Effect of solvent, temperature, pH and time on extraction process of anti-thiamine factor present in Bergenia ciliate leaves was studied. Results showed that extraction of the leaf-extract with ethanol at 40º C for 15 minutes at pH 3.0 had maximum anti-thiamine activity in in vitro experiments.

This study purposed to determine the impact of the microenvironment on firm value with the macro environment as the moderator variable. This research population is the pharmaceutical sub-sector companies listed on the Indonesia Stock Exchange in terms 2015-2020. Samples that suit the criteria are eight companies. The data were analyzed using panel data regression with a multiplication interaction structure so that there were 48 observations. The results showed that the Fixed Effect is the best model. The study results simultaneously show that the microenvironment is measured using investment decision variables, market penetration, and inventory turnover. The macro-environment, as measured using the GDP variable, has a significant and positive effect on firm value. Partly, investment decisions and inventory turnover have a positive and significant effect on firm value, while market penetration has no impact on firm value. Meanwhile, GDP can only moderate investment decisions and inventory turnover and not moderate market penetration.

This study's purpose is to analyze the impact of world oil prices, world gold prices, inflation, and USD/IDR exchange rates on the Composite Stock Price Index (IHSG) on the Indonesia Stock Exchange (IDX). Secondary data was obtained from the London Financial Market Association (LBMA), Bank Indonesia, and investing.com. The variables used in this study are world oil prices, world gold prices, USD/IDR exchange rates, and inflation as independent variables—also, the Composite Stock Price Index (CSPI) as the dependent variable. This study was conducted using secondary data per month in 2015-2019, non-participant observation with a saturated sampling method of 60 months. The analysis used in this research is Least Square and Autoregressive Moving Average (LS&ARMA) regression analysis. Simultaneous research results show that world oil prices, gold prices, USD/IDR exchange rates, and inflation significantly affect the Composite Stock Price Index (JCI). The study results partially show that world gold prices and inflation have an important adverse effect on the JCI, while world oil prices significantly positively impact the JCI. It is different from the USD/IDR exchange rate, which does not influence the JCI. The practical conclusion of this research is to afford information to investors that world gold prices, world oil prices, and inflation should be considered in making investment decisions in the capital market.

Thyroid malignant nodules (TMNs) are the most common endocrine cancer and the fifth most frequently occurring type of malignancies. The etiology and pathogenesis of TMNs must be considered as multifactorial. The present study was performed to clarify the role of some chemical elements (ChEs) in the etiology of these thyroid disorders. Thyroid tissue levels of nineteen ChEs were prospectively evaluated in malignant tumor and tissue adjacent to tumor of 41 patients with TMNs. Measurements were performed using a combination of non-destructive and destructive methods: instrumental neutron activation analysis with high resolution spectrometry of short-lived radionuclides and inductively coupled plasma atomic emission spectrometry. Results of the study were additionally compared with previously obtained data for the same ChEs in “normal” thyroid tissue. It was observed that in malignant tissue the mass fractions of Al, B, Ca, Cl, Cu, K, Mg, Mn, Na, P, S, and Si were 3.14, 4.64, 1.79, 2.26, 3.55, 1.57, 1.61, 1.57, 1.24, 2.45, 1.14, and 2.81 times, respectively, higher whereas mass fraction of I was 25.6 times lower than in the normal thyroid. In the “adjacent” group mean mass fractions of Cl and I were approximately 1.6 and 1.7 times, respectively, higher, while mean values of Ba, Ca and Sr content were 55%, 45%, and 70%, respectively, lower than in the “normal” group. In tumor Ca, Cl, Cu, K, and Sr contents were approximately 2.8, 1.4, 1.8, 1.7, and 5.4 times, respectively, higher, while I content was 43 times lower than in “adjacent” group of tissue samples. It was concluded that thyroid tissue adjacent to malignant nodules kept the main function of thyroid gland, while malignantly transformed thyroid cells lost its capacity to accumulate I. It was supposed that the excessive accumulation of Cl and I by thyroid tissue probably precede the TMNs origination and development. It was also supposed that elevated levels of Al, B, Ca, Cl, Cu, K, Mg, Mn, Na, P, S, and Si, as well as drastically reduced level of me in cancerous tissue could possibly be explored for differential diagnosis of benign and malignant thyroid nodules.

Student learning must be developmentally appropriate and compatible with students' levels of intellectual, physical, social, and emotional development. Variety of instructional materials can be used during the teaching- learning process to make learning enjoyable and student centered. The in-hand longitudinal study was conducted on a sample of 60 school going students, between 10 and 14 years of age, of Yadavindra Public School (YPS), Patiala, Punjab, India from 2016 to 2017, in order to analyze and record the effect of the regular intervention of customized education and guidance on the cognitive development and academic achievement of students. It was notified that if the students are taught according to their respective learning nature, they will grasp much easily and develop their interest in studies. Through the in-depth study, it was inferred that the interest in studies developed among those receiving education through the methods linking directly to their strength and dominant learning style.

This paper examines the relationship between knowledge core competence strategy and performance of Deposit Money Banks in Rivers State, Nigeria. The research design adopted was survey research design through cross sectional design that examined how knowledge core competence strategy enhanced the performance of Deposit Money Banks in Rivers State, Nigeria. The population consisted of seventeen (17) regional Deposit Money Banks in Rivers State, Nigeria. The sample size of one hundred and seventy (170) was determined from the seventeen Regional Deposit Money Banks in Rivers State, Nigeria. This comprises of one (1) top manager, five (5) middle managers, and ten (10) lower managers. One hundred and seventy questionnaire were distributed, while hundred and thirty were retrieved and used for the analysis dues to some irregularities in answering the questions. The collected data was analyzed using the Spearman’s Rank Order Correlation Coefficient with the aid of Statistical Package for Social Science (SPSS) within a significance level of 0.05. The findings showed that there is a strong positive relationship between knowledge core competence strategy and performance of Deposit Money Banks in Rivers State, Nigeria. We therefore recommended that Deposit Money Banks in Rivers should implement adequate measures of knowledge core competences which includes; organizational area of interest, skill performance, technology, human capacity or know how that will enhance customers satisfaction and increase patronage of Deposit Money Banks in Rivers State, Nigeria.

Recently we have shown that Bergenia ciliate (B. ciliate, Family- Saxifragacae) leaves of the period July – August had maximum in vitro anti thiamine effect. Aim of the present work was, to isolate anti thiamine compound from the leaves of B. ciliate. From the local market B. ciliate leaves were collected during July – August and identified by the taxonomist. Solvent extraction and acid hydrolysis were done followed by solvent treatment, chromatographic experiments and crystallization. A compound was crystallized. In vitro anti thiamine activity of the isolated compound was checked by standard method. Results revealed that 100 mg of the isolated compound could inactivate 29.5 mg of thiamine hydrochloride in in vitro experiment.

Polyherbal formula has been used everywhere in the global because of its medicinal and healing application. It has additionally referred to as polyherbal therapy or herb-herb combination. In an age of integrated healthcare where Ayush therapies are being accepted along side the fashionable medicine, we see that these are separate compartments in theory and practice. Wound healing begins at the time of injury and can last for a variety of times depending on the severity of the wound. The wound healing process can be divided into three stages: the inflammatory phase, the proliferative phase, and finally the remodelling phase, which determines the strength and appearance of the healed tissues. In the present work an attempt had been made to evaluate wound healing potential of Polyherbal formulation contains Punica granatum and Coleus aromaticus extract in burn wound model.

Plants are rich in phytochemical compounds that offer a source of dietary ingredients used to treat various ailments and problems. Among medicinal plants, mint (Mentha species) exhibits multiple health beneficial properties, such as prevention from cancer development and anti-obesity, antimicrobial, anti-inflammatory, anti-diabetic, and cardioprotective effects, as a result of its antioxidant potential, combined with low toxicity and high efficacy. Essential oils from mint have also been found to exert antibacterial activities. Using fresh mint and other herbs and spices in cooking can help a person add flavor while reducing their sodium and sugar intake.

Effect of season on in vitro anti-thiamine activity of Bergenia ciliate (B. ciliate, Family- Saxifragacae) leaves was studied. Results showed that leaves of B. ciliate of the period July – August had maximum in vitro anti thiamine effect.

An estimated 1 million people die each year from HBV infection. This investigation aimed to determine the frequency, distribution, and risk factors for HBV infection in a healthy Bangladeshi community. A cross-sectional study among the general population was conducted in Dhaka Medical College Hospital. A series of 100 patients with the chronic liver disease between 18 to 49 years. Diagnosed based on clinical and biochemical parameters were collected. All medicine units of Dhaka Medical College Hospital have been analyzed regarding the seroprevalence of HBsAg and its correlation with the demographic pattern. Among 100 cases of liver disease, the number of CLD patients was 85, of which 56 (65.88%) were HBsAg positive 29 (34.11%) were HBsAg negative. The number of patients with acute viral hepatitis was 15, of which 4(26.66%) were HBsAg positive, 11(73.33%) were HBsAg negative, and the overall seroprevalence was 60%. The age incidence was more below 40 years (83%) less above the age of 40(17%). Males had higher seropositivity (70.31%) than females (41.66%). People of all ages are susceptible, particularly the farmers (21.66%) and manual laborers (13.33%). Most of the patients belong to the poor (62.79%) and middle class (62.22%). Urban people were more (60.93%) susceptible than rural people (58.33%). Married persons were more (70.27%) prone than unmarried (30.76%). Seroprevalence of HBsAg was more in those people who had a history of blood and blood product transfusion (84.61%). Illiterate persons were more (75%) susceptible than literate (59.37%). Seroprevalence of HBsAg was more in those who had a history of instrumental tooth extraction (68.42%) than those who had not (58.02%). People who cut their beards and mustache in the barbershop were more susceptible (73.91%) than those who got it by themselves (68.29%). Among female persons, those who underwent instrumental delivery were more susceptible than those who delivered their baby by normal vaginal delivery.

Cryptococcosis is a frequent and severe opportunistic mycosis caused by encapsulated yeast of the genus Cryptococcus. It is common in immunocompromised patients, particularly those infected with the human immunodeficiency virus. We report in our work a case of cryptococcemia in a patient with covid-19 under anti-inflammatory treatment. The diagnosis was based on the presence of encapsulated yeasts with Indian ink and positive culture on Sabouraud medium without cycloheximide with identification of Cryptococcus neoformans as the causative agent. The patient's outcome was fatal.

Background: A significant proportion of people infected with COVID-19 report new onset of smell and taste loss. The duration of the chemosensory impairment and prognostic factors of recovery is still unclear. We aimed to investigate the prevalence rate and other signs and symptoms which are predictors in patients. Objective: To find out the association of Anosmia and Ageusia with COVID-19. To find out relationship of Gender with Anosmia and Ageusia in COVID-19 or other URTI. Methods: I was a cross-sectional study, participants were from CMH, Multan, Hospitals of different cities of the province of Punjab, Pakistan. The study was conducted from 1st July to 31st of August 2021. 185. All faculty members and medical Students of CMH Bahawalpur. Results: Out of 185 participants, 99 (53.5%) were male and 86 (46.5%) were female. The mean age was 23.93 ± 6.661years. Pearson correlation of covid-19 with loss of smell is 0.533 which shows that there is strong positive relationship between them. On one-way ANOVA fever sig. is 0.002 which shows high significance. URTI also shows association but other signs and symptoms like dyspnoea, dry cough do not show any significance. Shows the majority of participants are suffering from taste and smell loss (95.1%) along with body aches (82.7%), dyspnoea (94.6%), acute dry cough (36.2%), URTI (19.5%) and fever (36.2%).

This study is interested in the question of learning scientific knowledge related mainly to environmental education in an informal education setting through a sample composed of visually impaired students (14 students), belonging to a Club of environmental education at the ATEEA headquarters, in the region of Sfax. Six stories and six knowledge / understanding tests on various environmental themes were administered during six sessions. Each session was spread over 3 moments, namely a pretest evaluating initial knowledge; recitation of the story (by the storytelling technique in the experimental group (N = 7) and by the reading technique in the control group (N = 7) and finally a post-test involving the same concepts mentioned in the preliminary test. Analysis of the mean scores between pre-tests and post-tests shows a significant improvement in correct answers for students in both groups. On the other hand, the students of the storytelling group showed a significantly higher performance than that of the students of the reading group at the level of the correct answers to the causal propositions. Thus, the storytelling methods made it possible to compensate for the loss of learning leading to the understanding of the different narrative texts recited in the experimental group. The study recommended using stories and the practice of storytelling in school and out-of-school context (clubs, sequences recorded on educational platforms, etc.) in order to remedy the learning loss for visually impaired students in a particular way and for other students in general.

Objective: To evaluate the relationship between canine guided and group function occlusion schemes and tooth wear along with salivary factors such as salivary flow rate and salivary pH. Methodology: A cross sectional descriptive study was conducted among 50 subjects, 25 of group function and 25 of canine guided occlusion. Type of occlusion pattern and tooth wear was assessed through clinical intra-oral examination. Lateral excursive occlusion was determined with the aid of Shimstock to confirm tooth contact and the modified ordinal scale was used for evaluating tooth wear. Working side occlusal contact patterns were determined and classified into two groups: canine guided and group function. Unstimulated and stimulated whole saliva sample was collected to assess the pH and salivary flow rate. Data was analyzed using Statistical Package for Social Sciences (SPSS) version 21, IBM Inc. Descriptive data was reported for each variable. As the data was found to be normally distributed bivariate analyses was performed using Independent t test. Level of statistical significance was set at p-value less than 0.05 Results: No significant difference was seen in pH when compared between canine guided and Group function occlusion as p >0.05 whereas flow rate was found to be significantly more in group function. Conclusion: Most of tooth wear in canine guidance is reported in mandibular incisor followed by mandibular molar. No wear was seen in both maxillary and mandibular canines and minimal wear was reported in maxillary incisor. Type of occlusion did not affect the salivary pH rather it affected salivary flow rate.