The analysis of Lead (Pb), Iron (Fe), Chromium(Cr) and PH in walnuts were carried out in four different locations which includes Rumueme, Eliozu/Air Force, Oil mill and Aba road, the lead, iron and Chromium concentrations were analysed using atomic absorption spectrophotometer. (AAS) while the PH of the samples were analysed using a ph meter . the results obtained showed wide variations of concentrations of heavy metals present in these different locations as shown in tables 4.1, 4.2,4.3 and 4.4, the level of lead in the four different locations were high compared to the World Health Organisation’s recommendation which is about 0.005mg, this was actually attributed to the industrial activities taking place in these areas, and this may result to some health risks like cancer, asthma, hypertention,etc if the walnuts sold in these areas are excessively consumed, however, the PH result obtained for the four different locations were 6.20,6.50.5..30 and 6.40 respectively, this revealed that the cooked walnuts are quite acidic and may be due to the sources of water and other environmental factors.

Protein is a major potential source of raw materials for new drugs. In this study, protein isolation of the red algae, Eucheuma cottonii was performed using a polar solvent (0.1 M Tris-HCl buffer). Purification of protein used fractionation method with ammonium sulfate, and then the last step of the isolation process performed protein dialysis. Determination of protein content was done using the Lowry method. Antibacterial activity test used agar diffusion method while for screening anticancer activity used the Brine Shrimp Lethality Test (BSLT) method. Anticancer effectiveness carried out against HeLa cancer cells. The results of antibacterial and BSLT tests on protein fractions F1 (0-20%) and F2 (20-40%) showed that these fractions were potential as anticancer agents, However, the test results of both fractions against HeLa cancer cells showed only the F2 protein fraction (20-40% fraction) was active in inhibiting the growth of HeLa cell cancer in the moderate category. The SDS PAGE electrophoresis test showed that the F2 protein fraction had a molecular weight of 26,76 kDa.

Ezrin, podocalyxin and paxillin are cytoskeleton-associated proteins, implicated in several malignancies, but their role in Urothelial carcinoma of the bladder (UCB) is still controversy. We investigated the expression of those markersin UCB and the association of their expression pattern with clinicopathological parameters.Quantitative rt-PCR analyses used to examine mRNA level of ezrin and paxillinin23 fresh specimens of UCB and adjacent normal mucosal tissues from patients undergoing cystoscopy.Also, immunohistochemical evaluation of ezrin, podocalyxin and paxillin was performed on 123 paraffin blocks of UCB. Ezrin mRNA levelwas significantly high in normal mucosa than in UCB (p=0.012) while paxillinmRNA level wasn'tsignificant (p=0.34). Significant negative correlation was found between membranous ezrin immunoexpression and prognostic parameters as grade,T-stage and recurrence(p=0.001, p<0.0001and p= 0.002 respectively). Regarding paxillin immunoexpression,significant negative correlation was detected with grade andT-stage (p<0.0001). Membranous expression of podocalyxin was significantly correlated with grade, T-stage and recurrence (p=0.016, p= 0.003 and p<0.0001respectively). A significant correlation was found between three markers.These results suggest that ezrin, podocalyxin and paxillin could be valuable prognostic molecules in evaluation of UCB and this might lead to establishment ofnew molecular therapeutic strategy and prognostic biomarkers in UCB.

Background: The effects of maxillary expansion depends on age and skeletal maturation of an individual. The review aims to identify the different parameters that can affect the amount of dental and skeletal effects achieved with expansion. Objective: Current literature regarding expansion techniques and the factors responsible for higher success rates were identified. The findings were evaluated and presented in a systematic manner. Results: There is a difference in the amount of skeletal effects of maxillary expansion in individuals with mineralized palatal suture. Conclusion: Bone-anchored maxillary expansion of mini implant supported palatal expansion (MARPE) can be useful in older individuals to achieve higher skeletal expansion and opening of mid palatal suture.

This research is normative juridical with descriptive analytical and qualitative approach, focusing on the main problem of how the role of Islamic boarding schools in the development of Islamic economics in the South Sulawesi region. Sharia economic discipline or fiqh muamalah is an original concept sourced from the Qur'an and Sunnah since the 7th century (Apostolate of Muhammad, 570-632 AD) contains Islamic teachings related to property, business or business, is the result of the ijtihad of the mujtahids related to laws or regulations. Humans in interacting with fellow humans, objects, and managing the contents of the universe based on the texts (Al-Quran and Assunnah). The results of the study indicate that the role of Islamic boarding schools in developing the Islamic economy has been substantively carried out for a long time and continuously in an integrated manner in the subject matter of fiqh muamalah at the Aliyah level, which is supported by learning documents such as textbooks and fiqh muamalah modules. The caregivers of muamalah fiqh subjects are not familiar with the term Sharia economics which is popular outside Islamic boarding schools, because the term is not found in the original fiqh books, which lasim is fiqh muamalah or muamalah iqtishadiyyah. In particular, the Islamic economic development policy at Islamic boarding schools has not been found in the vision and mission of Islamic boarding schools, but substantially it has been conducted for a long time through muamalah fiqh lessons, even coupled with mu'tabarah fiqh book halaqah activities outside formal learning hours.

Among the many contributions of Professor Rasidi Akinade Salawu to nursing profession in Nigeria, is his introduction into nursing of a model about the prevailing administrative and managerial environment in nursing. Although not formally documented all these years, many nurse managers, his colleagues as well as students (like us) who have encountered him have informally experienced and applied the tenets of this model in their day-to-day running of their wards and units. Drawing from Management and Nursing Science philosophies, Rasidi Akinade Salawu developed the Vice Syndrome Theory which has led to a better understanding of the intrigues and patterns in the working relationships between heads of units/departments/organisations and their deputies within the nursing circles. This presentation aims at sensitising the nursing (and general) scientific world to increase the awareness of this model, and increase its acceptance as an explanation for administrative processes and its application in a variety of research settings. This model has a great potential to make nursing administration more robust with sound scientific explanation. It will be an alternative paradigm for describing, explaining and predicting and therefore control issues of leader-deputy (“boss-vice”) engagements.

The problem in this study is to find weaknesses in Corporate Social Responsibility in Realizing Sustainable Development that is not valued with Justice and how to reconstruct it based on the values of justice. The approach method used in this study is qualitative research, with a sociological juridical approach, and analyzed using descriptive analysis. The conclusion of this study is the weakness of the construction of Article 74 of Law Number 40 of 2007 concerning Limited Liability Companies from the aspect of legal substance, legal structure, and legal culture has implications for the value of justice which cannot be realized in carrying out corporate social responsibility in realizing sustainable development in the form of CSR. Because of that Article, 74 of Law Number 40 of 2007 concerning Limited Liability Companies must be reconstructed so that Corporate Social Responsibility Values Justice which is appropriate and in line with the values of Pancasila justice.

Several procedures, methods, and techniques aiming at generating higher quality foodstuffs with minimal sensory and nutritive qualities have been developed and adapted over the past several decades. Pasteurization is a heat treatment procedure that kills harmful micro-organisms in foods and drinks. Pasteurized juices have been warmed to great temperatures for limited period of time to destroy any germs or bacteria which may still present. Double-pasteurization, that contains a subordinate heating procedure, can increase the shelf-life by killing the spores which have developed. Drying is indeed a natural method of prevent spoiling because most of the disease-causing microorganisms needed a humid environment to exist and grow. Chemical and physical methods of preserving food are used to destroy or hinder the development of germs. Modified atmosphere packaging, different conditions dehydration, controlled atmospheric storage, freezing, refrigeration, vacuum- packing, different forms of thermal treatment, ultraviolet-radiation, ionizing radiation, and extreme hydrostatic pressure are all physical ways of preserving food. canning heat methods are meant to eliminate the spores of a bacteria C. botulinum.

Introduction: Hypertension is one of the important causes of coronary heart disease and cerebrovascular disease. The autonomic nervous system has a significant role in the circulatory system and blood pressure regulation. Analysis of heart rate variability (HRV) is a non-invasive tool that is widely used to assess autonomic nervous function. Aims & Objectives: The study aimed to analyze HRV in Hypertensive individuals. Materials & Methods: An analytical study was conducted on 50 normotensives and 50 hypertensives in the age group of 40–60 years. Blood pressure was measured by using a sphygmomanometer in sitting position. According to JNC VII criteria, normotensives are those with SBP ≤ 120 mmHg and DBP ≤ 80 mmHg. Hypertensives are those with SBP ≥ 140 mmHg and DBP ≥ 90 mmHg. HRV is measured for 2min using Polar H10 chest strap and data is analyzed using Elite HRV software. In Time-domain methods Mean RR, SDNN, RMSSD, and PNN50 were assessed. In Frequency domain methods LF, HF, and LF/HF were assessed. The data was entered into Excel 2016 and SPSS version 21 was used for analysis. An unpaired “t” test was used to compare the HRV values between normotensive and hypertensive groups. Results: Mean HR, SDNN, RMSSD, PNN50, and HF were found to be decreased and LF, LF/HF were increased in hypertensives suggesting increased sympathetic activity and reduced parasympathetic activity in hypertensives. All the values were statistically significant (p<0.01). Conclusion: There is increased sympathetic activity and a decreased vagal tone associated with hypertension. Thus HRV can be used as a routine screening test to predict the future risk of hypertension at an earlier stage and also for a better prognosis during treatment.

Corruption is an act that can not only harm the state's finances but can also cause losses to the people's economy. Corruption is a very despicable act, condemned and very hated by most people, not only by the Indonesian people and nation but also by the people of the nations of the world. The problem in this study is to find weaknesses in the application of the criminal sanction system in eradicating corruption and how to reconstruct it based on justice value. This research is using the constructivism paradigm and sociological-Juridical approach. The results of the study are that the weaknesses in the aspect of legal substance are the Law on the Eradication of Criminal Acts of Corruption does not regulate the number of minimum sanctions based on the classification of the amount of money that is corrupted, both for cases of embezzlement, bribery or gratification, and sanctions are also considered less firm. Weaknesses from the aspect of the legal structure are the weak coordination between law enforcement officers that causes the handling of corruption crimes to be hampered by time and bureaucracy. Weaknesses from the aspect of legal culture are the emergence of corruption itself is strongly influenced by the demands of individual and group needs and is supported by a socio-cultural environment that inherits a corrupt tradition. Accordingly, it is necessary to reconstruct Law Number 31 of 1999 concerning the Eradication of Corruption Crimes by adding paragraphs in the article up to Article 3 and Article 5.

The composition and therapeutic values of the essential oils obtained from the leaves of O. gratissimum and L. martinicensis was investigated. The GC-MS results reveals the presence of bioactive compound such as eucalyptol (10.99%), estragole (48.52%) and linalool (24.49%) in O. gratissimum while for the Leucas martinicensis its reveals the presence of diazoprogesterone (0.15%), Isoaromadendrene epoxide (0.10%) and beta.-copaene (4.37%). Oxalic acid, oleic acid, p-Menth-8(10)-en-9-ol, and Caryophyllene was detected in the essential oils of both plants. The IR-spectroscopy results confirmed the functional group of most of the compound identified. Test for tannins, flavonoids, steroids, cardiac glycoside, alkaloids terpenoid, and anthraquinone were positive in methanolic and aqueous extracts of both plants. The in vitro antimicrobial screening of the essential oils against S. aureous, E.coli, S. pneumonia, K. pneumonia, A. niger and C. albicans showed that they are potential antimicrobial agents. The DPPH scavenging activity of essential oils showed that L. martinicensis with an IC50 of (145.7ug/ml) have higher antioxidant activity than essential oil obtained from the leaves of O. gratissimum with the IC50 of (158.3ug/ml) but their activities is lower than the standard with IC50 of (134.3ug/ml) and (145.7ug/ml) respectively.

Climate change affects the plant growth by inhibiting the genes involved for promoting the roots, shoots, leaves and reproduction. Toxic gases that accumulated in the air due to heavy chimneys can cause serious environmental and health hazards. Wastewater released from industries can increase the risk of environmental pollution that can be treated through highly effective treatments plants. Soil conservation helps to mitigate these threats of climate change and traditional farming practices by replacing the traditional farming methods employed for agriculture land. Soil conversation through green manure practices required less labor and lower costs that increase farmers profits. Microbial biomass also increases the soil fertility relative to conventional agricultural systems by marinating the nutritional balance between crops and microorganisms. CRISPR is the latest technology for controlling the different microorganisms that causes soil salinity and abnormal growth of seed developments. Nitrogenous fertilizers contribute substantially to the greenhouse gas emissions that promote climate change.

Introduction: Hand hygiene is most important measure to minimize the ratio of transmission of health care associated infections (HCAIs) as this is one of the major problem especially in developing countries and most of the time caused behind it is poor hand hygiene of health care providers especially nurses as they have maximum interaction to the patients .This study was conducted to assess the knowledge and practices regarding hand hygiene among the nurses of DHQ hospital Okara. Methodology: A self-structured questionnaire with the help of WHO guidelines base cross sectional study was done on the sample of 100 nurses among the nurses of DHQ hospital Okara. Likert scale was used to assess their knowledge and they knowledge were scored as good (13-15), average (9-12) and poor (0-8) according to their responses. Practices were also assessed by questionnaire. Results: Most of the participants showed having good (51%) and average (39%) knowledge and there are only some nurses (4%) who showed poor results. But despite of having sufficient knowledge there was no implementation of hand hygiene because of lacking of facilities, over burden of patients, shortage of time. Conclusion: To improve the practices of hand hygiene continues training sessions, sufficient nurses, and provision of all facilities needed for the hand hygiene are most important things.

Development of high temperature dense refractory bricks using clay minerals and grog has been carried out with a view to determining the consequence of variation in percentages of Al2O3.2SiO2.2H2O and grog on the properties of locally produced dense bricks. The raw materials were used to compose five batches (of five samples each) from all the clay minerals and their blends (ED1–EN5). The clay bodies were hydraulically shaped and oven dried at 1100C. The properties of the produced bricks investigated after sintering at 13500C indicated that samples ED1–EN5 had shrinkage ranging from 8.4%-11.5% with corresponding bulk density of 1.57g/cm3–2.26g/cm3 respectively. The investigation revealed that samples ED1–EN5 of the bricks as stated above had compressive strength ranging from 13.5MPa–23.1MPa with corresponding porosity ranging from 12.84% -23.39% respectively. The estimated refractoriness using shuen’s formula shows that samples ED–EN5 had 16660c-17680c, while the result of the refractoriness using pyrometric cone equivalent indicated that samples ED1–EN5 had cone 30(16600C)– <34(<17500C) respectively. The spalling-count test result revealed that samples as stated above had number of cycles ranging from 19-35 respectively. It was discovered that the higher the grog content, the lower the shrinkage, bulk density and compressive strength while the higher the porosity, spalling-count-cycle with refractoriness, and vice versa when considering blended samples with increase in Al2O3.2SiO2.2H2O content. However, sample EN4 gave the most apposite result when considering the properties stated above. Therefore sample EN4 is recommended for mass production of dense refractory bricks for high temperature applications.

The purpose of the study was to investigate “Effects Of Roasted Garlic With And Without Moringa On Mean Atrial Pressure, Thyroid Stimulating Hormone And Testosterone Among Sedentary Men”. Selection Of Variables: The following variables were selected for this study. I. Dependent Varibles: Mean Atrial Pressure, Thyroid Stimulating Hormone And Testosterone. II. Independent Variables: 1. Roasted Garlic With Moringa Oleifera 2. Roasted Garlic 3.Control Group. Experimental Design: forty five The subject were selected for this study through the random group design consisting of pre and post test, forty five men randomly divided into three groups, the group was assigned as an Experimental Group I Experimental Group II and control group. The groups are 1. Roasted Garlic with Moringa Oleifera 2. Roasted Garlic 3.Control Group. Training Schedules: During the training period, the experimental group underwent their training program period of eight weeks for all days. The experimental groups underwent training for forty five minutes of duration in evening hours between 4:30 to 5:30 p.m for seven days per week. Statistical Technique: Analysis of Covariance statistical technique was used, to test the significant difference among the treatment groups. If the adjusted post-test results were significant, the scheffe’s post hoc test was used to determine the paired mean significant difference. Thirumalaisamy R. (2004). Result: After Incorporate Statistical Technique, It Was Found That A Significant Decrease Mean Atrial Pressure And Thyroid Stimulating Hormone And Testosterone In Experimental Group I (Roasted Garlic With Moringa Oleifera), when compared with experimental II and This Change Due To Eight Weeks Of training Among sedentary Men.