Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome. It has been spreading rapidly worldwide, causing serious public health crisis. Although most SARS-CoV-2-infected cases have asymptomatic or mild-to-moderate diseases. This study was carried out to evaluate the prevalence of asymptomatic COVID-19 among Students of Ambrose Alli University, Ekpoma. A total of 100 Students were recruited for this study (50 males and 50 females). Ages were from 16 years upwards. 5ml of blood was drawn from each subject, 3 ml into an EDTA while 2ml was dispensed into plane tube for Elisa test of COVID-19 antibody dictation. The sensitivity and specificity of the Elisa kits used were 94.36% and 100% respectively. The full blood count was determined using Sysmex KX 21 Haematology autoanalyzer). Results of this showed that 48% of the subjects tested positive for COVID-19 antibody, while 52% tested negative. The mean white blood cells of COVID-19 antibody positive and negative subjects revealed 5.61±1.79x10/9 and 5.30±1.37x109/l respectively. There were no significant statistical differences (p>0.05) in the white cell, Red cell indices of subjects positive for COVID-19 antibody when compared with those negative for COVID-19 antibody. Also result shows that those positive for COVID-19, their platelets revealed significant (<0.001) lower count 234.1 ±151.1 x109/l when compared with those who were negative (250.0±152.7 x109/l). The study concludes that lymphocytes, neutrophils and mixed cell counts studied were lower in subjects positive for COVID-19 antibody while total white blood cell count was higher in positive group (p>0.05). There was no significant difference (p>0.05) in the WBC, LYM, MXD and NEUT of the subjects with respect to age and sex.

Background: Reduction in physical activity, irrespective of the cause, as well as increase in the prevalence of sedentary behaviours are strongly associated with the development of some of the most serious health problems adults face such as , diabetes and cardiovascular diseases. Consequently, the World Health Organization (WHO) recommends that adults should undertake regular physical activity. Many adults lack knowledge of the physical activity recommendations. The aim of the study is to determine the knowledge, attitude and physical activity level in post Covid- 19 lockdown among adult learners in South East Nigeria. Methods: The descriptive research design was adopted for the study. Researchers’ structured questionnaire on knowledge of, and attitude towards physical activities and the short form of the International Physical Activity Questionnaire (IPAQ) were used to collect data. Results: Though the adult learners possess high level of knowledge of physical activities (64.10 %), majority do not know the physical activity recommendations by the WHO, while only 58.46% showed positive attitude towards physical activities. Physical activity level of the respondents as reported through the short form of the IPAQ showed that 54.87 % are low, 26.84 % are moderate while only 18.29 % has high physical activity level. Conclusion: The adult learners had high level of knowledge of physical activity, positive attitude towards physical activity. This did not translate to high level of physical activity. Public health awareness and health talks on the benefits of physical activities and WHO physical activity guidelines and recommendations should be mounted by the institutions.

The purpose of this research is to examine and analyze influence of company size, and leverage on tax avoidance with company transparency as a moderating variable in mining companies listed on the Indonesia Stock Exchange in 2015 – 2019. Data is obtained by accessing the company's financial statement and annual reports through the company's website or www.idx.co.id. The research sample was searched by purposive sampling methode using criteria so that 9 sample companies are obtained for 5 years of observation (2015-2019). The data analysis methode used is the path analysis methode with Partial Least Square which processed using SmartPLS 3.0 software. The result of this research indicates that the size of the company has a significant effect on tax avoidance. Leverage has no effect on tax avoidance. Corporate transparency cannot moderate the effect of company size on tax avoidance, but corporate transparency can weaken the effect of leverage on tax avoidance.

This study's main goal is to evaluate the Janata Awash Program's implementation status in Rupandehi, Nepal, where the program is dispersed among 13 VDCs and 4 Municipalities (before readjustment of local level). Interviews and a questionnaire survey were undertaken with applicants for the program, local leaders, officers in charge of implementation, and the monitoring body in the study region with regard to selected, non-selected, completed, and unstarted construction. In the fiscal year 2073–1974 there were 2214 applicants, which appears to be a relatively high amount. Since there are so many of them and they live in diverse places, it would be foolish to assume that one strategy will work for all low-income groups' housing needs.

Rosuvastatin belongs to the HMG-CoA reductase inhibitor class of drugs (statins). The main aim of the present study was to formulate and evaluate time-controlled pulsatile release Rosuvastatin press-coated tablets. The core tablets were formulated by the Direct compression method. Coated tablets were formulated by the Press-coating technique. The drug delivery system was designed to deliver the drug at a specific time for the patient suffering from Hyperlipidemia. The core tablets containing Rosuvastatin, anhydrous lactose, and different ratios of super disintegrants like croscarmellose sodium, and sodium starch glycolate, among six core tablets were formulated, and they were evaluated for post-compression parameters like Weight variation, Thickness, Hardness, Friability, Disintegration, and In-vitro drug release profile, then the core was optimized by using different ratios of polymers such as Eudragit-S100, Eudragit-L100, and HPMC K4M, Ethyl Cellulose (1:2, 2:1 ratios). Totally four coating compositions were fixed and coated to core tablets by press-coating method, then they were evaluated for post-compression parameters like Weight variation, Hardness, Thickness, and In-vitro drug release studies were performed in 0.1 N HCl for 2 hrs, pH 6.8 phosphate buffer for 6 hrs and pH 7.4 phosphate buffer from the dissolution data the coat containing Eudragit-S100, Eudragit-L100 (2:1) combination shown best profile for pulsatile release of Rosuvastatin. The 10 hrs of lag time for the drug release and the drug release were depending on the effects of the composition of the polymers used.

The topic of Ethics, law and culture in a digital environment is new to Informatics, a subject supplemented in the 2018 Vietnamese general education curriculum. In primary schools, new textbooks for 3rd graders, including that of Informatics shall be introduced in the school year 2022 – 2023. It is essential to equip teachers and parents with basic knowledge to better understand this topic, thereby educating their primary-age children about cultural and ethical behaviors in a digital environment. In this paper, the author focuses on providing basic knowledge of personal information for the study and teaching of the topic "Ethics, law, and culture in a digital environment", which is covered by the Grade 3-designated subject of Informatics from the 2018 General Education Curriculum in Vietnam.

The main concern in this study is the low learning motivation of primary school children in Rejomulyo Village, which is brought on by the repetitive nature of the curriculum and the dearth of educators with a range of teaching styles. Offering incentives and icebreakers during lessons is one technique to enhance students' motivation to study. The goal of this study was to investigate whether rewarding and ice-breaking had any impact on their motivation to learn in Rejomulyo Village's public elementary school students, Lampung, Indonesia. This study was conducted in a quasi-experimental manner. A questionnaire and documentation methods were used in the data collection process. A t- test analysis was the method of data analysis employed in this study (independent sample t-test). The test's calculations reveal a strong impact of rewards and ice-breaking on the motivation to learn of Rejomulyo Village's elementary school students.

Human monkeypox is a zoonotic orthopoxvirus disease with a presentation similar to the smallpox. The frequency and geographical spread of human monkeypox cases have increased recently in most countries of world. The disease is endemic in Democratic Republic of the Congo, Central and West Africa, but presently spread to other nations of the world including India that too when the whole world is facing the Covid -19 pandemic. In this article the author focus on the various parameters related to the monkeypox, present status and the stigmatization.

When a kid's parents demand performance levels much beyond his or her mental, social, or emotional capacity, the result might be a syndrome known as "hurried child syndrome"—a collection of stress-related behaviors. In essence, parents overbook their kids' calendars, pressure them to do well in school, and demand that they behave and respond like small adults. Another factor is the state of trade at the moment. Nowadays, a lot of people that market to children are aware that their parents no longer control what kids consume for food, clothing, or entertainment. This reality is being exploited by the consumerist system, and it has an impact on kids. The hurried child syndrome is represented by the following statistics: Recent research on the effects of rushed kid syndrome shows that the suicide and homicide rates have tripled over the past 20 years, childhood obesity has grown by 50%, and 15–25% of young children are "failing" kindergarten. Millions of children receive medications in an effort to "manage" them better at home and in school. According to recent statistics, 40% of adolescent girls who engage in sexual activity will become pregnant by the time they reach maturity, and 70% of virgin girls will not be virgins. The leading cause of mortality for youths today is drug and alcohol abuse, but suicide rates are also rising. Five thousand youngsters commit suicide each year.

The concept of empowerment is broad and is frequently viewed as a way to give more power to the powerless in numerous aspects of life. However, the empowerment of patients seeking health care has received less attention. Consequently, this article aims to examine how the notion of empowerment is defined in the scientific literature pertaining to healthcare. This concept analysis was conducted utilizing the eight-step Walker and Avant approach (2014). The data resources used in the analysis were obtained from health-related literature retrieved from the CINAHL, PUBMED, and PsycINFO online databases. Four distinguishing characteristics, including Mutually beneficial connections, Knowledge and skills, Self-determination and shared decision making, and Sharing of social power, were retrieved from the analysis. This concept analysis demonstrated to both patients and medical practitioners the optimal method for initiating the therapeutic relationship. Empowerment can facilitate health professionals' practice and increase patients' and consumers' confidence and happiness with health services. Additional analysis can be conducted to get a fresh understanding of the concept, contributing to the body of health-related information.

Hepatic hemangioma is the most common benign hepatic tumor. Ultrasound is sufficient for diagnosis. Otherwise, magnetic resonance imaging is necessary. Surgical resection is indicated only in the rare case of complications or disabling functional impairment. We report the case of a hepatic hemangioma initially diagnosed as a gastrointestinal stromal tumor of the stomach, in which surgical resection allowed the disappearance of the painful epigastric symptomatology.

In order to know the mental state in elements of the municipal public security directorate of Tlaxcala, an observational and longitudinal study was carried out. 18 (31.5%) of 126 (68.5%) police officers who agreed to participate in the study were studied. A battery of tests made up of 18 general psychometric tests was applied to them. Derived from the diagnosis, 3 people of 31.5% were found, of which 17.46031746031% are elements (users) that would require special attention in terms of their current mental state, and 1 element that comprises 0.793650793650% is a healthy and "normal" element mentally. It is concluded in this study the importance that the police elements are valued in their mental health since the improvement of their professional praxis depends on it.

A Nonlinear finite element based ABAQUS modeling studies were conducted to evaluate the performance of exterior Beam Column Joint (BCJ) under quasi-static test loads. Six integrated BCJ models representing different configurations of beam reinforcement anchored in joint are verified by using a novel retrofitting technique called "Post Installation of Supplementary Anchorage" (PISA) by using headed bar as supplementary steel. The configuration of beam reinforcement anchored in column are described by straight bar,90 degree bend ,180 degree hook (confirming to design code IS456:2000) and single head, double head bars (confirming to ACI 318-19, ACI 352R-02 ) and 90 degree long bend of ductile detailing (as per IS 13920-2016). Two series (A&B) of integrated joint specimens representing conventional (series-A) and retrofitted anchorage (series-B) systems are modeled and tested by using ABAQUS software. The test parameters considered are configuration of anchorage system and presence of supplementary anchorage. The test variables representing nonlinear performance of retrofitted joint system are Von Mises stress conditions, Principal tensile stress, Moment-Rotation, Degraded stiffness, Crack mechanics and Damage index. The results shows good improvement of post failure conditions of exterior beam-column joint such as relocation of plastic hinge mechanism and failure mechanics of retrofitted joint system. Also the results validated with experimental program on typical specimens casted and tested. This study imparts useful information on implicit retrofitting methods applied by external means in exterior beam-column joint. It also promotes performance based design principles with viable construction practice.

Background: Covid-19 is caused by SARS-CoV-2 that effect human respiratory system. This has led to create pandemic situation throughout the world and became the reason for millions of deaths worldwide. For securing the lives of people pharmaceutical companies has rushed to develop vaccines. Some of the notable vaccines being developed include Sinopharm, Sinovac Pfizer, Moderna, Astrazeneca and Cansino. The efficacy of these vaccines varies however the companies claim 70-80% efficacy rate of these vaccines. The current study aims to determine and compare the efficacy of Covid-19 vaccines before and during the fourth wave of Covid-19 in Pakistan. The questionnaire-based survey throughout Pakistan was conducted via google survey form and data was recorded. 1050 responses were recorded in total. The data reveals that most commonly used vaccines in Pakistan were Sinopharm and Sinovac, Cansino. The overall efficacy of all vaccines was 96% before the fourth wave of Covid-19. Whereas, the efficacy of these vaccines got a major drop to 72.4% as soon as the fourth wave emerged in Pakistan.

Northanger Abbey is one of Jane Austen's six novels which contains rich connotation and profound implication. Female education is the theme of the novel. With the help of Gothic novels, Austen interprets the theme of female education in the framework of Catherine and Henry's love and marriage story, and explores how young men and women find their own marriage partners under the pressure of society and the times. Jane Austen expressed her progressive view of female education. She thinks that only relying on parents' education at home can not cultivate mature and rational qualified women. They also need to step into the society and read novels to get personal growth in these activities of communicating with others. In Austen's time, a popular educational concept strongly advocates that women should receive family education to ensure their physical and mental purity, and believes that novels will corrupt their hearts and lead them astray. Austen's view is progressive and positive at that time. She points out the importance of rationality to emotion and imagination, and defends the art of fiction including Gothic novels.