This study was designed to investigate the influence of Postate cancer awareness campaigns on the knowledge, attitude and practices of men in SouthEastern Nigeria. The study employed the survey method of enquiry. The population of the study is 8,184,951 adult males in South-Eastern Nigeria. Five research questions guided the study. The data was analysed using Statistical Package for Social Science (SPSS). The result of the data analysed revealed that the awareness and knowledge level on postate cancer is relatively low among the men in South-Eastern Nigeria. Also, most information on postate cancer were made known to the respondents by medical practitioners, however, those respondents that are exposed to the campaigns agreed that the campaigns have influenced their behavior positively. The study recommends that, awareness campaigns should be well structured both in English and the target audience local language to sufficiently and effectively convey the Prostate cancer campaign messages. Thus, the risks and the effects of the negative attitudes of men towards this campaigns must obviously be stated citing relevant examples. Also, campaign planners should involve the target audience/opinion leaders as participants in the campaign and too, lower the age for screening, so that early detection and prevention can be detected before it becomes late. There must always be emotional, physical and psychological appeal in the campaign messages.

The aim of the present study was to increase the solubility and thereby improve the oral bioavailability of Furosemide by incorporating the drug in nanostructured lipid carriers (NLC) and in solid lipid nanoparticle (SLN) and also to compare the efficiency of NLC over SLN. Both the NLC and SLN were prepared by solvent diffusion method using labrafil m 2130 as solid lipid, capryol pgmc as liquid lipid, and tween 80 as surfactant. Properties of Furosemide loaded NLCs & SLNs such as drug content, entrapment efficiency, loading capacity, particle size, PDI , zeta potential, morphology, storage stability, in vitro drug release and mechanism of drug release were investigated and compared. Drug content, entrapment efficiency, loading capacity, average particle size, PDI and zeta potential of Furosemide NLC were found to 83.56%, 75.50%, 25.63%, 99.24nm, 0.302 and -31.2mV and that of Furosemide SLN were found to 84.55%, 71.07%, 24.62%, 193.4nm, 0.835 and -36.1mV respectively. Morphology study by scanning electron microscopy (SEM) analysis showed spherical particles with smooth surfaces. As compared to in-vitro drug release of Furosemide pure drug, both the NLC and SLN showed fast initial release followed by a sustained release, best fitted to Higuchi equation. Pure drug followed Zero order release kinetics. Furosemide NLC showed higher entrapment efficiency, drug loading capacity, in-vitro drug release, reduced the drug expulsion in storage when compared to SLN. This investigation demonstrated the efficiency of NLC over SLN for improved oral bioavailability of Furosemide and it was deduced that the liquid lipid (capryol pgmc)was the principal formulation factor responsible for the improvement in characteristics and pharmacokinetics of NLCs.

Language teachers in India continue to struggle with effective development and successful implementation of a task-based lesson. The current paper presents a template for teachers to frame and execute language tasks to achieve desired outcomes. The paper begins with a brief discussion of tasks, and then follows a discussion on three-tier task-based learning framework, model and lesson. A teaching unit/ sample lesson is also included to illustrate the method. The sample lesson presented was developed for elementary stage students studying in schools of India. The developed plan focused on vocabulary and structures needed to make reservations in different paid establishments. Any task-based lesson primarily includes pedagogical tasks that mirror the real-world tasks. Owing to its usability outside the boundaries of the classroom, a task-based lesson becomes more meaningful and apropos to students. Such basic lesson can be used as a model to teach relevant vocabulary and sentence structures pertaining to other real world tasks including talking about clothes and fashion, calling customer care for help, other telephonic conversations etc.

Postoperative period is very crucial from recovery point of view. For fast and smooth recovery, postoperative period should be free of complications especially pain. It became more important in case of ceaserean section as patient also has to look after her baby. Cautious use of analgesic drugs has to be made in postoperative ceaserean section patient as they can adversely affect health of the baby also. Intraperitoneal instillation of ropivacaine is effective analgesic and has lesser side effects than pharmacological drugs. Our hypothesis is that intraperitoneal instillation of ropivacaine reduces postoperative pain in patients undergoing ceaserean section. This randomized control study was conducted on 60 patients of ASA grade 1 and 2 after taking ethics committee approval. Group I (n=30) is control group with no local infiltration and Group II (n=30) Local infiltration of 15 ml at incision site and intraperitoneal instillation of 5ml Inj. Ropivacaine 0.2%. Diastolic, systolic and mean blood pressure, heart rate were measured throughout the procedure. Time of rescue analgesia and VAS score was recorded postoperatively. Intraperitoneal instillation of 0.2% ropivacaine provides postoperative analgesia. Mean duration of rescue analgesia in group I was 115.67±4.09 that was significant (p<0.05) in comparison to group II 170.33±3.69. intraperitoneal instillation of 0.2% ropivacaine reduces postoperative pain in patients of ceaserean section under spinal anaesthesia.

Higher education is not a form of cost but is one form of investment. This form of return can be in the form of a high bargaining value when the relevant person gets a job offer. Higher education not only has economic value in individuals, but in society One of the economic values of higher education is the existence of employment opportunities for the community when higher education is held in a location where economic value can be in the form of employee recruitment or the opening of new jobs in the informal sector for the surrounding community. The challenge for the education sector is to develop educational systems capable of improving basic education equity, education quality and relevance of education to development needs, as well as science and technology education. Because everything that has been proven to have direct and indirect impact on economic growth of the Indonesia Economic.This study uses a qualitative approach with study methods case. The data analyzed is the result of interviews with the field of service and direct observation in the field of services and general fields, and review documents at Private Universities in Surabaya

Extended-spectrum – beta lactamases (ESBLs) are increasingly detected globally among Escherichia coli (E.Coli) and Klebsiella pneumoniae (K.pneumoniae). This study was designed to determine the prevalence and antibiogram of ESBLs produced by E.coli and K.pneumoniae clinical isolates obtained from various clinical specimens through different hospitals in Khartoum state -Sudan. An analytical comparative cross-sectional study was conducted. Identification of the isolates was done by using conventional biochemical methods ESBL screening, confirmatory according to CLSI guidelines. Statistical analysis was performed using the Statistical Package of Social Sciences (SPSS). Total of 368 isolates of Escherichia coli(n=216) and Klebsiella pneumonia (n=152) isolates were processed , Overall ESBL phenotype prevalence was 36.7 %, 40.1% and 34.2% of K. Pneumoniae and E. coli isolates respectively were confirmed to be ESBL phenotype. In this study, meropenem and imipenem were the most active antimicrobial agents against them. This study was indicated high prevalence of ESBL phenotype in Khartoum-state, with multidrug resistant trend, there is a need for longitudinal and nationwide surveillance as this help in tracking antibiotic resistant and regulating antibiotic policy.

This study aims to analyze the behavior of the use of Information Systems in registered taxpayers at the Palembang Middle Tax Service Office through the Unified Theory of Acceptance and Use of Technology. Specifically the purpose of this study was to examine trust in government, hedonic motivation, and social influence on the Behavior Intention and User Behavior of e-faktur and test Behavior Intentions towards User Behavior of e-faktur. This research is Quantitative Descriptive Research. The sampling method is proportional stratified random sampling method. The number of samples was 282 respondents are director and accounting major in company who registered in Middle Tax Service Office Palembang. The method in this study is statistics using SmartPLS 3.0. The results of this study indicate that trust in government has a significant effect on Behavior Intention whereas behavior does not have an effect as well as Hedonic Motivation which has a significant positive effect on behavioral intentions while behavior does not affect. Social Influence does not have a significant effect on the Behavior Intention and User Behavior of e-faktur. As well as Variable Intentions of Behavior towards User Behavior e-faktur has a significant effect. In the next study we suggested adding gender, age, experience and voluntary variables.

Diabetes is a chronic condition that occurs extremely due to a combination of sedentary lifestyle and following an imbalanced diet. Thus the medications are to be taken for life time. So there is a need for the prescribers to prescribe the medication which would be cost effective to the patients. This study was planned to analyse cost variations of antidiabetic drugs available in Indian market. There is a wide range of variations as the price of drug marketing in India. This paper gives the information regarding the drugs available for diabetes, their available brands, average cost and cost variations. Which help the physician in giving the drugs to the respective patient which are effective to them as well as which are cost efficient and are afforded easily by the patient. As a result of which there will less medication non-adherence and increased patient compliance. It was conducted by taking the maximum and minimum cost of anti- diabetic agents manufactured by different brands of same drug, strength and dosage forms. The data is obtained from the current index of medical specialties [CIMS] April-July 2018. The cost ratio and percentage cost variations were calculated for each anti-diabetic drug. The average percentage price variation of different brands of the same oral anti-diabetic drugs in Indian market is very wide.

Abstract: The objective of this study is to explain the importance of use of AFOs and exercise in children with toe walking due to calf muscle tightness, to provide advance rehabilitation techniques that can reduce the effects of progressive contractures, postural deformities and imbalance and to explain the best treatment and guidelines to parents to make the child maximum independent. This is an experimental based study in which participants are randomly selected. Fifty male and female participants (children) of age between 03 yrs –12 yrs are selected who presents with toe walking due to tightness in Achilles tendon. All participants are assessed prior to treatment and then reassessed after three month of therapy. Data was collected through an assessment form. Data was analyzed by the paired T-test statistics .The result shows a significant difference (p=0.00) in the variables of cadence, pain (VAS), ankle dorsiflexion & planter flexion range (p<0.005).The mean result for pre and post cadence is (-5.820), post treatment cadence improved because of achieving improved ankle dorsiflexion range. The study demonstrated that use of AFOS and exercises can achieve good ankle function and range of motion can be improved .The study shows that children with Toe walking due to Achilles tendon tightness can improve their walking pattern and ADLs by the use of AFOS & exercises.

А device for the isolation of nucleotide complex from biomass of Saccharomyces cerevisiae cells was developed, and the biological active substances in the extract were analyzed. The isolated nucleotide preparation can be used to stop oxidative stress and improve immunity. The developed device allows extraction of biologically active substances from Saccharomyces cerevisiae cells in series by extractants: distilled water under the action of an alternating voltage with a frequency of 105 Hz, a solution of hydrochloric acid with pH = 1.0-1.5 without using voltage. After acid extraction, the extract was neutralized with sodium hydroxide solution. The extracts obtained were combined and dried. The technical result of the device is a more complete two-fold extraction of the nucleotide complex from native Saccharomyces cerevisiae biomass. The use of our constructed device makes extraction of biologically active substances easier and complete. The content of biologically active substances, such as adenine nucleotides, amino acids, vitamins, micro-, macro- elements in the obtained extract was analyzed. A comparison of the activating effect of the isolated nucleotide preparation on Ca2+-dependent NO - synthase with T-activin was performed. Experiments showed that the nucleotide preparation, obtained by new device has a pronounced activating effect on Ca2+ -dependent NOS from rat thymocytes.

Poverty is a serious issue which is faced by masses around the world. This study aims to determine whether the microfinance institutions established for the purpose of reduction of poverty have been successful in achieving their objective or not. Primary data was collected for the proposed research study through structured questionnaires. In order to analyze the collected data multiple liner regression and paired t-test were applied. Outcomes illustration that microfinance has a durable positive effect on children education and enterprise financial performance. Though, there is varied indication found on food security, household expenses and household assets. No effect has been detected on housing and income smoothening of enterprise. Among other independent variables, it was exposed that number of salaried persons was originate to be very important variable contributing to the wellbeing of the microfinance clients

Smooth and complication free postoperative period is always desired after completion of surgery in every case but it becomes more important in case in ceaserean section as patient has to start nurture newborn immediately. All the techniques for multimodal analgesia have some or other side effects and thus they have to be used very cautiously in postoperative ceaserean section patient as they can adversely affect health of the baby also. Local infiltration of ropivacaine is effective analgesic and wit lesser side effects than pharmacological drugs. Our hypothesis is that local ropivacaine infiltration reduces postoperative pain in patients undergoing ceaserean section. This randomized control study was conducted on 60 patients of ASA grade 1 and 2 after taking ethics committee approval. Group I (n=30) is control group with no local infiltration and Group II (n=30) local infiltration of 20 ml Inj. Ropivacaine 0.2% at incision site. Diastolic, systolic and mean blood pressure, heart rate were measured throughout the procedure. Time of rescue analgesia and VAS score was recorded postoperatively. local infiltration of 0.2% ropivacaine provides postoperative analgesia. Mean duration of rescue analgesia in group I was 115.67±4.09 that was significant (p<0.05) in comparison to group II 147.17±4.67. local infiltration of 0.2% ropivacaine reduces postoperative pain in patients of ceaserean section under spinal anaesthesia.

China’s foreign exchange reserves kept growing quickly for a decade; however, they have decreased since 2014. The paper aims to test for a break date probably existing on the trend function of foreign exchange reserve series. Monthly series covered the period from January 2000 to March 2018. A standard ADF unit root test, an ERS DF-GLS test along with the modified AIC, and an MZα test along with GLS detrending were conducted. Structural shift tests were the Perron test (in a mixed IO Model C and Model A or crash model), and the Zivot-Andrews test (in a mixed IO Model C and Model A). Empirical analyses show that at least two unit roots exist in the variable, implying a robust long memory. A break point took place most likely in January 2014. US exit out of quantitative easing (QE) and federal funds interest rate hikes may be (at least partially) attributable to the shift.

Postoperative pain in patient undergoing open prostectomy is quite uncomfortable for the patient. All the techniques for multimodal analgesia has some or the other side effects. Transversus abdominis plane (TAP) block is newer, effective and comparatively simpler to perform and provides better and denser pain relief than pharmacological agents. This randomized control study was conducted on 60 male patients of ASA grade 1 and 2 undergoing open prostectomy after taking ethics committee approval. In group R (n = 30), 0.25% Ropivacaine hydrochloride (20ml) and in group S (n=30), 20 ml of normal saline was given through TAP block after completion of surgery. Time of first rescue analgesia and total dose of analgesic consumption for 24 hour postoperatively along with pain visual analogue scale (VAS) were measured and compared along with other vitals like heart rate, SBP, DBP and MAP. Postoperative TAP block using ropivacaine just after completion of surgery results in better analgesia in post-operative period in patients undergoing open prostectomy. Time of rescue analgesia in group R was 158.5±42.08 and in group S was 68.6±98.8. Also total analgesic consumption and VAS score in postoperative period was significantly low in ropivacaine group when compared with the saline or control group (p<0.05). TAP block using roipvacaine 0.25% in open prostectomy patients provide better analgesia in postoperative period and reduces amount of total analgesic consumption and thus the side effects associated with the later.

This paper examined the effect of pension industry investment on financial intermediation in Nigeria. The study used Ex-post facto research design. Its specific objectives were to examine the effect of Pension fund investment in Federal government bonds, Pension fund investment in State government bonds and Pension fund investment in Private sector bonds on financial intermediation in Nigeria. Ordinary Least Square regression was used as analysis technique. It was found that Pension fund investment in Federal government bonds has positive and no significant effect on financial intermediation in Nigeria; Pension fund investment in State government bonds has negative and no significant effect on financial intermediation in Nigeria; and Pension fund investment in Private sector bonds has positive and no significant effect on financial intermediation in Nigeria. This implies that a unit change in pension fund investment do not lead to significant increase in financial intermediation. Based on the findings of the study it was concluded that pension industry investments have insignificant effect on depth and liquidity of financial intermediation in Nigeria. It was recommended that the pension industry should spread its investments beyond financial instruments in order to widen its investments portfolio and aid a larger sphere of the economy with its intermediation.