Background: Acne vulgaris is a common dermatological problem. Acne is most commonly found in adolescents, caused by increased androgens in both sexes. It is usually caused due to Propionibacterium acnes. Minocycline is a newly introduced drug in treating acne vulgaris. On the other hand, it is assumed that azithromycin having a long half-life like can be very effective with better compliance in treating acne vulgaris. But we have not enough research-based comparative data regarding this issue. Objective: The objective of this study was to compare the efficacy and safety of azithromycin pulse therapy with minocycline in treating acne vulgaris. Methods: This was a prospective, comparative study and was conducted in Department of Dermatology, Naogaon Medical College, Naogaon, Bangladesh, during the period from January 2021 to December 2021. In total 80 patients with moderate-to-moderately severe (Grade II and III), acne vulgaris were included in the study population. Patients were randomly assigned to two treatment groups of group A & group B respectively. In group A, there were 25 patients received 500 mg azithromycin once a day for 3 days per week as pulse therapy along with 0.05% topical tretinoin for 3 months whereas in group B, there were another 25 patients received 50 mg minocycline twice a day along with 0.05% topical tretinoin for 3 months. All data were processed, analyzed, and disseminated by SPSS version 23.0 and MS Office program. Results: In this study, group A (Azithromycin) between baseline and final score distribution we found a significant correlation (P=0.023). On the other hand, in group B we did not find any significant correlation (P=0.073). In analyzing the changes in severity score of acne from baseline to the final assessment of both groups we observed, in group A at baseline 15%, 38%, and 48% of participants had the score points 2, 3, and 4 respectively whereas in the final stage 63%, 30%, and 8% participants had the score point 1, 2 and 3 respectively. So, in group A between baseline and final score distribution, we found a significant correlation (P=0.023). On the other hand, in group B at baseline 10%, 40%, and 50% of participants had the scored points 2, 3, and 4 respectively whereas in the final stage 65%, 28%, and 8% of participants had the score point 1, 2 and 3 respectively. In group B between baseline and final score distribution we found P value 0.073. Conclusion: In this study, the efficacy of both azithromycin pulse therapy and minocycline was found satisfactory. But as per the findings regarding the safety profiles, we can conclude that minocycline is safer than azithromycin pulse therapy in treating acne vulgaris.

Every tooth in the dentition can show very unique root anatomy along with variation in the number of canals in each root. The failure rate of nonsurgical root canal treatment is higher in the mandibular premolars due to difficulties in finding accessory canals explained in numerous studies. Clinicians should be aware and keep abreast with the complete assessment of the anatomy and morphology of the root canal system for a favorable treatment outcome. This case report illustrates root canal treatment for a rare case of a C-shaped with four root canals in the mandibular second premolar identified under a microscope and cone-beam computer tomography (CBCT) scan. This incidence has never been reported in the literature so far.

This paper explores the ways to reconstruct spiritual balance in William Faulkner’s novel The Sound and the Fury. This paper also elaborate on the social implication of the construction of spiritual balance.

Introduction: Urinary tract infection (UTI) is the third most common infection during childhood and considered as an important risk factor for the development long-term complications. It was aimed to look into the demographic characteristics, clinical presentations, and antimicrobial resistance among children hospitalized for UTI. Methods: This cross-sectional observational study was conducted at the Inpatients Department of Uttara Adhunik Medical College and Hospital, Dhaka, Bangladesh. The study duration was 2 years, from July 2017 to June 2019, during which period, a total of 90 children with urinary tract infection visiting the study place were included in the study, following the inclusion and exclusion criteria. Result: The age of the participants ranged from over 1 months to 5 years., with majority (55.56%) being between the age of 2-5 years. The male to female ratio was 1:1.73. Fever was the commonest presenting symptom in participants, with 87.78% prevalence, followed by vomiting in 80% of the participants. The commonest organism cultured in this study was E. coli (80%), followed by Klebsiella spp. (20%). Isolated pathogens were highly sensitive to Amikacin (100.0%), Meropenem (100.0%), Imipenem (97.0%) and Nitrofurantoin (90.9% - 100.0%), moderately sensitivity to third generation Cephalosporine and highly resistant to Ampicillin (75.0 - 78.8%), Amoxiclav (72.7% - 87.5%) and Cephalexin (81.1% - 87.5%). Conclusion: The proportion of urinary tract infection in females was higher than males. Most patients presented with more than one symptom but most commonly presented with fever. E. coli was the most common isolated bacteria in hospitalized children with a principal diagnosis of UTI. Most of the isolated pathogens were highly resistant to ampicillin, cotrimoxazole, and highly sensitivity to amikacin, nitrofurantoin and meropenem.

Composting is a technology for recycling organic materials in order to achieve enhanced agricultural production. Composting proceeds under controlled conditions in compost heaps and pits (Müller-Sämann, 1986). Heaps should have a minimum size of 1 m3 and are suitable for more humid environments where there is potential for watering the compost. The ratio of C to N in the compost pile is important for optimizing microbial activity. In this article, we will compare and contrast various composting techniques to examine the impact of composting on the environment. The composting process is impacted by temperature, Different composting techniques have an impact on both the physical characteristics of compost and the chemical composition of compost. Additionally, it will analyze Carbon and Nitrogen ratio. Which will enable us to comprehend how composting affects the atmosphere.

The article reviews economic security as an important aspect of the country's economic development. The article analyzes one direction of economic security - energy security. Within the framework of energy security, the importance of setting up LNG terminals is discussed. The article explores the challenges facing European countries in the supply of energy resources and the opportunities for diversifying energy markets. In the above context, the possibilities and perspectives of arranging LNG terminals are discussed, which will help Europe to improve its energy independence and economic security.

Economies with more active stock markets develop faster over successive decades. Such development remains attainable even after adjusting for various other factors underlying economic growth. Sierra Leone is one country whose stock market is now more than a decade old but remains poorly active. The number of listings as well as participation in the stock market remains low and insignificant. The study made a light review of the development path of the stock market in an effort to identify the derailing issues and suggesting ways to resolve. Through the review, it was obtained that there exist combinations of factors hindering the growth of the stock market. Inadequate support from the government has been identified, the privatisation concept was never implemented to the expected level, nature of business in the economy being mainly family-oriented and single proprietors, low levels of awareness of the general populace to issues of stock exchanges, limited participation by foreign investors, and high levels of corruption all are impacting factors. Significant reforms have to be made in the regulatory environment. Privatisation journey should be pursued effectively to improve listing by large firms. Foreign participation in the stock market elevated to some significant levels. The economy should continue to address issues of corruption so as to minimise its impact to institutional development. Public awareness should be enhanced to improve stock market participation by natives. Policies that promote foreign direct investment should be implemented. Management of political climate remains crucial for investors to have confidence and trust in their investments thereby attracting more for further development. Policy makers should walk the talk and demonstrate highest levels of commitment.

The purpose of this research is to develop IPR as joint property and how to distribute it after divorce based on justice. The method used in this research is socio-legal (Socio-legal Research). This study uses primary data and secondary data. Meanwhile, the technique of collecting data is through library research and field studies analytical descriptive data analysis. The results of this study indicate that this research also finds a new legal norm/rule: that the economic value obtained from all types of intellectual property rights, namely Copyrights, Patents, Trademarks, Trade Secrets, Industrial Designs, Plant Variety Protection, Layout Designs of Integrated Circuits registered during Marriage becomes joint property of husband and wife as long as it is not stipulated otherwise in the marriage agreement and the distribution after the marriage breaks up each gets half as long as husband and wife carry out their responsibilities, roles and duties properly as head/housewife, whereas if husband and wife are not/less able to carry out their duties properly responsibilities, roles and duties properly in the household, then the distribution is in accordance with the size of their contribution in the household and the process of creating/discovering IPR. The results of the distribution, either in a decision or an agreement in front of an authorized official, must be recorded at the Directorate General of Intellectual Property Rights, because the transfer of Economic Rights of Intellectual Property Rights only has legal consequences for third parties after being registered at the Directorate General of Intellectual Property Rights. Legal Structure Side, increasing knowledge, understanding and experience of law enforcement in the field of intellectual property rights through formal education, training, certification, seminars, workshops, library access, field practice and other means. Legal Culture Side, increasing public knowledge and understanding in the field of IPR through legal education, both formal and non-formal.

Agreement financing with guarantee fiduciary there is clause stating _ that if debtor no pay off the debt or no Fulfill his obligations to creditor so without through court more formerly creditor entitled and giving power substitution creditor for To do necessary action _ what if see by constitutive and productive no after with substance Article 23 paragraph (2) and Article 36 then writer aim for first analyze Regulation Legal Protection for Debtors and Parties Third In Agreement Credit with Object Guarantee Fiduciary Not yet Realize Score Justice , Second for analyze Protection Law For Debtor And Party Third In Agreement Credit with Object Guarantee Fiduciary moment this , third for To do Reconstruction Regulation Legal Protection for Debtor Dan Party Third In Agreement Credit with Object Guarantee Fiduciary Not yet Realize Value of Justice Method Study this is study qualitative with approach sociolegal research paradigm study constructivism. As for the findings study first Protection Regulation Law For Debtors and Parties Third In Agreement Credit with Object Guarantee Fiduciary Not yet Creating Value Justice In Thing divert , pawn rent , share results to the other party The object that becomes object Guarantee Fiduciary because existence assessment related with debtors and parties third second weaknesses Regulation as Protection Law of Sharing Debtors and Parties Third In Agreement Credit with Object Guarantee Fiduciary Not in line with existence agreement written from receiver fiduciary yang regulated in Article 23 and Article 36 of the Law Guarantee Fiduciary. Third Reconstruction Regulation Legal Protection for Debtor Dan Party Third In Agreement Credit with Object Guarantee Fiduciary Not yet Realize Value of Justice a) Reconstruction score justice regulation Legal Protection for Debtor Dan Party Third In Agreement Credit could increase protection law for debtor productive and constructive b) reconstruction norm there is Article 23 Giver Fiduciary prohibited transfer , pawn , rent and perform contract work for results to the other party The object that becomes object Guarantee Fiduciary who doesn't is object supplies , except with agreement written more formerly from Receiver Fiduciary . Article 36 becomes 2 paragraphs which mention paragraph (2) Criminal as intended _ in Article 35 and Article 36 paragraph (1) in Constitution this is offense complaint.

The family is the first social environment known to humans. The family is a social institution that functions to improve all the abilities that exist in each individual. However, it is not uncommon for families to have cases of irregularities or illegal activities that cause misery or suffering and are carried out by members of one family against other family members such as molestation, rape, and even leading to murder. This situation is commonly referred to as Domestic Violence or more commonly abbreviated as domestic violence. The formulation of the problems in this dissertation research is: 1) Why is the regulation of legal protection for victims of criminal acts of domestic violence not fair? 2) What are the weaknesses of the current legal protection regulations for victims of criminal acts of domestic violence? 3) How is the reconstruction of legal protection regulations for victims of domestic violence crimes based on the value of justice? The research method uses a constructivist paradigm, with a sociological juridical approach. Methods of data collection by observation and interviews, with qualitative analysis data analysis method. The results of the study are 1) Regulation of legal protection for victims of criminal acts of domestic violence has not been fair, it is worth considering who has the most initiative among couples in the household to commit acts of violence, including the scale of differences in physical strength and ability between husband and wife and seriousness in using physical force. Most women are victims of violence perpetrated by people who are closely related to them. Domestic violence is generally perpetrated by men against women, generally violence by husbands against wives. 2) Weaknesses of legal protection regulations for victims of criminal acts of domestic violence at this time in terms of legal substance, law enforcers in carrying out law enforcement are only oriented to legal certainty, not legal justice. From the aspect of the legal structure, the synergy between the apparatus has not been optimal, the weakness in this case since the enactment of the PKDRT Law in 2004, there are still many cases of violence against women that occur in society and many are even unsolved. In terms of legal culture, the factors behind domestic violence can be identified due to gender and patriarchal factors. 3) Reconstruction of Law Number 23 of 2004 concerning the Elimination of Domestic Violence by changing and adding imprisonment and fines in Article 44, and the second reconstruction by adding the value of justice to Article 54.

Since the outbreak of the Anglophone crisis in 2016, media professionals and ordinary people in Cameroon have been constantly producing hate speech via all forms of media, especially the social media platform called Facebook. This is believed to have far reaching consequences on the targeted individuals, groups and on national unity at large. This paper investigates how hate speech is represented in some posts and comments by Cameroonians on Facebook during Anglophone crisis. Data was gotten from some popular Facebook ‘groups’, ‘pages’ and the ‘personal walls’ of some Cameroonian activists. The paper reveals that hate speech for the most part on Facebook during the Anglophone crisis in Cameroon is based on ethno-political groupings, represented through the use of inclusive/non-inclusive pronouns, and words and expressions that excite hatred such as terrorists, Ambafools/Ambafrogs; Anglofou/Anglofools; Graffi; Cam no go; Bamileke Marquissard; La Republic/LRC; Francofools; and CPDM monsters. These words and expressions are further intensified through the use of deictic expressions and several demeaning adjectives, metaphors and similes. To solve this problem, the paper proposes some alternative words and expressions that can be used by Cameroonians both online and offline to reduce the rate of hate speech in Cameroon. The paper firmly holds that if work is done for the social and cultural transformation of all the people of Cameroon, then the usage of hate speech in Cameroon during and after the Anglophone crisis will be reduced.

The effect of varying moisture content on the shear strength properties of soil was conducted in this study by varying the soil natural moisture content to 2% and then 4% increment at various depth. The soil sample was cored out using drilling method at different depth below the ground surface starting from 400mm to 24.75m for point 1 and 400mm to 11.25m for point 2. Its grain distribution was found by wet sieve analysis, The natural moisture content of each soil sample was determined, other basic experiments that was carried out are specific gravity, Atterberg limit test, sieve analysis. The result from the findings showed that the soils at point 1 and 2 are composed of silt and clay and the soil at point 2 have high plasticity than the soil in point 1. Also from the findings, it was found that soil shears faster at higher moisture content and that the angle of internal friction and cohesion index are inversely related.

The low insertion of the medial arcuate ligament is a rare topographical form which is the cause of an extrinsic compression of the coeliac trunk. In its asymptomatic form, its research is necessary if interventional radiology or above- meso-colonic surgery is required at the risk of compromising the evolution of vascular and/or pancreatico-bilio-digestive therapeutic gestures. The authors report a case of inserted and compressive low medial arcuate ligament of the coeliac trunk.

Bhattacharjee (2017) mentions that sometimes people lie to inflate their image and to cover up bad behavior. The capacity for dishonesty is essential as the need to trust others, which is ironically puzzling to detect. Finally, it would be enunciated that lie is human. Similar to Bhattacharjee, DePaulo et al., (1996) state that people lie continually about their feelings, actions, plans, whereabouts, achievements, and knowledge. This phenomenon fascinates the researchers to carefully probe it in one of TV series entitled 13 Reasons Why (Season 2). In this TV series, the main character, Clay Jansen seems to do some lies due to his capacity in court as the witness of Hannah’s suicide. He indeed does not want to engage in the trial but Hannah’s spirit is haunted him to uncover the case. Employing Cooperative Principles (CP) proposed by Grice (1975) and premises of motivations (instrumental, relational, and identity) of deception by Buller and Burgoon (1996), this investigation is conducted to reveal lying behavior of the main character and his motivations of doing it. Under descriptive qualitative method, the analysis results that all four maxims are violated. It also reveals that Clay employs three lie motivations which disclose his lying behavior. Instrumental motivation is applied to avoid punishment and to protect source of information. Then, relational motivation is exploited to redirect the social interaction and to protect interlocutors’ feeling. Last, identity motivation is operated to protect his private feeling and to project a favorable image.

The hemorrhagic syndrome in its clinical, cutaneous and ocular diversity most often constitutes the circumstances in which acute leukemia is discovered. Digestive mucosal involvement is rarely indicative of serious bone marrow failure, thus posing a problem of etiological diagnosis in a gastroenterological medical setting [1]. In the literature, it varies from 2 to 10-15% depending on the study and is considered a sign of poor prognosis requiring early diagnosis for better management [2]. We report a case of a 59-year-old woman admitted for rectal bleeding associated with an anemic syndrome. The initial clinical examination showed a finger cot stained with bright red blood. The blood count had shown anemia at 6.4g/dl microcytic, normochromic, neutropenia at 1.8x103, thrombocytopenia at 36.103. Colonoscopy and esogastroduodenoscopy were normal. Blood smear and myelogram were in favor of Acute Myeloid Leukemia. Karyotype and immunophenotyping were not performed. Symptomatic treatment was offered. The evolution is marked by the improvement of the clinical signs. This association, acute myeloid leukemia and rectal bleeding is rarely described in the literature.