The emergence and spread of bacterial resistance to antibiotics is a growing problem worldwide, which presents a significant threat to public health globally. The present study was designed to determine knowledge, attitude and practice of antibiotic use. A cross-sectional survey was performed using a questionnaire on a sample randomly selected from east Libya for pediatric doctors, pharmacies and parents. A total of 400 participating subjects were approached to be included in the study, 234 agreed to participate giving a response rate of 58.5%. The awareness of antimicrobial resistant was very high among the pharmacist and doctors responder (96.43%) (93.91%) respectively, in contrast participants parents (41.76%). More than one-third (37.36%) were self-medicated with antibiotics to treat mainly common cold and cough. The reasons of antibiotic misuse in the present study according to the opinion of participant doctors were an empirical use, incorrect dose and low level of education with 68.70%, 18. 26%, 13.04% respectively. Pharmacies are the major source of antibiotics reporting more than –quarter 28.57% were sold antibiotic without prescription. These findings presented aid in the assessment of the adequacy of present public educational campaigns to promote specific messages to rationalize antibiotic use, and compensate for knowledge and attitude gaps as an effort towards preventing development of antibiotic resistance.

Kikuchi-Fujimoto's disease or necrotizing histiocytic lymphadenitis is a rare benign disease, revealed by the presence of cervical lymphadenopathy in an inflammatory context. Reporting the case of a young patient whose diagnosis was only possible by the pathological study of the surgical specimen.

Plasma cell leukemia is one of the most aggressive and rarest forms of plasma cell dyscrasias. It can arise from a leukemic transformation of multiple myeloma or can be primary and the prognosis is very poor. We present the case of a 68 year old male who presented to our hospital with features of acute renal failure. He was diagnosed as a case of Plasma cell leukemia and was treated with chemotherapy. However his condition deteriorated and he died 2 weeks after diagnosis. The recommended treatment of plasma cell leukemia is aggressive chemotherapy followed by stem cell transplantation. However, once diagnosed, the prognosis is very poor.

Bangladesh is used to struggle with several natural disasters and has become one of the most earthquake vulnerable countries of the world. The nature and the distribution of the earthquake events in different seismic zones of Bangladesh are related to various man-made factors. This study is dealing with the impact of these factors which are leading to the incidence of earthquakes. Geographic information system (GIS) is used to analyze earthquake data graphically. Bivariate analysis is conducted using t-test approach for hypothesis testing purpose. Availability of gas and oil has been turned out as significant in the results on earthquake occurrences. Three Poisson regression models, along with bivariate analysis, are employed in this study to assess the occurrence of earthquakes in relation with having minerals in Bangladesh. The results give evidence that the presence of minerals is vulnerable to earthquake and production of minerals increases the vulnerability. The presence of gas and oil in the related districts significantly increases the expected number of earthquakes. Keeping similarity with this result, the districts where gas and oil production are running also experience significantly more frequency of earthquakes compared to that of other districts. It is also found from the analysis that the more amount of gas the districts have, the higher the expected number of earthquakes is in that districts. However, neither presence of coal nor running of coal production has any significant effect on earthquake occurrence.

Etymologically, melatonin (N-acetyl-5-methoxytryptamine) can be traced back to the origin of life. The first origin of melatonin was detected in cyano-bacteria. As considering the endosymbiont hypothesis, cyanobacteria were engulfed by the animal and plant cells. Later on, these bacteria performed the roles of mitochondria and chloroplastids in animals and plant cells respectively. Inner matrices of these organelles are having melatonin and probable function of this intra-organelle melatonin is to protect the organelles from the detrimental effects from free radicals (Reactive Oxygen Species; ROSs and Reactive Nitrogen Species; RNSs). In higher animals, melatonin is synthesized and secreted by the pineal gland mainly during the night, since light exposure suppresses its production. Other than pineal gland, melatonin is secreted from several different organs like retina, gastro-intestinal tract. The secretion of this hormone is regulated by several environmental factors like photo-period, temperature, humidity etc. Melatonin can exert its function either by as a free molecule or by its membrane bound receptors MT1 and MT2 respectively. Modulations of melatonin receptors results in stimulation of apoptosis, regulation of pro-survival signaling, inhibition on angiogenesis, metastasis, and induction of epigenetic alteration. Melatonin could also be utilized as adjuvant of cancer therapies, through reinforcing the therapeutic effects and reducing the side effects of chemotherapies or radiation. Melatonin could be an excellent candidate for prevention and treatment of several cancers, such as breast cancer, prostate cancer, gastric cancer and colorectal cancer. This review summarized the anticancer efficacy of melatonin, based on the results of epidemiological, experimental and clinical studies.

A Quasi Experimental Design was used for the present study & 50 women of reproductive age group were selected using purposive sampling technique. A structured questionnaire was used to assess the knowledge. The analysis and the data were based on the objective and hypothesis. Both descriptive and inferential statistics were used for data analysis. The Assessment of post- test knowledge score of the women of reproductive age group on prevention of cervical cancer shows that, Majority of women 34(68%) had good knowledge (13.59±1.189), 12(24%) had excellent knowledge (16.50±0.6742) and followed by 4(08%) having the average knowledge (10±00). It implies that, Majority of women having good, average and excellent knowledge in post test score after implementation of STP on knowledge of the women of reproductive age group on prevention of cervical cancer as compare to pre-test it shows that STP was effective educational strategies to create awareness.

A Quasi Experimental Design was used for the present study & 50 Mothers of under Five Children were selected using purposive sampling technique. A structured questionnaire was used to assess the knowledge & practices. Descriptive and inferential statistics were used to analyze the data. The analysis and the data were based on the objective and hypothesis. Both descriptive and inferential statistics were used for data analysis.The assessment of post- test knowledge score of the mother of under five children regarding prevention of pneumonia shows that, majority of mothers 29(58%) had good knowledge, 21(42%) having the average knowledge. And The assessment of post- test practice score of the mother of under five children regarding prevention of pneumonia shows that, majority of mothers 50(100%) had good practices. after implementation of STP on knowledge & practices of the mothers of under five children on prevention of pneumonia as compare to pre-test it shows that STP was effective educational strategies to create awareness.

Introduction: Incidence of dengue infection has increased around the world in recent decades and has become a major international public health concern. Early diagnosis is essential and clinical suspicion is based on the frequency of symptoms in the population. The exact clinical profile is important for management and prognosis. Objective: This study is an attempt to describe the Clinical Characteristics & Observation of Hospitalized Cases of Dengue Fever: A Study in Tertiary Care Hospital, Dhaka, Bangladesh. Materials and Methods: A hospital-based prospective study was undertaken in the Paediatrics Dept. in Tertiary Care Hospital, Dhaka, Bangladesh (July -October 2018). NS1 antigen and IgM dengue antibody-positive cases were included. These patients were admitted with fever, myalgia, headache, vomiting, abdominal pain or bleeding manifestations. NS1 antigen and IgM dengue antibody was estimated using capture ELISA. The diagnosis of dengue fever, dengue hemorrhagic fever and dengue shock syndrome was based on the WHO (World Health Organization) criteria. Results: The study enrolled 101 patients of suspected dengue fever of whom 51 (50.49%) were serologically confirmed to have dengue infection. 28 (55.0%) patients were males and 23 (45.0%) were females. 38 (37.62%) patients had classic dengue fever while 12 (11.88%) fulfilled the criteria of dengue hemorrhagic fever. Of those patients with dengue hemorrhagic fever, 6 patients had developed dengue shock syndrome. Conclusion: Dengue presents as a highly unspecific illness and is hardly recognized as a clinical entity by primary health care physicians. Dengue infection can have potentially fatal consequences, and to date, vector control methods to prevent the spread of the virus have been unsuccessful. Although there are promising vaccine candidates in development, further studies are required for a greater understanding of the humoral immune responses to Dengue infection and observation disease pathogenesis.

This research aims to examine The Effect of Perceived Ease of Use on the Quality of Accounting Information Systems and its Impact on the Quality of Accounting Information using the Technology Acceptance Model (TAM) approach. Population in this research are the staffs at the accounting department, procurement/purchasing department, project support units, and productions in one of the oils & gas companies in Jakarta. The samples are 60 respondents who operate the accounting systems and the Director and managerial level who use the accounting information. Data were collected using questionnaires that used the Likert scale. Distribution and collection of questionnaires were carried out in April 2020. The results of testing showed perceived ease of use affects the quality of information systems. However, the level of influence is also influenced by other factors outside the information system. Like standard operating procedures as internal company controls. Meanwhile, the accounting information quality is strongly influenced by the information system quality. The better the information system quality, the better the quality of the resulting accounting information system.

Background: Metabolic syndrome describes the co-occurrence of central adiposity, hyperglycemia, hypertension, lipid abnormalities and other metabolic changes that increase risk of cardiovascular, cerebrovascular, renal diseases. Non-alcoholic fatty liver disease (NAFLD) is associated with a substantial increased risk of cardiovascular disease (CVD), which is partly related to low HDL-C level. This multi-system condition has adverse effects on many organs, the liver being one of them. Non-alcoholic fatty liver disease appears to be the hepatic manifestation of metabolic syndrome, and is increasingly recognized as a major contributor to the burden of chronic liver disease world-wide. Objective: To find out the Association of Low HDL of NAFLD Patients With or Without Metabolic Syndrome. Materials and Methods: This is a cross sectional descriptive study which was conducted in the Department of Medicine, Rajshahi Medical College Hospital, Rajshahi, Bangladesh. 250 patients age above 20 years nonalcoholic both male and female were included for the study. All patients were interviewed by structured questionnaire. Statistical analysis was carried out by using the Statistical Package for the Social Sciences (SPSS) software version 23.0 for windows (SPSS Inc, Chicago, Illinois, USA). Results: Among 250 respondents a total of 67(26.8%) cases were diagnosed as metabolic syndrome and out of the 67 metabolic syndrome patients 23(34.33%) were male and 44(65.67%) were female. Out of the 23 male metabolic syndrome patients 9(39.13%) were diagnosed as NAFLD and out of the 44 female metabolic syndrome patients 16(36.36%) were diagnosed as NAFLD. Out of the 53 NAFLD patient’s 25 patients were presented with metabolic syndrome and 28 patients were without metabolic syndrome. Patients of NAFLD with metabolic syndrome presented with low HDL in 16(64%) cases. The difference was significant for high-density lipoprotein and waist circumference (p<0.05) between metabolic syndrome and non-metabolic syndrome patients. Conclusion: From the study, it can be concluded that the proportion of NAFLD significantly higher in metabolic syndrome patients compare to non-metabolic syndrome patients and metabolic syndrome is higher in female compare to male. The results of this study indicate that central obesity and dyslipidemia, with low HDL cholesterol, are important associates of NAFLD in patients.

Life of a parents with a child who agonizes from mental illness can be perplexing subsequently they need to have better understanding about the way their child’s mental illness presents itself in every life setting, this understanding may provide the foundation for seeking the treatment. Parental opinion and beliefs toward psychotropic drug compliance has a critical value that could improve or worse the course of treatment and the child’s mental health outcome. Aim: This study was conducted to assess the parental opinion and beliefs toward use of psychotropic drugs for treatment of mental health problems in children in the central region of the Kingdom of Saudi Arabia. Methods: A descriptive correlation cross section research design was utilized on a sample of 526 Saudi parents who were selected by a random location methodology. Data was collected using two part questionnaire, part one was the demographic data sheet, second part was a modified translated Arabic 16 item scale “parental opinion and beliefs toward use of psychotropic drugs for treatment of mental health problems in children.” Description about the purpose and nature of the study was explained to each individual potential participant. Participants were assured confidentiality of the collected data and that it will be used only by the researchers for the purpose of the current study. Data were analyzed using SPSS version 22. Results: Study revealed that half of the parents believed that some psychotropic drugs are dangerous for children. The total participants’ responses to the parental opinion and beliefs toward use of psychotropic drugs for treatment of mental health problems in children scale score ranged between 16 and 60 with higher scores indicating more accurate opinions and more favorable beliefs toward psychotropic medication prescription and administration to children. Correlation between selected demographic variables and parental opinion and beliefs toward use of psychotropic drugs for treatment of mental health problems in children, showed a highly statistically significant relationship between parents’ opinions and beliefs scores and the age of the parents, furthermore study findings revealed a highly statistically significant difference in the total opinion and beliefs score between participants with different marital status. Conclusion: Fear of psychiatric stigmatization and ignorance of the nature of mental disorders are important factors which influence the opinion and beliefs about psychotropic medication among parents of children with mental disorders,which threatens to rule out psychopharmacotherapy.The study findings showed the need for more education on scientific knowledge regarding the psychiatric treatment methods and its importance in managing psychiatric disorders among children.

Medicinal plants have attracted a great deal of scientific interest due to their potential as a source of natural biologically active compounds especially the antioxidant properties of medicinal plants that have created its wider applications including pharmaceuticals, alternate medicine, and natural therapies. The present study was to evaluate the qualitative estimation of phytochemicals and antioxidant properties from leaves, stem, and root of Neolamarckia cadamba and Cymbopogon citratus. In our study, we found the presence of steroids, flavonoids, alkaloids, tannins, saponins, and cardiac glycosides and antioxidant features in both plants and found suitable for the therapy of oxidative damages. In the present study, free radical scavenging percentage activity was found maximum in aqueous stem extract of Neolamarckia cadamba (81% with 1.5 ml extract) and least in aqueous stem and leaf extract of Cymbopogon citrates (1.67% and 1.67% with 0.5 ml respectively). From the present work, it becomes possible to conclude that these plants could be a promising source of bioactive compounds and warrant further study.

The idea suggested in this paper consists in forensic sketches that have to be drawn and furthermore analyzed from an emotional face recognition point of view. The detection itself is more effective and useful to further identify the future behavior and possible reactions of the suspect based on the emotional analysis of the areas on the face. The study embraces this idea and experiments with forensic like sketch images within a system that is trained on a FER+ database, and executed using two different schemes, ML (Multi-Label learning) and CEL (Cross-Entropy Loss). The conducting experiment resulted that for forensic sketch images, CEL system is more efficient than ML training method 69.77% vs 69.05% for the best test accuracy, even if the experiment on the standard image equivalents proved otherwise.

In this study, drying characteristics of two improved parboiled varieties of rice (FARO 44 and FARO 52) at air temperatures of 36oC, 45oC and 50oC were investigated. The drying data were fitted to seven thin layer drying models, namely, Agbashlo et al., Henderson and Pabis, Logarithmic, Newton, Two Term, Verma et al., and Wang and Singh. The models performances were evaluated by comparing the coefficient of determination (R2), standard error (SE) and relationship between the experimental and predicted moisture ratios through nonlinear regression analysis. The main factor controlling the drying rate was temperature and falling rate period characterized the entire drying process. The moisture content of the parboiled rice samples was found to be in the range of 26.33-27.57% (wb) which reduced to 8.87-9.98% (wb) for FARO 44 and 29.37-30.27% (wb) which reduced to 14.33-14.98% (wb) for FARO 52 after drying for various temperatures of 36°C, 45°C and 50°C for eight hours. The R2 and SE varied between 0.9953 - 0.9997, 0.9917- 0.9998, 0.9991 - 0.9999 and 0.9907 - 0.9994, 0.9986 – 1.0000 0.9300- 1.0000 for FARO 44 and FARO 52 respectively for the seven models. The three best models at 36°C for FARO 44 was the Logarithmic followed by Modified Henderson, Pabis and Newton. At 45°C, the Two term model was the best followed by Verma et al., Modified Henderson and Pabis. While for FARO 52 drying behaviour at each drying temperature of 36°C, the best model was the Two term followed by Wang and Singh and Logarithmic. The Two term model was the best model at 50°C. The Two term drying models satisfactorily described the drying behaviour which produced randomized residual plots with highest R2 and lowest standard error of estimates and gave best fitting curves.

This research aim is to examine and analyze pre-trial implementation of delegation and trial of main cases based on Law Number 8 of 1981 concerning Criminal Procedure Law in Indonesia currently and How to reconstruct the policy formulation of the pre-trial decision on the delegation and trial of the main case in an effort to maximize the pre-trial function in the criminal justice system in Indonesia in accordance with the value of justice? this research uses the method of empirical juridical approach where The data used in this study are primary data and secondary data, using qualitative analysis. The results showed that the Problems that arise in the pre-trial implementation of the delegation and trial of the main case based on Law Number 8 of 1981 cannot be applied because in Article 156 paragraph (1) the Court is not authorized to hear the case, or the indictment cannot be accepted, or the indictment must be annulled, or pre-trial has been granted regarding legal or Whether or not arrest, detention, termination of investigation or prosecution, compensation and or rehabilitation for a person whose criminal case is terminated at the level of investigation or prosecution, and whether or not the determination of a suspect is valid therefore, The reconstruction of the policy formulation of the decision of the Pre-Trial against the delegation and trial of the main case is by adding a sentence (phrase) so that in order to uphold justice and legal certainty the judge has a legal basis or reason for accepting objections or the exception of the accused or his legal adviser.