Background: Facial parameters such as facial, nasal, maxillary, mandibular and oro-facial change with age and are dependent on variations in the dimensions of the skeleton, development of muscles, sex and fat content and distribution in the body which are under the influence of climate, diet, health etc. these factors are important determinants of growth and development. Ethnicity is a variable that affects craniofacial dimensions. This study was done to determine whether there is a relationship between the facial height and nasal height of the Ikwerre people, establish a regression formula for predicting the facial height of the Ikwerre people using either nasal height or mandibular height and to examine if there are ethnic or racial differences when comparing the result in this study and previous studies. Materials and Methods: The study was cross-sectional that included males and females of the Ikwerre ethnicity of Rivers state of Nigeria. A total of 1,038 subjects comprising males (585) and females (453) aged between 5 – 45years were used for this study. The parents and grandparents were all from Ikwerre ethnic group. Each subject sat on a comfortable sitting position and then their facial measurements were taken including; facial height, nasal height, mandibular height, maxillary height and orofacial height. Results and Discussions: The facial height, nasal height, mandibular height, maxillary height and oro-facial height were measured using digital caliper and the results obtained showed that the males had mean facial height of 102.11± 9.07mm, nasal height of 37.07 ± 13.30mm, mandibular height of 45.10 ± 7.39mm, maxillary height of 20.85 ± 13.02mm, and oro-facial height of 65.91 ± 15.16mm while the females had mean facial height of 98.15 ± 6.96mm, nasal height of 36.65 ± 5.054mm, mandibular height of 41.43 ± 5.50mm, maxillary height of 19.43 ± 3.09mm, and oro-facial height of 60.86 ± 6.80mm. The result of the study showed that there is a progressive increase in the mean value of the facial height and nasal height with increase in age. This implies that there is an increase in the facial parameters with advancing age. This finding could be associated with natural growth and proportional body size increase i.e. facial growth. Conclusion: There is a relationship between the facial height and nasal height of the Ikwerre people which was seen as a positive correlation between the facial height and nasal height. It implies that for any increase in facial height, there is a resultant increase in nasal height amongst the Ikwerre people.

For better understanding and learning of the foreign language, it is necessary to learn its vocabulary first. With the passage of time new devices are being invented daily to meet the challenges to the modern world. Mobile phone is one of the best inventions of the twenty first century. The mobile phone not only use for communication purposes but for entertainment and teaching and learning process as well [1]. In the process of learning the mobile phone has contributed a lot, especially during covid-19. Mobile phones help students in their learning outside the classroom anywhere and anytime. The effect of using mobile phone for English vocabulary development of Pakistani secondary school students was investigated using mixed-method research design with 60 students studying in class 10th. The result of the study revealed that using mobile phone for vocabulary development is more effective than other traditional methodology.

The glycans are carbohydrate present with other macromolecules where it could act as ligand for glycan-binding protein called lectin. This glycan-lectin interaction plays important role in cell and organ functioning and immune regulation in both animals and humans. Glycan-lectin interaction is also utilized in viral pathogen interaction which is encoded through host genome or own genome replication and enhancement of infection. Current advancement in glycobiology investigations had revealed interaction between glycan and lectins mediating prominent interaction between host and virus which regulates spread of virus and activation of immune system. Carbohydrates are also found to be involved in viability and growth of cells. Glycosylation process occurs in the cells for regulated processing of secondary protein in the cells, it had an integral functioning in multiple processes ultimately to apoptosis. Glycan with glycan binding protein or solely could convey intracellular signals or extracellular signal control process which leads to initiation, execution of apoptosis program. Glycans and its binding proteins are important cell death machinery, glycan-lectin interactions could alter the spread of viral infections either profitable for virus or host. The interaction of glycan-lectin could be useful as can be used as a diagnostic or prognostic tool in tumor because it had ability of controlling cell apoptosis or cell functioning. This interaction also play prominent role in ocular infection associated pathogenesis and its immune response. The viral disease recently known had been spread in entire world cause due to coronavirus this interaction provide help in forming antiviral agents and gave various thoughts in field of vaccination for this virus. Therefore, all these findings reveled that glycan-lectin interactions are advantageous for various disease and also multiple process of our body.

Objective: To evaluate ovarian cysts detected in patients who had undergone previous hysterectomy and to study the clinical, pathological and surgical characteristics in these patients. Material and Methods: An observational study was conducted in the department of Obstetrics and Gynaecology, Mamata Medical College, Khammam over a period of 3 years on patients who had undergone previous hysterectomy. A detailed history, clinical presentation was taken from patients who had ovarian cysts was included in the study. The previous records, characteristics of ovarian cysts and management were evaluated in these patients. Results: A total of 700 post hysterectomy patients presented to OPD of them 66 patients identified with ovarian cysts were included in the study. Most of them (68%) underwent hysterectomy at the age of 40-50 years; abdominal hysterectomy was common mode of surgery (82%). AUB–L was the major indication for hysterectomy (44%), in 65% cases both the ovaries were preserved, pain abdomen was the commonest symptom patient had presented with (47%). The cysts were analysed with ultrasound and CA-125 levels and managed surgically in 44%, followed in 47% and 9% of them were referred to oncology. Histopathologically epithelial tumors were most common. Conclusion: All the post hysterectomy ovarian cysts should be managed individually based on symptoms, signs and size. Clinical evaluation and necessary investigations are to be done for better management either follow up or surgery. Not all post hysterectomy ovarian cysts need surgery.

Rohinton Mistry is widely acknowledged for his postcolonial approach to the marginalized. In his novels, he has not only highlighted the marginal position of the poor and the destitute in the Parsi community but also in the wider Indian society. In Family Matters, we find he locates the marginalized within the family set up also. The aged people are objects of neglect, more so in poor families where financing the upkeep of old people seems burdensome. As is his wont, Mistry shows the impact of dirty politics on ordinary, politically unattached lives. Politics is also responsible for the fall of the city of Bombay from a cosmopolitan to a ghettoized one. As an intellectual, Mistry cannot escape casting a glance at the declining numbers of the Parsi community and comes up with his views on the issue ty and how the community can forge links with other communities. For his focus on the Parsi identity, political suppression, and the weak and the destitute in society, Mistry comes out as a great postcolonial humanist.

Primary umbilical endometriosis is very rare.Painful umbilical nodule in a sub fertile woman can clinically be diagnosed as umbilical endometriosis. The treatment is surgical excision of umbilicus but subfertility is difficult to manage.

Giant Cell Granuloma is a rare bony lesion in the Head and Neck region. It mainly affects young adults between the age of 20 and 40. Occasionally, soft parts may be invaded, resulting from the direct effects of the parathyroid hormone. We report in this work the observation of a 36-year-old patient who presented for a maxillary tumor that revealed a parathyroid adenoma with associated hyperparathyroidism. The histopathological study of maxillary tumor’s material confirms the diagnostic of a giant cell granuloma.

The development of a biological profile involves the estimation of sex and stature of the deceased individual usually by the comparison of the antemortem and postmortem data. Due to inadequate studies on the development of a biological profile from the craniofacial region in the Nigerian population, this study aimed to determine sex and stature from craniofacial variables in the Yoruba ethnic group of southwest Nigeria. A prospective cross-sectional study was carried out on 368 students and staff (217 males and 151 females) of the Ekiti State University, Ado-Ekiti, Nigeria within the age range of 18 – 55 years. Twelve craniofacial variables and stature were taken using standard anthropometric procedures and equipment. Data were analyzed using IBM® SPSS version 25.0, Armonk, New York, USA. Student’s t-test Correlation analysis (Karl Pearson’s), multivariate regression and discriminant function analysis were carried out. The results revealed sex differences as the males have higher mean values compared to the females except for the bizygomatic breadth. Physiognomic facial height offers a significant model for stature estimation in both male and female subjects. However, the craniofacial variables produced weak correlations with stature and are not suitable for estimating stature in the ethnic group. Multivariate regression analysis provided better results. The discriminant function analysis sufficiently discriminated sex and after cross-validation, it produced an accuracy of 86.2% for males and 89.4% for females. Sex and stature can be reliably inferred from the craniofacial region but caution should be applied as it has proven to be sex and population specific.

Background: The FOXP3 gene provides instructions for producing the forkhead box P3 (FOXP3) protein. The FOXP3 protein attaches (binds) to specific regions of DNA and helps control the activity of genes that are involved in regulating the immune system. Aim: This study intended to analyze SNPs in FOXP3 gene in the coding region, 5`UTR and 3`UTR using bioinformatics tools and visualizing the 3D structure of the gene. Methods: SNPs were retrieved from NCBI, and the protein sequences were retrieved from UniprotKB. SIFT and Provean software was used to predict whether the nsSNPs were tolerated or deleterious. Polyphen- 2 for nsSNPs function prediction on the produced protein.I-mutant and Mupro software to check the protein stability, finally PHD software to see whether the nsSNPs were related to a disease or not.Regulomedb to predict the regulatory element for 5`UTR region. For the 3`UTR PolymiRTs database to predict the variation in microRNA (miRNA). FuncPred software to show the unknown function for the selected SNPs.TheI-TASSER to visualize the 3D structure. Results: A total of 205 SNPs were retrieved, 180 SNPs in the CDS region, 20 in 3`UTR, 5in 5`UTR. SIFT prediction resulted in 93 deleterious and 87 toleratednsSNPs, Proveanrevealed60 deleterious and 120 tolerated,Polyphen-2 resulted in 29 probably damaging,11 possiblydamaging, 3 benign and 2 no result. I-mutant showed 12nsSNPs increasing, and 25 decreasing the protein stability, MUpro resulted in 3nsSNPs increasing the protein stability and 42 decreasing the protein stability, PHD resulted in 17 nsSNPs as disease related and 28 as neutral. For noncoding SNPs, Regulomedb resulted in 11 SNPs, PolymiRTs result in 11, and FuncPred result. Conclusion: The analysis of FOXP3 gene showed that from 205 nsSNPs only 11 SNPs are highly damaging and 20 SNPs found in the 3UTR region which predicts its function using different methods. Still bioinformatics software have their limitations, the results from this study may be convenient in future for further population based research activities and towards development of perfect medicines.

Food insecurity caused by decline in food production due to shortage of workforce, has necessitated the automation of the various agricultural operations. The study was aimed at the design and development of a prototype drip irrigation robotic system, which used the internet services for its operation (Internet of Things). The robot has a microcontroller, soil moisture and temperature sensors and a water pump. During operation, the robot received the input commands through the soil temperature and moisture sensors. It had the ability to deter the water requirement of the targeted crop, before irrigating it autonomously with the right volume of water. Performance evaluation of the robotic system revealed that it had an efficiency of about 90% and accuracy of about 95% when controlled through the internet. This prototype will help in the production of automated drip irrigation robots, that will preformed effectively in the field.

Unilateral termination of a contract means the termination of the labor contract by the employer or the employee without the consent of the other party. Accordingly, when terminating the labor contract, there will be two cases, one is unilaterally terminating the labor contract in accordance with the law or unilaterally terminating the labor contract illegally. Although the law has a mechanism for one of the parties to unilaterally terminate the labor contract (hereinafter referred to as unilateral termination), to ensure benefits for the other party, the Labor Code also stipulates it is very clear which cases can be terminated, which cases cannot be terminated. Most of the cases that the law that allows unilateral termination may arise from other objective or subjective reasons, but in general, doing unilateral work will significantly reduce the significant damage to the party who is doing the job. This study focuses on analyzing the contents related to the termination of illegal labor contracts of both employers and employees, thereby pointing out the shortcomings in the Law, specifically the Ministry Labor Code 2019.

Autoimmunity simply stated is one's immune system responding to self. The occurrence of infectious disease is affected by interaction between microorganisms. The link between certain bacterial infections and autoimmunity is particularly compelling, and molecular mimicry is often implicated in autoimmune disease pathogenesis. The role of microorganisms in the spreading of diseases has undergone significant modification in the past few decades with new observations from clinical, epidemiologic, and basic science research. Primary bacterial colonizers are Staphylococcus epidermidis and other coagulase-negative Staphylococci. Other microorganisms that are generally regarded as skin colonizers are species of Corynebacterium, Propionibacterium and Brevibacterium. Adenovirus, herpesvirus, and poxvirus are all examples of large DNA viruses that infect humans. Adenoviruses, of which there are many types, cause gastroenteritis and respiratory disease in humans. Notable human diseases caused by RNA viruses include the common cold, influenza, SARS, MERS, COVID-19, Dengue Virus, hepatitis C, hepatitis E, West Nile fever, Ebola virus disease, rabies, polio, mumps, and measles. Parasitic diseases that can be blood borne include African trypanosomiasis, babesiosis, Chagas disease, leishmaniasis, malaria, and toxoplasmosis. Vaccinations are generally the cheapest and most effective trusted Source way to prevent viruses. Some vaccines have succeeded in eliminating diseases, such as smallpox.

Acute myocardial infarction is the leading cause of death. Streptokinase is the most commonly used thrombolytic agent. This study was conducted to compare in-hospital outcome of patients with acute myocardial infarction receiving streptokinase with those not receiving it. About 340 patients having acute MI were included in the study. Two groups were formed. Group 1 (SK Group) receiving streptokinase and Group 2(Non SK) not receiving streptokinase. For the patient condition assessment In-hospital mortality was the primary end while mechanical and electrical complications were the secondary end points. Among 340 patients, 255(75%) were males and 85(25%) females. Out of those 218 received streptokinase, while 122 did not receive the drug The mean age of group 1 was 53.1 ±10.3 years and group 2 age was 60.5 ± 16years. Mean time of arrival to the hospital after symptom onset was 10.4 ± 9.97 h. SK group patients reached in 5.9 ± 4.7 hours while group 2 in 19.4 ± 10.5 h. In-hospital mortality in group 1 and group 2 was 19(8.7%) and 25(20.5%) respectively, (p=0.002). Complication rate was significantly higher in non-streptokinase group. Patients of acute myocardial infarction receiving streptokinase have significantly lesser in hospital mortality and complications as compared to patients not receiving it.

Stealing, generally, has been recognised as a criminal offence and worldwide it has been viewed as the permanent deprivation of a person's ownership in a property by another. The concept of property has often been limited to material things which can be transferred to or inherited by another. This paper seeks to shed light on those other things that are not but should be considered property for the sake of defining the offence of stealing. In doing this, the effect of technology on the concept of stealing in Nigeria will be examined. A comparative analysis of the Nigerian status and the status of a few select jurisdictions, as regards the subject matter, will be done. It is believed that at the end of this paper, the concept of stealing will be viewed broader than it is seen now and that what the average person would normally see as fraud or "419" (using the Nigerian slang), will be clearly classified as stealing.

Since the outbreak of coronavirus disease 2019 (COVID-19) in late December 2019, it has brought significant harm and challenges to over 200 countries and geographic regions around the world. COVID-19 affects people in different ways, with patients exhibiting a range of symptoms and severity. Risk factors such as age, gender and comorbidities have been highlighted as increasing the risk of complications and mortality. These risk factors, however, do not account for the other 52% of deaths arising from COVID-19 in seemingly healthy individuals. This review examines the interplay between periodontal disease and development of severe complications of COVID 19. Periodontal infections alter the natural course of systemic conditions, due to the presence of a constant low grade systemic inflammatory state in the body. Correlating these two entities is the main focus of this review and how maintaining good oral health may reduce the risk of complications of COVID-19.