Excess free-radical formation has been hypothesized to contribute to cancer, atherosclerosis, aging, and exercise-associated muscle damage. Antioxidant supplements such as vitamin C, vitamin E, and beta-carotene have been touted as beneficial for enhancing exercise performance and for preventing certain diseases. Before physicians routinely recommend supplements to prevent exercise-associated damage, more study will be required. Recommendations for the prevention of cardiovascular disease and cancer are more complex. Because study results have been contradictory, individual supplement recommendations must be offered with caution. Physicians must be cognizant of which supplements patients are taking and be prepared to discuss risks and benefits. The most beneficial prescription is probably a daily diet containing five to seven servings of fruits and vegetables..Muscular exercise promotes the production of radicals and other reactive oxygen species in the working muscle. Growing evidence indicates that reactive oxygen species are responsible for exercise-induced protein oxidation and contribute to muscle fatigue. To protect against exercise-induced oxidative injury, muscle cells contain complex endogenous cellular defence mechanisms (enzymatic and non-enzymatic antioxidants) to eliminate reactive oxygen species. Furthermore, exogenous dietary antioxidants interact with endogenous antioxidants to form a cooperative network of cellular antioxidants. Knowledge that exercise-induced oxidant formation can contribute to muscle fatigue has resulted in numerous investigations examining the effects of antioxidant supplementation on human exercise performance. To date, there is limited evidence that dietary supplementation with antioxidants will improve human performance. Furthermore, it is currently unclear whether regular vigorous exercise increases the need for dietary intake of antioxidants. Clearly, additional research that analyses the antioxidant requirements of individual athletes is needed

Project Management in Guinea is growing rapidly such as in many developing countries. It’s heavily used now in diverse area such as in agriculture, construction, manufacturing, telecoms, IT, education, and so on. This high prevalence of making projects in various sectors determined the increasing importance of effective project management. Managing project rightly at a right time with multiple constraints (human and technical aspect) remains the main challenge for project managers. The relationship concerning successful project and the project success factors are topics of great interest in project management. The paper highlights the most Critical Success Factors (CSFs) through project planning, project top management support and stakeholder involvement in project implementation in Guinea.

Staphylococcus aureus is a common bacterium that affects humans and causes several syndromes and infections with fast evolution which can endanger the patient's life. Investigate the incidence of nasal carriers of S. aureus among graduation nursing students who attends to the hospital for at least one year. 122 samples from the nasal cavities were analyzed. The identification of the bacteria was performed by conventional bacteriological methods. The antimicrobial susceptibility tests were performed using the BioMerieux Vitek system in the Bacteriology Laboratory of the Brazilian Army Biology Institute - IBEx. Of the 122 examined students, 51 were carriers of S. aureus, corresponding to a prevalence of 41.8%. The results demonstrated that nursing students who attend the hospital environment are more susceptible to carry S. aureus antibiotic-resistant strains. We suggest periodic medical exams to these students for appropriated antibiotic therapy and adopt precautionary measures in order to avoid the interpersonal transmission of the bacteria in the relationship with health professionals and patients at the hospital environment

Content digitization is a current phenomenon that has had a huge impact on traditional media. The era of globalization has had significant effect on the way media houses the world over strive to reach their audience and especially given that the world is so interconnected to a point that any happening in one continent has a significant effect in the most remote location in another continent. This has led to innovations such as the use of E-Paper that’s geared towards reaching larger audiences by media houses as well as remain competitive in this era of great competition and liberalization of the economy. The purpose of this study was therefore to determine the effect of EPaper subscription on the revenue performance of the Standard Media Group Limited, Nairobi. The study was guided by the Schumpeter’s innovation theory of entrepreneurship. Descriptive survey research design was adopted. Both primary and secondary data were collected. Primary data was collected by the use of a questionnaire while Secondary data sought historical data on the organisational revenues by department and on the profitability of the organisation for the past twentyfive years between 1991 and 2016. The target population included all the 202 members of staff in the Commercial and Online departments at Standard Media Group, Nairobi. The researcher drew a proportional random sample of 30% of the respondents from the two departments who provided the information required. Data was processed and analysed using descriptive and inferential statistics with the help of the Statistical Package for Social Sciences version 22 and Microsoft’s Excel 2013 to generate Frequencies, percentages and regression that were used to answer the research questions. Findings were presented using appropriate tables and graphs that depicted the relationship between the dependent variable and the independent variables. It was established that the rate of revenue growth in the e-paper platform was exponential, and was highly co-related to the overall organizational revenue, and that the combined revenue from the e-paper, and other aspects of digital content provision had exponentially grown from nil in 2009 to over KES 120 million 2016. Further research is suggested on the effect of content digitization on the operational and revenue performance of print media at Standard Media Group, and on the effect of content digitization on revenue performance of the other media houses in Kenya.

Diabetes mellitus (DM) is commonly referred to as a “sugar” and it is the most common endocrine disorder and usually occurs when there is deficiency or absence of insulin or rarely, impairment of insulin activity (insulin resistance). The powdered leaves phoenix dactylifera was extracted with 400ml of 70 % v/v of ethanol and water for 5 hour in soxhelet. Alloxan monohydrate at a dose of 150 mg/kg injected intraperitonally for induction of diabetes mellitus. The extract of Phoenix dactylifera leaves was subjected to anti-diabetic activity in rats. Group-IV & Group-V received the ethanolic & aqueous extract of phoenix dactylifera leaves(500mg/kg) shown a marked reduction in blood glucose level on day 4th i.e. in ethanolic extract it was 284.76±mg/dl while in aqueous extract it was 264.76±6.65. On 10th day of study the glucose level falls up to 264.40±7.72 in ethanolic extract rat & 254.05±9.18 in aqueous extract. The results of the present study indicate that Phoenix dactylifera leaf extract was found to reduce the glucose level in animals made diabetic with alloxan. In the present investigation ethanolic extract of Phoenix dactylifera leaf showed significant anti-diabetic activity

The study was conducted to determine the Etiological basis of dizziness in patients attending ENT clinics in Pakistan. It was a prospective, multicenter, observational, non-interventional, cross - sectional study conducted in five cities across Pakistan, between August, 2014 and March, 2015. The study population included male and female patients attending the outpatient clinics of ENT departments. The patient population was of 18 years of age or older presenting with dizziness. Based on the initial screening patients were diagnosed as vertiginous or non-vertiginous. Patients’ written authorization to use or disclose the patient’s personal or health data was obtained. Benign Paroxysmal Positional Vertigo was the commonest diagnosis (67%) followed by Meniere’s disease (16%) in patients who presented with vertigo attending outpatient departments in ENT Clinics. At baseline visit, 38.3% of the patients were categorized as moderately handicapped. Medication was offered to three quarter of the patient population (69%), while rest of the patients were offered maneuver and medication both (20.8%) and only maneuver (3.5%). DHI was used at the baseline visit and post treatment as well. It was observed in the study that the DHI score was significantly improved in all diagnosis groups after the treatment. At the end of four weeks majority of the patients were categorized mildly handicapped (91.3%). Majority of the patients diagnosed as BPPV were prescribed anti-vertiginous medicines (70%) followed by anti-emetics and pain killers. Amongst the patient reporting with dizziness the commonest diagnosis was Benign Positional Paroxysmal Vertigo followed by Meniere’s disease. Based on pre and post-treatment DHI scores, medication and medication with maneuver helped the patients presenting with dizziness in improvement of Quality of Life.

India is a tropical country where skin diseases like fungal infections, pyoderma, acne, scabies etc. are very common. A large number of dermatological preparations are available in Indian market but studies on the price variation between commonly used topical brands are lacking. Hence the present study was carried out to obtain information on the price variation among different brands of anti-infective, anti-acne & analgesic topical preparations present in India. Information about dosage forms and prices of different brands of commonly used topical preparations was obtained from Current Index of Medical Specialties & Drug Update. Number of brands, percentage price variation, cost ratio etc for various drugs and combinations were calculated. There were total 206 brands manufactured by 52 different pharmaceutical companies of 35 drugs, out of which 24 showed more than 50% cost variation. Largest price variations were seen with mupirocin 2% cream (408.33 %), tazarotene 0.05% gel (183.8%) and diclofenac diethylammonium 1% gel (650 %) in single drug categories & gentamicin 0.1% + clobetasol 0.05% cream (308.82 %) among all fixed dose combinations. Least variation was observed for salicylic acid 2% foam (4.76 %) and terbinafine 1% + ofloxacin 0.75% + ornidazole 2% + clobetasol 0.05% cream (5.69 %). Cost of drugs play a crucial role in treatment outcome by directly influencing the patient compliance. Hence, it is essential to train physicians about cost variations among different brands available in the market so that they can reduce financial burden of patients without compromising the effectiveness of therapy.

The objective of the study was to observe the various clinical features, histopathological and immunofluorescence findings in patients with autoimmune vesiculobullous disorders. The overall M: F ratio of autoimmune vesiculobullous disorders in the study was 1: 1.4. Trunk was the most common site of involvement in all types of autoimmune vesiculobullous disorders. Overall trunk was the most common site of onset of lesions in autoimmune vesiculobullous disorders but in pemphigus vulgaris mucosal onset is more common than trunk and extremities. Incidence of autoimmune vesiculobullous disorder was 0.11% of the total number of patients attending the skin OPD. Pemphigus vulgaris constituted the most common subtype of autoimmune vesiculobullous disorder in this study, followed by pemphigus foliaceus. Pemphigus group of diseases were most common in the 4th decade while bullous pemphigoid was most common in the 7th decade. Histopathological examination showed features typical of each subtype of autoimmune vesiculobullous disorder.

The roles of sex hormones have been under the scope of study for so long by physiologists as well as clinicians. Their actions on the cardiovascular system are undeniable and evidence is growing. Many research investigated the connection between the levels and the protective mechanisms on CVS physiology. It is a popular belief among clinicians that estrogens are powerful protectors of cardiovascular events; but, the notion that testosterone is as well was a novel concept. Testosterone was associated for the longest time with the bad and negative effects on the CVS, such as, increasing the risk for cardiac hypertrophy.

Optimal management sequence for the primary tumor and the liver in synchronous colorectal liver metastases (SCLM) is still controversial. Except reviews, studies comparing the 3 surgical approaches are infrequent. The present study aimed to describe the surgical management of patients operated of SCLM. In particular, we compared short-term outcomes and survival according to the surgical strategy. A multicentric retrospective study was conducted on 125 patients with SCLM. Surgical strategy was defined as classic (colorectal first approach), combined and reverse (liver-first approach). Between 2008 and 2013, 87 patients completed the classic strategy, 24 combined strategy and 14 reverse strategy. The 3 groups were comparable regarding pre-operative data. Liver metastases involvement was significantly higher in reverse group. Severe cumulative postoperative morbidity was 39.2%, similar between the 3 strategies. Ninety-day mortality was higher in combined group (12.5%, p>0.05). Failure rate of liver first approach was 17%. The 3-year overall survival (OS) was 73% in classic group, 78% in combined group and 93% in reverse group. The 3-year disease free survival (DFS) was 29%, 30% and 19% for classic, combined and reverse strategy respectively. There was no significant difference with regard to OS and DFS between 3 groups. We demonstrated that liver first approach is safe and feasible with acceptable perioperative and survival outcomes despite initially worse prognostic criteria. Reverse strategy can be applied to a vast majority of patients independently to the liver tumor burden and should be considered progressively as a reference in the management of SCLM

Dermatoglyphics is the branch of science concerned with the study of prints on the fingers, palm, soles, and feet. This branch of science is an offshoot of anatomical sciences. Dermatoglyphics as an aspect of science has been studied widely by lots of ardent researchers and have been used to solve lots of problems relating to peoples’ identity and ancestry. Although, dermatoglyphics can be studied at three levels (1, 2, and 3) only level 1 (arches, loops, and whorls) have been explored. 99.9% of the works on dermatoglyphics is at level 1 but very few Nigerian indigenous works have been done at level 2 (bifurcations, trifurcations, bridges, ridge ending, enclosures, dots, opposed bifurcations, double bifurcations, island etc). This raises the question, what about level 2 and 3 study? Aim & Objectives: It is possible for one to think that the reason researchers have not dealt extensively on level 2 dermatoglyphics is lack of procedural knowledge and the understanding of the concept. Hence this study was done to explicitly showcase the procedures dermatoglyphics at level 2. Materials and Methods: Data Capture: The use of digital print scanner with very high resolution not less than 9000x4800 dpi (Hp G3110 Scanjet Scanner) which ensures the images are clear and visible. 2)Transfer of Prints: The captured prints are then transferred to a laptop system (computer) via a set of USB cords for examination. 3)Examination of Prints: The prints are assembled into the various categories following the objectives, each print intended to be studied will be zoomed and magnified using the magnification tool in the laptop (computer) for clarity and visibility. I) Make a straight horizontal and vertical line across the print on each finger or toe which divides it into quadrants. II) Examine each quadrant for digital patterns present. Taking note of the morphology of the patterns known. III) Identify and group the patterns seen for each finger or toe. IV) Summation- sum up the patterns for the left and right hands or foot, V) Compute into a statistical tool for analysis. Conclusion: There was marked difference between the males and females in the distribution of the patterns with the females having consistently higher values. Though the females had higher value of the Paul’s Index.

In the past 15 years, awareness concerning natural changes was evidently expanding among population and industries. International agencies and national governments have expanded their endeavors concerning natural resources depletion, ozone depletion, gas emissions and waste reduction. Therefore, the main purpose of this paper is to examine the existing literature on the relationship between just-in-time (JIT), total productive maintenance (TPM), total quality management (TQM) and organisational performance. In total, 20 articles were empirically reviewed, all published in peer-reviewed journals between 2014 and 2018. The articles are analysed in terms of several general variables such as type of research and theoretical viewpoint, and the perspective taken on organisational criteria. The empirical reviewed indicated that JIT, TPM and TQM, maintained by human resource practices, have a significant prospective to develop the organisational performance. However, a simultaneous implementation of JIT, TPM and TQM does not certainly lead to greater performance. As prospective purpose for this, human resources are viewed as restrictive factor both improvement programs draw on. Therefore, this limited resource is acknowledged as vital element with respect to organisational performance when implementing JIT, TPM and TQM concurrently.

Ankylosing spondylitis and rheumatoid arthritis are the most common chronic inflammatory rheumatism. Their localization at the level of the hip stresses severely the functional prognosis. We report a retrospective series of 40 total hip prostheses performed in 32 patients with inflammatory coxitis, collected in the Traumatology and Orthopedics Department at the Mohammed V Military Hospital in Rabat between 2008 and 2016. The average age at the time of the intervention was 42 years with a clear male predominance. All patients were followed in consultation with a clinical and paraclinical examination. Coxitis following ankylosing spondylitis is the most frequently encountered in our series (65.6%). The rating of Postel Merle d'Aubigné was used to assess the functional status of the hip before and after surgery. The total hip prosthesis was cementless in 37 cases and cemented in 03 cases. The clinical results for the 32 patients after a mean follow-up of 04 years were very satisfactory in (88%) of the cases. The objective of this study is to evaluate our functional results and to show the interest of total hip arthroplasty in this type of pathology, in order to improve the quality of life of these often young patients

This research investigates the impact of the global financial crisis on the performance of Nigerian stock market from 2004 to 2013. The main aim of the research was to examine the impact of global financial crisis on the performance of the N.S.E. Data for this research was sourced from a secondary source. The data were statistically analyzed using descriptive analysis and Kruskal-Wallis H test statistical tools. The analysis showed that Global Financial Crisis has no significant effect on Market Capitalization, value and volume of shares traded on the floor of the N.S.E. From the analysis, the researcher concludes that Global Financial Crisis has no significant effect on market capitalization, value of shares traded and the volume of shares traded in Nigerian stock exchange.

The purpose of the study was to find out whether school feeding programme affect retention of learners in primary school education. The study was done in 10 primary schools in Mogotio Division. The unit of analysis constituted of 70 respondents (Head teacher/ Heads of school feeding program, Teachers, parent representatives and pupils). Purposive random sampling was used in this case whereby all the 70 respondents were picked to fill the questionnaire. Descriptive statistics analysis was used whereby the SPSS (Statistical Package for Social Sciences) programme is used. On retention, the study concludes that there were transfer cases in the center. Most parents take their children to private schools citing many reasons, which range from poor performance in public early childhood education centres, poor teaching methods, lack of skilled staff in public centres, and to a little extent due to poor feeding habits in the local primary schools. The findings of this study may be of use to the various primary schools for it would assist them understand better the issues related to school feeding programmes. This would see school managers in the various centres provide learners with balanced feeding programs and create awareness to parents on its importance to proper learning and holistic development of their children. The study would also go a long way to helping the government in making relevant policy to safeguard the wellbeing of primary school learners by providing well balanced feeding programs to these centres as well as budgetary allocation to the same.