This study aims to analyze the performance of PT Garuda Indonesia (Persero), Tbk Period of 2011-2017 due to the phenomenon of its stock price decreasing relative to the IPO price. Analysis of this study using the variables Current Ratio (CR), Debt to Equity Ratio (DER), Total Asset Turn Over (TATO), Return On Equity (ROE), Price Earning Ratio (PER), Market Value Added (MVA), and Company Size (Size). Based on the analysis, only the DER and MVA variables have a significant, the other variables have not significant. Where DER has negative effect and MVA has a positive effect on stock prices. R2 value of 0.7436 means 74.36% of the stock price is influenced by CR, DER, TATO, ROE, PER, MVA, and Size, while 25.64% is influenced by other factors. The results of the DER analysis is states that the greater the debt, the higher the risk that the company will bear. The results of MVA analysis is states that investors will be attracted to companies that have good MVA values. To increase stock prices, it is recommended that the GIAA need to reduce debt levels and increase MVA.

Oxidative stress is the outcome of an imbalance between the production and neutralization of reactive oxygen and nitrogen species (RONS) such that the antioxidant capacity of cell is overwhelmed. The present review briefly summarized the underlying role of overwhelming levels of RONS in the pathophysiology of diabetes mellitus (DM). The primary causative factor of oxidative stress in DM is hyperglycemia, which operates via several mechanisms. However, the individual contribution of other intermediary factors to hyperoxidative stress remains undefined, in terms of the dose response relationship between hyperglycemia and overall oxidative stress in DM. Intuitively, the inhibition and/or scavenging of intracellular free radical formation provide a therapeutic strategy to prevent oxidative stress and ensuing pathologic conditions.

This study aims to analyze the effect of JKN mobile services on brand image and satisfaction of JKN participants, brand image on satisfaction of JKN participants, and analyze the effect of JKN mobile services through brand image as an intervening variable towards satisfaction of JKN participants. The population in this study were all participants in the Jambi City Branch Health Social Security Organizing Agency which were as many as 563,806 people. The sample size refers to Slovin theory with an e value = 10%, so that a sample of 100 participants was obtained. The collection method uses a survey, followed by a statistical method to test the hypothesis that is by path analysis. The results of this study indicate that JKN mobile services have a positive and significant influence on brand image and satisfaction of JKN participants, as well as brand image has a positive and significant influence on satisfaction of JKN participants. Besides that JKN mobile services through brand image also have an influence on the satisfaction of JKN participants.

North Sumatra has the potential of tourism from the physical aspect (natural beauty) and non-physical (history, customs and regional specialities). The purpose of this study is to analyze and evaluate the components of product and tourism promotion which has a significant effect on the decreasing of tourists in Lake Toba Area and designing the necessary policy and strategy to be implemented to overcome the decreasing tourist in Lake Toba Region. This study is quantitative research, where the research area covers seven tourist districts in North Sumatra by using 150 tourists as samples. The research finds that tourism products do not have an effect on the interest of visiting directly but it affects the tourist image. Promotions affect visitor interest both directly and indirectly through destination images. In the meantime, the regency needs improvements to the tourist attractions of the North Tapanuli Regency

Background: The aim of this study is to identify the profile of patients being referred for cytogenetic analysis in the medical genetics and oncogenetics unit of FEZ Hassan II University Hospital, to determine the prevalence and type of chromosomal abnormalities in the different groups and to compare the results with those of similar studies done in other countries. Materials and Methods: We examined the analysis of 1,200 cases referred to the medical genetics and oncogenetics unit of FEZ, between September 2009 and June 2014. They were grouped according to the indications of the cytogenetic study. Frequencies of the different numerical and structural abnormalities were calculated. The relative frequency of cases with abnormal karyotypes was also determined in each group. Results and Discussion: 70,4% cases were referred from pediatric department and 54,4% are aged under 5 years old. Cytogenetic testing was essentially requested for Dysmorphism (25,6%), Mental Retardation (16%), Down syndrome (14%), girls’ growth retardation (13,8%) and for recurrent miscarriage (12,6%). Of the 1200 cases studied, 79% had a normal karyotype and 21% had chromosomal abnormalities. The most common chromosomal abnormality was trisomy 21 (11,7%) followed by Turner syndrome (2,1%) and Klinefelter syndrome (1,5%). Conclusion: This study compares the results of cytogenetic analysis of chromosomal abnormalities in the north Moroccan population with other studies and research centers. This comparison will help Moroccan clinicians to determine the priority for requesting a cytogenetic analysis in individual cases.

Objective: This preliminary study aims (1) at validating the use of Acute Physiology and Chronic Health Evaluation II (APACHE II) scoring system in cardiac patients admitted to the intensive cardiac care unit (ICCU) for prediction of the risk for mortality, (2) to evaluate the use of a modified APACHE II (mAPACHE II) with addition of the scores related to urinary levels of oxidative stress parameters in prediction of the risk for mortality. Design: Hospital based prospective study. Setting: Tertiary care hospital in South India. Methods: Cardiac patients (n=100) admitted to the intensive cardiac care unit between the age of 18-77 years were enrolled. APACHE II score was calculated. The predicted mortality was calculated on the basis of this score. Urinary malondialdehyde (MDA) and ceruloplasmin (Cp) levels were analyzed and mAPACHE II was calculated. Results: The mean APACHE score was 11 ± 4.14. The ICCU mortality rate within 24 hours after admission was 8%. The area under the receiver operating curve (ROC) for APACHE II score was found to be 0.8 indicating good discrimination and for mAPACHE II score was 0.7 indicating moderate discrimination. Conclusion: APACHE II scoring system has a good discrimination when applied to cardiac patients. However, mAPACHE II also shows moderate discrimination when applied to these patients.

Various tension headaches are produce by emotional stress, fatigue, or problems connecting the joints or muscles of the jaw or neck. 1.002 And 1.030 is the ideal specific gravity of urine. Specific gravity outcome over 1.010 can show little dehydration. The upper the quantity, the further dehydrated you possibly will be. The urine indicative reagent band test use for the specific gravity of urine. In this study we concluded that specific gravity of urine is not related to the headache in tension. Because p ≥ 0.1 this is not a significant result.

Bureaucratic reform and institutional transformation of the Ministry of Finance continues to date which necessitates a fundamental change in civil service performance paradigm. One of them is towards professionalism in order to realize a reliable and trusted organization in society. In order to achieve the result, it is necessary to have the ability and expertise or competence in managing each job. The present study aims to analyze how the influence of competence, education and training either partially and simultaneously on employee performance. The type of research undertaken was a correlational study at the state Assets and auction services office, Medan. The primary data source used questionnaire instrument with respondent as much as 85 people. Data analysis using multiple linear regression analysis aimed to prove the influence of independent variables (X) on the dependent variable (Y). The result of this research shows that competence and education and training either partially or simultaneously have a positive and significant effect on employee performance. Thus through the leadership of the organization, it is recommended that employees actively and continuously improve the competence of each employee. Then provide an equal and comprehensive opportunity for every employee to follow education and training in order to create or acquire new types of competence. The goal is that the work of each organization line allows for easy, fast and quality work

The intention of present study was to evaluate any relation between nitrite in urine and watching horror movies. Over-all 100 subjects participated in this project. Nitrates and nitrites are the nitrogen comprising compounds. The variance is only in their structures. They are existing naturally in some vegetables, for example, green vegetable, celery and cabbage. The urine containing nitrates is considered as normal but existence of nitrites leads to urinary tract infection (UTI). Injurious bacteria live in kidneys, ureters, bladder and urethra. They induce nitrates into nitrites by the support of their enzymes. These are the cause of nitrites in urine that is perilous medical condition. The symptoms usually confronted during this problem are cloudy urine, smelling urine, blood in the urine, burning urination and increased urgency of urination. As we consider horror movies, the first thing that derives to mind is horror, fear or terror. Such movies even can congeal your blood. The impact of horror movies depends upon the person. Some people take pleasure watching these movies and some feel uncomfortable. But mostly people are ignorant about the effects of such scary movies. Some theories depict the positive impacts of such films and some make known their negative prospects. It was determined from the present study that watching horror movies had not really influenced people for having nitrites in their urine. A very few exhibited the positive results of nitrites in the urine which exposed non-significant relation between urine nitrites and watching horror movies.

Organizational citizenship behaviour (OCB) is a willingness to play an extra role regardless of whether or ungiven a formal award. This study aims to analyze how the influence of employees’ job satisfaction, organizational commitment, employees’ working period, and perceived quality relationship quality on OCB employees in PT KPPN. Formulating effective policies to address issues related to the still low OCB employees at PT KPPN. The independent variables in this study are employees’ job satisfaction, organizational commitment, employees’ working period, and perceived quality relationship quality. The dependent variable of this research is organizational citizenship behaviour (OCB). The subject of this research was 34 employees at PT KPPN. This study uses questionnaires in data gathering, whereas hypothesis testing uses F-test and t-test. The hypothesis analysis concluded that work satisfaction and organizational commitment have significant influence over OCB. These results show that the higher the job satisfaction and organizational commitment of an employee, it will increase the employee's OCB

The study aimed to show effectiveness of teaching Social and National Education subject using the flipped class strategy in improving Academic Achievement Among the fifth primary grade students in both Taibeh and Westieh Brigades in Irbid Governorate, through comparing it to the ordinary method in teaching. The study sample consisted of (50) male students of the fifth primary grade in Kufr Asad Primary School distributed into two sections who were chosen by the intentionally method. The random assigning was used to distribute the study individuals into two groups; the experimental group which consisted of (25) students taught using the flipped class, and the control group which consisted of (25) students taught by the ordinary method. To achieve the study objectives, the researcher prepared three videos for the lessons of the unit of Economic resources in The Hashemite Kingdom of Jordan of the Social and National Education subject for the fifth primary grade based on the flipped class strategy, in addition to an academic achievement test was also prepared. The study results revealed that there were statistically significant differences at the level of (=0.05) between means of the experimental and control groups students’ degrees in the achievement post-test due to the variable of teaching strategy (flipped class) and for experimental group students. The study concluded a set of recommendations, the most important of which are: hold training courses for teachers and supervisors about employing the flipped class strategy in teaching and employment of modern techniques and social media in the educational process.

The relationship between color psychology and consumer behavior is at the centre of most marketing activities in the business environment. Empirical and theoretical literature asserts that color psychology is instrumental in determining the effectiveness of marketing activities, particularly when properly integrated in the organization’s manufacturing and distribution strategies. There are different interpretations of color as determined by consumers’ beliefs, culture, and attitudes. The purpose of this research is to investigate the relationship between color psychology and consumer buying behavior within the apparel market. The apparel market was chosen due its distinctive cultural dynamics and consumer psychological beliefs compared to other markets. There has been an increase in consumer buying behavior variations across the globe as a result of varying interpretations of marketing mix elements. The article submits that color psychology is one of the main features that determine consumer behavior in the apparel market. Data was collected through secondary sources such as journals, articles, and empirical sources such as existing researches regarding color psychology, consumer behavior regarding product color, and cultural perceptions on color within the apparel industry. Color psychology plays a bigger role in effecting emotional and intellectual influence among consumers. Color perception and color psychology affects people’s behavior in such a way that the symbolism of the colors resonates with people’s perceptions, hence linking it with information from their cultures. Through the color perception of different cultures, the research concluded that using a color that is associated with something negative will negatively affect the customers’ retrieval cues, therefore repelling them from purchasing the product or service.

The general objective was to evaluate the in vitro activity on Salmonella enterica of typhi stereotype of plant drugs used in the treatment of typhoid fever. The crop drugs harvested were processed and dried for three weeks. After maceration in ethanol, the crude extracts were concentrated using a rotary evaporator and a phytochemical screening was carried out. The antimicrobial activity of the ethanolic extracts was evaluated in vitro on Salmonella enterica of typhi stereotype, by the method of microdilution in liquid medium on microplates of 96 wells in U bottom. Seven possibilities were offered for this evaluation in the microplates: three first (E1, E2 and E3) concerned the isolated extracts and the four others (E1 + E2 + E3, E1 + E2, E1 + E3 and E2 + E3) combinated extracts. The observation of the turbidity of the microplate liquid media after 24 h of incubation allowed the determination of the minimal inhibitory concentrations (CMI) and the seeding of the wells on solid media HEKTOEN and EM allowed the determination of the minimal bactericid concentrations (CMB). Characterization of the different groups of secondary metabolites in isolated ethanolic extracts revealed the presence of phenols, steroids, triterpenes, coumarins and alkaloids. Isolated extract of Costus afer showed a very low CMI and CMB with values of 0.07 and 0.15 mg/mL and was more active on Salmonella enteric typhi stereotype than the other two isolated extracts. Combination of Costus afer and Annickia chlorantha (E1 + E3) stems showed low CMI and CMB with values of 0.15 mg/mL and were more active on S. enterica of typhi stereotype. The combinated extracts showed CMB values between 0.15 and 0.60 mg/mL versus 0.15 and 1.25 mg/mL for the isolated extracts. Analysis of CMI and CMB has shown that combinated extracts have more effective antibacterial activities than isolated extracts because of the positive interactions between bioactive contents involved, and should be considered in in vivo pharmacological activities in rats.

Objective : This study aims at (1) validating the use of Acute Physiology and Chronic Health Evaluation II (APACHE II) scoring system in the medical intensive care unit ( MICU) for prediction of the risk for mortality, (2) to compare the predicted death rate with the observed death rate of the patients gender wise and age wise. Design: Hospital based prospective study. Setting: Hospitals in South India, affiliated to medical colleges. Methods: A total of 350 patients admitted in the MICU between the age of 18-57 were enrolled for this study. APACHE II score was calculated in each patient on the day of admission within 24 hours. The predicted mortality was calculated on the basis of this score. Results: The mean APACHE II score was 9.42 ± 3.4. The ICU mortality rate within 24 hours after admission was 14%. The area under the Receiver operating characteristic curve (ROC curve) was 0.8 indicating good discrimination. The standardized mortality ratio (SMR) was 0.9. Conclusion: The study validates that APACHE II can be a reliable tool in predicting the mortality rate in MICU patients of Indian population within 24 hours of their admission.

Ascorbic acid (vitamin C) is a water-soluble micronutrient required for multiple biological functions. Ascorbic acid has been found to have a long history of use in traditional systems with antioxidant effects that can control the generation of free radicals. Free radical level was reported to be high in cancer cells. The objective of this study was to observe the effects of ascorbic acid (40mg/kg/BW/day for 12 weeks) on hematological and thiobarbituric acid-reactive substances in adult male rabbits. The effects of ascorbic acid on total erythrocyte counts (RBC), hemoglobin (Hb), packed cell volume (PCV), total leukocyte counts (WBC), mean cell volume (MCV), mean cell hemoglobin (MCH), mean cell hemoglobin concentration (MCHC), plasma glutathione-S-transferease (GST), acetylcholinesterase (AChE) and thiobarbituric acidreactive substances (TBARS) at end of 12-week of treatment. Treatment with Ascorbic acid caused significant (P<0.05) increase in RBC and WBC, while did not cause any changes in Hb, PCV, MCV, MCH, MCHC, the activity of GSH and AChE compared to control. (TBARS) was significantly (P<0.05) decreased compared with control group. The study concludes that adding a Vitamin C source with a meal can improve anemia situation and reduce free radicals in adult male rabbits over an extended period of time