Valvular heart diseases affects millions of patients worldwide, and the burden is rising as the population ages. Severe valvular heart disease is associated with significant morbidity and mortality, claiming over 50,000 lives annually in the USA [1]. Coumadin (generic name: warfarin) is an anticoagulant, which stops the formation of blood clots and makes blood thinner (less viscous). As for Vitamin K, it helps the process of blood clotting. In other words, warfarin has the opposite effect to Vitamin K. Warfarin is a widely used and cheap drug which decreases the risk of thrombosis or embolism in patients with diseases such as atrial fibrillation (AF), venous thrombo-embolism, and mechanical heart valve surgeries. Treatment with warfarin requires close monitoring with regular tests of PT-INR for better outcome of patients [2]. The purpose of the study is to shorten and simplify the process for the testing and prescription of warfarin by introducing point of care analysis (POC). The aim was also to evaluate changes in time and cost related to the new processes. Effective management of warfarin therapy is frequently challenged by its difficult pharmacology and adverse effects. One strategy to ensure safe warfarin use is provision of comprehensive warfarin education to patients regarding self-testing and self-management of accurate dose according to INR value. Point of care INR monitoring has shown beneficial impacts on the risk of thromboembolic events, anticoagulation control, patient satisfaction, and quality of life [3].

This research is to test the influence of professional commitment and locus of control on whistleblowing intensity through ethical sensitivity at Public Accounting Firms in Makassar. Data was obtained from 4 Public Accounting Firms in Makassar. Primary data was obtained through field research by distributing questionnaire/statement sheet to 31 respondents. Data analysis method was path analysis processed by SPSS-21 program. The research results show that professional commitment and locus of control have partial positive and significant effects on the ethical sensitivity. In addition, professional commitment has positive and significant effects on whistleblowing intensity, locus of control has positive yet insignificant effects on whistleblowing intensity, and ethical sensitivity has positive and significant effects on whistleblowing intensity. Meanwhile on the intervening variable, professional commitment and locus of control have partial effects on whistleblowing intensity through ethical sensitivity.

Aim: To assess the effects of a voluntary, community-oriented campaign using social media through a multidisciplinary approach on body weight. Setting and Design: A survey, community-oriented using popular social media accounts. Methods: 268 followers from the community participated in the study using a questionnaire, which was constructed by a study group and self-filled online using google drive. Results: A total of 268 followers participated in the study. A healthy program had been applied by 43.3% of the survey respondents, consisting of a unified healthy diet and mild-moderate intensity exercises for less than a year, while only 13.1% applied it for more than a year. Almost half the survey respondents (48.5%) followed the campaign for less than one year, and 41.8% for more than one year. There were changes in diet and nutritional habits on the followers, after following/applying the healthy program. Their habit of practicing physical activities was improved. The voluntary community campaign raised awareness among participants and produced positive psychological eating behavioral changes. Conclusion: There was a significant difference in weight reduction after following the healthy program for more than one year and to a lesser extent for those who followed it for less than one year.

The study examined the impact of working capital management on the profitability of Pharmaceutical firms listed on the Nigerian Stock Exchange market. Correlation and ex-post facto research design were used in a sample of 5 Pharmaceutical firms. Secondary data for a period of 5 years (2013-2018) was used, and Ordinary Least Squares (OLS) multiple regression was employed in data analysis. The study found that working capital management (account receivables collection management, accounts payables management, inventory management, cash conversion cycle management, operating cash flow management) has a significant impact on the profitability of listed pharmaceutical firms in Nigeria. It is therefore recommended among others that managers should focus on reducing inventory days, collect receivable as soon as possible because it is better to received inflows sooner than later, and delay payment of creditors in order to invest the money in short-term securities which are profitable. Also, the cash conversion cycle should be elongated to the extent that it maximizes profit.

A medico-legal autopsy on an adult if performed completely and systematicall, with a reasonable uniformity and clarity can help in the betterment of outcomes while providing justice. The pre-requisites prior to an autopsy, and a thorough external examination are very important before moving on with the internal examination. In many situations a proper external examination will be sufficient to give a medico-legal report; if done methodically. There are four types of skin incisions employed in a medico-legal autopsy to examine three body cavities. The internal examination can be done using four dissection techniques as outlined in the existing literature. Examination of brain, heart, neck structures, spinal column and genitalia are very important and requires an organized approach in order to not to miss salient findings. Finally, while closure of the cadaver the doctors must bear a very important fact in mind that the body on the table was once housed by a living being and hence s/he must be treated with the same respect and dignity as one would expect him/herself to be treated by others.

Assembly line balancing (ALB) is used in many industries to minimize the number of stations, improve the efficiency and work load balance among stations. Enhanced Genetic Algorithm (EGA) is proposed using precedence preservative crossover and scramble mutation techniques, aiming to minimize two objectives; number of stations as a primary objective and smoothing index as a secondary objective. Benchmark problems were selected from the literature, used to test the efficacy of the algorithm and to compare the results with the well-known algorithm SALOME. The results showed high efficacy while handling two objectives. It outperformed SALOME in work load balance and efficiency. On the other, EGA outperformed the Genetic Algorithm (GA) developed by [1] in minimizing the number of stations.

This research paper deals a study of the portraits of black women as wives involves an understanding of the role of women as wives in Africa in the pre-colonial times. This is necessary as certain notions about womanhood persist even today in the post-colonial Africa. Black women in the U.S.A. have their roots in Africa as their ancestors were taken mostly from the West Coast of Africa to work as slave’s n the plantations of America. Their ideas about the role of men and women were shattered by the system of slavery and very little remained of their traditional roles that affected man-woman relationship. The most important factor with regard to the women in traditional society is their roles as mothers. The importance given to mothers and the high regard in which they were held has been explained in Chapter II. Filomina Chioma Steady points out that “women are important as wives and mothers since their reproductive capacity is crucial to the maintenance of the husband’s lineage and it is because of women than men have a patrilineage at all” (Steady, 29). This original research paper portrays the situations of house wives in those novels very clearly.

Generalise gravity model used to evaluate the effect of exchange rate volatility and exchange rate regime on bilateral exports of Pakistan. A bilateral data set of major exports partners the USA, UK, UAE, Hong Kong and Germany for period 1982 to 2015 used in a panel framework. ARCH, GARCH, moving average standard deviation methods used for measuring volatility in bilateral exchange rate. The results found conclude that economics size (GDPJ/GDPPAK) has a significant positive effect. Distance (DIS) and relative prices (RP) are significant negative effects; exchange rate volatility and free-floating exchange rate regime have a significant positive effect on aggregate bilateral exports of major trading partners of Pakistan.

Purpose: This study investigates English studies in Nigerian universities and the implications of such studies on nation-building. Method: Fifty (50) research instruments (questionnaires) were administered to three categories of respondents: Nigerian undergraduates (15 questionnaires); academic staff of Nigerian universities (15 questionnaires); employers of labour in Nigeria (10 questionnaires); employees in Nigeria (10 questionnaires). The theoretical underpinning of this study is the Sociology of Language Approach. Results: The analysis reveals that: the importance of English studies in Nigeria is widely acknowledged; different factors bedevil English studies in Nigerian universities; and formal education fails to accomplish the goals of English studies in Nigeria. Conclusion: In this study, literacy in English is “the ability to use the English language with significant proficiency in spoken and written communications, such that graduates of Nigerian universities can perform satisfactorily at work-places, irrespective of their disciplines.” In Nigeria, literacy level in English is not satisfactory, and this situation hinders nation-building. Given the significance of English studies all over the world and in Nigeria in particular, all stakeholders should foster the teaching and learning of the English language.

This paper addresses the importance of kinesitherapy in improving coxarthrosis. Coxarthrosis is also known under the names of hip arthrosis and hip osteoarthrosis and it represents a degradation of the hip joints caused by a morphological and functional lack of balance, being the most frequent hip disorder. The aim of this work is to propose a kinesitherapy programme that slows down the evolution of joint injuries, in the presence of a physical therapist, but also a potential use of the respective programme in the situation of the necessity of an intervention through kinesitherapy in the absence of a specialised physical therapist, because in progressive degenerative diseases, patients are obliged to continue their programme at home. Following the development of the experimental kinetic programme, the subjects were evaluated by means of the Lequesne questionnaire for hip arthrosis, the control of active and passive joint mobility; global muscular power was tested, and on the basis of Trendelenburg’s sign.

Objectives: The study was planned to evaluate the role of morphometric analysis of foramen magnum in determining sexual dimorphism. Also, we have compared the measurement of foramen magnum with age of individual. Material & Methods: study was retrospectively and scans of CBCT were retrieved from archives of department. Length and width of foramen magnum in adults was measured. The data was statistically analyzed. Results: Mean length and width of foramen magnum was greater in males (34.65mm, 31.22mm) as compare to females (33.59mm, 30.11mm) and it was statistically significant (p<0.05). Mean length decreased in dimension i.e. from 35.22mm to 33.73mm as age progressed (18-60 years). Conclusion: Sexual dimorphism can be determined using foramen magnum dimensions. However, age estimation by morphometric analysis of foramen magnum requires more research.

Claim has always been made that thought and language are inseparatable phenomena. Accordingly, major debate has revolved around the dependence or interdependence of language and thought. Based on linguistic relativity hypothesis, our perception of reality depends on the language we speak. The counterclaim has also been made that languages are not so much different and this makes us skeptical of the idea that their speakers have different thoughts. Some hold the belief that language may not serve a proper medium for thought, mentioning extralinguistic drawbacks such as ambiguity, deixis, and co-reference. All in all, it seems rational to maintain that thought and language have compromised to coexist and attempts to prioritize one over the other are mythical if not too much simplistic.

Objectives: The study was done to evaluate efficacy of chemiluminescent method (vizilite) as a screening test in detecting the malignant changes in potentially malignant lesions of oral cavity. Study also compares sensitivity and specificity of toludiene blue with chemiluminescent method. Materials & methods: 30 patients clinically diagnosed as potentially malignant lesions of oral cavity were recruited. After obtaining consent form, all patients were subjected chemiluminescent method and toludiene blue. All patients were then compared with histopathological results and statistically analyzed. Results: After histopathological results, Sensitivity and specificity of vizilite was found to be 66.6% and 71.4% respectively and that of toluidine blue was 77% and 87%. Conclusion: Although vizilite accentuated the visibility of the lesion but overall detection rate in patients was not significantly improved. Qualities like easy to perform, less time consuming and instant results concur with the properties of an ideal screening test but diagnostic propensity is questionable.

Aim: This research is aimed at the comparison of the amount of weekly physical activity of professional soldiers of the Army of the Czech Republic (soldiers of the 7th mechanized brigade) during an ordinary week spent in the garrison and during a week of continuous field training. Methodology: The observed group was made up of 48 professional soldier volunteers in the age range of 30.12 ± 4.84 years. The measurement has been performed continuously during the time span of one week. Physical activity has been measured with the utilization of the ActiGraph GT1M accelerometers supplemented with the use of a weekly physical activity protocol. Results: Based on the results it is possible to infer that no difference has been found between the amount of weekly physical activity of the soldiers during a week spent in garrison and during a week of continuous field training in a military training area. The level of physical activity has been sufficient during both of the weeks. The average active energy expenditure has been 18.27 kcal higher during the week of continuous field training. The average active power has been 5.06 kcal/hour higher during the ordinary week spent in garrison. Conclusion: Based on the values of average daily step count during an ordinary week in the garrison and during a week of continuous field training the soldiers´ activity can be categorized as regular medium intensity movement without competitive sport activity (Máček et al., 2010) and meets the healthy recommended value of number of steps per day (Aoyagi & Shephard, 2009).

Stem cells are biological cells that are undifferentiated and can be differentiate into specialized cells. They are of embryonic or adult stem cell. Another classification is dental pulp and bone marrow- derived. Bone marrow type stem cells are commonly used for regenerative procedures in prosthodontics. They have excellent regenerative ability without neoplasm formation. They help to build the bone structures of the craniofacial region, particularly the maxilla and mandible. Stem cell therapy can revolutionize next era in regenerative prosthodontics.