Background: The mental foramen (MF) and accessory mental foramen (AMF) are the strategically important landmarks during surgical interventions and anaesthetic nerve blocks procedures involving the mental nerve. Mental foramen is known as the ventage of the mandible and is an important mark of the face for carrying out many diagnostics and surgical processes along with anesthetic procedures of the face. Thus, the present study is designed with an aim to get insight knowledge of position and shape of mental foramen in dry adult human mandible. Methods: Totally, 45 bones were studied in 2 years duration. The study was carried out in the Department of Anatomy of Ayaan Institute of Medical Sciences. The position of mental foramen was studied using an instrument known as digital Vernier Caliper (in mm) while shape was analyzed visually. Position of mental foramen was calculated using Statistical package for social sciences (SPSS) software. Results: The present study showed that the position of mental foramen from symphysis menti and posterior border of ramus of mandible was more from right side than left side and found to be insignificant while position of mental foramen from inferior border of body of mandible was more from left side than right side and found to be insignificant for right side while significant for left side. The shape of mental foramen from right side was found to be (Oval shape – 62.3% and round shape – 37.77%) while for left side (Oval shape–68.8% and round shape – 31.1%). Conclusions: Hence, mental foramen plays a pivotal role in performing major facial surgeries and is an important landmark for several facial procedures performed.

Rapid technological advancements in the last few decades have given rise to various new products and fields, such as cryptocurrencies, social media and sentiment analysis. The massive surge in internet usage has caused organizations and investors to increasingly base their decisions on content placed on social media platforms which are flooded with data from its users. One of those platforms is twitter, a micro-blogging platform which allows people to share their opinions in a limited number of characters. Certain users on these platforms have the ability to influence other users’ decision making, including investing. Although stock market prediction through sentiment analysis has been researched often, the amount of research done on prediction Bitcoin prices is relatively low. Furthermore, there is a gap in existing research in which samples are not limited to users that have more knowledge than individual investors. This paper uses sentiment analysis on tweets made be cryptocurrency influencers to see whether they can be used to predict Bitcoin price fluctuations. This paper, additionally researches differences in predictive capabilities between regions and differences in predictive capabilities between a bear and a bull market. The results in indicate that tweets made by cryptocurrency influencers contain statistically significant information about the future value of bitcoin. Thus, analyzing those tweets to exploit profitable opportunities can be worthwhile.

This research aim is to examine and analyze pre-trial implementation of delegation and trial of main cases based on Law Number 8 of 1981 concerning Criminal Procedure Law in Indonesia currently and How to reconstruct the policy formulation of the pre-trial decision on the delegation and trial of the main case in an effort to maximize the pre-trial function in the criminal justice system in Indonesia in accordance with the value of justice? this research uses the method of empirical juridical approach where The data used in this study are primary data and secondary data, using qualitative analysis. The results showed that the Problems that arise in the pre-trial implementation of the delegation and trial of the main case based on Law Number 8 of 1981 cannot be applied because in Article 156 paragraph (1) the Court is not authorized to hear the case, or the indictment cannot be accepted, or the indictment must be annulled, or pre-trial has been granted regarding legal or Whether or not arrest, detention, termination of investigation or prosecution, compensation and or rehabilitation for a person whose criminal case is terminated at the level of investigation or prosecution, and whether or not the determination of a suspect is valid therefore, The reconstruction of the policy formulation of the decision of the Pre-Trial against the delegation and trial of the main case is by adding a sentence (phrase) so that in order to uphold justice and legal certainty the judge has a legal basis or reason for accepting objections or the exception of the accused or his legal adviser.

Background: In stroke scenario, decreased hemoglobin levels have the potential to worsen brain ischemia; however, the association between the levels of hemoglobin with stroke mortality is not well understood. Aim: The study investigated the association of hemoglobin levels with 28 days mortality rate after ischemic stroke (IS). Methods: This was a retrospective study, where data of 74 patients admitted to ICU was collected with a diagnosis of stroke .The data were analyzed in the terms of demographic details, plasma glucose, HbA1c and hemoglobin levels. Results: Among 74 analyzed patients, 56.70% were men and 43.30% were females. In our study 32.4 % of stroke patients had anemia. Out of 45.9% non survivors, 21.6% stroke patients had hemoglobin level less than 11mg/ dl and 24.30% stroke patients had hemoglobin level more than 11mg/dl. Out of 54.1% survivors ,10.8.% and 43.20% stroke patients had hemoglobin level less than 11mg/ dl and more than 11mg/dl, respectively .The data was statistically significant. Conclusion: In conclusion, we showed that a significant proportion of stroke patients have low hemoglobin at the time of stroke onset and this is associated with increased mortality up to 28 days. Targeted interventions in this patient population may improve outcomes and require further evaluation.

Life of a parents with a child who agonizes from mental illness can be perplexing subsequently they need to have better understanding about the way their child’s mental illness presents itself in every life setting, this understanding may provide the foundation for seeking the treatment. Parental opinion and beliefs toward psychotropic drug compliance has a critical value that could improve or worse the course of treatment and the child’s mental health outcome. Aim: This study was conducted to assess the parental opinion and beliefs toward use of psychotropic drugs for treatment of mental health problems in children in the central region of the Kingdom of Saudi Arabia. Methods: A descriptive correlation cross section research design was utilized on a sample of 526 Saudi parents who were selected by a random location methodology. Data was collected using two part questionnaire, part one was the demographic data sheet, second part was a modified translated Arabic 16 item scale “parental opinion and beliefs toward use of psychotropic drugs for treatment of mental health problems in children.” Description about the purpose and nature of the study was explained to each individual potential participant. Participants were assured confidentiality of the collected data and that it will be used only by the researchers for the purpose of the current study. Data were analyzed using SPSS version 22. Results: Study revealed that half of the parents believed that some psychotropic drugs are dangerous for children. The total participants’ responses to the parental opinion and beliefs toward use of psychotropic drugs for treatment of mental health problems in children scale score ranged between 16 and 60 with higher scores indicating more accurate opinions and more favorable beliefs toward psychotropic medication prescription and administration to children. Correlation between selected demographic variables and parental opinion and beliefs toward use of psychotropic drugs for treatment of mental health problems in children, showed a highly statistically significant relationship between parents’ opinions and beliefs scores and the age of the parents, furthermore study findings revealed a highly statistically significant difference in the total opinion and beliefs score between participants with different marital status. Conclusion: Fear of psychiatric stigmatization and ignorance of the nature of mental disorders are important factors which influence the opinion and beliefs about psychotropic medication among parents of children with mental disorders,which threatens to rule out psychopharmacotherapy.The study findings showed the need for more education on scientific knowledge regarding the psychiatric treatment methods and its importance in managing psychiatric disorders among children.

Background: The management of prostate cancer may be difficult due to apoptosis resistance. HIF-1α (Hypoxia inducible factor 1α) and CypA (cyclophilin A) over expression promotes this resistance. Caspase 3 is a central executioner of the apoptosis pathway. Changed expression may correspond to tumor cell challenge. Aim: Evaluation of HIF-1α, CypA and Caspase 3 expressions in BPH (benign prostatic hyperplasia), PIN (prostatic intra-epithelial neoplasia) and PCa (prostatic carcinoma). Methods: One hundred four patients with histologically diagnosed prostatic carcinoma, 20 cases with BPH and 24 cases with PIN were investigated. Immunohistochemical assessment was executed to evaluate HIF-1α, CypA and Caspase 3 expressions. Results: In BPH cases, HIF-1α, CypA and Caspase 3 were expressed in 20%, 30% and 60% respectively. In PIN cases, HIF-1α, CypA and Caspase 3 were expressed in 33.3%, 41.7% and 41.7%, respectively while in PCa cases, HIF-1α, CypA and Caspase 3 were expressed in 57.7%, 69.2% and 25% respectively. Increasing stage of prostatic cancer showed a significant increased HIF-1α and CypA immuno-expression with lost caspase 3 immuno-expressions. Conclusions: Distorted HIF-1α, CypA and Caspase 3 expressions may act as a further mechanism of apoptotic resistance in prostatic carcinoma treatment.

This research examined 12 factors most associated with and predictive of corporate strategy execution in the United Arab Emirates’ steel manufacturing industry. It embraced a positivism research philosophy and quantitative methodology through respondent surveys (n = 112) and a case study (n = 80). Correlations between data sets were calculated using Pearson and Spearman correlation and multiple regression; t-tests, ANOVA, and Tukey–Kramer post-hoc statistical tests were also used. Participants perceived their organization’s strategy as being of high quality, with a statistical significance level (t [111] = 21.50; p < .001). Participants were satisfied with their organization’s strategy execution, with a statistical significance level (t [111] = 18.62; p < .001). Of the 12 factors, three represented statistically significant predictors (p < .05) of the perceived efficacy of strategy execution: clear guidelines, harmony between the execution plan and the power structure, and the organization’s ability to adapt to change. Hypothesis testing found that the higher the hierarchy level, the higher the number of respondents who strongly agreed with the survey questions related to the 12 elements. Organizations need to define power bases and form coalitions with those in power; focus on value-added, measurable results; and ensure that resources are fairly distributed. Furthermore, organizations need to assess the size of the strategic change and the time needed to execute it, outline the steps and tactics, clearly identify responsibilities and accountabilities, and overcome resistance to change, including cultural change.

Human nutrition is the process by which substances in food are transformed into body tissues and provide energy for the full range of physical and mental activities that make up human life. Antioxidants that usually taken through diet and have an important role in inhibition of stress due to oxidation that reason for beginning and development of numerous diseases such as cancer, and much other disease such as diabetes and also inflammation. There are certain gaps in literature about the different activities in compounds that exhibit functions in vegetables and fruits. Different free radical leads to oxidative stress to the particular cell and ultimately causes the cancer. The natural phenolic compounds have received increasing interest in the last years, since a great amount of them can be found in plants and consumption of vegetables and beverages with a high level of such compounds may reduce the risk of development of several diseases due to their antioxidant power, among other factors. Kaempferol as one of the flavonoids that main function involved in binding with cells of the cancer and ultimately kills the cancer cells. Anthocyanin mainly the type of the major compound in the outer portion of the skin of the onions The colour of the red showing the activities against the free radicals depending on the type as well as the nature of the chemical compound. Quercetin as the valuable type of the flavonoids that have been used in the purpose of the preventing diseases associated with the bacteria as well as the viruses. Different free radical leads to oxidative stress to the particular cell and ultimately causes the cancer.

The burden of infectious diseases by bacteria and fungi had constituted a great concern to the entire human population. Calliandra portoricensis (Fabaceae) had been widely used over the years in ethnomedicine for the; treatment of various ailments such as swollen gum, tooth and throat inflammation often associated with microbial infections. At present, no active antimicrobial compound has been reported from this specie. The aim of this research was to identify, isolate and characterize the antimicrobial compounds from the root of C. portoricensis. The pulverized root sample (0.8 Kg) was extracted by successive cold maceration respectively for 72 hr.. The most bioactive ethyl acetate extract (4.61 gm) was subjected to chromatographic column fractionation (Silica Gel G, 200-400 mesh-stationary phase). Gradient mixtures of n-hexane: ethyl acetate: methanol (4:0:0; 3:1:0; 2:2:0; 1:3:0; 0:1:0; 0:3:1; 0:2:2; 0:1:3; 0:0:4; – v/v/v) were used for elution. Agar well diffusion method was adopted for the bioassays susceptibility tests and MIC determinations. Clinically viable human pathogens for the tests were; Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Klebsiella pneumonia, Streptococus fecalis, Candida albicans and Aspergillus niger. Two major fractions (FA and FB) active against the test organisms were pooled The more active fraction FB on further purification by preparative TLC (Silica Gel G, 0.5 mm thickness), yielded bioactive pure commands C1 (9 mg) and C2 (8 mg). Both compounds exhibited MIC values of 125.00±0.70 µg per ml against Candida albicans and Aspergillus niger These activities were found to be quite significant with respect to the reference controls (Ciprofloxacin and fluconazole) at P < 0.05. Characterization of C1 and C2 by spectroscopic analysis (UV, MS, FT – IR and NMR), identified two novel compounds as Cassane - type tricyclic diterpenoids. C1 (Molecular Mass: 324, C20 H36 O3) is (5,10- 8,9- 12,13)-seco- 4,4,10 – trimethyl, 14 – hydroxymethyl, 16 – keto, 13(15) – ene – cassane furanoditerpene and compound C2 (Molecular Mass: 418, C24 H34 O6) is (12,13) – seco - 12, 14 – epoxy, 12(16) -Oxo –,13(15), 16(17) – diene, 4, 10, 17 – trimethyl, 4, 7 – di – aceto cassanoate. Similar Cassane - type diterpenoids have been reported for promising antimicrobial properties.

Background: Caesarean section has become the most performed major operation in obstetrics. The increasing rate of primary caesareans section becomes high worldwide due to early detection of fetal and maternal complications. Repeated caesarean section is one of the major contributory factors for increasing this rate very significantly. Now a day, vaginal delivery of pregnant mothers with the history of previous one caesarean with non-recurrent cause was established. It has been shown that the outcome of trial of labor in past caesarean delivery is acceptable, effective and safe for both mother and fetus, if the women are properly selected. Objective: The objectives of this study was to determine the outcomes of vaginal birth after caesarean section (VBAC) in case of previous one caesarean section to reduce the subsequence cesarean section with its complication. Materials and Methods: It was a cross sectional study carried out in the Maternity Unite-1, Department of Gynecology & Obstetrics, Sir Salimullah Medical College and Mitford hospital, Dhaka, Bangladesh, held on January 2010 to December 2010. Out of total 380 admitted pregnant women who had previous one caesarean section, 50 pregnant women of 37-42 weeks of gestational age with the history of one caesarean delivery with alive baby were selected as study population following consecutive and purposive sampling method. Patients with spontaneous onset labor but preterm pregnancy with any contraindication or prior caesarean section due to recurrent causes, history of classical caesarean section, more than one caesarean section, multiple pregnancy, pregnancy with medical disorder were excluded in the study. Results: Out of total 50 sampled pregnant women, vaginal delivery were done 16(32%) & emergency cesarean section were done 34(68%). According to the age group both vaginal & cesarean section 20-30 years were predominant, which were 8(50%) and 17(50%) respectively. Regarding antenatal care 13(81.25%) of vaginal delivery cases were regular. On the other hand, only 10(29.41%) of cesarean section were regular in care. Fetal survival outcome in vaginal & caesarean which were 14(87.5%) and 33(97.05%) respectively. Comparing the maternal complication maximum number of vaginal delivery group had no complications. Conclusion: In this study 14.5% pregnant women went spontaneous labor. By permitting a trial of labor in our pregnant mother with a previous caesarean section, we will be able to reduce the caesarean delivery rate. Women for VBAC needs regular antenatal checkup, timely admit in hospital and delivery under close supervision. Therefore, all pregnant women with prior delivery by caesarean section need not necessarily be delivered by caesarean section during the next pregnancy of a pregnant women.

Background: Asthma still the mainly prevalence chronic respiratory disease affecting individuals in different ages. The objective of this study was to find out the prevalence of asthma, and its triggering factors among medical students in the College of Medicine University of Hai'l city, Saudi Arabia. Methodology: The study investigated 198 students using online questionnaire. Results: The 198 male medical studentsaged between 20 -27 years with mean age of 21.5. The overall prevalence of asthma in in the medical students at the College of Medicine University of Hai'l was 10%.Regarding to things that aggravates asthma symptomsdust 5/20(25%), smoke 2/20(10%), dust+smoke 4/20(20%), dust+stress 1/20(5%), dust+smoke+stress+animals 2/20(10%), dust+smoke+cold weather 3/2(15%), dust+animal+stress 1/20(5%) and dust+coldweather+animals 2/20(10%). Conclusion: The prevalence of asthma in medical students is relatively high compared to global prevalence rates. The most common allergies triggering asthma symptoms in the college of Medicine, university of Hail, are dust, smoking, Animals and stress.

The phosphate solubilizing bacteria are soil microbe can dissolve P which is not available to become available to plants. They have capable to produce extracelluler enzyme, i.e. group of phosphatase enzyme which able to mineralized of organic P to inorganic P. The objective of this experiment was to examine compatibility test, phosphatase enzyme activity and phosphate solubility by phosphate solubilizing bacteria. The compatibility test was conducted qualitatively with the streak method. The design for bioassay of phosphate solubilizing phosphate for phosphatase activity test and P solubility was a randomized block design with five treatments and five replications. The phosphate solubilizing bacteria used were Burkolderia sp., Pseudomonas mallei, Bacillus substilis, and Bacillus megatherium. The results of the compatibility test on the phosphate solubilizing bacterial isolates showed that each isolate was compatible. Furthermore, the result of experiment revealed that phosphate solubilizing bacteria could produce phosphatase enzyme ranges between 4,53-4,82 µg pNP/g/h and P dissolved about 3909,55-6052,19 ppm. These phosphate solubilizing bacteria can be used as biofertilizers to increase soil P solubility.

This research aim is to examine and analyze the weaknesses of the implementation of the auction execution of the object of the Mortgage especially in determining the auction price which is not yet based on Justice Value to then create a reconstruction of the execution auction of the Guarantee Rights in determining the auction price based on justice value. This research uses the method of empirical juridical approach where the data used in this study are primary data and secondary data, using qualitative analysis. The results showed that the weaknesses can be seen in Law no. 4 of 1996 concerning Mortgage Rights on Land and Objects Related to Land and Article 43 and Article 44 of the Minister of Finance Regulation No.27 / PMK.06 / 2016 concerning the Implementation Guidelines for Auction in determining the limit value made by an independent appraiser is in fact without any supervision by the supervisory agency for that and also without clear regulations regarding how to determine the auction price / auction limit value. To be able to resolve this, it is necessary to reconstruct the execution of the guarantee of the Guarantee Rights in determining the auction price based on Justice Value, namely in Article 6 and Article 20 paragraph (2) of Law No. 4 of 1996 concerning Mortgage Rights for Land and Objects Related to Land and Article 43 and Article 44 of the Minister of Finance Regulation No. the debtor and the creditor and if the auction price is not agreed upon, the settlement regarding the determination of the auction price shall be settled through the court so that the determination of the auction price can met the justice value.

Program Evaluation is the systematic gathering of information for purposes of making decisions. After the development and establishment of e learning program, Pak Red Crescent Medical & Dental College (PRCM&DC) were made with the help of the Medical Education Department a program evaluation questionnaire based on all frequently asked questions send to all students by e evaluation form. All the students who have The Students who have internet facility and attend the classes regularly are included. Student’s response rate is 34.88%. Reliability coefficient of the questionnaire is 0.822. Majority of the students found the clear objectives of the subject and interactive teaching decrease the anxity. Students were satisfied with learning material which is provided by the facilitators like lesson plans, course notes, handouts books and important notes are very helpful. Many students agreed that they were encouraged to asked questions and give answers during lectures, and most of them were satisfied with the delivery and pace of lecture. Majority of the students were satisfied with the present teaching through e learning method. They were well understood the teaching and learning material and also were appreciate the organization of the thought material.

Advances in technology, information and communication make it easy for citizen, especially in Indonesia to find and disseminate information on the spread of Corona Virus Disease 2019 (Covid-19), especially the emergence of the citizen journalism movement that has found a "new life", ordinary people, not journalists, it can create news and distribute it globally. Media company provides oppurtunity to broadcast and publish the news and the information derived from citizen journalism. The existence of citizen journalism has changed the role of the public, which has been the object of news or audience, to become like the professional journalist. Journalistic activity by the citizen journalism in the situation of the spread of the Corona Virus Disease 2019 (Covid-19) pandemic, it must receive legal protection as the guarantee for citizens in spreading truthful information for the public interest.