Background: One of the leading causes of cancer-related death in women worldwide, that causes an enhancednegative impact on quality of life with regard to social and economic burden, is Cervical cancer (CaCx). Early diagnosis and treatment can plummetassociated mortality and morbidity, by hit hard and early approach. Aim and objective: To estimate serum total antioxidant capacity (TAC), and malondialdehyde (MDA) in CaCx patients and analyse their response to chemoradiation. Materials and Methods: Histopathologically proven CaCx patients (n=50) and age-matched healthy females (n=50) were recruited in case-control study. Estimation of Serum TAC, and MDA was done in recruited subjects. Both of these parameters wasestimated again after chemoradiationin CaCx patients, to scrutinize the effect of chemoradiation. In addition, 84% controls and 34% cervical cancer patients had a history of Vit. C and E supplementation. Results: The mean +SD age of the patients and controls was 43.98±6.38 and 31.56±6.84 years, respectively. The mean level of serum MDA in the patients was significantly higher as compared with the controls, whereas the mean TAC in the patients was reduced in same comparison. After chemoradiation, serum levels of TAC and MDA, increased and decreased, respectively. Conclusion: These analytical data captured suggests that patients with CaCx were in oxidative stress because the chosen oxidative parameters, serum MDA were increased, and the defensive TAC was decreased in them. Chemoradiotherapy improved their antioxidant capacity. Further studies are needed to evaluate the concurrent use of antioxidants with chemoradiotherapy for improving the disease prognosis.

A study was undertaken to develop and apply the first-order Markov model in generating the synthetic stream flow for Adada, Ivo, Otamiri, Imo and Ajali rivers located in South East Nigeria. The best-fit probability distributions for the maximum annual stream flows were lognormal, Weibull, normal and lognormal for Adada, Ajali, Ivo, Otamiri and Imo (Umuokpara) rivers respectively were used in simulating the associated random deviates. The stream flow data for 10 years (1980 to 1989) were used to develop the model and to predict the stream flow. The model performance was evaluated with the aid of the coefficient of determination (R2). The results indicated a satisfactory performance as evidenced by R2 values of 51.69%, 31.3%, 21.4%, 33% and 21% for Adada, Ajali, Ivo, Otamiri and Imo rivers respectively. The developed models were used to generate 50-year synthetic stream flows of these rivers. The study showed that the annual Markov models have proved to be a powerful tool to extend 10-year record of maximum annual runoffs.

Basketball has become one of the most popular international sports in which a successful game outcome is highly contingent upon optimal shooting performance. The purpose of this case study was to quantify and examine the kinematic changes in shooting motion as a player progresses from mid-range 2-point shots to beyond the 3-point line. One former collegiate basketball player performed 50 mid-range 2-point (5.20m) and 50 3-point (6.75m) shots divided into 10 sets separated by 1-2-minute rest intervals. Two high-definition cameras recording at 30 fps positioned perpendicular to the subject’s sagittal plane of motion were used for data collection. The first camera positioned 10 m away was used to capture body kinematics, while the second camera positioned 15 m away was used to capture the trajectory data. The kinematic variables captured at the initial phase of the shooting motion (Phase1) were knee angle, hip angle, ankle angle, elbow height, shoulder angle, elbow angle, and basketball height and at the time point of ball release (Phase 2) were shoulder angle at release, heel height, basketball release height, trajectory height, and ball entry angle. The findings of this case study indicate that greater flexion in the knee joint during the Phase 1 and greater heel height indicating larger vertical displacement during the Phase 2 of the shooting motion were the main kinematic adjustments influenced by the increased shooting distance. Therefore, we may assume that these changes were made to achieve greater ground reaction forces to compensate for the increased distance from the rim.

Capitalization is one of the most essential conventions of writing in English. A proper use of capitalization not only signals the beginning of a sentence or highlights certain types of words in a sentence but also ensures the clarity of meaning and the effectiveness of writing. Unfortunately, many EFL learners fail to use it correctly in their writing that prevent them from developing their writing skills and eventually negatively affect their overall language learning process. The goal of the present study was to find out the most frequent capitalization errors made by the EFL learners at the undergraduate level. By using a survey sheet, the study conducted a survey among 230 undergraduate students at Bangladesh Agricultural University and found that the use of capital/small letters with certain words associated with the Internet like Net, Web, Internet, etc.; with the names of general academic subjects; with the family relationship words; with the exceptional proper nouns such as black & white (names of human race), sun & moon (names of planet); with the first word of an incomplete sentence after a colon; with the titles of people; etc. are some of the particular areas where the participants made most frequent errors. The study basically attempted to make the learners aware of their common capitalization errors, so that, they can minimize the errors in their writing, and can make their writing more accurate, meaningful, and comprehensible.

The purpose of this study was to determine the application of Total Quality. Management using the QC 7 Tools method at PT. XYZ. PT. Koito Indonesia is a company engaged in the manufacturing industry in the manufacture of lighting products. The analytical method used in this study is a quantitative method. PT. XYZ which has a very high Defect Rate in the Molding section. With a high Defect Rate situation in the Molding area it is necessary to reduce the high manufacturing defect so that it can improve the quality of the company measured in a Key Performance Indicator. Waste of defective products that occur in the Molding section is detrimental to the company and reduce the company's performance.

Staphylococcus aureus is one of the important pathogen often termed as superbug. After S. aureus interacting with host innate immune system, it induces the release of pro- inflammatory cytokines like TNF-α and IL-1β from Immune cells. In the current study, various strains of S. aureus and their cell wall lysates indicated cross reactivity with murine cytokines ELISA antibodies. In cell wall lysates of S. aureus, various proteins are involved in this cross reactivity phenomenon. This cross reactivity was exhibited in the form of unusual exaggerated signals while performing ELISA for quantification of murine cytokines. The proteins of cell wall lysates among various stains of S. aureus were determined using SDS-PAGE. To all of our data, it is revealed that unknown epitopes of S. aureus are involved in producing exaggerated signals of cytokines during their quantification by ELISA. This was generated not only during interaction of various strains of S. aureus with murine bone marrow derived macrophages (BMDM) but also in control settings where cell free system was used in ruling out this cross reactivity phenomenon.

Social and environmental responsibility is based on the presence of investment activities (the corporate) which not only has positive impacts but also negative impacts. The research an empirical-juridical research and examines directly several companies in Maluku Province, Indonesia. The data obtained were analyzed descriptively and qualitatively. The results show that the right of communities is a demand for fulfillment based on legal regulations as a form of responsibility for the obligations of the State or other parties for the interests of an association or association of people who have social interaction relations in a community area within a country. The local government through the surveillance authority guarantees the rights of the community to obtain sources of life so that they do not become lost due to company activities. This protection is through the authority of the local government to supervise CSR activities as the government’s responsibility for society and the environment.

The study investigated factors influencing E-learning in Tertiary Institutions in Rivers State, Nigeria. Three research questions guided the study. The study adopted a descriptive survey research design. A sample of 376 undergraduate students was drawn from the population of 3,660 students in the Faculty of Education of three tertiary institutions in Rivers State through proportionate stratified random sampling technique. An instrument titled E-learning Factors Influence Questionnaire (EFIQ) which was developed by the researchers was used for data collection. It contained 23 items which are in three sections of A-facilities, B-lecturer’s competencies, C-students attitude. The EFIQ was validated by experts in Educational Technology and Measurement and Evaluation based on face and construct validities. The reliability of the instrument EFIQ was established through Cronbach Alpha technique and the reliability coefficient obtained was 0.82. Data collected was analyzed using mean and standard deviation, and a criterion mean of 2.50 was used for judgement. The result revealed that facilities, lecturer’s competencies and attitude of students influence E-learning in tertiary institutions in Rivers State. Based on these results, recommendations were made including that students should endeavour to have positive attitude towards e-learning and the tertiary institutions should provide enough e-learning facilities which will aid the students in learning.

Ectopic Pregnancy, a life jeopardizing emergency, can land in disaster, if the diagnosis is missed. Any woman in the reproductive age group presenting with vaginal bleeding and abdominal pain- the first suspicion should be ectopic. This was a hospital based retrospective cohort study of 5 years in Haryana, North India (3 Tertiary Care Centres)- to evaluate the incidence, patient profile, high risk factors, clinical presentation, diagnostic methods, treatment, outcome and complications of the same. Statistical analysis was done by MS Excel spread sheet using SPSS software 19.0 version. A total of 175 cases of ectopic pregnancy were diagnosed during the study period (Incidence of 1.521%).Majority of the patients were in age group 21 to 30 years 101/175(57.71%) with nulliparous being 60/175(34.28%).Most important risk factors found were past history of miscarriage, pelvic surgery, tubal surgery and tubal ligation.75 % patients presented with the classical triad of lower abdominal pain, amenorrhoea, and bleeding per vaginum. Clinical diagnosis was possible in 85.71% while 11.4% patients were ultrasonographically diagnosed. 96.7 % were tubal ectopic gestations. Conservative expectant management was done in 2 patients, medical methotrexate therapy was given in 26 out of which 6 required surgery for failed therapy & 84 % were surgically managed. 54 % required blood transfusion and there were no deaths. We conclude that identifying common risk factors and being ectopic minded will help clinicians in diagnosing and managing ectopic pregnancy at the earliest to reduce morbidity and mortality associated with the condition.

Nowadays, the Geographic Information System (GIS) technology has become more popular and is now widely used in earth sciences and environmental. It is a huge and rapidly growing industry and market all over the world, with huge demand for knowledge, experience, information, data, and GIS software products. Project managers, environmental scientists, legislators, activists, and the public are curious about what is the technology of the GIS, and how it can help them with cases or projects. Professionals of GIS are interested in learning of basics of earth sciences and environmental to apply GIS technology in these sciences and other related disciplines. This paper start from the introduction about GIS and various applications, and these applications divided into Overlay of layers, Land Information, Utilities and Infrastructure, Environmental, Archaeology, Natural Hazards, Military, Oceanography, Water Resources, and Agriculture. Finally, we are trying to give conclusions about this research. This paper gives an overview of the application and uses related to GIS. GIS techniques are very useful for various kinds of applications such as for Education, Medical, Tourism and Archeology, Urban Planning, Temperature, water harvesting, Change Detection, and Business. So the use of GIS is the most interesting research topic in recent years.

This paper aims at the problems of low efficiency and poor quality of college students' online courses, and makes a questionnaire survey on the influencing factors of college students' online course learning quality. According to the survey results, the factors that affect the learning quality of college students' online courses are divided into four dimensions: platform design dimension, curriculum design dimension, students' self-management dimension and hardware support dimension. Through the analysis of the survey data, we can understand the present situation of college students' fragmented learning and get the factors that affect the quality of college students' fragmented learning, and finally put forward relevant strategies to improve the learning quality of college students' online courses.

This study aims to determine the analysis of changes in the cost recovery scheme against the gross split of oil and gas companies in the ETB field. Based on previous research, it can be seen that the comparative analysis of the Change in Cost Recovery Scheme to the Gross Split has found that the Gross Split Scheme is superior to the Cost Recovery Scheme. This study took the population and samples from PT Pertamina, the ETB Field subcontractor. These results indicate that Product Sharing Contract (PSC) Gross Split is considered to be superior compared to PSC Cost Recovery and is feasible to implement because this indicator shows a fairly good sensitivity.

Delirium is prevalent among critically ill patients and it is an independent risk factor for mortality. The audit aimed to determine the staff awareness of delirium screening and to establish whether we assess and document the cognitive state of our patients regularly in the course of intensive care admission. Furthermore, we aimed to review if the causes of delirium were considered and treated appropriately. A closed loop audit was conducted in the different intensive care units. The initial audit showed that Most of the nurses; 63 (97%) neither assessed the patients for delirium nor were aware of the delirium assessment checklist. There were 12(20%) patients out of 58 who had delirium during the audit with no documentation or treatment. The second audit cycle showed 86 (90.5%) of the staff were fully aware of the checklist and using it. We conclude that re-implementing the routine screening for delirium improved its evaluation and management.

This semi-systematic review aimed to quantitatively map and identify data gaps in patient journey touchpoints for chronic low back pain (CLBP) and osteoarthritis (OA) in Saudi Arabia. An evidence mapping approach was used to quantify the prevalence and distribution of different touch points including awareness, screening, diagnosis, treatment, adherence and control across CLBP and OA patient journeys. A systematic search of databases MEDLINE, Embase and BIOSIS was conducted using predefined inclusion criteria to identify relevant studies published in English between 01 January 2010 and 11 December 2019. A substantive unstructured literature search was also conducted on public or government websites with no date restriction. To address data gaps, anecdotal data were also considered for inclusion. Data combined from all sources was synthesized and presented as simple or weighted mean. Of the 47 records identified, five studies met the inclusion criteria. The overall prevalence of CLBP from three studies was estimated at 8%. The prevalence of OA as per anecdotal data was 30%. Awareness of OA, based on two published studies and anecdotal evidence was 48%. According to anecdotal evidence, screening and diagnosis of OA was 50% and 60%, respectively. The majority of patients with OA (80%) were treated, with higher adherence (90%), of which 60% of patients showed symptoms control. The study findings highlight the need for more evidence-based research related to common patient journey touchpoints, which in turn may aid in efficient resource utilization, innovative pain services and collaborative practices to improve patient outcomes at national level.

Mycetoma is a chronic, suppurative, granulomatous infection of subcutaneous tissue that eventually may involve bone. The Infection is caused by free living, exogenous, geophilic actinomycetes and fungi. It is characterized by a triad of localized swelling, underlying sinus tract and production of grains or granules. Approximately 40% of mycetomas worldwide are eumycotic and rest is actinomycotic [1]. Eumycetoma is most probably acquired by traumatic inoculation of certain fungi into subcutaneous tissue. Fungi are considered as an unusual cause of osteomyelitis of hand/palm. This paper describes a case of eumycetoma osteomyelitis of the hand. With clinical, radiological and pathological correlation we arrived at a final diagnosis.