The majority of the world population prepares medicines from plants to cure diseases. Schinus molle linens is a multipurpose plant that has been used for various remedies as constituents of traditional medicine. The aim of this study was to investigate the chemical constituents and antimicrobial activity of methanol extract and solvent fraction extracts of the stem bark of Schinus molle. Powder of Schinus molle was extracted with methanol by using the maceration method and the fractions were obtained by successive fractionation of the methanol extract with n-hexane, chloroform, ethyl acetate, and n-butanol. Preliminary phytochemical analysis of the crude methanol extract revealed the presence of flavonoids, terpenes, anthraquinones, alkaloids, tannins, phenols, and saponins. In addition to this, the antimicrobial activity of crude and solvent fraction extract was tested against S. aureus, E. faecalis, E. coli, and C. albicans at a concentration of 90.0, 180.0, and 900.0 μg/ mL. The crude methanol extract and chloroform fraction exhibited greater activity against gram-positive, gram-negative bacteria and fungi. The n-hexane and n-butanol fractions showed the least activity against most test bacteria and fungi. The study showed that it is possible to inhibit the growth of bacteria and fungi at different concentrations.

Measuring prevalence of usage of performance enhancing drugs in Boxing, wrestling, and bodybuilding is difficult. However, to fit their initiatives, National Anti-Doping Organizations are interested in knowing the numbers so that their scarce resources are not wasted. The purpose of this study was to establish knowledge levels, attitudes towards the use of performance enhancing substances (PES), among athletes from boxing, wrestling, and bodybuilding federations in Kenya. The study utilized cross-sectional analytical research design. The study population comprised of 1900 athletes from the three sports disciplines with a sample size of 384 athletes. Close ended questionnaires were used as the data collection instrument. Data obtained from the respondents was coded and organized for analysis by use of SPSS version 25. Hypotheses were tested using one-way ANOVA and t-test at confidence level of 0.05. Post hoc analysis was carried out using Duncan Multiple Range Test where differences were found to be significant. Results on usage showed that majority of the respondents (74.2%) never used food supplements (FS) to improve sports performance. Many of the respondents (93.8%) had never used traditional herbs (TH) to improve sports performance. 91.9% never used PES to improve sports performance. Majority of the respondents (96.6%) indicated as never having been given food supplements by a coach, doctor, or physiotherapist to enhance performance. On supply of PES, 91.7% of the respondents had no information of if medical practitioner, local chemist, or sports agents supplied PES and methods. The results of one-way ANOVA showed that there was a significant difference in the use of FS, TH, PES, and Methods by athletes from the three sports disciplines, [F (2, 381) = 24.050, p < 0.000]. In conclusion and in light of the limitations of this study generally majority of the respondents did not use PES and methods. There were also significant differences in use of PES and methods across the different sports. The study recommended that sports federation officials from boxing, wrestling and bodybuilding should have a put proper structures for imparting knowledge and proper attitude on use of performance enhancing substances among athletes.

In this study, the optimum stabilizer content for a poor lateritic soil intended as subgrade material for a pavement was sought. The natural soil was first characterized and classified and the soil fall into the class of A-6 based on Nigeria General Specifications for Roads and Bridges (NGSRB) AASHTO soil class for pavement construction. The soil was stabilized at three binder points of 4%, 8% and 12% which coincided with specification limits for cement based on NGSRB with the range of 7-11% recommended for soils in the class A-6. The results from the compaction tests and unconfined compressive strength (UCS) tests show that the suitable stabilizer falls within the specified range of 7 – 11%. Binder contents/proportions of 4% RHA, 8% RHA, 8% (50R + 50O), 4% (60C/L + 40R/O), 8% (70C/L + 30R/O), 8% (0C/L + 100R/O), 8% (50C/L + 50R/O) gave the most promising results of MDUW and UCS. In other to carry out a comprehensive investigation of the properties of the soil to determine which of the promising binder contents/proportions would be most suitable as stabilizer for the soil, it was recommended that other qualifying tests of specific gravity, Atterberg limits, CBR, UCS, durability and permeability tests be carried out for these recommended binder contents/proportions.

This study was carried out to assess conflict and its management in Ekiti State University, Ado Ekiti, Ekiti state, Nigeria. It examined the causes of conflict in the institution in Ekiti State University, Ado-Ekiti. These were with the view to assessing causes of conflicts and its management in tertiary institutions. Primary and secondary data were used to evaluate the causes and consequences of conflict on the institution. The primary data were collected through administration of copies of questionnaire while Secondary data were obtained through textbooks, journals, internet document and official publications. Two hundred and three (203) copies of questionnaire were randomly distributed to the respondents which represented 10% of the total population, while one hundred and eighty-six (186) were retrieved and analysed (representing 91.6%). The data collected from the questionnaire were analysed descriptively using frequency distribution and standard deviation. This study revealed that communication gap (85.4%), late payment of remunerations (93.5%) and poor availability of facilities and equipment in the institution (84.9%) are the major factors responsible for conflicts between staff and management in the institution. The study concluded that conflict management had been ineffective in Ekiti State University, Ado-Ekiti, Ekiti State, Nigeria.

Thyroid lipomatosis is a rare disease, characterized by diffuse infiltration of the stroma by mature adipose tissue, leading to increased size of thyroid gland. The pathophysiology of diffuse proliferation of adipose tissue in the thyroid gland is unclear. Our study involves 2 cases with thyroid lipomatosis treated in surgical department B, Ibn Sina University Hospital. In the 2 cases studied, the average age was 50 years and the 2 patients were female. The 2 patients had consulted for a cervical swelling and the physical examination had found a goiter in both patients. They were treated with total thyroidectomy, and the postoperative follow-up was simple, with no deplorable complications. Pathological examination of the surgical specimen showed infiltration of the entire thyroid parenchyma by mature adipocytes, without any sign of hyperplasia, malignancy or amyloid deposition. Diffuse thyroid lipomatosis is considered a rare condition with about 20 cases described in the literature. This entity has no malignant evolutionary potential and the complications are of a mechanical nature.

Introduction: Guided prostate biopsy is still relevant in confirming the diagnosis of suspected prostate cancer. Objective: This study evaluated the role of Transrectal Ultrasound (TRUS) guided biopsy along with histopathological evaluation in the detection of prostate cancer on the basis of abnormal digital rectal examination (DRE) findings and elevated prostate specific antigen levels (PSA). Participants and Methods: This prospective study was undertaken among consenting men aged 40 years and above screened for prostate cancer at the University of Uyo Teaching Hospital using targeted, stepwise protocol including DRE, PSA and standard 12-core transrectal ultrasound guided biopsy technique. Biopsy samples were sent for histopathological evaluation. Findings were documented, analyzed and presented in tables and figures. Results: Among 437 participants, abnormal DRE findings, elevated PSA level above 4.0 ng/ml and abnormal TRUS findings were 17.2%, 21.1%, and 17.3% respectively. Of 44 participants who had prostate biopsies with histopathologic assessment, benign prostatic diseases were 24 cases (54.5%), slightly outnumbering malignant prostatic diseases seen in 20 (45.5%).The prostate cancer detection and prevalence rates were 45.5% and 4.6% respectively. Prostatic adenocarcinoma (45.5%), nodular hyperplasia (45.5%), basal cell hyperplasia (6.8%) and high grade prostatic intraepithelial neoplasia (2.2%) were identified histologic subtypes. Nodular hyperplasia was commonly associated with chronic prostatitis (80.0%). A significant association between DRE findings, outline of prostate, and tumour subtype was ascertained. Conclusion: Targeted screening protocol encompassing TRUS guided 12- core biopsy is a final arbiter in the diagnosis of prostate cancer and has a fairly high prostate cancer detection rate of 45.5%.

Objectives: All studies performed periodontal distraction with interseptal bone cuts but no one performed it without interseptal bone cuts. Therefore the aim of the present study was to evaluate and compare the effect of periodontal distractor with and without interseptal bone cuts on the pulp vitality of the retracted canines. Methods: The sample of the study consisted of 32 canines in 16 female patients (16- 21 years old) requiring extraction of bilateral maxillary first premolars and canine retraction. They were divided into two groups: canine retraction by periodontal distractor with distal interseptal bone cuts (Group I), canine retraction by periodontal distractor without distal interseptal bone cuts (Group II). After bilateral maxillary premolar extraction in both groups inter septal bone cuts was done in group I only. Then the periodontal distractor was cemented and activated twice per day in both groups. An electrical vitality test was evaluated before and after the distraction procedure. Results: None of the teeth reacted negatively to the electrical vitality test that was performed one month after the completion of the distraction procedure. There was no clinical sign of discoloration or pulpal pain in any tooth. Conclusions: Canine retraction was accelerated effectively by periodontal distraction technique either with or without distal interseptal bone cuts. The electrical pulp tester was positive in both groups.

Background: Women suffers 10 times more with thyroid disorders than men. Alterations in menstrual cycle alters thyroid function which could be either hypo or hyper thyroidism. Abnormal increase in serum prolactin level can cause disturbance in follicle maturation and corpus luteum function, and can lead to inhibition of normal secretion of GR hormone in hypothalamus which results in anovulation. The aim of the present study was to assess the thyroid and the prolactin levels among the women with dysfunctional uterine bleeding at tertiary care Hospital of western Rajasthan. Methods: An observational study was conducted for a period two years i.e from 2020 to 2022 in our institution at the gynaecology OPD with help of pathology department. 250 Patients with the complaints of dysfunctional uterine bleeding of age group between 25 to 70 years were included in the study. Estimation of Free T3, Free T4, TSH and prolactin was done by chemiluminescent immunoassay for the patients. Results: The mean TSH levels among the DUB cases was high. Similarly, hyperprolactinemia was found in cases and the mean prolactin levels were higher in cases. Significantly strong positive correlation between thyroid function and prolactin with p value <0.0001 was found.which indicates that as the TSH level increases prolactin levels also increases. Conclusions: Early detection of hypothyroidism in DUB cases can save the patient from recurrent curettage and at times hysterectomy. The financial implications of screening for prolactin/thyroid hormone abnormalities will have to be evaluated before a general recommendation can be made.

Background: Dysfunctional uterine bleeding is one of the most frequently encountered conditions in gynaecological practice world over and is defined as bleeding from the uterine corpus that is abnormal in volume, regularity and /or timing and has been present for majority of the past 6 months. This study was done to evaluate histology of endometrium for identifying the endometrial causes of DUB. Material and Methods: This was a retrospective study done at Dr S N Medical College, Jodhpur, Rajasthan on 250 patients who presented with DUB from June 2020– September 2022. The endometrial changes were observed by reviewing and studying the histological slides, prepared through routine processing channels which includes fixation, grossing, tissue processing, dehydration, paraffin embedding, cutting and H&E staining procedures. Results: The commonest endometrial pattern was proliferative pattern in 145(58.00%) cases. Followed by secretary pattern in 34(13.60%), disordered proliferative pattern 19(7.60%). Cystic Dilatation11 (4.4%), Simple Endometrial Hyperplasia 9 (3.6%), Atrophic Changes 9(3.6%), Late Proliferative Pattern8 (3.2%), Early Secretory Pattern 6(2.4%), Hyperplasia without atypia5 (2%), Arias Stella reaction3 (1.2%), Cystic Hyperplasia1(0.4%). Conclusion: The incidence of proliferative pattern was significantly high in this study, suggesting an early presentation of these patients.

Oral health is essential to quality of life because it promotes social and physical well-being and serves as a reflection of general health. According to some estimates, dental and oro-dental conditions are the most prevalent illnesses in the world. One important known predisposing factor for various oral illnesses is poor oral hygiene. Since the beginning of recorded history, mankind has suffered from oral diseases in all of its manifestations. Ancient Chinese, Greek, Roman, Egyptian, Arabic, and Indian surgical and medical treatises all discuss mouth illnesses at some point. Many renowned Unani physicians have too mentioned about various oral diseases and unhygienic conditions in their respective books. They have clearly mentioned how to maintain oral health and treat various oral conditions in their respective rich Unani texts. Present review paper is an attempt to throw some light over oral hygiene, its historical background and diseases which occur due to poor oral health light of the Unani literature.

Breast milk is a natural liquid’s food given to babies who are between one-day old to about 2 years old depending on mothers and locations. The aim of this study is to investigate Pattern of Breastfeeding amongst Mothers and its Physiological Effects on Infants in Rural Areas of Rivers State. This is a cross-sectional study involving 111 lactating mothers who are within the age of 18 to 42 years. A well-structured questionnaire was administered to participants. Each participant had one questionnaire to fill appropriately and independently after instructions were given to them by the researchers. The study lasted for a period of 9 weeks. The study revealed that 17(15.30%) had primary education, 64(57.70%) had secondary education while 30(27.00%) had tertiary education. Occupational distribution of respondents shows that 10(9.00%) were civil servants, 61(55.00%) business class while 40(36.00%) were farmers. The results also, shows that 98(88.30%) were nursing mothers while 13(11.70%) were not. The results of breastfeeding pattern of respondents show that 11(9.90%) used breast milk alone, 32(28.80%) breast milk +water, 2(1.80%) breast milk + pap, 31(27.90%) breast milk +NAN or others in this category +30(27.00%) breast milk + solid food while 5(4.50%) employed pap alone. The level of awareness of the respondents about exclusive breastfeeding revealed that 78(70.30%) said YES while 33(29.70%) said NO, that they do not know about exclusive breastfeeding. 90(81.1%) of the respondents do not carry out exclusive breastfeeding and 21(18.9%) carried out exclusive breastfeeding. The duration for breastfeeding among mothers are 5.4% (6 months), 13.5% (5 m0nths), 37.8% (3 months), 43.2% (none).

Climate change is the single greatest threat to human health, and medical professionals around the world are already taking action to mitigate the health effects brought on by this developing crisis. In order to avoid catastrophic health effects and the millions of fatalities that would come from climate change, the Intergovernmental Panel on Climate Change (IPCC) thinks that the increase in global temperature must be kept below 1.5°C. Some global temperature increases and other climate effects are already unavoidable due to historical emissions. Every additional tenth of a degree of global warming will have a significant negative impact on people's lives and health. It is thought that even a rise of 1.5°C is unsafe.

Summary: It is important to estimate the aboveground biomass and carbon stocks of trees with non-conforming trunks in the forests of the central Congolese basin to plan resource management and to assess the contribution of these forests in mitigating the effects of climate change and, this within the framework of conservation at the scale of a reserve, that for Measuring, Reporting and Verifying forest carbon stocks within the framework of national strategies for the reduction of greenhouse gas emissions linked Deforestation and Forest Degradation (REDD+). This study aimed to set up a protocol for estimating the aerial biomass and the corresponding carbon stocks of trees with particular architecture in the Yasikia forest. To succeed, a dendrometric study was carried out for all trees with non-compliant trunks. Dendrometric data were collected on 189 trees divided into 9 families and 20 species. The results of this study show that it is preferable to use the equivalent diameter for a good estimate of the biomass because taking the diameter at the end of the buttress or above, underestimates the quantity of biomass for a tree with a trunk not compliant. The equation used to estimate the woody biomass from different diameters was that of Brown et al., (1989). The results of this study show that it is preferable to use the equivalent diameter for a good estimate of the biomass because taking the diameter at the end of the buttress or above, underestimates the quantity of biomass for a tree with a trunk not compliant. The equation used to estimate the woody biomass from different diameters was that of Brown et al., (1989). The results of this study show that it is preferable to use the equivalent diameter for a good estimate of the biomass because taking the diameter at the end of the buttress or above, underestimates the quantity of biomass for a tree with a trunk not compliant. The equation used to estimate the woody biomass from different diameters was that of Brown et al., (1989).

Introduction: Intramedullary nailing is a commonly employed procedure for treating distal tibial fractures. The two primary approaches for this procedure include the suprapatellar and infrapatellar techniques. Despite their widespread use, there is ongoing debate about the relative merits and drawbacks of these two approaches. Aim of the Study: The aim of this study was to assess the comparison between suprapatellar and infrapatellar approaches for intramedullary nailing of distal tibial fractures. Methods: This cross-sectional study was conducted in Department of Orthopaedics Surgery, Brahmanbaria Medical College Hospital, Brahmanbaria, Bangladesh, during the period from December 2020 to December 2022. Total 120 patients with intramedullary nailing of distal tibial fractures were included in this study. All the patients were divided into two groups; Group A comprised of 60 patients treated by suprapatellar approach and Group B comprised of patients treated by infrapatellar approaches. Result: For age, the mean age in Group A is 42.3 years (SD± 9.8 years), and in Group B it is 44.7 years (SD±10.3 years). In terms of sex, male predominance was seen in both groups. Surgical characteristics like surgical time (68.5 vs 74.2 mins), blood loss (58.4 vs 63.7 ml), and fluoroscopy number (15.7 vs 18.9) were significantly less in Group A. Post-operatively, Group B reported more pain (VAS score: 27.1 vs 18.7), while Group A had better range of motion (18.3 vs 17.1) and knee functionality (Lysholm score: 84.6 vs 80.9). Group B showed better foot and ankle functionality (AOFAS score: 94.4 vs 91.3). Fracture healing time was similar (24.5 vs 24.7 months). Fewer patients in Group A experienced complications like fracture deformity, malalignment, and surgical site infections. Conclusion: The suprapatellar approach may be the preferred nailing technique for treating distal tibial fractures compared with infrapatellar approach.

Background: Preeclampsia, gestational diabetes, and premature delivery are three obstetric problems related with high iron reserves during pregnancy. Few studies have found an association between preeclampsia and higher serum ferritin levels, however, this finding was not convincing. Objectives: The aim of this study was to assess the variation in the levels of serum ferritin and serum iron level in preeclamptic Bangladeshi women compared to healthy pregnant women. Methods: This case control study was carried out in the Department of Obstetrics and Gynecology, Bangabandhu Sheikh Mujib Medical University (BSMMU) during October 2018 to September 2020. A total of 94 pregnant women between 18-40 years of age were included in this study in her 32 weeks to 38 gestational weeks. Among them 47 diagnosed case of preeclampsia and rest 47 healthy pregnant women were consider as control. Purposive sampling technique was followed. After taking consent and matching eligibility criteria, data were collected from patients on variables of interest using the predesigned structured questionnaire by interview, observation, clinical examination and hematological investigation of the patients. The serum ferritin and serum iron level were measured in Department of Biochemistry in BSMMU. Statistical analyses of the results were be obtained by using window based Microsoft Excel and Statistical Packages for Social Sciences (SPSS-22), where required. Results: Serum ferritin in preeclamptic women was (124.54±32.14 ng/ml), versus (50.83±2.53 ng/ml) in the control group with P-value (0.001). Serum iron in preeclamptic women was (110.19±23.62µg/dl), versus (105.15±26.6 µg/dl) in the control group with P- value (0.334). Almost three fourth (74.5%) patients had serum ferritin >120 (ng/ml) in case and 17(36.2%) in control. The difference was statistically significant (p<0.05) between two groups with OR= 5.15 (95% CI 2.12-12.47). There was a positive significant Pearson’s correlation coefficient between serum ferritin and each systolic and diastolic blood pressure (r=0.561, p<0.001 and r=0.556, p<0.001 respectively). Serum ferritin level increases significantly in preeclamptic women. There was no significant difference in serum iron levels between the preeclamptic women and control groups. Increased level of serum ferritin may play a role in pathogenesis of preeclampsia. Conclusion: Preeclampsia as one of pregnancy related complications is a notable burden of adverse health. This case-control study demonstrated that preeclampsia is associated with high serum ferritin levels, and that in preeclamptic women, serum ferritin was positively correlated with blood pressure.