Student learning must be developmentally appropriate and compatible with students' levels of intellectual, physical, social, and emotional development. Variety of instructional materials can be used during the teaching- learning process to make learning enjoyable and student centered. The in-hand longitudinal study was conducted on a sample of 60 school going students, between 10 and 14 years of age, of Yadavindra Public School (YPS), Patiala, Punjab, India from 2016 to 2017, in order to analyze and record the effect of the regular intervention of customized education and guidance on the cognitive development and academic achievement of students. It was notified that if the students are taught according to their respective learning nature, they will grasp much easily and develop their interest in studies. Through the in-depth study, it was inferred that the interest in studies developed among those receiving education through the methods linking directly to their strength and dominant learning style.

This paper examines the relationship between knowledge core competence strategy and performance of Deposit Money Banks in Rivers State, Nigeria. The research design adopted was survey research design through cross sectional design that examined how knowledge core competence strategy enhanced the performance of Deposit Money Banks in Rivers State, Nigeria. The population consisted of seventeen (17) regional Deposit Money Banks in Rivers State, Nigeria. The sample size of one hundred and seventy (170) was determined from the seventeen Regional Deposit Money Banks in Rivers State, Nigeria. This comprises of one (1) top manager, five (5) middle managers, and ten (10) lower managers. One hundred and seventy questionnaire were distributed, while hundred and thirty were retrieved and used for the analysis dues to some irregularities in answering the questions. The collected data was analyzed using the Spearman’s Rank Order Correlation Coefficient with the aid of Statistical Package for Social Science (SPSS) within a significance level of 0.05. The findings showed that there is a strong positive relationship between knowledge core competence strategy and performance of Deposit Money Banks in Rivers State, Nigeria. We therefore recommended that Deposit Money Banks in Rivers should implement adequate measures of knowledge core competences which includes; organizational area of interest, skill performance, technology, human capacity or know how that will enhance customers satisfaction and increase patronage of Deposit Money Banks in Rivers State, Nigeria.

Recently we have shown that Bergenia ciliate (B. ciliate, Family- Saxifragacae) leaves of the period July – August had maximum in vitro anti thiamine effect. Aim of the present work was, to isolate anti thiamine compound from the leaves of B. ciliate. From the local market B. ciliate leaves were collected during July – August and identified by the taxonomist. Solvent extraction and acid hydrolysis were done followed by solvent treatment, chromatographic experiments and crystallization. A compound was crystallized. In vitro anti thiamine activity of the isolated compound was checked by standard method. Results revealed that 100 mg of the isolated compound could inactivate 29.5 mg of thiamine hydrochloride in in vitro experiment.

Polyherbal formula has been used everywhere in the global because of its medicinal and healing application. It has additionally referred to as polyherbal therapy or herb-herb combination. In an age of integrated healthcare where Ayush therapies are being accepted along side the fashionable medicine, we see that these are separate compartments in theory and practice. Wound healing begins at the time of injury and can last for a variety of times depending on the severity of the wound. The wound healing process can be divided into three stages: the inflammatory phase, the proliferative phase, and finally the remodelling phase, which determines the strength and appearance of the healed tissues. In the present work an attempt had been made to evaluate wound healing potential of Polyherbal formulation contains Punica granatum and Coleus aromaticus extract in burn wound model.

Plants are rich in phytochemical compounds that offer a source of dietary ingredients used to treat various ailments and problems. Among medicinal plants, mint (Mentha species) exhibits multiple health beneficial properties, such as prevention from cancer development and anti-obesity, antimicrobial, anti-inflammatory, anti-diabetic, and cardioprotective effects, as a result of its antioxidant potential, combined with low toxicity and high efficacy. Essential oils from mint have also been found to exert antibacterial activities. Using fresh mint and other herbs and spices in cooking can help a person add flavor while reducing their sodium and sugar intake.

Effect of season on in vitro anti-thiamine activity of Bergenia ciliate (B. ciliate, Family- Saxifragacae) leaves was studied. Results showed that leaves of B. ciliate of the period July – August had maximum in vitro anti thiamine effect.

An estimated 1 million people die each year from HBV infection. This investigation aimed to determine the frequency, distribution, and risk factors for HBV infection in a healthy Bangladeshi community. A cross-sectional study among the general population was conducted in Dhaka Medical College Hospital. A series of 100 patients with the chronic liver disease between 18 to 49 years. Diagnosed based on clinical and biochemical parameters were collected. All medicine units of Dhaka Medical College Hospital have been analyzed regarding the seroprevalence of HBsAg and its correlation with the demographic pattern. Among 100 cases of liver disease, the number of CLD patients was 85, of which 56 (65.88%) were HBsAg positive 29 (34.11%) were HBsAg negative. The number of patients with acute viral hepatitis was 15, of which 4(26.66%) were HBsAg positive, 11(73.33%) were HBsAg negative, and the overall seroprevalence was 60%. The age incidence was more below 40 years (83%) less above the age of 40(17%). Males had higher seropositivity (70.31%) than females (41.66%). People of all ages are susceptible, particularly the farmers (21.66%) and manual laborers (13.33%). Most of the patients belong to the poor (62.79%) and middle class (62.22%). Urban people were more (60.93%) susceptible than rural people (58.33%). Married persons were more (70.27%) prone than unmarried (30.76%). Seroprevalence of HBsAg was more in those people who had a history of blood and blood product transfusion (84.61%). Illiterate persons were more (75%) susceptible than literate (59.37%). Seroprevalence of HBsAg was more in those who had a history of instrumental tooth extraction (68.42%) than those who had not (58.02%). People who cut their beards and mustache in the barbershop were more susceptible (73.91%) than those who got it by themselves (68.29%). Among female persons, those who underwent instrumental delivery were more susceptible than those who delivered their baby by normal vaginal delivery.

Cryptococcosis is a frequent and severe opportunistic mycosis caused by encapsulated yeast of the genus Cryptococcus. It is common in immunocompromised patients, particularly those infected with the human immunodeficiency virus. We report in our work a case of cryptococcemia in a patient with covid-19 under anti-inflammatory treatment. The diagnosis was based on the presence of encapsulated yeasts with Indian ink and positive culture on Sabouraud medium without cycloheximide with identification of Cryptococcus neoformans as the causative agent. The patient's outcome was fatal.

Background: A significant proportion of people infected with COVID-19 report new onset of smell and taste loss. The duration of the chemosensory impairment and prognostic factors of recovery is still unclear. We aimed to investigate the prevalence rate and other signs and symptoms which are predictors in patients. Objective: To find out the association of Anosmia and Ageusia with COVID-19. To find out relationship of Gender with Anosmia and Ageusia in COVID-19 or other URTI. Methods: I was a cross-sectional study, participants were from CMH, Multan, Hospitals of different cities of the province of Punjab, Pakistan. The study was conducted from 1st July to 31st of August 2021. 185. All faculty members and medical Students of CMH Bahawalpur. Results: Out of 185 participants, 99 (53.5%) were male and 86 (46.5%) were female. The mean age was 23.93 ± 6.661years. Pearson correlation of covid-19 with loss of smell is 0.533 which shows that there is strong positive relationship between them. On one-way ANOVA fever sig. is 0.002 which shows high significance. URTI also shows association but other signs and symptoms like dyspnoea, dry cough do not show any significance. Shows the majority of participants are suffering from taste and smell loss (95.1%) along with body aches (82.7%), dyspnoea (94.6%), acute dry cough (36.2%), URTI (19.5%) and fever (36.2%).

This study is interested in the question of learning scientific knowledge related mainly to environmental education in an informal education setting through a sample composed of visually impaired students (14 students), belonging to a Club of environmental education at the ATEEA headquarters, in the region of Sfax. Six stories and six knowledge / understanding tests on various environmental themes were administered during six sessions. Each session was spread over 3 moments, namely a pretest evaluating initial knowledge; recitation of the story (by the storytelling technique in the experimental group (N = 7) and by the reading technique in the control group (N = 7) and finally a post-test involving the same concepts mentioned in the preliminary test. Analysis of the mean scores between pre-tests and post-tests shows a significant improvement in correct answers for students in both groups. On the other hand, the students of the storytelling group showed a significantly higher performance than that of the students of the reading group at the level of the correct answers to the causal propositions. Thus, the storytelling methods made it possible to compensate for the loss of learning leading to the understanding of the different narrative texts recited in the experimental group. The study recommended using stories and the practice of storytelling in school and out-of-school context (clubs, sequences recorded on educational platforms, etc.) in order to remedy the learning loss for visually impaired students in a particular way and for other students in general.

Objective: To evaluate the relationship between canine guided and group function occlusion schemes and tooth wear along with salivary factors such as salivary flow rate and salivary pH. Methodology: A cross sectional descriptive study was conducted among 50 subjects, 25 of group function and 25 of canine guided occlusion. Type of occlusion pattern and tooth wear was assessed through clinical intra-oral examination. Lateral excursive occlusion was determined with the aid of Shimstock to confirm tooth contact and the modified ordinal scale was used for evaluating tooth wear. Working side occlusal contact patterns were determined and classified into two groups: canine guided and group function. Unstimulated and stimulated whole saliva sample was collected to assess the pH and salivary flow rate. Data was analyzed using Statistical Package for Social Sciences (SPSS) version 21, IBM Inc. Descriptive data was reported for each variable. As the data was found to be normally distributed bivariate analyses was performed using Independent t test. Level of statistical significance was set at p-value less than 0.05 Results: No significant difference was seen in pH when compared between canine guided and Group function occlusion as p >0.05 whereas flow rate was found to be significantly more in group function. Conclusion: Most of tooth wear in canine guidance is reported in mandibular incisor followed by mandibular molar. No wear was seen in both maxillary and mandibular canines and minimal wear was reported in maxillary incisor. Type of occlusion did not affect the salivary pH rather it affected salivary flow rate.

This paper aims at uncovering and fragmenting the foundations of Locke’s theory of knowledge as addressed in An Essay Concerning Human Understanding. Systematically, it reveals the origin of knowledge, develops and evaluates the limits of human knowledge and the extent of understanding, as well as critically examines what is knowable with more emphasis on certain and probabilistic grounds. Certainty is attainable through two principal means, comprising the use of the human senses and adoption of abstract reasoning. The sources of human knowledge are significant in easing and enhancing our knowledge of God as it facilitates the justification of his existence, portraying orderliness in the world, and positing mankind as part of God’s creatures expected to implement moral lifestyles through the appeal to reasoning as a law of nature even when in a state of nature. The value of this principle is evident for self-preservation, including an essential moral obligation for the preservation of everybody. The ethical basis of the state of nature featuring both moral and natural laws, signals the natural moral nature of man as determined by a rational order designed by a rational and knowable God.

The study was carried out to assess the effect of oral administration of Moringa oleifera seed extract following aspartame consumption on the intestinal wall. Twenty-seven (27) rats were used for this study. They were divided into nine groups. Group A, the control group were administered distilled water, Group B were administered 0.4 ml of Aspartame, Group C were administered 1.5 ml of Aspartame, Group D1 were administered 0.6 ml of aspartame for the first three weeks followed by 1.5 ml of ethanolic extract of ground moringa seed on the fourth week, Group D2 was administered 0.5 ml of aspartame for the first three week followed by 1.3 ml of n-Hexane extract of ground moringa seed on the fourth week, Group E1 were administered 1.3 ml of apartame for the first three weeks, followed by 2.5 ml of ethanolic extract of ground moringa seed on the fourth week, Group E2, were administered 1.5 ml of aspartame for the first three weeks followed by 3.0 ml of n-Hexane extract of ground moringa seed on the fourth week, Group F1 were administered 1.4 ml of aspartame and 2.8 ml of ethanolic extract of ground moringa seed from week one to week four. Group F2 were administered 1.3 ml of aspartame and 2.5 ml of n-Hexane extract of ground moringa seed from week one to week four. The experiment lasted for 28 days. The rats were weighed once a week. On the 28th day, the rats were anaesthetized via chloroform inhalation; the large intestine harvested and fixed in 10% buffered formalin, processed and stained with Harris Haematoxylin and Eosin (H&E). Blood were harvested for analysis of Blood Glucose Level. Data were expressed as Mean ± standard error of the Mean (M±SEM) and subjected to one-way analysis of variance. Significant difference between mean was accessed by Student-New-Man-Keuls post hoc test. 95% level of significance (p < 0.05) was used for statistical analysis. Ethanolic extract of Moringa oleifera seed extract could not protect the Large intestine from the toxic effect of aspartame while the n-Hexane extract of Moringa oleifera seed has a protective effect on the large intestine.

The purpose of this research is to provide light on the trauma experienced by females in Pakistan, particularly in upper Sindh. This research shall show how women are murdered in the name of honor as a result of this investigation. Nafisa Shah, the author of this book, has worked as a journalist, researcher, and administrator. She is from upper Sindh, which explains why she went into depth about the genuine unpleasant truths of Karo kari (A detestable ritual). The author recounts the instances of women who were assassinated in the sake of honor. Additionally, she highlights the experiences of women who strive for their life, escape, and successfully survive. Karo kari is a colloquial term for honor killing. Karo kari, or honor killing, is a long-standing ritual in rural Pakistan, particularly in upper Sindh. Nafisa Shah is a writer who stumbled into politics. In Pakistan, honor killing is referred to as karo kari. This deed is performed in order to restore the family's honor. This is a widespread practice in Pakistan, particularly in upper Sindh. Activists on both the international and Pakistani levels are working to end this practice. A qualitative approach has been used to analyses the text of Nafisa shah in order to get the desired answers.

Black pepper, the King of spices (Piper nigrum L.), is a widely used spice, known for its pungent odour. From time immemorial, plant sources were used in traditional systems of medicine and day-to-day common use, such as in meal preparation and cosmetic purposes. This is due to their vast pharmacological potential with beneficial effects. Among the various species of the Piperaceae family, black pepper is one of the most popular due to its principle pharmacological component, piperine. Which is an alkaloid that has diverse pharmacological activities like antioxidant, antiobesity, antitumor, antipyretic, anticonvulsant, antithyroid, antifungal, antibacterial, insecticidal, hepatoprotective, antiasthmatic, larvicidal, antihypertensive, antiinflammatory, antidiabetic, antidiarrheal, bioavailability enhancer, immunomodulatory, antiepileptic, antifertility, GI stimulant, lipid metabolism accelerator, anticancer, CNS stimulant, diuretic, aphrodisiac, blood purifier and antiplatelet activities, etc. Due to the some religious values of black pepper, its being popular from ancient times which is beneficial to modern generation. This review is aimed to provide a literature review on recent advancement of chemistry, pharmacognosy, pharmacological activities, new Piperine based formulations and other general use of Piper nigrum.