This study aims to criticize the legal construction of multi-stakeholder unions which are not in line with the principles of Pancasila justice. From this critical study, new theories/ideas were generated regarding the system and arrangement of multi-stakeholder unions that are just Pancasila through the reconstruction of Ministerial Regulation no. 08 of 2021 concerning Unions with a Multi-Stakeholder Model using a constructivism paradigm with a normative juridical approach. This type of research is descriptive qualitative. This study uses 4 problem approaches, namely the statute approach, the historical case approach, the comparative approach to law, and the conceptual approach. The legal materials used in this research are primary legal materials and secondary legal materials with data collection methods through library research. Data analysis in this study used qualitative analysis. The results show that the legal construction of multi-stakeholder unions in Indonesia is not in line with the values and principles of Pancasila justice as There is a principle discrepancy between the substance or legal norms of the Regulation of the Minister of Union and Small and Micro Enterprises (PERMENKUKM) no. 08/2021 with the principle of kinship in the 1945 Constitution of the Republic of Indonesia, there is also conflicting legal substances or norms between the lower regulation (PERMENKUKM No. 08/2021) and the higher regulation (Law No. 25/1992 and the Job Creation Law). Then, The existence of material content or legal norms PERMENKUKM No. 08/2021 which exceeds the material limit of a ministerial regulation regulated in Law No. 12/2011 and Law no. 15/2019. Based on this, it is necessary to reconstruct a number of norms in Ministerial Regulation no. 08 of 2021 concerning Unions with a Multi-Stakeholder Model, reconstruction of legal structures or institutions is needed in the form of increasing the ability and understanding of the Ministry of Unions and Small and Medium Enterprises towards Unions and reconstruction of legal culture in the community and union managers.

The purposes of this study are to analyze and find the weaknesses of the Law on Narcotics Abuser in Indonesia Currently and How is the Reconstruction of the Law on Narcotics Abuser based on Benefit Value in a research that uses an Normative-juridical approach where The data collection method used is sourced from secondary data and primary data which was carried out using qualitative analysis methods. The results of the study show that the Weaknesses of the law on narcotics abuser are in the list of the grade of the narcotics contained in the narcotics law that are not up to date as some of the narcotics in the list have been removed in various countries such as Cannabis. This problem not only causes Cannabis Abuser Prisoned although their position should be as “victim” but also one of the factors that causes Overcrowding in Prison in Indonesia. The reconstruction as intended by the author are not in the form of substantial law reconstruction but rather a structural law reconstruction where the Narcotics Law Article 8 (2) which states that In limited quantities, Narcotics Category I can be used for scientific development purposes knowledge and technology and for diagnostic reagents, as well as laboratory reagents after obtaining Minister's approval on the recommendation of the Head of the Agency Food and Drug Supervisor need to be upheld higher and if necessary to add an extra paragraph in the law to appoint the ministry of health together with National Narcotics Bodies to create a Joint Research Bodies that are obliged to conduct research related to the use of narcotics. By using this approach, not only the law’s narcotics list of grade can be justified and are up to date, the overcrowding problem in the prison can be minimized.

This research was carried out to examine the relationship between selected physical fitness characteristics and shooting accuracy among high school basketball players in the Cape Coast Metropolis. Preliminary investigation revealed that the shooting accuracy of basketball players in the metropolis was not good compared to the standards set for players of their age category. Forty (40) basketball players comprising twenty (20) male and twenty (20) female, male with a mean age of 17.15, weight of 73.20, height of 1.79, and female also with a mean age of 17.15, a weight of 68.65 and height of 1.64 were randomly sampled and randomly assigned to experimental and control groups, respectively. The experimental group was taken through drills to improve on selected fitness variables while the control group went through a mini-clinic on passing and dribbling. The mini-clinic was used to occupy the control group for the period of training at a different venue as the experimental group went through specific drills intended to improve on selected physical fitness characteristics which were used as the bases for assessing improvement in shooting accuracy. Because the mini-clinic focused on passing and dribbling, it did not have any influence on their shooting hence difference was identified. Physical fitness tests were conducted using standardized tests; agility was tested with the Illinois agility test, balance with the flamingo test, coordination with the alternate hand wall toss test, power (upper body) was tested with the seated medicine ball toss test, power (lower body) with the standing broad jump, reaction time with the ruler test, and speed with the 40m dash. For shooting accuracy, the researchers adapted the tests used by Pojsic, Separovic, and Uzicanin which are static free throw, dynamic free throw, static two points, and dynamic two points. A dependent sample t-test and Pearson’s correlation were used for analysis. Overall results showed no statistically significant difference between the experimental and control group for both sexes for the physical fitness and shooting accuracy tests at the pretest but at the posttest, there was a statistically significant difference between the two groups. There was also a strong positive relationship between physical fitness and shooting accuracy among high school basketball players in the Cape Coast metropolis. The problem of shooting accuracy among high school basketball players in Cape Coast metropolis can be improved with a planned programme to improve on their selected game-related physical fitness variables.

Death and dying is a very interesting topic to study. It has however attracted very little historical, socio- cultural and anthropological interrogations. Among the pristine Bukusu people of Western Kenya, death was accorded numerous socio-cultural rituals that constituted coded meanings which may have only been understood in the realms of religion. This paper thus attempted an examination on how traditional religion was a key determinant in conducting death rituals in the precolonial setup of the Bukusu community that was devoid foreign cultural influence. The findings in this paper were however extracted from a Doctor of Philosophy Degree (History) thesis which will be submitted to Graduate School of Laikipia University by February 2023. The broader objective of the thesis has interrogated mortuary and funerary rituals of the Babukusu of Kenya from 1895 to 2010. Being a historical research, relevant information in the study was collected in the field through extensive Oral Interviews (abbreviated as O.I in the footnotes) which was corroborated with other secondary sources to ascertain the relevance of the information.

The Metamorphosis is a novella written by Franz Kafka. This novel tells about a young man named Gregor Samsa who has experienced alienation. This research aims to understand the effects of alienation experienced by Gregor Samsa as a major character in The Metamorphosis. Erich Fromm's theory about three mechanisms of escape is used to analyse the effort of Gregor Samsa in solving his psychological problem of alienation. Modern man usually uses three mechanisms of escape by Erich Fromm to reduce the feeling of fear and isolation of burdened freedom when they want to be free. This research uses qualitative research in which the data are in the form of words and sentences in this novella. This study applies the documentary method as the technique of data collection. The data can be taken from various sources, such as documents, books, and journals. This research shows that Gregor Samsa’s alienation has influenced his entire life, family, and society.

Background: COVID -19 has wide range of presentation, from asymptomatic infection to severe viral pneumonia and death. D-dimer >1μg/ml is one of the risk factors for mortality. CT chest plays an important role in early detection and monitoring of disease. Objectives: 1. To compare D-dimer value and CT chest findings in Covid-19 patients. 2. To study platelet count, PT, aPTT and CRP in Covid-19 patients. Methodology: RT-PCR confirmed Covid- 19 patients admitted in hospital investigated with D-dimer and CT chest were included in the study. Case details retrieved from medical records. Venous blood collected and plasma processed in coagulation analyser for PT, aPTT, INR and D-dimer. Platelet count was performed using auto analyser. CT findings were retrieved from radiology software (PACS). Statistical tests used were mean, percentage and Fisher’s exact test (SPSS Version 20). Results: During study period of January-June 2021, 38 patients were included. Mean age was 51.1±15.6 years and M:F ratio 2.8:1. 65.8% patients had comorbidities (25/38). D-dimer elevated in 60.5% (23/38) patients. CT showed 10.53%, 28.94%, 60.53% of patients had affected lungs of <15%, 15%-49% and ≥50% of the total area and showed significant association with D- dimer (P=0.018). 17.4% (4/23) patients with elevated D-dimer did not survive. 15.8% (6/38) patients had low platelet, 23.7% (9/38) had abnormal PT, 70.3% had abnormal aPTT and 89.5% (34/38) had elevated CRP. There was no significant correlation between platelet, PT, aPTT, CRP and D-dimer. Conclusion: D-Dimer is elevated in COVID -19 patients and shows significant association with lung involvement and can be used as prognostic marker.

Introduction: Bacteria that enter the bloodstream and mobile to the brain cord cause bacterial meningitis. The disease is less frequent in developed countries compared to developing countries. In Bangladesh, bacterial meningitis constitutes 25% and the case fatality rate was 14%. The mortality from meningitis is near 100% in untreated individuals and can still be up to 40% in children who received appropriate antibiotic therapy in developing countries. Aim of the Study: The study aims to investigate the specificity, sensitivity, and diagnostic accuracy of CSF-CRP in the diagnosis of Acute Bacterial Meningitis (ABM). Methods: An observational cross-sectional study was carried out in the Department of Pediatric Medicine, Dhaka Shishu Hospital (DSH), from 01 Jan-2017 to 30 Jun-2017. A total of 100 patients were enrolled in this study following the inclusive criteria. Data were collected using the predesigned semi-structured questionnaire. Verbal consent was taken before recruiting the study population. Completed data forms were reviewed, edited, and processed for computer data entry. Result: Among the study population majority of patients (43, 43.0%) were 0-2 years old. One-third of bacterial meningitis (35,35.0%) occurs commonly at an early age (0-2 years). Out of fifty- seven cases (n=57) of bacterial meningitis, twenty-two cases were culture negative and thirty-five cases were culture positive. In the case of bacterial meningitis, in fifty-one cases (51,89.4%) out of fifty-seven, the CSF CRP test was truly positive, with mean±SD 21.7±10.9, false negative were only six cases (6, 10.5%). In aseptic meningitis thirty-nine cases (39,90.6%) out of forty-three cases, the CSF-CRP test was truly negative, and false positive were four cases (4,9.3%). The sensitivity of CSF CRP in differentiating bacterial meningitis from aseptic meningitis was 89.47%, specificity 90.69%, & diagnostic accuracy was 90%. Conclusion: Bacterial meningitis is fatal and more communal in children under one year of age to sixteen years of age. Increased consciousness and initial gratitude and apposite antibiotic treatment can decrease morbidity and mortality. Diagnostic accuracy can be applied as the initial test for the diagnosis of bacterial meningitis.

Background: Fractures of the tibial plateau, which are intra-articular injuries of the knee joint, are often difficult to treat and have a high complication rate, including early-onset osteoarthritis. Various treatment options including proximal tibial plating with locking compression plates are available for the treatment of tibial plateau fracture. Objective: The purpose of this research was to evaluate the functional outcome of tibial plateau fractures treated with locking compression plating; a technique found to effectively reduce post-operative co-morbidities. Material and Methods: This prospective and observational study was carried out in Multicentral base with Department of Orthopedic Surgery, Rajshahi Medical College, Rajshahi, Bangladesh from January 2020 to June 2022. All patients (n=256) enrolled in the study for the study were included and treated with a locking compression plate for tibial plateau fractures (Schatzker III-VI) after receiving informed written permission. Patients were monitored continuously with clinically, radiographically, and functionally at 6-weeks and 3-6 Month, fellow-up after surgery. Results: In our study of 256 cases, the mean age was 37.77 ±15.65 years. Most of the cases were Schatzker type VI (161 patients) 63% and type III (89 patients) 35%. The average duration for fractures union was 23.4 ±2.1 weeks. Superficial wound infection was the common complication seen in (6 patient) 2% cases. At six months, the mean knee society score (KSS) was 85 ±7.22 and majority of patients (245 patients) 95% had good results. Conclusion: The radiological and functional outcome of a locking compression plate is quite excellent. Tibial plateau fractures in adults can be effectively treated with this implant.

Background/Purpose: Diabetes is a metabolic disease characterised by chronic hyperglycaemia, with disturbance of carbohydrate, lipid and protein metabolism, resulting from a defect in insulin secretion and/or action. The International Diabetes Federation (IDF) estimated in 2017 that 425 million people were living with diabetes worldwide. It is estimated that by 2045, 629 million adults will have diabetes. In Cameroon, a prevalence of 5.59% was recorded in 2018, regardless of gender [1]. In the Department of Dja and Lobo, an ethnopharmacological study was set up to identify and characterize the medicinal flower used in the management of metabolic syndrome. Material and methods: Surveys were conducted among 135 people. Data on medicinal recipes used in the management of diabetes, hypertension and obesity were collected according to a standardized framework. The plant samples mentioned were collected and identified at the National Herbarium of Cameroon and characterized. Phytochemical screening was performed on each species. Results: A total of 135 natives from six different villages were interviewed about plants used in the management of metabolic syndrome in the Department of Dja and Lobo. The study identified 85 species in 49 families. The fabaceae, asteraceae and flacourthiaceae families each had at least five species cited by the stakeholders who participated in our investigation. The medicinal plants inventoried totaled 7 biological types. In total 41 species were involved in the treatment of diabetes. The most used preparation methods were decoction and trituration. Phytochemical screening revealed the presence of flavonoids, Phenols, Polyphenols, Tannins, Saponins in almost all the extracts collected. Anthocyanins were extremely abundant in almost all extracts. Conclusion: The results obtained constitute a very valuable source of information for the region studied. The valorization of these plants and the determination of the health profile of the local populations of the Dja and Lobo department requires the establishment of modern processing units specialised in the manufacture of medicines.

Nanotechnology is widely used for the manufacturing of photovoltaic (PV) solar cells. Applications of solar technology are based in two forms; lithium-ion and lead-acid. These cells and batteries have the capacity to store a large amount of energy longer than other ordinary batteries. The mechanism for manufacturing solar cells usually arises from the combinations of layers of single-molecule thick sheets of graphene and molybdenum diselenide. In this fact, one of common example is the fine coating of graphene with zinc oxide nanowires. Solar based cells are incorporated into the modified forms for increasing their synthetic applications. These modified forms are copper indium selenide sulfide quantum dots. Perovskite solar cells are dominating in the scientific community due to their advantages and cheap sources of solar energy. These perovskite solar cells are also composed of different metals and other combinations in order to make them functional for different purposes. The most widely implemented metals are germanium, antimony, titanium and barium. Tin (Sn)-based perovskites allow the movement of ions and electrons and significantly in the surrounding environment. There is also need in the future for valuable and mechanical designing for nanotechnolgy and their usage in industrial and commercial applications.

Background: Dermatophytosis is a worldwide health-related problem, affecting 20-25% population globally. Once it was very easy to treat with either topical or systemic antifungal agents but now become a challenge for dermatologists because of increasing resistance against conventional antifungals fluconazole, itraconazole, and terbinafine with standard dosages and duration for the last few years in Bangladesh. Search for an effective new oral antifungal agent now become essential. Aim of the Study: To evaluate the efficacy and safety of the new antifungal agent voriconazole in the treatment of refractory and recurrent cases of dermatophytosis. Methods: The study was conducted in the outdoor patient department of Jahurul Islam Medical College Hospital, a rural-based tertiary care teaching hospital on 100 patients with extensive, recurrent, treatment failure cases of dermatophytosis. The clinical diagnosis was confirmed by KOH microscopic examination. Patients were given oral voriconazole at a dose of 200mg twice daily one hour after food for 4 weeks. The patients were followed up at week 2 to assess clinical response and any adverse effects from the prescribed drug. The final efficacy assessment was made at the end of week 4 with the combined evaluation of mycological results and the sum of clinical scores according to a 4-point physician assessment scale of 0-3 (0-absent, 1- mild, 2-moderate, 3- severe). Results: A total of 100 patients completed the clinical trial. Among them 52% were male and 48% were female. The 15-25 year’s age group was 34% and the 26-35 year’s age group was 24%. Majority of patients 56% had a duration between 6 months to <1 year. Of all patients, 100% had tinea corporis and tinea cruris was present in 85%. Involvement with outdoor work was present in 60% of cases. A Complete cure was seen in 82%, mycological cure was seen in 12%, and failure to treatment was seen in 6% cases. Adverse effects were seen in 40% of patients with visual disturbances in 27%, followed by headache and skin rash in 5% and 3% respectively Conclusion: Based on the result, it can be concluded that voriconazole is a highly effective and safe oral antifungal agent that can be used in the treatment of recurrent therapy-resistant cases of dermatophytosis.

Diarrhea is one of the major causes of infant and young children morbidity and mortality globally. It is characterized by passing of more than 3 watery stools within 24hr which is accompanied by loss of body fluids and electrolytes leading dehydration and death if not treated. Therefore, this study was aimed in assessing knowledge and use of Oral Rehydration Therapy (ORT) in the management of childhood diarrhea among mothers. A cross sectional descriptive study was conducted among 103 mothers living in Kambaza metropolis using a questionnaire for quantitative data collection. The data were analyzed using Statistical Package for Social Sciences (SPSS), version 20 and p-value <0.05 was considered statistically significant. The results showed that a significant proportion of respondents were below the age of 36 years (25-35years) with the mean age of 30±0.327 years and most of them (92.2%) were married. 81.6% of the respondents heard knowledge about ORT and majority of them (82.5%) indicated they know to prepare ORS/SSS. The use of ORT in the management of childhood diarrhea was also found to be high (82.5%) among the mothers. A significant portion of the mothers (95.1%) indicated already made ORS sachet was more effective in treating diarrhea than home-made SSS. There is no significant relationship between maternal level education and use of ORT in the management child diarrhea (p=0.476). However, a significant relationship exit between maternal knowledge on ORT preparation and its usage for management of childhood diarrhea (p=0.037). This study recorded high knowledge and use of ORT for management of childhood diarrhea among mothers of under-five children. Therefore, it recommended that maternal knowledge on use of ORT and its preparation should be encourage.

Commercial advertisements play a significant role to introduce or define a product, its quality and its uniqueness to a purchaser. The roles of advertisers are thus very crucial in the modern day cut throat competition. The present study has examined how advertisements have depicted women in popular commercials from different points of view. It is found from the study that women have been projected as mothers, sisters and friends as per the situational demand. In case of older women, nurture and care are depicted and it is shown how they play a pivotal role in their families and thereby maintain social balance. In case of middle-aged women, their love and care for their children remain the central point of focus; whereas in the case of young women, their charm and relationships are the point of focus. However, some advertisements focus on erotic side and depict women in such a manner which hurts the culture and balance of the society.

The aim of this study was to discuss the significance of microplate osteosynthesis in pediatric mandibular fractures. Patient and methods: Ten patients with age ranged between 1-10 years were collected from those attending the outpatient clinic of Oral and Maxillofacial Surgery Department, Al- kawait Hospital, Sana’a University. All patients that have mandibular trauma associated with either single or multiple fracture lines in the mandible were included in this study. Diagnosis of the mandibular fracture was achieved through history, clinical and radiographic examinations. All patients were treated by open reduction and internal fixation by 1.2mm microplate. Results: No signs of infection in or around the incision during fracture treatment were observed, and the soft tissue healing progressed normally. Clinical follow up was done every other day for two weeks and after three months postoperatively. Conclusion: Management of mandibular fracture in children by open reduction and microplate is an acceptable method for treatment with least morbidity and increase stability of displaced segment.

Breast tumour could be benign or malignant in nature, thus early detection is of the essence for good management outcome. Associated morbidity and mortality in relation to breast cancer, in particular, are of great concern. Among the different challenges in the management of breast cancer, cytopenia is commonly reported, while, associated blood transfusion dependence has received little attention. This study, therefore, looked into the features of breast cancer patients particularly with regards to disease staging and average blood transfusion needs. This cross-sectional descriptive study enrolled 46 female patients accessing medical care for breast tumour in Southern Nigeria. Bio-data and information on clinical assessment were obtained from patients’ case files. Blood sample was collected from each enrolled subject for assessment of carcinoembryonic antigen level by immunochromatographic assay method. Breast tumour was observed to be prevalent among women of reproductive age with a peak at the age range of 36-45 years. Majority of the cases (82.6 %) turned out to be malignant, while 17.4% were benign conditions. Advanced stage 4 cases accounted for 47.4% of the studied group. Increasing prevalence of mortality during therapy was recorded alongside advancement in age as well as stage of the cancer. The carcinoembryonic antigen level varied significantly across the various breast cancer stages. Stage 4 breast cancer showed significantly elevated mean value compared to both stages 1 and 2. There is prevailing late detection of breast cancer in the Nigerian population contributing to high mortality rate and more demands on blood transfusion.