Histiocytic Sarcoma (HS) is an extremely rare tumor with aggressive course and arises in lymph nodes and extra nodal sites. We present a case of HS in a 97-year-old male patient with non-specific clinical features. CT scan revealed left axillary lymph node enlargement and a hypo dense lesion in spleen. On Lymph node biopsy, a diagnosis of HS was made based on the histomorphology and immunopositivity of tumor cells for CD68 and CD 163. Negative markers ruled out the other mimics. Considering his age of 97 years, he was not considered to be suitable for surgery or aggressive therapy. HS is an extremely rare neoplasm and it is a diagnosis of exclusion. The key to diagnosis is immunohistochemistry. Molecular genetic studies have reported a few abnormalities and needs to be confirmed.There is no standard protocol for the management of HS due to its rarity.

Infertility, one of the most common disorders confronting gynecologists, has multifactorial etiology. Infertility is a public health problem during the re¬productive age, affecting about 10-15% of couples attempting to achieve pregnancy in worldwide. Infertility is defined as a condition of the reproductive system in which there is a failure to achieve clinical pregnancy after 12 months of regular unprotected sexual intercourse. Study was conducted and the various causes diagnosed in the eligible couples with history of infertility based on clinical examination, Investigations and procedures like hysteroscopy and diagnostic laparoscopy, second aim is to determine the outcome of these studies after intervention carried out in infertile couples. Study was performed in tertiary care centre over a period of 1 year from June 2018 to July 2019, infertile couple with primary and secondary infertility aged between 20 and 45 years were included in the study. In present study 40 infertile patients were evaluated. On detail investigation it was found that causes of infertility were PCOD, multiple adhesions, Fallopian tube adhesions, TO mass, hydrosalpinx, uterine anomaly, Fibroid , blocked fallopian tube. Patients were given treatment like myomectomy, PCO drilling, antibiotics, adhesiolysis septal resection, AKT, ovulation induction depending upon cause of infertility. 10 patients conceived, 10 patients didn’t conceive after taking treatment.5 patients left the study in between and 15 patients didn’t came for followup. Detail evaluation of infertile patient should be done to diagnose cause of infertility. There are many common causes of infertility in females which should be evaluated and given treatment. Patient should be explained significance of follow up to have good outcome of infertility treatment

This study aims to examine and analyze the effect of perceived usefulness and security on consumer trust towards repurchases intention in online travel agent industry. Research data is primary data derived from online questionnaires sent to consumers which at least had done transaction in Tiket.com Online travel agent. Sampling numbers in this research are 132 respondents and the analysis method used is SEM (Structural Equation Modelling) with AMOS 24 Software. The result reveals trust is able to mediate perceived usefulness and security with repurchase intention in online travel agent industry. Implications and limitations are discussed.

Septic arthritis presents with pain and swelling in the joint, and if untreated cases can lead to irreversible arthropathy and disability is an unusual complication during pregnancy and post-partum period. The morbidity is due to destruction of the articular cartilage resulting in impaired mobility of the joint. Severity depends upon the organism involved and host's own defences. Septic arthritis of the knee joint is very rare during post-partum period and very few cases have been reported so far. We report a rare case of post-partum Staphylococcal septic arthritis of the knee joint in a low risk woman, who was successfully treated

This study aims to examine and analyze the effect of satisfaction and e-service quality on consumer trust towards repurchase intention in e-commerce industry. Research data is primary data derived from online questionnaires sent to consumers which at least had done transaction in Lazada E-commerce. Sampling numbers in this research are 180 respondents and the analysis method used is SEM (Structural Equation Modelling) with AMOS 24 Software. Trust is able to mediate satisfaction and e-service quality with repurchase intention in e-commerce industry. Repurchase intentions is key value of e-commerce success. The study provide evidence that trust can is built through customer satisfaction and e-service quality.

Neonatal hypothermia recognized as an important contributing factor to neonatal morbidity, and has been associated with mortality risk in newborns and young infants (1, 2). This study aimed to assess nurse’s knowledge and practice regarding neonatal hypothermia in Khartoum state hospitals.

In this paper an attempt is made to analyze and outline the legislative framework regulating the selection of school principals in primary and secondary education since 2002. The aim of this study is to accurately depict the laws restricting the selection of school principals, so as to feature problems and difficulties, and point out the obstacles in selecting and employing them on a merit-based system, with the goal and wish to focus on achievements and on an effective performance in their administrative and pedagogical role.

The purpose of this study was to examine the effect of brand trust in mediating online consumer behavior and customer satisfaction with repurchase intention in online store owned by offline retailers. Two hundred and sixty respondents of consumers aged 15 to 24 (generation z) participated in this study both women and men. These respondents are consumers who have shopped both offline and online in Hypermart retail. Respondents were asked to answer questionnaires regarding their opinions about the behavior of internet usage, satisfaction and trust of the retail. The results obtained were analyzed by SEM (structural equation modeling. Offline brand trust is able to mediate online consumer behavior and customer satisfaction with repurchase intention in online stores owned by offline retail stores. This research emphasizes the trust of the brands owned by retail stores where the main business is selling products offline. While on the other hand there have been many e-commerce and online stores that were earlier in starting sales online. Based on this, it can be seen how offline brand trust is able to play an important role in attracting consumer buying intention in the new (online store) business format owned by the offline retailer

Aims: The present study aimed to formulate herbal gel preparations containing alcoholic extracts of Withania somnifera (Ashwagandha), Allium sativum (garlic), and Curcuma longa (turmeric), and to investigate their wound healing activities upon topical application on full-thickness skin wounds induced surgically in Rabbit. Methods: Experimental study was conducted using thirty adult male rabbits. Animals were randomly allocated into 6 groups each containing 6 animals. Animals in group 1 were without treatment and served as control. Animals in group 2 received the carbomer gel base not containing drugs. Animals in group 3 received herbal gel containing withania extract. Animals in group 4 received herbal gel containing garlic extract. Animals in group 5 received herbal gel containing curcuma extract. Animals in group 6 received gel containing ciprofloxacin. Gel was applied on wound once daily up to 14-18 days starting from the second day of wounding. Results: The wound healing was slower in the untreated control animals as well as the animals treated with carbomer gel base where wounds completely healed by the 18th day of experimental period. In the other hand, wound healing in animals treated with withania gel reached about 90% by the 12th day and completely healed by the 14th day. Notably, wound healing reached about 90% by the 10th day and 97% by the 12th day and completely healed by the 14th day. Additionally, wounds in animals treated with curcuma gel cured about 90% by the 14th day and completely cured by the 16th day. Moreover, wound healing reached more than 90% by the 12th day and completely healed by the 14th day in animals treated with ciprofloxacin gel. Conclusions: Topical application of gels containing the extracts of withania, garlic, and curcuma has fastened the rate of healing in wounds induced surgically in rabbits.

Maharashtra handicrafts are rich in variety and selection. Maharashtra handicraft industry produces many unique and interesting crafts of Maharashtra that are used in daily needs. Given the fact that the population of Maharashtra is the second highest in the nation, the diversity in the state and its affairs of cuisines, customs traditions and handicrafts is natural. The state of Maharashtra has a huge and rich culture of Handicrafts. Apart from that, the state beholds an array of visual and audio delight for the tourists to cherish. Certain cities like that of Pune, Nasik, Kolhapur, Aurangabad, Ajanta Ellora Mumbai and Nagpur are the ones that boast of utmost tourist value. Apart from these, the state also boasts of a very rich and varied culture of Handicraft which is evident from the rich value that they add to the nation’s creative wealth. The availability of Handicrafts and its diversity in Maharashtra is huge. Their tradition is lent to them by the Mughals, the Marathas and even by the British. The true culture of Maharashtra can be identified with its exaggerated handicrafts. Some of the standout works in the state of Maharashtra includes the famous Sawantwadi work, leather works, Bidri works, weaving, Himru and Mashru, Jewelry, Paintings and much more. They not only highlight the creative spirit of the state but also show their sense of art and design. The handicrafts of the state are also a true representation of the lively spirit of the state. The most exciting gift of the state is the handicrafts of this place. They not only cater to the eyes but also render a heart a soothing touch that the tourists take back home lively. One of the standout craft in this state is the Sawantwadi state. The weaving culture of the state is very evident and is famed across the nation and even globally. These entire products merge together to make a front of creativity that the state beholds of

Background: Nurses are the major work force of any health care. Highest incidence rates of work-related low back problems seen among nurses. Thus the present study was conducted with the aim to determine effect of conventional therapeutic exercise on low back pain. Methods: Quasi experimental research design was adopted with 60 samples who met the inclusion criteria. Samples were allocated into experimental group (n=30) and control group (n=30) by convenience sampling technique. Pre-test was conducted by using Numerical pain rating scale and Rolland Morris Low Back Pain and Disability Questionnaire in both experimental and control group. Conventional therapeutic exercise was administered to the experimental group and the control group was continued with the routine procedure. Post-test was conducted after 2 weeks with same tool for both the group. Data were analyzed using SPSS. Results: The study findings revealed that the low back pain and its related disability was present among staff nurses working in intensive care unit and operation theatre. Conventional therapeutic exercise was effective in reducing the level of low back pain at the level of p<0.001 in the experimental group. Conclusion: Conventional therapeutic exercise may be routinely practiced in the hospital thereby preventing the low back pain which in turn makes the nurses efficient to provide productive and quality nursing care.

Kiloh-Nevin syndrome is one of the neuropathies where anterior interosseous nerve gets compressed by accessory head of flexor pollicis longus muscle. This study was designed to look for prevalence, morphology and relation of accessory head to anterior interosseous nerve. The present study was conducted in the Department of Anatomy, Sree Narayana Institute of Medical Sciences, and Ernakulam. 50 upper limb specimens were dissected to expose the accessory heads and its relation to anterior interosseous nerve. The number of accessory heads was noted down and length of the muscle belly was measured with vernier callipers. The accessory heads were present in 18 specimens (36%). 12 specimens with accessory head were observed to get inserted to tendon of flexor pollicis longus and 6 specimens to tendon of flexor digitorum profundus. Double accessory heads were observed in 3 specimens (6%). 3 specimens showed origin of accessory heads from flexor digitorum superficialis. Double accessory heads arising from flexor digitorum superficialis got inserted into flexor pollicis longus and flexor digitorum profundus separately. The accessory heads were related superficially to anterior interosseous nerve in all specimens. The mean length of accessory head on right side was 6.9 cms and 7.4 cms on the left side. The presence of accessory heads to flexor pollicis longus or flexor digitorum profundus acts as a trigging factor for compression of anterior interosseous nerve. The below results will give an additional information to surgeons who approach upper end of radius from anteriorly and even clinicians can plan appropriate management for compression syndromes.

Backgrounde: Nitrates and nitrites are naturally found in fruits, vegetables and grains. In addition, they are used as food additives, preservatives and colour fixatives. Nitrite toxicity is induced by formation of methaemoglobin, and carcinogenic substances e.g. nitrozoamines. Materials and methods: In the current study we explored the impacts of chronic exposure of albino rats to potassium nitrate. Fourteen rats were randomly divided into 2 groups (n=7), control group and potassium nitrate treated group in dose of 20 mg/kg for 3 months. Subsequently, urine and blood samples were collected at 1, 2 and 3 months. At the end of the experiment (3 months), rats were sacrificed and thyroid glands were harvested. Results: Biochemical analysis exhibited significant decrease in the urinary iodine and blood-based thyroid hormones (T3 and T4), vitamin A compared with matched-time control group. However, calcium, nitric oxide and MDA showed significant increase in potassium nitrite treated rats. Marked thyroid injury was observed in the form of size and shape of the thyroid follicles, some follicles were enlarged and filled with colloid fluids, but other were completely empty upon sodium nitrite exposure. Moreover, in some cases hyperplasia with leukocytic infiltrations in the parafollicular cells replacing the atrophied follicles. Conclusion: Our results provide new evidences that toxic effect of potassium nitrite is possibly mediated by inhibition of iodine absorption,vitamin A level, thyroid destruction and depression of the antioxidant system.

Vast number of the females in this part of the population suffers from the thyroid illness and majority of them comes to the hospital after suffering from the same illness for a long time. They will not know before the parameters of the blood are out of proportions. This study puts in an effort to find the base proportions of the USG gland in normal female patients and tries to establish a normal paremeters of the thyroid gland. Many cadaver based study are there but not even a single female dedicated USG based morphometric analysis is not found in the open access journals

This study aimed to compare the effect of simulated brushing on one Nano resin-coated glass ionomer (GI) (EF; Equia forte fil/Equia forte coat, GC Corp., Tokyo, Japan) and one Nano zirconia-reinforced GI (ZI; Zirconomer Improve, Shofu, Inc., Kyoto, Japan). One hundred and forty specimens were prepared and divided into two groups: EF and ZI. The Vickers Hardness Number (VHN) and surface roughness (Ra) were measured before and after simulated brushing of the specimens with water or with water and Colgate Total 12 (CT12) for 5,000, 10,000, and 20,000 cycles. Regardless of condition, EF and ZI showed statistically significant differences of mean VHN: 146.90 ± 36.66; 110.30 ± 13.73, (p-value < 0.001), and mean Ra: 0.290 ± 0.089μm; 0.247 ± 0.085μm (p-value ≤ 0.05), respectively. For both EF and ZI, repeated measures analysis of variance (ANOVA) revealed a statistically significant difference of mean VHN (p-value ≤ 0.05) in all cycles’ intervals with CT12, but only at 20,000 cycles with water and in Ra (p-value ≤ 0.05) in all conditions compared to the control group. A post-hoc Tukey’s test revealed a statistically significant difference of mean VHN in water vs. CT12 (p-value ≤ 0.001) for both EF and ZI in all conditions. The EF showed higher mean surface hardness and higher mean surface roughness as compared to the ZI. Both the EF and ZI specimens demonstrated resistance to the softening when being subjected to the simulated tooth brushing procedure equivalent to about 1 year of clinical use.