Intraosseous or intradiploic arachnoid cysts of the cranial vault are extremely rare lesions, representing herniations of the arachnoid membrane through a dural and inner table defect. A 35-year-old woman presented with progressive headaches and a slowly enlarging, non-tender left parietal swelling without any history of trauma. Imaging revealed a left parietal intraosseous cystic lesion with CSF-like signal intensity, thinning of the outer table, and communication with the subarachnoid space. Surgical exploration confirmed multiple small openings in the outer table with CSF outflow and an underlying dural defect. The cyst was excised, the dura repaired watertight, and the cranial vault reconstructed. The postoperative course was uneventful, and follow-up imaging at three months showed no recurrence. This case highlights an exceptional presentation of an intraosseous arachnoid cyst with dural communication. Recognition of this rare entity is essential for accurate diagnosis and proper surgical management.

Data centers serve as specialized operations centers that provide organizations with the ability to manage and analyze massive quantities of data that are necessary to support their operations. Data centers have been developed to support the increased demand for IT services, which is largely due to security concerns related to the transfer of large volumes of data over the Internet and the increased use of remote devices for business purposes. Data centers have been built with the concept of centralizing IT infrastructure as a means to improve security, control and increase productivity, and provide scalable resources to meet the needs of organizations. However, increasing the capacity of a data center presents a number of potential problems for organizations including incorrect installation of hardware and improper wiring of the data center. In response to the unique challenges that organizations face in successfully completing data center expansions, Microsoft provides a tool called Bootstrap Lite (BSL) that is designed to provide assurance that the configuration of hardware and racks meet established design specifications thus, improving both reliability and efficiency, while reducing error rates and increasing the time required to build out a data center. Various considerations are required when planning for data center expansions including the following considerations: Scale of the data center, power and cooling needs of the data center, security requirements of the data center, network connectivity to the data center, environmental sustainability of the data center operations, regulatory compliance of the data center, disaster recovery options associated with the data center, redundancy of the data center, and extensive hardware testing of the data center. In addition, BSL supports organizations in maintaining high levels of performance and reliability for their data centers, providing assurance that data centers will remain secure and adaptable to the changing needs of the organization in the digital economy.

The goal of this project is to modernize BP's OPSD2 Downstream Logistics ETL Solution by moving away from Mainframe DB2 database systems and using Oracle-based DBs and incorporating multiple source data sources through Informatica Mappings using an Agile Governance framework for ETL solutions. This study uses InformaticaPowerCenter's Repository-Integration service architecture to analyze the performance characteristics of InformaticaPowerCenter and find that Read Operations can scale efficiently under high levels of concurrency while Write Operations experience rapid degradations in performance due to the use of exclusive locks on certain tables. Therefore, there is a risk of failure if high-volume deployments are attempted using a Write Operation approach. Performance analysis performed using multiple tools have identified that the write latency is the primary cause of the performance constraint. To alleviate this issue, it is recommended that cache tuning, repository clustering and asynchronous bulk logging be used to meet the operational demands of fuel distribution. Looking forward, OPSD2 intends to evolve into BP's Real-time Net-Zero Analytics Platform by leveraging cloud-native solutions based on Informatica IDMC and Advanced Streaming capabilities.

Collision tumors are defined as ≥2 histologically distinct tumors existing in the same anatomic location. Generally, collision tumors are rare, and if they occur in the sellar region, common combinations are pituitary adenoma with Rathke cleft cyst (most common), however the association of pituitary tumors with hypopthalamic tumors remains extremely rare. We report in an observation the case of a pituitary adenoma diagnosed after 5 years of a surgical cure of a craniopharyngioma. Although described in a few observations through the medical literature, it is an extremely rare condition illustrating the possibility of having 2 different neoplasias, within the hypothalamic-pituitary region. The chronology of the appearance of the 2 histological entities (or more than 2) is decisive first on a semantic level, this then allowing to better classify into one of collision, composite, or in coexistence forms. The management of these tumors of the pituitary region involves effective surgery but also a good endocrine evaluation in order to treat pituitary hormone deficiencies, sometimes with a vital prognosis (replacement with corticosteroids and thyroxin), or functional (GH, sexual steroids and gonadotrophins). The prognosis of these tumors that occurred in a collision mode remains less good compared to solitary tumors of the hypothalamic and hypopjhyseal region.

Background: Cervical cancer remains a significant health burden globally, and early diagnosis of precancerous lesions is paramount in prevention. Colposcopy-directed biopsy has been considered the gold standard to evaluate abnormal cervical cytology, but the correlation of colposcopic impression with histopathological examination has to be revalidated regularly in order to optimize screening programs. This study will correlate colposcopic findings and scoring indices with biopsy results to identify features that predict high-grade cervical lesions. Methods: 90 women with suspicious cervical findings or abnormal cytology were included in this cross-sectional study, who had received colposcopy and colposcopy-guided biopsy at a tertiary care hospital from July, 2023 to June, 2024. Colposcopic images were captured by routine procedure after acetic acid and Lugol's iodine staining. Reid Colposcopic Index and Swede Score were calculated for each case. Biopsy samples were obtained from the area of abnormality and were histopathologically graded as negative/inflammatory, LSIL (CIN 1), or HSIL (CIN 2-3). Data were analyzed in SPSS, including correlation coefficients, and logistic regression analysis was carried out. Results: Out of 90 patients, 38 (42.2%) had HSIL and 34 (37.8%) had LSIL, and 18 (20.0%) had negative/inflammatory findings on histopathology. Colposcopy was 81.6% sensitive and 76.9% specific for HSIL detection (AUC=0.85). There were high correlations between the Reid Index and histopathology (r=0.68) and the Swede Score and histopathology (r=0.72). Swede Score ≥8 (AOR=17.3, 95% CI 3.1-95.8), lesion involving ≥2 quadrants (AOR=7.39, 95% CI 2.07-26.3), and atypical vessels (AOR=8.25, 95% CI 1.33-51.2) were independent predictors of HSIL. Conclusion: Colposcopy has exceptional diagnostic accuracy in the detection of high-grade cervical precancerous lesions, and standardized scoring systems significantly improve predictive performance. These findings support colposcopy-directed biopsy as a safe technique for diagnosis in screening programs for cervical cancer.

Spectrum Mobile became a large provider of mobile services in the US after being acquired by charter communications. The speed with which a company can grow increases the complexity of its system, which in turn leads to new challenges. Spectrum Mobile faced a number of challenges: inconsistent releases, delays in testing changes, etc. To overcome these challenges, the QA/DevOps team started working on four key elements within their overall testing procedure: compliance, resiliency, automation, and modernization. Several key initiatives were started as part of this new initiative including the implementation of CI/CD pipelines in the cloud to automate the customer experience; the creation of a "hotfix" lane for addressing critical issues in real time. New technologies such as Blue/Green deployments and service virtualization were utilized to address middleware instability and scalability issues within the company. By leveraging new technology, Spectrum Mobile was able to enhance the speed with which it releases new products and services to customers, improve the availability of their systems, and create a 50% increase in its number of subscribers and protect a large amount of revenue. This case study also illustrates how the modernization of legacy systems will continue to be necessary to maintain competitive advantage in the telecommunications industry. In addition, the case study indicates how cloud-based and AI-based technological advancements will enable Spectrum Mobile to develop automated and scalable architectures in the future. Spectrum Mobile will continue to explore the potential of artificial intelligence (AI), predictive analytics, and sustainable networks to support the evolving needs of society through technology.

Artificial intelligence (AI) is transforming diagnostic decision-making across the life sciences, yet evidence remains fragmented across human, veterinary, plant, environmental, and microbial domains. We conducted a PRISMA-ScR scoping review (protocol preregistered on OSF; details in Supplement) and bibliometric analysis covering 2015–2025. Searches in PubMed/MEDLINE, Scopus, Web of Science, and IEEE Xplore (plus arXiv/bioRxiv tagging) identified 28,541 records and 68 preprints; after de-duplication and dual screening, 689 primary studies met inclusion criteria (with 42 preprints analyzed descriptively but excluded from citation-based bibliometrics). Human medicine dominated the corpus (81.3%), followed by veterinary (6.2%), plant (5.1%), environmental (4.2%), and microbial diagnostics (3.2%). Modalities were led by medical imaging (65.0%), then omics (18.0%), time-series (8.1%), spectra (4.1%), text (2.9%), and eDNA (1.9%). Reported performance was high (median AUROC 0.94), but external validity and transparency were limited: only 28.0% performed external validation, 9.0% used prospective designs, and 5.2% reported probability calibration. Reproducibility signals were weak (code availability 22.9%, data availability 18.0%, explicit preregistration rare), and fairness/bias assessments appeared in 7.0% of studies, concentrated in human health. Bibliometrics showed rapid year-on-year growth, with the United States (32.1%) and China (28.4%) leading output and collaborations. Trends indicate a shift from task-specific CNNs to multimodal/foundation-model approaches and early data-fusion gains, but consistent gaps persist in leakage controls, calibration, subgroup reporting, and regulatory alignment. We recommend domain-aware, leakage-resistant splits; at least one independent, real-world evaluation; prevalence-aware metrics with calibration and decision-utility; open datasheets/model cards; and federated/external benchmarking to probe generalization. These practices can convert impressive internal results into dependable, equitable diagnostics that work across clinics, farms, rivers, and labs.

This study examined environmental adult education for curbing the effects of illegal oil bunkering on Ogoni land, Rivers State. It was guided by three research objectives and three research questions, The population for this study consisted of 1,499 members of 20 Community-Based Organisations (CBOS), which were drawn from farmers and fisherfolk in Gokana and Khana Local Government Areas of Rivers State, out of which 400 CBO members were sampled through a simple random sampling technique. The instruments for data collection were a validated self-developed questionnaire titled “Environmental Adult Education Programme as a Tool for Reducing Community Participation in Illegal Oil Bunkering Questionnaire (EAETRCPIOBQ)”. The instrument had a reliability index of 0.87. Data collected were analyzed using the mean statistics and standard deviation Findings revealed that poverty, unemployment, a lack of livelihood alternatives, weak institutional frameworks, and systemic corruption are central factors sustaining illegal oil bunkering in Ogoni land, despite government intervention. Community members in the area of study are environmentally aware of the impacts of illegal oil bunkering. Based on the findings, the researcher recommended, among other things, that the establishment of job programmes, skill acquisition facilities, and sustainable livelihood prospects in Ogoni land should be given top priority by the government, oil corporations, and development partners.

This systematic literature review examines the evolving role of the Scrum Master in contemporary project management, addressing how this critical agile leadership position has transformed since its original conception. Guided by the PRISMA 2020 framework and employing a PICO-informed search strategy, this study synthesized qualitative insights from peer-reviewed academic and grey literature published between 2010 and 2025. Thematic analysis revealed five major themes characterizing the role's evolution. First, the Scrum Master maintains a foundational identity as a servant leader who facilitates self-organization, though this ideal often conflicts with organizational pressures. Second, the role has expanded beyond its original scope to encompass coordination across scaled agile environments, global distributed teams, and remote work contexts. Third, Scrum Masters function as cultural catalysts who build organizational trust rather than merely managing processes. Fourth, role hybridization has emerged as a prevalent pattern, with Scrum Masters frequently assuming project management responsibilities that create accountability conflicts. Fifth, professionalization through structured competency frameworks and mentorship programs reflects the discipline's maturation, though gaps remain in practitioner supply and diversity. These findings reveal that while servant leadership orientation remains theoretically consistent, practical enactment varies substantially based on organizational maturity and structural clarity. The review identifies implications for organizations optimizing agile transformation, including the need for clear role boundaries and recognition of the Scrum Master as an organizational change agent. Future research should employ longitudinal designs and address diversity dimensions within the profession.

Background: Levothyroxine (LT4) therapy is highly effective for biochemical correction of hypothyroidism, yet many patients report persistent symptoms and reduced health-related quality of life (HRQoL) despite achieving target thyroid-stimulating hormone (TSH) levels. Whether alternative management strategies meaningfully improve HRQoL remains clinically important. Aim: To systematically review and qualitatively synthesize evidence on the relationship between hypothyroidism management approaches and patient quality of life. Methods: A systematic review was performed following PRISMA principles. Eligible studies were primary clinical studies evaluating adults with hypothyroidism or subclinical hypothyroidism in which HRQoL was measured and related to a management approach, treatment strategy, formulation, or biochemical response. Nine studies met eligibility and were synthesized qualitatively due to heterogeneity in populations, interventions, comparators, and HRQoL instruments. Results: Evidence from large randomized trials in older adults with subclinical hypothyroidism showed no clinically meaningful HRQoL benefit from LT4 compared with placebo or usual care. In primary hypothyroidism, switching from LT4 tablets to liquid LT4 was consistently associated with improved patient-reported QoL in selected cohorts, often without major changes in thyroid biochemistry. Trials of LT4/LT3 combination therapy generally did not demonstrate consistent HRQoL superiority over LT4 alone, although some studies reported patient preference or selective domain improvements. Observational studies and surveys repeatedly documented impaired HRQoL among LT4-treated patients compared with controls, and HRQoL was frequently weakly correlated or not correlated with TSH/FT4 within the reference range. Conclusion: Quality of life in treated hypothyroidism is influenced by more than biochemical normalization alone. LT4 treatment in older adults with subclinical hypothyroidism does not appear to improve HRQoL, while liquid LT4 may improve HRQoL in selected, dissatisfied, or absorption-challenged patients. Combination therapy remains an inconsistent strategy for HRQoL improvement. Future research should prioritize patient-centered outcomes, identify phenotypes of persistent symptoms, and test targeted management pathways using validated thyroid-specific HRQoL instruments.

An electrically-operated California Bearing Ratio (CBR) machine was designed, fabricated with locally-sourced materials, calibrated and tested with the aim of providing high precision machine obtainable at lower cost. Materials were selected based on the ability to withstand mechanical loads, stiffness and dimensional stability, wear resistance, corrosion resistance, machinability and cost-effectiveness. The major component parts were designed using standard equations. For material components such as the loading frame, CBR moulds and reaction rings, mild steel was used, hardened medium carbon steel was used for the plunger, while high-grade spring steel was used for the load-measuring components for high elastic recovery. Calibration result gave proving ring constant as 0.02 kN/div. CBR test results on soil samples under unsoaked conditions gave CBR values ranging from 4.85 – 6.91 %, indicating poor to fair soils requiring stabilization or treatment for subgrade material. For soil tested under soaked conditions, the lowest CBR value of 0.82% showed poor subgrade soil that requires substantial stabilization, while the sample with the highest CBR value of 3.15% requires significant improvement. Statistical analysis of data using Minitab software version 2018 applied Fisher Pairwise tests for differences of means at 95% level of significance, which showed that soaked 2.5mm and unsoaked 5mm samples with P = 0.007 and soaked 5mm and unsoaked 5mm with P = 0.14 are significantly different for the top, and soaked 2.5mm and unsoaked 5mm having P = 0.028, are significantly different for the bottom. CBR values for all other top and bottom samples are not significantly different.

Plants are continuously exposed to diverse environmental stresses, including drought, salinity, temperature extremes, and nutrient limitations, which significantly constrain agricultural productivity and ecosystem stability. Understanding how plants perceive, integrate, and respond to these stresses at the genetic level has become a central focus of modern plant science. Recent advances in genomics, transcriptomics, and functional genetics have revealed that plant adaptation to environmental stress is governed by complex, multilayered regulatory networks rather than single stress-responsive genes. These networks involve stress-sensing mechanisms, signal transduction pathways, transcriptional reprogramming, and post-transcriptional regulation, collectively shaping plant performance under adverse conditions. Genetic variation within and among plant species provides a critical resource for stress tolerance, enabling plants to optimize growth, metabolism, and reproductive success in fluctuating environments. Moreover, emerging tools such as genome-wide association studies, epigenetic profiling, and genome editing technologies have accelerated the identification of key genetic determinants underlying stress resilience. Integrating genetic insights with physiological and ecological perspectives has enhanced our understanding of how plants balance stress tolerance with growth and yield. This trade-off is particularly relevant under climate change scenarios. This review synthesizes recent progress in elucidating the genetic mechanisms that drive plant adaptation and performance under environmental stress. It highlights major stress-responsive gene families, regulatory networks, and adaptive strategies, and discusses how these insights can be translated into crop improvement programs. By bridging fundamental genetic research with applied plant breeding, this review underscores the potential of gene integration to develop resilient plant systems capable of sustaining productivity in increasingly challenging environments.

Background: Extra-short dental implants have emerged as a reliable option for rehabilitating posterior areas with limited vertical bone availability. However, clinical evidence regarding their use as single-unit restorations under immediate loading protocols in the mandibular first molar region remains scarce. Purpose: To evaluate implant survival, marginal bone loss, and biological and prosthetic complications associated with single extra-short implants (5.5 and 6.5 mm) immediately loaded in the mandibular first molar position. Materials and Methods: A retrospective study was conducted including 19 patients rehabilitated with 19 extra-short implants placed in the mandibular first molar region between June 2019 and June 2023. All implants were restored with single screw-retained crowns on a unitary transepithelial abutment and immediately loaded within 24 hours. Implant survival and marginal crestal bone loss were assessed radiographically. The mean follow-up period was 38.6 ± 10.5 months. Results: No implant or prosthetic failures were recorded during the follow-up period, resulting in a cumulative survival rate of 100%. Mean marginal bone loss was 0.36 ± 0.13 mm mesially and 0.60 ± 0.16 mm distally. No clinically relevant biological complications were observed. Conclusions: Within the limitations of this retrospective study, immediately loaded single extra-short implants placed in the mandibular first molar region demonstrated favorable clinical outcomes. Careful case selection, conservative surgical protocols, and standardized prosthetic design appear to be key factors for achieving predictable results in this demanding clinical scenario.

The integration of Artificial Intelligence (AI) technologies is fundamentally reshaping the legal profession, presenting both unprecedented opportunities for efficiency and innovation, and profound ethical and professional challenges. This article argues that the imperative for robust AI ethics must be conscientiously integrated into legal education, particularly within vocational institutions like the Nigerian Law School (NLS). Drawing on an analysis of AI’s role, history, and defining characteristics, the article identifies critical ethical sustainability challenges, including algorithmic bias, data privacy breaches, challenges to academic integrity (such as plagiarism and unauthorized content generation), and the critical issue of accountability for AI-generated legal errors. The article proposes that legal education must shift its focus from preventing AI use to teaching responsible, ethical use, equipping future practitioners with the requisite technical literacy, critical thinking, and human judgment necessary to mitigate risks and uphold core professional duties, such as competence, integrity, and the duty not to mislead the court. Ultimately, fostering a culture of ethical and responsible AI engagement is essential to ensure the long-term viability and integrity of the legal profession in the digital age.

Digital health change has now become a strategic priority in the world health care system, but it has been indicated that investing in technology does not guarantee a better outcome in healthcare. Efforts that are made at the organisational and managerial levels are critical determinants of whether the digital health initiatives will deliver anything significant. The purpose of this research was to investigate how a change management affects the work of digital healthcare on the example of a knowledge transfer mediator, and the evidence accessible and applicable in large healthcare systems, i. e. Saudi Arabia was considered. A qualitative systematic review approach was chosen with the help of the Preferred Reporting Items Systematic reviews and meta-analyses (PRISMA) framework. The systematic search through five academic databases revealed 200 records out of which 20 qualitative and mixed-method studies that were peer-reviewed were incorporated in the eventual synthesis. The results demonstrate that the core of the successful use of digital health implementation relates to the transformational leadership and organized change management practices. Nevertheless, they have a significant indirect effect on the digital healthcare performance, and this effect happens due to effective knowledge transfer mechanisms. Knowledge transfer can assist healthcare professionals to gain, exchange and implement digital competencies which creates a process of embedding digital tools into common clinical and organisational practice. This review finds that digital healthcare performance is the product of the synergy between leadership, change management, and knowledge transfer instead of technology. The implications that these findings could have on healthcare leaders and policymakers are significant, and the change management and organizational learning institutionalization must be put into place with the digital health strategies in ingrained in order to create sustainability in improvement of performance.