Vagina is a part of the female genital tract leading from external genitals to the cervix of the uterus. It is a muscular and an elastic organ. There are various malformations that can occur in the female genital organ, one among them being Mullerian Agenesis. Mullerian agenesis/ MRKH syndrome is a congenital anomaly in females due to the developmental failure of vagina from the mullerian duct. This results in aplasia of the uterus/ vagina or presence of rudimentary uterus and upper part of the vagina.1 It is the most common cause of primary amenorrhea. Women with vaginal agenesis usually suffer from mental depression and they are deprived of a normal social life. It is mandatory to educate and motivate the patients and their family about the various treatment options available and carry out the treatment which is best suited according to the patient’s needs. The most common treatment modalities include non-surgical methods, surgical methods or combination of both. Surgical creation of neovagina along with the use of a neovaginal prosthesis can go a long way in improving the quality of life of the patient. This article presents a case report of a young woman with MRKH syndrome who was referred to the Department of Prosthodontics for fabrication of a neovaginal prosthesis which was to be used after surgery to maintain a patent passage. The neovaginal prosthesis was fabricated by a Maxillofacial Prosthodontist using autopolymerizing acrylic resin.

Obesity is a chronic condition characterized by excess body fat which results in an increase in the body weight of patients. C acutangula is a medicinal plant used in traditional medicine in Burkina Faso for the management of weight gain. The objective of this study was to determine the anti obesity potential of the bioactive fractions of C. acutangula extract. The ethanolic extract of C. acutangula was fractionated to obtain the hexanic, dichloromethane, ethyl acetate, butanol and aqueous fractions. The effect of these fractions on weight gain, food intake and lipid biochemical parameters were determined in vivo. The inhibitory activity of digestive enzymes (pancreatic lipase, trypsin) and the antioxidant potential were evaluated for these fractions. The butanolic fraction showed the best activity with an inhibition of 68.20 ± 3.4% at 100 μg / ml. The ethyl acetate fraction gave the best activity on reducing body weight with 18.11% reduction to 50mg / kg of body weight against the control (hyperlipid diet) which gave increases in weight of 34.83% respectively. The ethyl acetate fraction at 25 and 75 mg / kg of body weight and the butanolic fraction at 50 mg / kg showed the best reductions in the triglyceride level with respectively 111.89 ± 28.6; 108.35 ± 10.5 and 108.9 ± 10.21 mg / dl against the control which gave a rate of 280 ± 8.43 mg / dl. Best activities on cholesterol levels, HDLc and LDLc have been observed. For the antioxidant effect, the fractions caused a reduction in the level of MDA and an induction of the production of catalase. These results demonstrate that the ethyl acetate and butanolic fractions contain antiobesity molecules and could therefore be used in the implementation of a phytomedicine.

L’observation de la pratique de classe et l’analyse didactique des programmes et des manuels de français d’avant l’introduction du curriculum basé sur les compétences au Rwanda, montre que la didactique de la grammaire de français suivait une démarche déductive qui met au centre de tout enseignement l’enseignant, le rôle de l’apprenant relégué au second plan. L’an 2008 fait que le français passe de la langue d’instruction à la langue objet d’enseignement, supplantée par l’anglais. L’intérêt d’apprendre et d’enseigner cette langue va sensiblement régresser. Aujourd’hui, pour relever l’enseignement efficace du français et de la grammaire en particulier, les efforts doivent converger vers l’intégration et la pratique des nouvelles démarches de la didactique de la grammaire. Leur coexistence n’y est pas pour rien car la résistance au changement persiste suite au degré de connaissance et d’utilisation de ces démarches et à l’attitude des enseignants et des apprenants face à la situation nouvelle. Notre recherche à la fois qualitative et quantitative, avait pour objectif de présenter la situation actuelle de la didactique de la grammaire du FLE dans les écoles secondaires au Rwanda, en vue de proposer une meilleure pratique de ses démarches. Elle a focalisé sur les élèves de la 2ème et de la5ème année, et leurs enseignants des six écoles sélectionnées du district de Kayonza au Rwanda. Leurs réponses au questionnaire et à l’entretien ont prouvé que l’enseignement de la grammaire du FLE dans ces écoles reste traditionnelle et déductive .Les démarches inductives et active de découverte sont quasiment inconnues et rarement utilisées, d’où la nécessité d’une formation et une pratique de ces nouvelles démarches pour une didactique efficace de la grammaire en particulier et du français en général.

Mobile telecommunication and information technology is of utmost important in our social life, the economy, business transactions and education among others. Regrettably, the interacting innovations in products, services and technologies with a general convergence or blurring of distinctions between platforms, products and services has created enormous impacts as well as benefits in the mobile telephony sector. This paper therefore, seeks to examine these impacts and benefits of mobile telecommunications sector in Cameroon. In order to attain the above objectives, we employed content analysis in this regard. This paper therefore, conclude with some robust recommendations which if effectively implemented, will go a long way to improve on the mobile telecommunication sector as a result, enhance the digital economy of Cameroon.

The public space in the city is the platform for the manifestation of cultural values. Locating and improving the quality of these spaces creates interaction between citizens and space. In the meantime, identifying and classifying the main spatial qualities under the title of Art Street is an effective step to locate and improve the quality of urban spaces. Such a street is organized with the focus on art and provides the possibility of two-way communication between people and art, or in other words, urban interactive art (public art). The result is the role of citizens as creators of Art works and increasing their belonging to the environment. The present study seeks to achieve the qualitative components affecting the locating of Art Street and tries to interpret the concept of street art, physical, social and perceptual criteria for the locating and organizing of Art Street. For this purpose, by studying the relevant theoretical foundations, the components and criteria of Art Street were collected and classified from the perspective of experts. From their viewpoint the components of environmental quality affecting the desirability of Art Street are classified into four dimensions: physical, traffic, socio-cultural and environmental. In the next step, based on theoretical foundations, a questionnaire was distributed among the citizens in three selected sequences, including a part of the three axes of Valiasr Street, Enghelab and North Kargar street and the qualitative dimensions and locating criteria of Art Street were extracted from their point of view and classified Then, a comparative comparison of the locating criteria of Art Street from the perspective of citizens and experts was performed. According to the research findings, the criterion for the existence of uses related to art and leisure and the continuity and flexibility of sidewalks is one of the main criteria for locating Art Street. the presence of activists such as artists and art students and functions such as art galleries, colleges and art and craft markets is the main factor in the successful location of Art Street. Also, the physical integration in the components, the cohesion of functional nodes, and the ability to diversity and fluidity of functions are the main criteria representing Art Street.

Capital Punishment for illegal narcotics traffickers is indeed needed to reduce the crime in the community, even though the polemic in the enforcement of this punishment still arises because it is closely related to human rights enforcement. This research intends to examine weaknesses in the imposition of Capital Punishment based the view of Pancasila philosophy as well as the ideal construction of the Capital Punishment regulation in narcotics and psychotropic offenses based on Pancasila values. The type of writing used in this research is normative legal research method. The method of normative legal research is legal research that places law as a norm system building. The results show that capital punishment can be accounted for in the Pancasila state which is manifested as individual protection as well as protecting society for the creation of justice and legal truth based on the almighty God. The Capital Punishment, from the perspective of Pancasila, is seen as one unity. Pancasila must be the basis for seeing the Capital Punishment as In its implementation, the Capital Punishment for narcotics and psychotropic offenses still has weaknesses therefore it need an ideal construction of the regulation of the Capital Punishment in narcotics and psychotropic offenses based on the values of Pancasila is carried out with due regard to the main crime. With this reconstruction, The Capital Punishment will be a special punishment that can be applied carefully, selectively and specifically in dangerous cases as it must be determined unanimously by the panel of judges first.

The paper represents the challenges of Georgia’s capital market, its importance for economic development and diversification of the financial sector. Capital markets have an increasing role and weight in Georgia’s economy. The formation of the capital market is a long process as it requires the formation of the financial instruments, market infrastructure and institutions. Considering the capacity of economy and its potential benefits, Georgia has less developed economy and therefore, the capital market is underdeveloped. The paper analyzes the prerequisites for forming and developing the capital market in Georgia, as well as its characteristics. In this paper we investigate the several sources for financing gross financial needs and for making optimal decision, which type of instrument should the government of Georgia use before raising funds, we compare the financial conditions of the existing sources with each other.

A company increases profits every year in order to keep reaching a larger target. It can be reached if each employee is having an Organizational Citizenship Behavior (OCB). The aims of this study are to measure and analyze the influence of job satisfaction, Perceived Organizational Support (POS), and organizational climate through OCB of the employee on employees in an outsourcing company Jakarta. The population of this study was all employees in the outsourcing company, which were 72 respondents. The sampling technique used in this study was saturated sampling with all employees for the object. This study used a linear regression method to analyze data. The finding of this study was job satisfaction, POS, and organizational climate variables have significant correlations to OCB. This study also showed the most variable that influencing OCB was job satisfaction.

Currently, maintaining good hygiene and sanitization as a precautionary measure is of importance to avoid the spread of the novel Coronavirus. As a part of prophylaxis during the COVID pandemic, hand sanitizing gel was formulated in Riyadh Municipality Central Area Laboratories based on WHO guidelines. The gel was evaluated by physical, chemical and microbiological testing and compared with five commercially available hand sanitizers in Riyadh City. The results revealed that the laboratory formulated gel has a pH of 6.0 and 80% ethanol vlv, with very strong antibacterial activity recorded in the range of 20.1 to 21.2 mm against five selected bacterial strains with highest activity against E.coli ATCC 25922. The minimum inhibitory and minimum bactericidal concentration was observed to be 12.5% and the gel was able to kill the bacterial flora on volunteers hand by a Mean cfu reduction of 99.24% in 30 seconds. The results obtained in this study demonstrate that laboratory formulated gel is highly effective than 5 commercial brands against all the bacterial strains tested.

Nutrient canals are radiolucencies seen in the alveolar bone which are considered to be the channels that contain blood vessels and nerves supplying the teeth and the supporting structures. They are also called as circulating canals, interdental channels and vascular canals. They are predominantly seen on the intraoral periapical radiographs in the mandibular anterior region. Though they are considered to be normal, according to literature, some investigators have correlated the radiographic appearance of nutrient canals with certain pathologic conditions. Hence this study was undertaken to rule out the association as well as prevalence of nutrient canals in patients with systemic conditions like hypertension and diabetes.

The Constitution of India is established upon the fundamental guideline of Rule of Law which in itself incorporates quality of Law. What's more, the Preamble to the Constitution depicts the thought where Justice, Freedom and Equality is to be made sure about to all the residents and Fraternity must be advanced among all the residents. However, it has been a long time since the Constitution was ordered and we have neglected to guarantee that they are being followed. The term 'We' incorporates the Legislature, Executive and Judiciary yet additionally the nation all in all. Crowd Violence is one of such territories where standards cherished in the Constitution are disregarded. In this article, the writers give a short review about the reasons related with crowd brutality, the current law in this regard and the location a significant issue of whether an explicit law is required. In this examination paper, I would concentrate on the current legitimate arrangements concerning savagery, the issues with these arrangements and requirement for extraordinary laws managing such viciousness with the assistance of doctrinal examination. I would likewise study the circumstance on different nations where such viciousness is pervasive and look at the techniques received by them to check such viciousness. I would likewise bring up the proposals made by the Supreme Court just as the bills presented by the Members of Parliament to check such viciousness.

Nowadays, although the technology keeps developing, the quantity of human resources who have competence and expertise in sharia economic continues to be minimum. It gives several direct impacts on sharia banking. One of the direct impacts is high turnover intention. The purpose of this study was to look at the Transformational Leadership effect, Perceived Organizational Support, and Workload on Turnover Intention in one of sharia banking in Jakarta. Samples of the study were employees who worked at one of sharia banking in Jakarta. Sampling was conducted using nonprobability techniques, which is purposive sampling with the Slovin formula of 101 people. This study was conducted quantitatively, and the analysis method used in this study was multiple linear regression analysis. The results of the study showed that transformational leadership, perceived organizational support and workload variables have a significant effect on turnover intention. The result of the study also showed that what affects turnover intention the most is workload. It was proven by the results of the simultaneous test (F test) and partial test (t-test) which showed the numerous value of three independent variables that supported the hypothesis.

Steven-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are potentially life-threatening mucocutaneous diseases characterized by hypersensitivity to medication and infections. Inspite of complete recovery from skin problems without sequelae, survivors can land with serious ocular complications culminating in blindness irrespective of intensive local and systemic therapy. We are describing the clinical course and treatment of a patient with TEN who developed bilateral ankyloblepharon after recovery from the acute attack. Amniotic membrane was applied to the ocular surface of the patient after correcting the ankyloblepharon. Amniotic membrane transplantation (AMT) has been proven to be an effective mode of treatment for severe ocular surface and eyelid inflammation as it decreases the risk of ocular and visual sequelae. Early detection of complications and aggressive treatment of the same are essential for preservation of vision.

Malaria is a life-threatening disease with high mortality and prevalence especially in children under the age of 5. Herbal remedies like Nauclea latifolia have been used and found to be effective in the treatment of malaria. However, presentations like decoctions, liquid extracts are not suitable particularly for children. Therefore, in this study, syrup formulations of the dried aqueous root extract of Nauclea latifolia (AREL) were developed using honey, simple syrup BP and water as vehicle in the presence and absence of a sweetener, thickener and preservatives. Organoleptic and physicochemical properties such as odor, color, taste, homogeneity, pH and density were evaluated. Stability of the syrups at room temperature, in the refrigerator and at accelerated temperature was also evaluated. In vivo anti-plasmodial activity of optimized syrup formulation was investigated according to standardized methods. Results show the syrups were brown to amber in color, homogenous and had sweet to bitter taste. The pH of the syrups were between 4.45 and 5.78, flow rate was between 0.00 and 2.17 g/sec. Density was between 1.24 and 1.41 g/mL; syrups containing honey were non-flowing while those formulated with simple syrup were more free-flowing. In vivo studies show that the optimized syrup formulation possess ability to inhibit parasitemia. No observable changes were noticed after the period of storage. This study shows that the development of the dried aqueous root extract of Nauclea latifolia into syrups as a standardized dosage form capable of inhibiting parasitemia could be explored.

Medicinal plants are source of a great economic value. Plants herbs are naturally gifted at the synthesis of medicinal compounds. The extraction and characterization of bioactive compounds from medicinal plants have resulted in the discovery of new drugs with high therapeutic value. Baobab Adansonia digitata L., (Malvaceae) seeds were collected from El-Obeid, North Kordofan state Sudan, and were extracted with hexane as solvent the extracted oil was analyzed by GC-MS. Twenty four constituents were detected the major constituents are: 9-octadecanoic acid methyl ester (25.08), 9,12-Octadecadienoic acid (Z,Z)-, methyl ester (23.08), Hexadecanoic acid, methyl ester (22.78), Methyl stearate (6.86) and Methyl 2-octylcyclopropene-1-heptanoate (6.08). In the well diffusion bioassay the oil showed significant activity against Bacillus subtilis, Pseudomonas aeroginosa, Staphylococcus aureus, and the yeast Candida albicans but it was partially active against Escherichia coli. The antioxidant activity of the extracted oil was evaluated using the standard 2, 2diphenyl-1-picrylhydrazyl (DPPH) 0.5 ml. The antioxidant activity of the extracted oil was 19.00 ± 0.08