignity and dignity. The policy of legal aid should be oriented to the legal philosophy of human beings. That is, the law, including the arrangement of legal aid for justice seekers who can not afford, must serve human beings.

Amrutharistam is a vital Ayurvedic formulation used for all kind of fever and rheumatic fever, which is prepared by fermenting the decoction of Tinospora cordifolia containing berberine as one of the active ingredient. Preliminary analysis indicated the presence of berberine being the largest concentration. The HPLC carried out in Lichrospher 100, RP-8e (250*4.6*5) column, mobile phase consisting of phosphate buffer and acetonitrile (70: 30). The determining wavelength was confirmed as 343nm. Five marketed formulations of Amrutharistam A-I, A-II, A-III, A-IV and A-V showed berberine concentration to be 9.63µg/ml, 10.10µg/ml, 10.20µg/ml, 9.64µg/ml and 10µg/ml respectively. The result showed the peak area response is linear within the concentration range of 10-50µg/ml with a correlation coefficient of 0.9998. Recovery studies 50%, 100% and 150% were conducted by standard addition method and found to be 99.804%. The developed and validated method can be effectively applied to the quantitative determination of berberine in Amrutharistam.

The aim of the study was to establish the attitude of students to learning Biology, to examine the academic performance of students in Biology and to compare the attitude of male and female students towards class size. This study investigated the attitude of students to class size and learning Biology. It established the effect of class size on students’ academic performance in Biology in Senior Secondary Schools in Gombi Educational Zone, Adamawa State. The study adopted survey design Three research questions and three hypotheses were postulated. The target population for the study comprised 17, 523 senior public secondary school students in Gombi Educational Zone, Adamawa State, and a sample size of 400 was selected by stratified sampling technique. The research instrument titled “Attitude of Students’ to Class Size and Learning of Biology Questionnaire (ASCSLBQ)” was adapted from Omwirhiren & Faith, 2016. The instrument comprised of 46 items divided into 3 sections. The face and content validity of the instrument was established by two experts in Counselling Psychology and Test and Measurement in the Department of Science Education, Adamawa State University, Mubi. Test-retest method was used to carry out the reliability test and the reliability coefficient was 0.82. The data collected were analyzed using descriptive and inferential statistics which included percentages, mean, Standard Deviation, and Analysis of Variance (ANOVA). The findings revealed that classes are very rowdy because students are too many, making students not hearing the teacher well during lessons, students love Biology as a subject, because they feel at ease in Biology class, feels good when they solve Biology questions, and are willing to spend more time reading Biology books. There is no significant difference between male and female students attitude towards class size. There is significant difference between the male and female students’ attitude towards the learning of Biology; and there is significant difference between male and female students’ academic performance. Biology is a general subject offered by all senior secondary school students, but the classes allocated to them are too small, as a result the classes are overcrowded. Even though the students have keen interest in Biology, they cannot perform practical very well because the teachers cannot give individual attention to the large numbers of students, others cannot even hear him well during lessons because there are no public address systems. This factor could adversely affect students’ academic performance in Biology. Based on this finding it was recommended that number of students in a class should be streamlined to at most 40 students. In addition, government should provide materials for teaching and learning Biology.

This study aimed to determine the quality of Lebanese olive oil by analyzing their chemical composition and their physicochemical characteristics. Olive oil samples were first collected from three different Lebanese areas. Physico-chemical investigation (acidity, peroxide index, specific extinction, total polyphenol content as well as chlorophyll and carotenoid contents) of the samples associated with fatty acid analysis by GC-MS technique and NMR characterization demonstrate the compatibility of samples with the standards of International Olive Oil Council (IOC) norms. However, obtained results showed that olive oil samples exhibited a high oxidation status, revealing the necessity of improving oil extraction procedures as well as its storage conditions. Our results confirmed further that olive crushing; harvesting as well as maturity stages have a great impact on the overall quality of obtained oil.

The article investigates the relationship between possible measures to overcome gender differences and high profile jobs relating to institution policy change and development in selected Universities of Western Uganda. The study adopted an observational, cross-sectional exploration design with both quantitative and qualitative as paradigms in order to describe the data and its characteristics. Questionnaires and an interview guides were employed to gather information from the respondents. Data was analyzed using frequencies, percentages and bar graphs. Study findings showed that there was a positive correlation between addressing gender differences and top job positions in universities in western Uganda. The study suggested remedies like; that there is need to advertise and give scholarships to young and well qualified women to go and pursue further studies for their career development and for helping their organizations to grow. There is need to encourage girl child education through the practice of positive discrimination and affirmative action in society. The study recommend also the practice of gender mainstreaming for all academic institutions to avoid the problem of under representation of both sexes , sensitization of stakeholders for girl child education, encouraging female candidates to apply for higher job positions and addressing gender-imbalance through staff development.

Recently the normal values of pulmonary test parameters [1], level of hemoglobin [2] and glycated hemoglobin [3-5] in Sudanese have been found to be different from the international reference values. The study aimed to compare the values of serum electrolytes (Na+, K+, Ca++) level in Sudanese with the international values. 100 normal healthy adult Sudanese with aged between 18 and 65 years (50 males and 50 females), who were nonsmokers, not Known to be hypertensive or diabetic , have no renal or thyroid problem, living in Khartoum city were included in our study. The data was collected using a structured questionnaire then the levels of Na+, K+ and Ca++ were measured. In the males group the means of Na+ level range was 129-141 mEq\dl, K+ was 3.6- 8.2 mEq\dl while Ca++ had a level range of 7.2- 12.2 mEq \dl. In the females group the means of Na+ level was 134.94 ± 3.86mEq/dl; K+ was 4.34 ± 0.46 mEq/dl while Ca++ had a level of 8.95 ± 0.84 mEq /dl. There are slight difference from the international ranges, yet a further bigger scale study is needed to verify those findings.

Over the past three decades, rapid urban sprawl, a changing economy, and shifting demographics have caused rapid developments, which included the urban regeneration of existing neighborhoods. In the 1940s, after oil and natural gas discoveries in the State of Qatar, Doha experienced massive transformations on social, economic, cultural and environmental levels. These transformations have created (A) the need for creating sustainable neighborhoods and (B) raised questions related to how existing neighborhoods can be more sustainable in the future. This study investigates the neighborhood of Msheireb Downtown Doha and the reasons which have caused its urban regeneration. The study investigates (1) practical forms of sustainable urbanism principles by analyzing the Msheireb project and (2) how this urban project can be enhanced according to these principles. The research design encompasses a summary of the literature, the site analysis, structured interviews and a resultant vision of a sustainable concept for Msheireb to define the actions needed to implement the sustainable neighborhood concept. The findings reveal that, comparing the image of old Msheireb with the current regenerated one, the later neighborhood is compact, pedestrian-friendly and mixed use, which in turn encourage people to engage and promote a higher level of social interaction and therefore, contribute to enhancing the urban livability of the neighborhood.

A study on the contraceptive prevalence amongst married women residing in Bayelsa State was carried out. Its principal objectives was to carry out a random estimate of contraceptive prevalence amongst married women in Bayelsa State, and to determine the contraceptive prevalence, types of contraceptive used and factors affecting the latter amongst women in Bayelsa State. The study was aimed at promoting general public awareness on family planning amongst women in Bayelsa State. A Non-experimental study design on the contraceptive prevalence amongst married women residing in Bayelsa State. A sample random method was employed where only four hundred and ninety eight (498) women within the age range of 15 – 45 years of age were interviewed. Out of the five hundred (500) questionnaires only four hundred and ninety eight (498) were retrieved and used in this study. The highest contraceptive prevalence were between age range of (21-30) (75, 15.7%) highest users based on educational level are Tertiary 142 (28.5%) occupation was business women 99 (19.9%) based on children 1 – 2 surviving children 104 (28.7%). From the result of the research carried out, contraceptive prevalence rate amongst married women in Bayelsa is low when compared to worldwide figure, though higher than the national figure in Nigeria. Education of eligible women on the use of contraceptive should be encouraged.

The main purpose of this study was, to assess the knowledge of nurses regarding pain management at Jinnah Hospital Lahore. A cross sectional descriptive survey was performed to assess the knowledge of pain management among nurses. A convenient sample of n=170 was used to collect the information. The main instrument for Information was a structured questionnaire. A structured questionnaire with demographic variables and causes variables was applied. The data was analyzed on SPSS version 21. The results showed that there is positive response of the respondent mean that nurses know about pain management. The result shows that if there is enough knowledge of the nurses about pain management they will increase patient comfort ability and decrease stress which is due to pain. And suggest that nurses administration must be develop the different strategies to create good strategies to enhance nurses‟ knowledge about pain management.

Mandible is an important and the only movable bone in the craniofacial region. According to the old anatomists, it resembles a u-v shaped blunt bend. The mandible bears teeth, and this horseshoe-shaped/ v- bend bone is attached to many muscles. Understanding anatomy and kinesiology of mandible helps the practitioner/surgeon to choose the best treatment modality and surgical approach.

This paper introduces the application of fuzzy control in system modeling and utilizes the Linear Graph of mechanism modeling method to build the system model, and employs Simulink’s S-function to build the system controller and object to conduct simulation. In this paper, the double-ended component system is taken as an example to describe the linear graph theory commonly used in modeling, and the state space equation and the transfer function of the system are established and simulated based on the linear graph method. In the meantime, this paper also analyzes the merits and demerits of linear graph method and other mechanism modeling methods.

Nasogastric tube feeding (NGT) is used for those patients who can-not sustain their oral requirements. Poor nursing adherence to evidence-based guidelines has negative consequences leading to higher mortality rates, delayed recovery and longer length of stay. Nurses play an intrinsic role in preventing these infections especially aspiration pneumonia by pursuing standard guidelines. Current study was designed to evaluate nurses’ knowledge and practices of NGT feeding in order to reduce complications. Cross-Sectional Descriptive Study design was proposed. Study population included 70 nurses working in three public sector hospitals in Lahore. Nurse’s knowledge was obtained using a self -structured questionnaire and their practices were recorded by direct observation through a checklist. Data was analyzed using SPSS 20. Data was represented in the forms of figures and tables. By knowledge and practice 60% secured under satisfactory level. Nasogastric tube feeding is a critical practice for seriously sick patients and errors in proper knowledge and skills can lead to serious complications. The present study could identify a high level of gaps in knowledge and skills of applying nasogastric tube feeding procedure. This necessitates the action at training institutions for nurses and on job protocols including monitoring for safety of patients.

Renal failure is one of the most increasing issue and patient need to admit or enter in any care organization where care for the renal care or therapy are provided to the patients. The renal kidney failure patient’s kidney stopped working well and it is difficult for the patients to survive easily without dialysis (Weiser 2013). The main purpose of this study was, to assess the level of satisfaction regarding nursing care in dialysis centers LHR. A cross sectional descriptive survey was performed to assess the satisfaction level of dialysis patients. A convenient sample of n=150 was used to collect the information. A structured questionnaire with demographic variables and causes variables was applied. The data was analyzed on SPSS version 21. On the basis of this study results it is concluded that a questionnaire was used for the assessment of patient. It contains multiple questions about nurses and participants. According to these study results it shows that patient satisfaction with dialysis was high. Moreover patients were more satisfied if they provided information about dialysis procedure, nurses also give emotional support to the patient. Finally, questions were asked to the patients about their views on the care provided in the dialysis center. Most of the patients' had satisfied from nurse’s care provided in dialysis center. Patients were more satisfied if they provided information about dialysis procedure; nurses also give emotional support to the patient.

Anacyclus pyrethrum L. root is one among the ingredients of polyherbal formulation frequently employed for the treatment of stress by Ayurvedic practioners. So, the objective of this study was to scientifically validate its use. Animals were administered graded doses of ethanolic extract of Anacyclus pyrethrum root and subjected for anoxia stress tolerance test, swimming endurance test and acetic acid induced writhing test models and its adaptogenic potential was assessed by estimating various parameters. Stressed animals demonstrated altered values of these parameters. Ethanolic extract of Anacyclus pyrethrum root exhibited significant anti-stress activity by restoration of all the altered values. Present findings validate its use in Aurvedic system of medicine.