Background: Diabetes is a group of metabolic disorders, characterized by hyperglycemia which results from defects in insulin secretion, insulin action, or both. The prevalence and incidence of type 2 diabetes are rising rapidly worldwide. Diabetes has been linked to a shorter life expectancy mainly because of its complications, including heart disease, strokes, retinopathy, and chronic kidney disease and bone disease. Objective: To examine the relationship between high sensitive C reactive protein (hsCRP) and alkaline phosphatase (ALP) in type 2 diabetic patients. Methods: This study was a hospital based cross sectional study conducted at Dept. of Biochemistry, Ashiyan Medical College Hospital from January to June 2020. The study consists of 180 patients out of which 90 were normal healthy controls (Group I) and 90 patients having type 2 DM were included in case (Group II). FBS, PPBS, HbA1c, hsCRP and ALP of all subjects were measured. Results: Mean serum hsCRP and ALP level were statistically significant higher in case group compared to control group. Moreover, significant positive correlation was observed between hsCRP and ALP level as well as both with FBS, PPBS and HbA1c. Conclusions: Oxidative stress and inflammation appears to be a key component and also associated with poor glycaemic control and further pathogenesis of diabetes and its complications. All our finding suggest a link between oxidative stress, inflammation and glycaemic control in patient with type 2 diabetes mellitus.

The middle income trap is a spectre looming up in front of countries who have performed well to rise up to middle income level from the lower income level, and are hoping for a quick admission to upper income echelons. Unfortunately, the trap seems unavoidable for many middle income nations, as seen poignantly in the case of Argentina and even Brazil. This paper tries to pinpoint the performance parameters that distinguish countries such as Malaysia and Chile who have been successful in avoiding getting mired in the trap – and may be now even viewing it nonchalantly as just a mirage appearing during the development process. The parameters identified as probable positive forces include the pillars of the Global Competitive Index, in addition to the usual suspects appearing in economic growth theory and estimations. Estimation of coefficients was carried by cross-country regressions using a sample of seventy upper and lower income nations. ICT adaptation, innovative capabilities, health standards, and openness as represented by FDI and export ratios to GDP were identified as parameters identified as important in closing the per capita income gap towards high income nations.

Human T cell Lymphotrophic Virus (HTLV-I/II) is an oncogenic retrovirus known to cause adult T cell leukemia which is transmitted vertically from mother to child and sexually by infected lymphocytes. Studies suggest that the onset of adult T-cell leukemia/lymphoma (ATL) in patients infected with HTLV-I/II occurs significantly earlier when the subjects are coinfected with S. stercoralis. This study was aimed at detecting antibodies to HTLV-I/II and Strongyloides stercoralis larvae among pregnant women on antenatal visits to selected hospitals in Jos, Nigeria. A total of 188 blood samples and 136 stool samples were collected for study. Five milliliters (5ml) of venous blood was collected and transferred into a screw capped plastic tube without anticoagulant and sera extracted from each participant’s sample and later analyzed for antibodies to HTLV-I/II using double-antigen sandwich enzyme linked immunosorbent assay (ELISA) kit. Stool samples were also analyzed using direct stool microscopy and Baemanns technique. Questionnaires were administered for participants’ demographics and assessment of risk factors. Data obtained were then analyzed using SPSS version 17. Human T cell Lymphotrophic Virus –I/II prevalence of 2.13% (4/188) was detected following the ELISA procedures with 1.06% (2/188) indeterminate results. Risk factors assessed had no statistical association with HTLV-I/II infection except for history of cancer in a family. Five parasite species were detected on stool examination with 2.2% prevalence of Strongyloides stercoralis. Keeping of pet dogs and having itching around legs were statistically associated with Strongyloidiasis (P< 0.05). Routine monitoring of HTLV-I/II and dewormming of pregnant women on antenatal should be a matter of priority.

Diabetes mellitus (DM) is a serious metabolic disorder characterized by elevated blood glucose. The raised blood glucose level if not properly managed can results in damage and failure of several vital organs such as the eyes, kidneys, nerves, heart, and blood vessels. The aim of this study was to evaluate the effects of co-administration of melatonin and magnesium on blood glucose level of streptozotocin-induced Type 1 diabetic Wistar rats. To achieve this aim sixty-four Wistar rats were used in the study. Streptozotocin (STZ) was used to induce chemical type 1 diabetes mellitus (T1DM) after two weeks acclimatization period in fifty-eight Wistar rats. Fifty-three rats were diabetic and fourty-eight diabetic rats were randomly distributed in eight groups and six normal normoglycaemic rats were used as control. The animals were assigned into nine groups as follows, Normal control group (NC), Diabetic control (DC) group, Melatonin Low dose group of 10 mg/kgb (MLD), magnesium low dose group of 240 mg/kgbw (MgLD), melatonin and magnesium combined low dose group of 10mg/kgbw+240mg/kgbw (MMgLD), melatonin high dose group of 20mg/kgbw (MHD), magnesium high dose group of 480mg/kgbw (MgHD), melatonin and magnesium high dose combined group of 20mg/kgbw+480mg/kgbw (MMgHD) and insulin at 500mg/kgbw group (IN). Melatonin and insulin were administered through intraperitoneal injections (IP) while magnesium was by oral administration. The control groups were given placebo and all group treatment was for twenty-one days. Blood glucose was measured weekly in all groups by day 8, day 15 and day 22. At the end of the evaluation Day 22, the blood glucose levels showed a highly significant decrease (p˂0.05) in melatonin treatment group at low dose (MLD), melatonin and magnesium combined group at low doses (MMgLD), melatonin treatment group at high doses (MHD) and insulin treated group (IN) when compared with normoglycaemic group (NC) while groups treated with Magnesium at low doses (MgLD), magnesium treated group at high doses and melatonin and magnesium treatment group at high doses (MMgHD) showed no significant decrease (p˂0.05) in blood glucose levels as compared with diabetic control (DC). Melatonin and magnesium co-administration has hypoglycaemic effects on blood glucose levels in STZ-induced type 1 diabetic Wistar rats.

Heavy metal ions present in the groundwater are toxic pollutants which contaminated of water is a world-wide environmental problem. This paper studies that an attempt made to adsorption kinetics of Indigo carmine dye from dye effluents onto activated carbon modified with metal chlorides is keen interest. The results show that activated carbon modified with metal chlorides such as FeCl2, SrCl2, and BaCl2 can be used as effective adsorbents for the removal Indigo carmine dye from dye effluents was observed. The kinetics of indigo carmine dye was adsorbed onto activated carbon modified metal chlorides were analyzed using pseudo-first order and pseudo-second order. Results were found to follow pseudo-second order equation.

The purpose of this study was to investigate the difference of kinematic variables between two. Back handspring and Forward Handspring performance of 05 male gymnasts of L.N.I.P.E, Gwalior was recorded. They aged between 19 to 25 years. Purposive sampling technique was used for choosing highly skilled gymnast. These gymnasts had 7 to 12 years training experience and were technically sound on the stated skills. Videography technique was employed in order to register the performance of the subjects in Back Handspring and Forward Handspring. The Canon – 70D camera was used with the frequency of 24 frames per second and the subjects were video graphed in horizontal plane (sagittal plane) from the left side. Each subject was given three trails and the best trail was used for analysis. The selected phases were taken out from the video by using snipping tool software. From the photographic sequence, the stick figures of the selected movements and there angles were located by kinovea software. The data was analyzed by using Independent T-Test. There were two skills that were Back handspring and Forward handspring which was further divided into two phases, Initial Phase and Ground Touch Phase and Shoulder joint, Elbow Joint and wrist joint were selected as the angular kinematics variables. The level of significance was set at 0.05. The results revealed that all selected angular kinematic variables at all the phase had shown insignificant deference with the Back Handspring and Forward Handspring. On the basis of results it is concluded that that the performance of any games and sports depending upon the multidimensional factors such as physical factors, physiological factors, psychological factors and so many other factors.

Introduction: Cerebral palsy is a disorder due to non-progressive brain damage on an immature brain, occurring before, during or after birth. Oral repercussions are often present but overlooked. Hence, the description oral health and oral motor skills of children affected by this condition. Methods: A descriptive cross-sectional study was conducted for eight months, in two specialized centers in the city of Yaoundé. Information was collected from medical records, consents obtained and oral examination of patients performed. The significance threshold was considered for p < 0.05. Results: Of the 60 patients included, 56.7% suffered from spastic hemiplegia, 50% had a level III gross motor classification system (GMFCS) and 28.3% had a level II. Their oral condition and oral-motor dexterity revealed salivary and labial incontinence, poor oral hygiene in 28.3% of cases, severe gingival inflammation in 34 patients (56.7%),the loss of part of the food ingested in 50 patients (84%) and swallowing and phonation disorders, respectively in 88.3% of cases and swallowing. A significant association between the severity of BMI and the occurrence of caries (P=0.001) and gingivitis (P=0.01). Conclusion: Oral health and oral motility of IMC patients is a function of the severity of brain damage. This oral state, requiring a specialized odontostomatology follow-up adapted to the handicap presented by the patient.

Background: Solid pseudopapillary tumor of the pancreas (SPPT) or Frantz's tumor is a rare exocrine pancreatic tumor, it generally occurs among females within the second or third decade of life. The clinical symptomatology is non-specific, frequently presenting as a slowly growing abdominal mass without any biological abnormalities. The imaging usually shows a well-limited mass with little vascularity. Endoscopic ultrasound (EUS) with fine needle aspiration (FNA) helps the diagnosis. The treatment of these tumors is surgical, and the prognosis is excellent after complete resection. We report two new cases of Frantz tumor, detailing the clinicopathological features of this rare neoplasm. Case presentation: Case 1: A 19-year-old woman presented with middle upper abdominal pain. Computed tomography (CT) scan showed a solitary encapsulated mass in the pancreatic body. Endoscopic ultrasound showed a regular, well-defined, heterogenous lesion, measuring 50 × 46 cm, in the pancreatic body. endoscopic ultrasound fine-needle aspiration was then performed with cytopathological analysis compatible with SPPT. Body computed tomography confirmed the absence of metastases and she underwent a central pancreatectomy. 12 months after the diagnosis, she remains asymptomatic, continuing regular follow-up. Case 2: A 22-year-old woman presented with epigastric pain and weight loss. CT scan revealed a single 5 cm well defined mass in the pancreatic head. EUS showed a well-defined heterogenous hypoechoic encapsulated mass in the pancreatic head, measuring 64 × 44 mm; EUS-FNA was performed and cytopathological analysis was suggestive of SPPT. She underwent conventional cephalic duodenopancreatectomy. She presented septic postoperative complications, with a favorable outcome after medical and surgical therapy. she remains asymptomatic, after 6 months follow-up. Conclusion: Solid pseudo papillary pancreatic tumor is a rare exocrine low-grade neoplasm. EUS is a sensitive tool in the diagnosis of SPPT, identifying and characterizing the pathologic lesions, and allowing EUS-FNA with cytomorphological recognition, making it an invaluable tool for establishing diagnosis, helping clinical management and surgical planning.

Several studies has reported the use of neural networks in the dynamic modelling and simulation of heavy duty turbines. However; focus on exhaust gas temperature a key indicator of turbine thermal health is yet to be made. In this paper the modelling of exhaust gas temperature using the non-linear autoregressive network and subsequent multi step prediction with data collected from GT13E2 turbine was embarked upon. Features which were statistically significant for EGT prediction were selected through stepwise regression. One hidden layer was sufficient to approximate the function and The optimal architecture for training was achieved by training the network with a fixed hidden neuron and varying time delay at the inputs and output. It is observed that the optimal performance is realized when the prediction is regressed at tapped input delay of 1 in open loop. 7 hidden neuron and 1 tapped delay is selected for function approximation after series of neurons ranging from 4-15 was tested. The appropriate model was carefully selected by utilizing the method of holdout cross validation, corrected Akaike Informationon Criterion and Schwartz Bayesian information criterion. The final architecture was trained, and converted to close loop NARX network where 100 time steps ahead prediction of EGT was made. Although it was observed that accuracy diminishes as prediction horizon increases, the chosen optimised architecture successfully predicted EGT 100 steps ahead with MAE of 2.9665 and RMSE of 3.9675. Therefore; the dynamic NARX model can be utilized for multistep ahead prediction in incidence of sensor malfunction at the turbine outlet of heavy duty gas turbines.

This research aims to find out what economic sectors have the potential to be prioritized for development in Tasikmalaya City. This research uses descriptive and quantitative analysis. While the quantitative analysis used the Location Quotient (LQ) Model, Growth Ratio Model (MRP), and Overlay Analysis. should be a development priority by the local government of Tasikmalaya City, which is expected to increase the rate of regional economic growth in Tasikmalaya City.

Primary intraosseous squamous cell carcinoma of jaw is a rare tumour. It arises from the lining of an odontogenic cyst or de novo from postulated odontogenic cell rests and is rarely diagnosed by FNAC. The primary intraosseous carcinoma of squamous cell origin is very infrequent and only few cases are reported in available literature. The following case report describes a case of primary intraosseous squamous cell carcinoma of mandible in a 45 year old male patient with emphasis on cytological features. The main purpose is to highlight diagnostic significance of FNAC for rapid and accurate diagnosis of lesions of mandible and unusual clinical presentation.

employee performance with work motivation as a mediating variable for PT Panggung Jaya Indah employees. Quantitative research method with an associative approach was used as research method. All of permanent employees of PT Panggung Jaya Indah were used as a population. Based on the structural equation modeling or SEM model, this research sample was using 235 permanent employees with a sampling technique using purposive sampling. The research data was collected through the dissemination of questionnaires. The analytical techniques using Partial Least Square or PLS. The results showed that job insecurity has negative and significant effect on work motivation and employee performance. Otherwise, Covid-19 health protocols and compensation have positive and significant impact on work motivation and employee performance.

This paper analyzes the three elements of the structure of legal English (conditional sentence, logical connector and and or, modified limit components), and proposes how these three elements can be used in Chinese and English legal translation to avoid ambiguity or error in a long sentence.

The aim of this study is to determine and analyze the influence of transformational leadership on the dimensions of inspirational motivation, idealized influence, intellectual stimulation, individual consideration at Muhammadiyah Higher Education (PTM) in the Cirebon area and examine the mediating role of relational marketing practices between transformational leadership on the dimensions of inspirational motivation, idealized influence, intellectual stimulation, individual consideration of the Image of Muhammadiyah Higher Education (PTM) in the Cirebon area. Respondents of this study were employees at two PTMs in the Cirebon Region, namely the University of Muhammadiyah Cirebon and the Cirebon Muhammadiyah College of Health (STIKES) with a total of 120. This research is a mixed methods research, which combines two forms of approaches in research, namely qualitative and qualitative. Mixed method research is a research approach that combines qualitative research with quantitative research. Mix methods are research methods by combining two research methods at once, qualitative and quantitative in a research activity, so that more comprehensive, valid, reliable, and objective data will be obtained. The data analysis technique used is Structural Equation Modeling (SEM). The results show: transformational leadership through inspirational motivation with an index reaching 88.4, idealized influence with an index reaching 89, intellectual stimulation with an index reaching 85.3, and individual consideration with an index reaching 83.5, it is concluded that transformational leadership through these indicators can improve the practice of relational marketing and can build the image of PTM throughout the Cirebon Region. Furthermore, the practice of relational marketing mediates the effect of transformational leadership through inspirational motivation, idealized influence, intellectual stimulation, and individual consideration on the image of PTM.

Since the late 2019, the COVID 19 has had a series of illnesses in patients who had an attack of infection. These symptoms exist in patients even long after the recovery phase. These are called the long COVID syndromes. The current article examines the contribution of Homoeopathy to deal with these long COVID issues. The article traces the syndrome in its major forms & its implications on other aspects of the body. Thereafter, it deals with the subject of the changing face of the pattern of symptoms through the dimension of how, why, when, where and whom of these patterns. Following that the burden of the long COVID is explained through the social & economic impacts that it has exerted while perpetuating poverty. Taking cue from one of the elaborate & established books in the Homoeopathic world, it deals with what Homoeopathy had offered, is offering & the potential to offer in the future to deal with this long COVID pandemic.