Background: Coronavirus disease 2019 (COVID-19) is characterized by a variable clinical picture ranging from asymptomatic to severe or even critical forms that can be life-threatening. The biological assessment can also be within the limits of normality, even little disturbed or outright witness of an excessive inflammatory response or a real cytokine storm which would follow the virological phase of the disease. The objective of our study is to evaluate the contribution of inflammatory biomarkers: LDH, procalcitonin (PCT), ferritin, C-reactive protein (CRP) and the level of lymphocytes, in the prediction of mortality in COVID-19 patients. Methods: We collected 79 patients diagnosed with COVID-19 on the basis of a set of clinical, radiological and / or biological arguments, which we divided into two groups: Survivors (N = 45) and deceased (N = 34). All these patients had all the biomarkers measured upon admission. Results: In our study, we found that the levels of the four inflammatory biomarkers studied in our series were elevated in both groups of patients (survivors and decedents), however, the decedents did not have significantly higher levels than the survivors (P >0.05).

Perforation of the gallbladder during laparoscopic cholecystectomy is common and results in the spillage of stones into the abdominal cavity. Most of these buried gallbladder stones are clinically silent, but a small percentage can develop complications such as infections, abscesses, and fistulas months or years after surgery If these stones are ignored and not removed from the abdominal cavity. This review presents a 59-year-old woman who was complicated by chronic supra-umbilical discharge from the camera site port, after six months of surgery. The patient had a previous history of multiple abscess drainage, and the radiological examination revealed abdominal gallstones in the abdominal cavity and attached to the abdominal wall with no connection to the abdominal organs. This study discusses our case and reviews the literature on the prevention and treatment of spilled gallstones after laparoscopic cholecystectomy.

Song Ci, as a kind of literary expression, serves as an important part of Chinese literature. Ci writers use the technique of metaphor to express their feelings, but scholars have relatively little research on the English translation of Song Ci metaphors. Guided by the conceptual metaphor theory, this paper makes a comparative analysis of the translations of Xu Yuanchong and Clara Candlin from three aspects: structural metaphor, ontological metaphor and orientational metaphor to explore appropriate translation methods of reducing the loss of metaphor, and to make the target readers appreciate similar metaphor images as the original readers.

Periodontitis is a risk factor for children who practice poor oral hygiene at home. This is due to the higher frequency of association between children’s and parents’ microbiota. It is likely due to the influence of both, hereditary and environmental factors. Although it is possible for periodontal disease to be passed down across generations, the underlying mechanism behind this is still unknown. According to clinical study, genetic predisposition accounts for 50% of an individual’s sensitivity to periodontal disease. Because clear information on the issue is sparse, the purpose of this study is to examine the known studies on the impact of a family history of periodontal disease on children. English-language articles, case reports, and case series published from 2013 to 2022, taken from the Cochrane Library, SCOPUS, and MEDLINE databases (through PubMed) in accordance with PRISMA criteria were reviewed to research children with a history of periodontal disease. researchers for relevant materials. Twenty-nine children from various case studies were included in the present systematic study. In nine of the 29 studies, no family members had Hereditary gingival fibromatosis, a kind of periodontal disease while a family member had in the other 20 studies. One person had Zimmemrman-Laband Syndrome, two had severe periodontal disease, one had juvenile hyaline fibromatosis, and the other two had non-syndromic Hereditary gingival fibromatosis in four independent tests. In three case studies, children whose parents have periodontitis are likely to have periodontal disease. Children who have periodontal disease are more likely to develop the illness and should be checked and treated very once. More research is needed, especially well-designed studies that avoid the flaws mentioned in the publications included in this review.

Background: The current era is a digital era. Every individual spending a lot of time using digital screens for almost everything from work and school to socializing and fun. COVID-19 pandemic further increased the screen time as people stayed indoors and forced to spend more time on screen media. Several studies conducted and revealed the effects of excessive screen time on health and wellbeing. Since youth are the change makers of the society, the current study aimed to conduct on the youths. Results: The findings of the study revealed that, youth in Saudi Arabia spending 7 hrs. daily on an average on screen media. Gender wise females are spending (8 hrs. average) more time on screen media than males (7 hrs. average). Watching movies and other entertaining programs and social media use have highly significant association with increased screen time. More than 50% participants agreed with the fact that their amount of screen media use behaviour affecting their life in diverse way such as, they neglect daily activities, losing sleep, grades suffer and it bothers to their family too. Physical wellbeing markers such as BMI (0.03), suffering from asthma (0.006), suffering from headache often (0.03), suffering from food indigestion often (0.03); psychological wellbeing markers like, feel depressed/low mood/sad often (0.004) and feel lonely often (0.05) have significant association with daily amount of screen time. Social wellbeing markers such as like to spend time with family (< 0.001), like to talk or visit with friends or relatives (< 0.001), like parties (< 0.001) and academic performance marker like grade achieved in recent exam attended (< 0.001) have highly significant association with daily amount of screen time among the Saudi youths. Conclusions: The current study is an eye opener for the whole world to sensitize them for limiting their screen time in order to live a healthy, happy and more active lifestyle.

The study examined the impact of fiscal policy on unemployment in Nigeria. The main objective of the study is to find out the relationship between fiscal policy like recurrent expenditure, capital expenditure, debt servicing and some variables like inflation rate, interest rate spread, gross fixed capital formation on unemployment. The study used expo-factor research design with Auto Regressive Distributed Lag (ARDL) in analyzing the data collected from CBN statistical bulletin. The result revealed that government capital expenditure, gross fixed capital formation and debt servicing impacted significantly on unemployment, while inflation rate, interest rate and recurrent government expenditure had insignificant impact on unemployment. Based on the findings, the study concludes that fiscal policy has a significant impact on unemployment. It was recommended that government expenditure should be channeled towards productive sectors which are capable of absorbing the teeming unemployed in the society and not luxuries and stop further acquiring more loans.

This study aimed at evaluating the toxicity of the methanolic extract of Cylicodiscus gabunensis stem bark, a plant traditionally used against female fertility problems. Acute toxicity was evaluated in rats by sequential administration of a single dose of 2000 mg/kg and 5000 mg/kg of body weight of extract according to the method described by protocol 425 of the Organization for Cooperation and economic development. Subacute toxicity was assessed by daily administration of the extract at 100, 200 and 400 mg/kg for 28 days. The weight evolution and the signs of toxicity were observed, the biochemical and haematological parameters of the blood of the animals were collected and analysed. The administration of the extract at 2000 and 5000 mg/kg caused no death and no toxic signs. The weight evolution, the biochemical and haematological parameters of the surviving rats were analysed and compared with those of the controls. Acute oral toxicity data determined that the LD50 of the extract is greater than 5000 mg/kg. Repeated dose administration did not cause any deaths or significant changes in haematological parameters. Some signs of intoxication were however noted and certain biochemical parameters analysed in the rats showed statistically significant differences compared to the controls. A decrease in creatinine was observed on the renal level, an increase in transaminases and a decrease in alkaline phosphatase on the hepatic level. An increase in total proteins at 100 and 200 mg/kg and triglycerides at 100 mg/kg were observed and also a significant drop in LDL-cholesterol at 100, 200 and 400 mg/kg. This study shows that the stem barks of C. gabunensis would be moderately toxic in repeated oral administration, additional studies should be carried out to determine the effect of the extract on the tissues of the different organs.

The most popular way to invest is through mutual funds in today's world. Profitability is particularly high in the Saudi financial market for mutual fund companies. Investors prefer Islamic mutual funds over non-Islamic mutual funds because they believe they are more secure and risk-free. This research aims to vary the customer preferences toward Islamic mutual funds, which offer higher returns within the Saudi economic market. All these will be identified as victimization sure key facts. With the assistance of those critical facts, a capitalist will analyze dissimilar mutual funds and put his cash in an exceeding fund that fits his exposure perception. This study evaluated the Mutual fund returns using, Maximum returns, Minimum returns, and Average returns compounded by the annual growth rate. The standard deviation and risk per average return (standard deviation/average return) have been used to evaluate the risk and return of the funds. Furthermore, fund managers assess the fund’s performance in terms of –Performance for the existing year (YTD) of the fund. As a result of the research, it was discovered that the overall performance of mutual investments in Saudi Arabia's economic market was better than expected for all the selected funds.

This study was aimed to analyze how human capital, work engagement, and work-life balance affect work productivity as mediated by work discipline. This study used a quantitative method on 178 respondents from PT Widodo Unggas employees. Data analysis using the SEM-PLS technique with a path analysis approach and the correlation test. According to the findings of this study, human capital and work-life balance have an impact on employee work discipline, while work engagement has no impact on work discipline. Productivity is affected by human capital, work engagement, and work-life balance. This research also confirmed that work discipline also has an impact on productivity.

The modeling and optimization of concrete compressive strength produced by replacing natural aggregate (NA) with recycled coarse aggregate (RCA) and recycled asphalt pavement (RAP) aggregates was investigated. The materials used were cement, water, fine aggregate, and coarse aggregate (NA, RCA, and RAP). The RCA and RAP replaced NA at 20, 40, 60, 80, and 100% separately, and in combination, with a total of two hundred and forty (240) cubes cast, while the concrete compressive strength was determined after curing by complete immersion in water at 3, 7, 14, 21, and 28 days. The modeling and optimization was done with the aid of design expert (version 13) software, while the Analysis of Variance (ANOVA) was done using SPSS (Statistical Package for Social Sciences) version 23 and adopting the Least Square Difference (LSD) method. Results from the findings showed that the optimum 28 days concrete compressive strength are concrete produced with 20%RAP, 40%(20%RAP +20%RCA), 60%(30%RAP + 30%RCA), and 80%(40%RAP + 40%RCA) replacements which are not significantly different from the control concrete, however, 40%(20%RAP +20%RCA) and 80%(40%RAP + 40%RCA) concrete had compressive strength higher than the control concrete. Also, the 3, 7, 21, and 28 days compressive strength can be predicted with quadratic model, while the 14 days strength can be predicted with 2-Factor Interaction (2FI) model. The optimization result showed that by replacing natural aggregate with 10.0% RAP and 50.0% RCA, the 28 days compressive strength of the concrete was 33.74N/mm2.

Background: Blood is an essential fluid of the body. Safety of blood and blood products is of global concern in transfusion medicine especially as it concerns the transfusion of transmissible infections (TTIs). Objective: This study was aimed to established the prevalence of haemoparasites in voluntary blood donors at Livingspring Hospital, Igbogbo, Lagos State. Methods: A cross-sectional study with a quantitative approach carried out on all voluntary blood donors during lockdown, 2020. Blood samples were collected from 100 donors into EDTA containers with age range 18-50 years. Donors were made up of 75 males and 25 females. Samples were processed using Giemsa techniques and were examined microscopically for haemoparasites. Descriptive and inferential analysis were carried out at p<0.05 significance level with 95% confidence interval. Results: The overall prevalence of haemoparasites among donors was established at the rate of 35% (35/100). Of the 100 donors, 35% were positive haemoparasites, of which 33% of the donors were positive for Plasmodium falciparum while 2% were positive for Loa loa. However, findings were statistically not significant (p<0.05). Conclusion: It is imperative to screen blood samples to ensure safety of complete patient healthcare and service delivery.

The aim of this case study research was to examine how one experienced PE Lead Teacher in a specialist special school for children with social, emotional, and mental health issues learned how to implement the teaching games for understanding (TGfU) model into a unit of hockey lessons. The qualitative data collection methods consisted of two main methods, firstly there was the end of unit semi-structured interview of the PE Lead and secondly there were the Likert Scale student questionnaires which were completed on three occasions, before during and after the study covering sixteen hockey lessons over a four-month period. Using inductive data analysis indicated the experienced PE Lead was able to teach the principles of the TGfU model through a series of benchmarks which has been developed from the original model created by Bunker and Thorpe (1982) and further developed by Metzler (2011). The study has been able to show that the experienced PE Lead has been able to learn how to use the model through his own research and interest in the TGfU approach to learning and apply this to his PE lessons with students who have special needs. The findings have also shown that by using each of the TGfU model benchmarks the engagement, social behaviours and interest levels of the students have also improved. However, the study is limited to one model of learning (TGfU) and is focussed on a single experienced teacher of PE over a relatively short period of time.

The level of heavy metals in marine ecosystem has been intensively studied during recent years as these hazardous substances could be accumulated in the biota. Generally, the presence of contaminants in shellfish is as a result of human activities such as industrial, agricultural wastes, crude oil exploration and spillage and this has pose a significant threat to humans’ health and other animals feeding on them over the years. In this study, some heavy metals levels in shellfishes sourced from the rivers of Otuoke community in Ogbia local Government Area, Oporoma community in Ekeremor Local Government Area and Sangana community in Brass Local Government Area, all in Bayelsa state, were investigated and the samples were prepared according to Food and Agricultural Organization of United Nation FAO (1994) standard test methods. The total mean of cadmium, Lead, and mercury ranges between 0.00mg/g to 0.002mg/g in periwinkle, prawn and oyster gotten from the three communities and was compared with the WHO acceptable limit of 0.5mg/kg – 1.0mg/kg. This could have been due to increased rainfall during the period of this study which in turn increase water levels and hence reduced or dilute the heavy metal concentration and thus less risk of bioaccumulation or possibly that the oil producing communities from where the shellfish where obtained might have possibly be link to lack of cases of oil spillage over a recent past before the commencement of the study. This study therefore advocates that periwinkle, prawn and oyster which are shellfishes used for this study from the rivers in these communities are safe for human consumption with respect to heavy metals load especially within the raining season when this study was conducted.

With the advent of the Industrial Revolution 4 (IR4), many new challenges have emerged. One such issue is privacy and security. Millions of devices are now connected to the internet, and there is no concrete way to ensure that the user has authority (or) control over its data. This study addresses this challenge by drawing a theoretical framework for IoT software that can provide mathematical proof to the user regarding the privacy of the data. Such a certification would ensure that the data remains confidential as well as it will accelerate the rate of adoption of IoT technologies.

This study aimed to determine the percentage of a recreational physical activities and sports (PAS) practitioners or non-competitive athlete in Yaoundé city, and the risk of sudden death incurred. Seven hundred and ninety-three (793) men and women practicing recreational sports took part in this survey. The analysis of the variables of the socio-demographic, professional and clinical characteristics of those practicing physical activity ≥ 3 hours per week and those practicing physical activity < 3 hours was made. Data collection was carried out using a pre-established questionnaire, after obtaining an ethical clearance from the Ministry of Public Health. The average age of participants was 27.3 ± 10.6 years, they are mostly made up of men (56.2%). Five hundred and forty-seven (68.9%) said they practice physical activity at least 3 hours a week. Fifteen (15) participants or 1.6% declared to be carriers of a cardiovascular pathology and thirty-nine (39) or 4.9% are hypertensive. A large number (439; 55.6%) refrained from disclosing their clinical status or were unaware of it. The rate of recreational physical activities and sports practitioners is high in the population of Yaoundé. In this population, some practitioners are carriers of pathologies exposing them to sudden death. Knowledge of these data can contribute to taking appropriate measures to reduce cases of sudden cardiac death related to sports practice, a phenomenon increasingly observed in Cameroon.