Covid 19 is the global pandemic that continues to surprise us day after day with its atypical clinical expressions, and its variable systemic damage from one patient to another. We report 3 clinical cases of patients with covid 19, in whom we diagnosed diabetes for the first time. The evolution of their diabetes towards remission marks its particularity. This so-called “covid” diabetes reminds us of transient neonatal diabetes.

Introduction: The purpose of the study was to investigate the effects of backpacks on body posture and spinal morphology in children and adolescents, and the relationship between them and back pain in adolescents, in order to provide a theoretical basis for further research in this area. Methods: The literature on backpacks, body posture, spinal morphology and back pain was searched and the results were analyzed. Results: The studies mainly focused on the effects of backpack type, weight and position on their muscle activity; and the main muscles studied were upper trapezius, erector spinae, and rectus abdominis, while the studies on other muscles were still insufficient. Conclusion: Backpack type and method, backpack weight, backpack strap design, backpack position, and backpack time all have different effects on muscle activity in various parts of the adolescent body, and these effects may lead to back pain, which is one of the factors affecting spinal health that cannot be ignored.

One of the government's efforts to realize the highest health status and goals, especially for people who cannot afford it, is regulated in Law Number 24 of 2011 concerning the Social Security Administering Body. However, in practice, several problems were found, such as a tendency for the public to assume that the Social Security Administering Body for the Health Sector bears all the financing for health services and there is no guarantee of comfort received by the participants of the Social Security Administering Body for Contribution Assistance. This shows that the enforcement of legal protection regarding the rights of the poor as participants in the Health Insurance Contribution Assistance has not been realized from the perspective of human rights. The purpose of this study is to identify and analyze legal protection and problems for participants of the National Health Insurance Contribution Assistance Recipients (PBI), to identify and analyze the legal factors that affect the implementation of the National Health Insurance system for Contribution Assistance Recipients and to identify and analyze the reconstruction of Article 11 Law on the Social Security Administering Body for participants in the National Health Insurance for Contribution Assistance Recipients based on the value of justice. This study uses a type of research and a Socio-Legal (socio-legal research). The paradigm used is the Constructivism Paradigm to understand that the existing reality cannot be generalized to a particular context at a specific time. The results of the study show that it can be seen clearly both from theoretical studies and empirical studies, including a review of the products of laws and regulations as well as government policies and institutions in the context of the Welfare States and the government's effort to provide social security and social services to all its people in an integrated manner. fair. Legal protection for patients participating in the National Health Insurance Contribution Assistance Recipients (PBI) is an important thing because this is closely related to the handling and health services that will be received by patients. The implementation of legal protection for people who cannot afford has been implemented but is not optimal. The legal factors that most influence the implementation of protection for poor people in hospitals today are community factors, namely not being aware of the law and or not obeying the law, so there is no effectiveness. In addition, there are still differences in the health services received by patients participating in the Health Social Security Administering Body for Contribution Assistance Recipients with patients from the Social Security Administering Body for Non-Contribution Assistance Recipients. The Ideal Construction of the National Social Security System in the Health Sector Based on Welfare Values can be realized by reconstructing the law against Article 11 of Law Number 24 of 2011 concerning the Social Security Administering Body by reconstructing 3 (three) components, namely strengthening the legal substance component, strengthening the legal structure component and strengthening the legal culture component.

Increasingly expanding various actions that have been categorised as contempt of court, which threaten the authority of the court, it is necessary to regulate. The research method used is the normative legal method using statute, case, and conceptual approaches. This research is a legal study based on norms in force related to the contempt of court in existing regulations. The results show that all forms of actions that, in principle, disrupt safety, psychological and physical calm both inside and outside the trial, can be categorized as contempt of court. Although contempt of court has not been regulated clearly and firmly in statutory regulation many events can be classified as contempt of court. The scope of contempt of court in the justice system in Indonesia is very broad. The weighting of criminal sanctions is imposed based on the category of the seriousness of the crime committed by the defendant. Criminal weighting can be given if a crime fulfils special elements. Considering that the criminal justice process takes much time or is complex contempt of court can be used as a factor in increasing criminal sanction by the defendant so that there is no need for a new or separate criminal justice process to be held.

Background: One of the most effective instances of readily detected biomarkers diagnosing a very big health concern is the measuring of proteins in blood to represent heart damage. The idea of utilizing a blood test to reflect organ or cell harm necessitates a chemical that is plentiful in the target cell, can reach blood, has a suitable half-life in blood, and is preferably in a particular form that only reflects the target cell in tissue. Because contraction is the primary function of the myocyte, proteins involved in contraction or the energy required to sustain it should be suitable potential indicators. The work on diagnostic tests for myofibrillar proteins begins in 1978. Different key pieces of evidence fueled in the research. In Ist-year outcomes were identical in chest pain patients whose acute myocardial infarction (AMI) was ruled out by electrocardiography and cardiac enzymes, demonstrating that the existing diagnostic tools were not beneficial for risk prediction and treatment recommendations. Second, CK and lactate dehydrogenase isoenzymes were brought into clinical practice and demonstrated to have higher specificity and sensitivity than traditional tests. All of the biomarkers used to diagnose cardiac injury are involved in contraction or energy metabolism, but the markers evolved via trial and error, beginning with transaminases in the 1950s and ending with troponins in the 1990s. This background is discussed, along with observations on my experiences establishing CK-MB and Troponin I assays. Methods: 140 individuals with AMI are included who are diagnosed using WHO criteria. A cross-sectional study with purposive sampling technique is conducted in wazirabad institute of Cardiology. This research is last around 6 months. Before the examinations, blood samples are obtained from patients by vein puncture using syringes and preserved in clot tubes. The research includes patients experiencing chest pressure, tightness, or discomfort, shortness of breath, and irregular cardiac rhythms on ECG. Patients having a normal ECG are not included in the study. Different equipments are utilized to assess appropriate heart function and to obtain serum for the identification of various cardiac biomarkers. Result: The sensitivities of all biochemical markers change depending on the time of infarction, as previously demonstrated and expected from a patho-physiologic standpoint, the blood sample of all the patients was collected and used for further investigation in the Lab. In the current study, 140 patients are enrolled, and all of the patients who had a single episode of AMI had their ECGs taken. All of the patients' ECGs are abnormal. In compared to other Bio-Cardiac Markers, the Troponin –I has a higher ratio of patients, according to the present findings. When a person undergoes AMI, the first protein that is released is troponin-I. When these tests are conducted over a period of time, they provide us with a quick assessment of the severity of AMI. As a result of the current findings, patients have a higher level of Trop-I in their blood when they experience their first episode of AMI. In this situation, the patient should go to the nearest health care center's emergency room as quickly as feasible. Conclusion: The traditional enzymatic assays of creatine kinase (CK), CK-MB (activity), and lactate dehydrogenase are rapidly being replaced by mass measurements of myoglobin, CKMB, and troponin T and troponin I (Tnl) 1 " to achieve high diagnostic sensitivity and specificity within a few hours from the onset of tissue necrosis; the ultimate goal is the early and appropriate management of patients' conditions. We compared the diagnostic sensitivity and specificity obtained by measuring various biochemical markers, some of which are widely used, and concluded that Troponin I is the first cardiac marker that releases simultaneously after the first episode of AMI when performed as single tests and in parallel and serial modes.

Accreditation is one of the approaches to evaluate the quality of health care services, and it’s an essential requirement for the continuity of services. Nursing staff play a major role in the accreditation preparation, process and continuity. The study aimed to assess the nursing perception of the impact of accreditation on the quality of care and safety in a tertiary cardiac care center in the Eastern Province, Kingdome of Saudi Arabia. A cross-sectional descriptive research design was used. A convenient sample of 56 nursing staff was included. The study tool was a self-administered online questionnaire. It consisted of four major sections with 20 subscales rated from 1 to 5 on a Likert scale. Nursing documentation, patient medication information, healthcare-associated infection, leadership and support sections are all included. The study findings indicated that nurses have a 94.6% positive perception of the impact of accreditation on the patient’s safety. This perception was measured in accordance with the items related to international patients’ safety goals. Higher agreement was found on the items of nursing clinical documentation and medication safety process. The study findings support the overall positive impact of accreditation. The study further recommends exploring the nursing perception of accreditation impact in different settings.

Background: Cancer diagnosis can have an extensive impact on mental health and comfort. Depression and anxiety may hamper cancer treatment and recovery, as well as quality of life and survival. Cancer is an important incident in one's life which has substantial outcomes for patients and their families as well. The major psychological significance in cancer patients is depression that often takes less attention. Objective: The objective was to determine the prevalence of anxiety and depression among cancer patients and whether these conditions were associated with certain sociodemographic factors. Methods: It was a cross-sectional study. By convenient sampling technique, a total of 150 samples were selected. The patients were studied after histopathological confirmation of diagnosis of cancer. Sociodemographic and other data was collected by face-to-face interview using semi structured questionnaire. Data analysis was done by Statistical Package for Social Sciences (SPSS) version 26.0 and results were presented with appropriate graphs and texts. Results: The mean age was 46.5±9.5 years. 65.3% were male and 34.7% respondents were female. Male: female ratio 1.9:1. Moderate depression was higher in-service holder 53.8%. Among agriculture worker, 38.6% had mild depression symptom, within house wife 63.2% had mild to moderate depression symptom. No significant relation was found occupation with depression symptom (p>0.05). While moderate anxiety symptom was higher in-service holder 42.3%. Among agriculture worker, maximum 54.5% had moderate to severe anxiety symptom, within house wife 47.4% had moderate to severe anxiety symptom. No significant relation was found occupation with anxiety symptom also (p>0.05). Significant relation was found among income group with level of depression and anxiety symptom (p<0.05) as study showed both depression and anxiety were found more among higher income group population than lower income population. Conclusion: In this study both higher education and higher socioeconomic status were found to be predictors of depression and anxiety.

Background: White coat hypertension (WCH) is a condition in which people exhibit an elevation in blood pressure (BP) in a clinical setting, although they do not show such elevation in other settings. This study aims to provide new insight into determining the prevalence of WCH amongst patients with or without any cardiovascular risk. Method: This is a cross-sectional study of convenience sampling study design where 300 patients were involved based on their consultation to a Tertiary Healthcare Unit between November 2021 to March 2022 in Erbil city. Patients were classified according to the ESC into different categories of BP patterns by comparing the first BP reading that was taken at clinic with their average AMBP readings which were taken at home. Results: A total of 300 patients were included in the study where 58% of the population was male and 42% of the population was female. Of the population, 16% had WCH, 12.3% had sustained HTN, 59.3% were considered to be normotensive (NT), and 12.3% among them were categorized as masked hypertension. From the total of 47 patients that were diagnosed with WCH, 55.3% were male and 44.7% were female patients. The overall average Systolic Blood Pressure in WCH was 125.79±15.30 mmHg, and in Hypertensives it was 147.70±17.15 mm Hg with a P-value of <0.001. The Mean Arterial Pressure in WCH was 94.63±8.87 mmHg and in Hypertensives it was 112.16±13.62 mmHg with a P-value of <0.001. The average Pulse Pressure in WCH was 75.27±9.42 mmHg, and in Hypertensives it was 76.35±9.11 mmHg with a P-value of 0.001. Conclusion: WHC is significantly prevalent in Erbil city; therefore AMBP monitoring should be performed for those with certain indications to limit the prescription of unnecessary long-term medications with possibly significant side effects to patients with WHC.

Purpose: To compare the outcome of corneal collagen crosslinking (CXL) in conjunction with antimicrobial agents (AMA) to antimicrobial agents alone in the treatment of infectious keratitis. Design: Prospective comparative clinical trial in a tertiary hospital in India. Participants: 40 patients with infectious keratitis randomised into two groups of 20 patients each- Group 1 and 2. Methods: Group 1 patients underwent CXL in addition to antimicrobial therapy. The patients in Group 2 received only antimicrobial therapy. The slit-lamp characteristics of the corneal ulceration, visual acuity, time taken for healing, and complications were documented in each group. The t-test was used for statistical analysis. P values less than 0.05 were considered statistically significant. Results: The mean time taken for healing in Group 1 was 44.5±11.2 days and in Group 2 was 27.65±7.79 days. Analysis of various parameters revealed that patients undergoing CXL showed slower healing duration (p=0.00). Conclusions: Use of CXL in conjunction with AMA lowers the risk of complications, but also slows the rate of healing of ulcers.

Severe acute respiratory syndrome coronavirus 2 that causes coronavirus disease 2019 (COVID-19) is changing at a rapid pace due to accumulated mutations in the viral genetic code over time. As new variants of the virus continue to emerge and replace previous versions of the variants, therapeutics and vaccines are being constantly monitored and reviewed for their efficacy against the new strains. With the surge in new omicron sub-variants across the nation, U.S. Food and Drug Administration issued emergency use authorization to a new monoclonal antibody therapy called bebtelovimab replacing the previous sotrovimab that was effective against Omicron BA.1. The main objective of the paper is to review the current treatment options available to treat non-hospitalized mild-to-moderate COVID-19 caused by the new omicron sub-variants BA.2, BA.4, and BA.5. Scientists, pharmaceutical companies, and researchers have been proactive in conducting randomized, double-blinded, placebo-controlled clinical trials to test the safety and efficacy of therapeutics in managing COVID-19 in addition to testing the vaccine efficacy against new strains. The paper focuses on reviewing the results of these randomized controlled trials. The oral antiviral options paxlovid and molnupiravir, and intravenous (IV) bebtelovimab continue to show their efficacy against the new sub-variants BA.4 and BA.5. It is important for everyone to stay well-informed of the new treatment options and only opt for those medications that are currently authorized for use in treating mild-to-moderate COVID-19.

PT. Tirta Investama – Subang Factory is an industrial company engaged in bottled drinking water, background of this research is significant increase in product returns of 5 gallons over five years (in 2016 - 2020) from AQUA Group. Purpose of this study was to analyze the cost of quality due to defective products and their impact on the company's performance. This study uses the quantitative destructive method with the seven tools analysis method. The results showed that the increase in conversion costs / industrial costs, especially quality costs, has an impact on the company's performance must be improved.

The ultrasonic scalers are today becoming the most chosen form of dental polishing and cleaning. With the various researchers and lab tests done on them, it is steered clear of any side effects or invasive methodologies that might harm the patient in any manner. It works both on the soft and hard oral tissues have become the most widely used cleaning instruments among dental practitioners. Ultrasonic scalers use its vibrating power to eradicate different forms of dental plague and foreign components from the teeth. Through various on-field experiments and lab tests, it was made sure that these ultrasonic scalers work much better than any other primitive method for the same task. And that’s the major reason why it is so much in demand, ultrasonic scaling has become widely used for professional tooth cleaning. The aim of the systematic review is to assess the role of ultrasonic scaling on dental restoration. A computerized literature search was performed in following database including: Pubmed, the Cochrane Library, Google Scholar and Scopus databases from 1st January 2000 till January 2022. Studies determining the impact of ultrasonic scaling on dental restorations including randomized controlled trials, prospective and retrospective studies, and cross-sectional studies were included. After an initial search a total of 570 articles were identified. Then, 44 studies which were full-text articles were critically reviewed by independently for eligibility. Finally, 10 studies which met all the inclusion criteria were included in the review. The findings showed that out of all of the elements used, we can observe that the glass ionomers have had the chances of greater impacts. Further studies should assess the method of polishing for the removal of discolorations from ceramic restorations after ultrasonic scaling procedures and the possible side effects of polishing.

The purpose of the study is to investigate the Parental Background influencing Primary School Pupils Academic Performance in Maru Local Government Education Authority Zamfara State-Nigeria. The objectives of the Study are therefore to establish the parental economic factors and parental educational background influencing academic performance in public primary schools in Maru Local Government Education Authority. A descriptive survey research design was used in the study. The target population was 148 public primary school of Maru Local Government. Ten 10 primary school were purposively selected from total population. Validity of the instrument: face and content validity were validated by some experts, including one in test and measurement all from the faculty of education and extension service Usmanu Danfodiyo University Sokoto. To ascertain the reliability of the instrument, a test and retest was carried out in 2 schools out of the sample with an intervals of two weeks after which the two scores was compared using Pearson product moment correlation formula and the reliability index of 0.824 was obtained which indicate the agreement of the 2 test was good enough for usage. Study, indicated that many parents do not play their roles in terms of their children’s education as evidenced by low motivation, and parentsalso do not follow their children’s academic success. It was recommended that parents should discourage absenteeism of pupils in the school. Parent should devote more of their time to the upbringing of their children by providing academic materials.

The compressive strength and optimization of concrete produced by replacing cement with CSA and GSA was conducted in this study. The materials used were cement, water, fine aggregate, coarse aggregate, CSA, and GSA. The CSA and GSA replaced cement at 5, 10, 15, 20, and 25% in combination, with a total of seventy two (72) cubes cast, while the concrete compressive strength was determined after curing by complete immersion in water at 7, 14, 21, and 28 days. The modeling and optimization was done with the aid of design expert (version 13) software, while the Analysis of Variance (ANOVA) was done using SPSS (Statistical Package for Social Sciences) version 23 and adopting the Least Square Difference (LSD) method. Results from the findings showed that the CSA used in the study is a good reactive pozzolana, and the GSA is not a reactive pozzolana. Also, the increase in CSA and GSA content in concrete reduces its workability, and concrete compressive strength. However, cement replaced with 5%CSA-0%GSA gave the optimum 28 days compressive strength which is not statistically significantly from the control concrete and can be used to produce concrete of compressive strength close to the control. Further findings from the regression model showed that CSA-GSA concrete compressive strength significantly fits a linear model and can be used to predict the 7, 14, 21, and 28 days compressive strength of CSA-GSA concrete, while the optimized result showed that CSA and GSA replacement of cement at 3.29% and 4.45% respectively yielded an optimum compressive strength of approximately 22.31N/mm2.

The rapid development of Shi’a movement around the world involving several crisis in the Middle East become a major influencer on the Muslims in Malaysia. Though, its teachings and influence growth, but it was contradict with the Ahlul Sunnah Waljamaah (Sunni) teachings practice in this country. This development have become a serious problem when they dare to protest against the fatwa on banning Shi’a. Therefore, the purpose of this paper is to discuss the Shi’a deviance and the strategies to fight against its propaganda in Malaysia. The findings in this paper shows the Shiites deviation is from faith and practices aspects. At the same time, this paper found some of the key element regarding the Shiites propaganda among the people in Malaysia. Then, the paper concludes that the banned on Shiites movement in Malaysia is due to its extreme doctrine or teaching that effect the Islamic faith. Thus, the Shiites in Malaysia is not only seen as heresy, but it consider as a threat to the national security. Shiites dispersion is contagious in the country and need to eradicated as well as possible. This is because it’s a threat that able to clash the unity of Ummah and religious integrity as well as dividing the unity of the Muslims in this country.