Digital transformation has become vital for organizations in order for them to differentiate from competitors providing a competitive advantage in the fast-changing environment they operate. Digital transformation is considered as a radical transformation affecting organization’s products, services, people and processes while improving performance. It is a risky and tremendous challenge for most organizations. Based on a dissertation with the current paper an approach on digital transformation, in a national defense company is attempted. Products and services provided are characterized through high quality standards and a strong culture. Those characteristics are considered a fruitable ground for providing a framework to transform an organization into a digital one. Taking into consideration the above, literature research on digital transformation of organizations and their benefits are provided. The digitalization process is analyzed in order to show the building blocks of transforming the organization into a digital one. However, in order to start such a process, the organization has to have an adaptive high performance organization culture. This is considered as the base to start the digitalization process. In order for the organization to have such a culture, current situation has to be assessed and certain actions to be taken. An assessment of above-mentioned company is presented and actions proposed. It is obvious that organizational digital transformation is inextricably linked with an organizational culture change. The benefits and barriers from such a transformation are shown and finally proposals presented regarding a digital strategy implementation as well as a vision and mission statement for the company.

Numb chin syndrome is a rare presentation due to injury to mental nerve characterized by numbness, hypoesthesia, and paresthesia. This syndrome is mostly presented with dental interventions, traumatic injuries, or malignant pathologies. We report a unique case of a 20-year-old male diagnosed with sickle cell disease presented with loss of sensation over right chin area secondary to the vaso-occlusive crisis. This case depicts a complex relationship between neurological complications and hemoglobinopathies of SCD.

Examination is a fundamental instrument to assess the level of acquisition of knowledge and intellectual competence of a student for a particular course or program. The present study highlights a comparative account of annual mode of examination and semester pattern of examination under Choice Based Credit System (CBCS) mode. The study also indicates notable constrains faced in conduction of examination i.e., data management for pre- examination works like preparation of eligible students’ details, examination center management, accurate question statistics, evaluation of answer scripts, marks processing, preservation of grade reports etc. through manual intervention. The ultimate solution is to develop a dedicated examination management system by integration of Information and Communications Technology (ICT) for transformation of the traditional education system to the Outcome Based Education (OBE) system by way of the reformation of examination process.

Background: The enzyme arginase plays a significant role in the growth of many organisms as important biological enzyme. Objective: The study was designed to isolate L-arginase from P. aeruginosa that isolated from sewages and to evaluate the influence of arginase on biofilm-generating bacteria. Materials and Methods: The current study includes 28(54.8%) isolates from soil with 24 (46.2%) from sewage water out of 52 isolated from soil and sewage for the purpose of obtaining Pseudomonas aeruginosa. Using standard laboratory methods to isolate Pseudomonas aeruginosa, 33 isolates were isolated, of which 15 (45.45%) were from soil and 18 (54.54%) from sewage. The study also included 177 different eyes (urinary fluid, excrement, blood, wounds, sputum, and cerebrospinal fluid) of patients suffering from various injuries. Results: The statistical analysis of the isolates indicated that there is a high significant (P≤0.01) for the growth of some types of bacteria, such as P. aeruginosa 30(16.89%), Klebsiella, Serratia 33(18.88%) and Acinetobacter 33(18.88%). While the results showed that Lactobacillus is the lowest number of isolates 7(3.9%). Optimum condition of arginase activity and stability comprising pH level of eight degrees, the temperature of 37℃ is the best conditions for the production of arginine, concentrations of L-arginine substrate (0.1-2.5)g/l on the activity of arginase enzyme for arginine production, The finding also shows that the arginase enzyme exhibited the highest activity after 96 hours of the incubation process L- arginase Purification Assay including Ammonium Sulphate precipitation in (60-80)%, Dialysis, Ion exchange chromatography, Gel filtration. Conclusions: This study concluded that the enzyme arginase had a significant effect on the strong biofilm of pathogenic bacteria.

Driven by global development strategies, both domestic and foreign enterprises tend to utilize international brand advertisements to enhance their visibility and expand their global businesses. Since its accession to the WTO, China has experienced rapid development. Therefore, for Chinese enterprises, the appropriate translation of their product advertisements directly impacts commodity sales and consumer’s brand awareness. Building upon intercultural communication theory, this thesis will further analyze the challenges in intercultural communication as perceived by professional translators and explore their specific solutions through a case study. Subsequently, this essay will provide comprehensive insights into strategies and techniques for translating contemporary Chinese local brand advertisements in the context of intercultural communication.

The research focused on evaluating the groundwater potential in the vicinity of Federal University of Technology Owerri (FUTO) using a resistivity survey method. The investigation involved the utilization of eleven Schlumberger vertical electrical soundings (VES). The data collection was conducted using an ABEM Terrameter SAS4000 and then processed with IPI2Win Software, which relies on the conventional theory of curve matching. This process aimed to determine the depth, quality, and subsurface formations of the groundwater. The VES interpretation results revealed the presence of 3-5 geoelectric layers above the aquiferous layers. Various curve types were identified in the study area, including monotonically ascending (AA), bowed-ascending (HA), bowl-bell (HK), and ascending-bell (AK) curves. The majority of the field curves were found to be of the A-shaped type, signifying specific aquifer characteristics. The study indicated that the depth to the water table is relatively shallow in the Ihiagwa area, with an average depth of 7.26 meters. In contrast, the aquifer's depth is deeper around Avu, Nekede, and Eziobodo areas, with a mean depth of 32.33 meters. Obinze had very deep aquifers, with an average depth of 57.75 meters. Furthermore, the study established a relationship between aquifer characteristics and geoelectric parameters, allowing for the estimation of hydraulic conductivity and transmissivity values at all the sounding locations, even in areas lacking boreholes. These hydraulic characteristics showed that the aquifer had protective capacities ranging from 0.036 to 0.509 mhos, transmissivity values ranging from 11856.32 to 28661.28 m2/day, and hydraulic conductivity ranging from 13.47 to 1009.2 m/day. These values suggested that the aquifer materials are highly permeable, facilitating fluid movement within the aquifer. This research demonstrated the effectiveness of surface geophysics in estimating aquifer hydraulic characteristics, particularly in situations where pumping test data are unavailable. It also highlighted the vulnerability of the aquifer to surface contaminants. The findings are expected to be valuable for the long-term planning of groundwater exploitation projects in the study area.

The main of this study examines the long-run relationship between foreign direct investment and infrastructure on economic growth in Lao PDR using time series data from 1995-2020. The empirical evidence of cointegration among the variables in the long run by Autoregressive Distributed Lag (ARDL) bounds test estimates. The empirical results indicate that the FDI variable has a positive and significant impact on the level of Laos’ economic growth in the long run. Similarly, infrastructure variables such as telecommunication, electricity, and air transport play important roles in supporting economic growth in the long run and there are positive and statistically significant impacts at the level. As a result, to achieve the target of sustainable economic growth the government of Laos should attract and sustain more foreign direct investment and improve the infrastructure such as telecommunication, electricity, and air transport to boost economic growth shortly.

Environmental philosophy aims to prompt an effective human response to connected problems by understanding the unquestioned beliefs and presumptions. Tagore's environmental philosophy differs from other philosophers by promoting a holistic view of the environment. Tagore's environmental thought recognizes the intrinsic value of all living beings and emphasizes a spiritual and conscious transformation in humans' relationship with nature. Ambedkar's ideas are crucial to the dominant discourse, which is characterized by a concern for transforming the natural world to address social issues generated. The focus of this paper is on the impact of Gandhi's, Ambedkar's, and Tagore's environmental thoughts on Indian environmentalism.

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genomics are producing ever-larger reservoirs of rich biodata. The plant needs a significant alteration in metabolism to endure unfavorable environmental stress circumstances, such as drought and environmental stresses. This alteration comprises considerable transcriptome reprogramming upon the onset of the stress and transcription and gene expression regulation. Crops including cotton, maize, and potatoes have benefited from the introduction of many genes obtained from Bacillus thuringiensis. The genes increase the plants' resistance to insect assaults, which lowers or even eliminates the need for certain pesticide treatments. An increasing amount of research suggests that plants' nutritional status in minerals has a major impact on their ability to adapt to harsh environmental conditions. Being complex creatures, plants may face a variety of biotic and abiotic challenges in their natural habitat. A number of biotic and abiotic pressures coincide as a result of global warming, which lowers agricultural production. Different biometrical analyses, including path coefficient, discriminant function, generation means, line x tester, triple test cross, stability parameters, D2 statistics, metroglypth, diallel, partial diallel, triallel, quadriallel, etc., are performed in plant breeding and genetics. Two kinds of food plants, such as Oryza sativa and Arabidopsis thaliana, have had their whole genomes sequenced. The production of ABA involves the enzymes zeaxanthin epoxidase (ZEP), 9-cis-epoxycarotenoid dioxygenase (NCED), and ABA-aldehyde oxidase (AAO). Drought tolerance is increased in plants that overexpress these genes.

Simulation has emerged as an instrumental tool for continuous professional development (CPD) within the nursing profession, providing a controlled environment to replicate real-life healthcare scenarios. This study delves into the multifaceted significance of CPD for nurses and how simulation bridges the theory-practice gap. The integration of simulation into CPD programs offers personalized learning experiences, fostering interprofessional collaboration and enhancing competency and communication skills among healthcare professionals. Real-world examples and case studies demonstrate the positive impact of simulation on nursing practice and patient care. Moreover, this paper explores the diverse modalities of simulation and their applications in different healthcare settings. Simulation, as a conduit between theory and practice, empowers nurses to continually refine their clinical knowledge and skills, ultimately elevating the quality of patient care. This article sheds light on the transformative potential of simulation in revolutionizing the approach to lifelong learning and growth among nurses, emphasizing the pivotal role it plays in the ever-evolving healthcare landscape of the Middle East.

Cardiovascular diseases and infections are the two main causes of mortality in Hemodialysis patients [1, 6]. Health care associated infective endocarditis among them carries higher morbidity and mortality. The following is a case series of 3 Enterococcal endocarditis in HD patients and our experience in the management.

A case of 41-year-old patient presented with left lower leg cellulitis, laboratory investigations showed elevated CK levels of more than 193000 U/L, high pancreatic enzymes level namely amylase & lipase, significant electrolyte and acid base abnormalities. Diagnosis of Rhabdomyolysis made based on CK level results in acute pancreatitis. This patient developed acute renal failure with all above in mind, he stayed inpatient for 19 days. The purpose of this case report is to highlight the unusually high CK with unusual association of acute pancreatitis leading to rhabdo¬myolysis and the associated morbidity.

The research aims to analyze and discover the weaknesses in regulations on criminal sanctions against perpetrators of criminal acts of corruption at this time, and the reconstruction of regulations on criminal sanctions against perpetrators of criminal acts of corruption based on the value of justice using a constructivism paradigm, through direct interviews with informants empirically supported with studies literature through theoretical steps. The research results show that the act of abuse of authority is a form or manifestation of an unlawful act regulated in Article 3 of Law Number 31 of 1999 jo. Law Number 20 of 2001. From the principles of legislative regulation, one of the reasons for the difference in criminal threats in Article 2 and Article 3 of Law Number 31 of 1999 Jo. Law Number 20 of 2001 is the principle of lex specialis derogat lex generalis (specific laws exclude general laws). The difference in the threat of minimum and maximum sentences in Article 2 and Article 3 of the Corruption Crime Law results in Judges imposing different sentences for the same case. Reconstruction of criminal sanctions against perpetrators of criminal acts of corruption based on the value of justice in Article 3 of the Corruption Eradication Law, namely: Every person who, with the aim of benefiting himself or another person or a corporation, abuses the authority, opportunity or means available to him because position or position that could harm state finances or the state economy, shall be punished with life imprisonment or imprisonment for a minimum of 5 (five) years and a maximum of 20 (twenty) years and/or a fine of at least Rp. 50,000,000,- (fifty million rupiah) and a maximum of Rp. 1,000,000,000,- (one billion rupiah).

The research aims to analyze and discover the weaknesses of the regulatory authority of Bhabinkamtibmas in resolving criminal acts through the community policing strategy to realize domestic security at this time and to reconstruct the authority of Bhabinkamtibmas in resolving criminal acts through community policing strategies to realize domestic security based on restorative justice values using a constructivism paradigm, through direct interviews with informants empirically supported with studies literature through theoretical steps. Research Result Show that the Reconstruction of the regulatory authority of Bhabinkamtibmas in resolving criminal acts through a community policing strategy in order to realize domestic security based on restorative justice values can be done by reconstructing Article 15 paragraph (1) letter b of Law Number 2 of 2002 concerning the Police of the Republic of Indonesia, Article 1 number 5, Article Article 3 paragraph (1), and Article 7 of the Regulation of the Head of the National Police of the Republic of Indonesia Number 7 of 2021 concerning Bhayangkara Building Security and Public Order, and Article 1 number 3 of the Regulation of the National Police of the Republic of Indonesia Number 1 of 2021 concerning Community Policing, which is related to the authority of Bhabinkamtibmas with a community policing strategy in resolving all forms of legal violations and other forms of disturbance that can disturb the community in a fair manner with a restorative and rehabilitative approach.